Search clinical trials for: Part A - AZD9291 in combination with AZD6094

Total 680 results

St Vincent's Hospital, Sydney

Recruiting

Seviteronel in Combination With Chemotherapy in Androgen-receptor Positive Metastatic Triple-negative Breast Cancer (4CAST)

Triple Negative Breast Cancer

Australia
Memorial Sloan Kettering Cancer Center

Active, not recruiting

ß-Thalassemia Major With Autologous CD34+ Hematopoietic Progenitor Cells Transduced With TNS9.3.55 a Lentiviral Vector Encoding the Normal Human ß-Globin Gene

Confirmed Diagnosis of ß-thalassemia Major

United States
University of Michigan
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University...

Completed

Parameters of Exercise to Prevent Osteoporosis (OSTEOPOROSISEX)

Osteoporosis, Postmenopausal

United States
Tel-Aviv Sourasky Medical Center
Weizmann Institute of Science

Recruiting

Cyclosporine in Combination With Carfilzomib and Dexamethasone in Relapsed Multiple Myeloma Refractory to Carfilzomib and High Expression of PPIA Gene in Myeloma Cells

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory

Israel
AstraZeneca

Completed

A Global Study to Assess the Effects of MEDI4736 (Durvalumab), Given as Monotherapy or in Combination With Tremelimumab Determined by PD-L1 Expression Versus Standard of Care in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer (ARCTIC)

Non - Small Cell Lung Cancer NSCLC

United States, France, Germany, Italy, United Kingdom, Belgium, Poland, Romania, Taiwan, Thailand, Canada, Korea, Republic of, Czechia, Hungary, Japan, Russian Federation, Hong Kong, Spain, Netherlands, Greece, Australia, Serbia, Bu... and more
Hacettepe University

Completed

Comprehensive Evaluation in Patients With Meniere's Disease

Quality of Life | Physical Disability | Psychosocial Problem | Meniere Disease

Turkey
Technische Universität Dresden
Pfizer; Novartis Pharmaceuticals

Recruiting

Combination of Midostaurin and Gemtuzumab Ozogamicin in First-line Standard Therapy for Acute Myeloid Leukemia (MOSAIC) (MOSAIC)

Acute Myeloid Leukemia

Germany
R&D Cardiologie
St. Antonius Hospital

Unknown

What is the Optimal antiplatElet and Anticoagulant Therapy in Patients With Oral Anticoagulation Undergoing revasculariSaTion 2. (WOEST 2)

Myocardial Infarction | Stroke | Bleeding | Acute Coronary Syndromes | Coronary Artery Diseases | Atrial Fibrillations | Heart Valve Prostheses

Belgium, Netherlands
Zambon SpA

Completed

Clinical Study to Evaluate Z7200 Pharmacokinetics Profile

Asthma

United Kingdom
National Cancer Institute (NCI)

Recruiting

Testing the Safety of the Anti-Cancer Drugs Durvalumab and Olaparib During Radiation Therapy for Locally Advanced Unresectable Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Unresectable Pancreatic Carcinoma | Locally Advanced Pancreatic Carcinoma

United States, Canada
Cetylite Industries

Completed

Experimental Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 Anesthetic Spray in Normal Volunteers

Anesthesia

United States
GlaxoSmithKline

Completed

Outcomes and Costs Associated With Initiating Maintenance Treatment With Fluticasone Propionate 250mcg/Salmeterol Xinafoate 50mcg Combination (FSC) Versus Anticholinergics Including Tiotropium (TIO) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
Ludwig-Maximilians - University of Munich

Completed

Acute Application of Pegvisomant and Octreotide in Acromegaly

Acromegaly

Germany
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anticancer Drug, Olaparib, to the Usual Chemotherapy (Temozolomide) for Advanced Neuroendocrine Cancer

Metastatic Adrenal Gland Pheochromocytoma | Metastatic Paraganglioma | Unresectable Adrenal Gland Pheochromocytoma | Unresectable Paraganglioma | Advanced Adrenal Gland Pheochromocytoma | Advanced Paraganglioma | Stage III Adrenal Gland Pheochromocytoma and Sympathetic Paraganglioma AJCC v8 | Stage...

United States
DSM Nutritional Products, Inc.

Completed

Dermal Irritation, Sensitization and Cumulative Irritation Potential of 6% Bemotrizinol

Sunburn

United States
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; Brown University; University of Southern California; Weill... and other collaborators

Recruiting

Attention and Interpretation Modification (AIM) for Fear of Cancer Recurrence: An Intervention Development Study

Breast Cancer | Rare Cancer

United States
University Hospital, Ghent

Completed

Evaluation of a New Protocol for Adult Procedural Sedation With Ketamine-propofol in a 1 on 4 Ratio

Procedural Sedation and Analgesia

Belgium
Universidade Estadual de Maringá

Unknown

Efficacy of N-Acetyl-Cysteine in Bipolar Disorder and Tobacco Use Disorder (NACBD)

Bipolar Disorder

Brazil
State University of New York at Buffalo

Not yet recruiting

Study to Evaluate the Safety and Efficacy of Bicalutamide in Combination With Sunitinib in Patients With TKIs-resistant RCC

Carcinoma, Renal Cell
Multinational Center for Quality of Life Research...

Unknown

Quality of Life, Symptoms and Treatment Satisfaction in Adult Patients With Relapsed and/or Refractory Multiple Myeloma, Receiving Ixazomib (Ninlaro®) in Combination With Lenalidomide and Dexamethasone in a Real World Setting: Pilot Study

Relapsed and/or Refractory Multiple Myeloma
German Breast Group
AGO Study Group

Completed

Taxol Epirubicin Cyclophosphamide Herceptin Neoadjuvant (TECHNO)

Breast Cancer

Germany
University Medical Center Mainz

Completed

IA or PE - What is the Best Treatment Option of Steroid Refractory Neurological Autoimmune Diseases

Neurological Autoimmune Diseases

Germany
Augusta University
Janssen Scientific Affairs, LLC

Not yet recruiting

Pilot Study Dara-CyBorD in Newly Diagnosed Multiple Myeloma Patients With Renal Failure

Multiple Myeloma | Renal Failure

United States
AbbVie

Completed

A Study to Examine the Effect of Levodopa-Carbidopa Intestinal Gel (LCIG) Therapy Relative to That of Optimized Medical Treatment (OMT) on Non-motor Symptoms (NMS) Associated With Advanced Parkinson's Disease (PD)

Advanced Parkinson's Disease

United States, Australia, Canada, Germany, Greece, Italy, Korea, Republic of, Spain, Sweden
Thrombosis Research Institute

Completed

Overall Survival of Inoperable Gastric/GastroOesophageal Cancer Subjects on Treating With LMWH + Chemotherapy(CT) vs Standard CT (GASTRANOX)

Gastric Cancer | Gastroesophageal Cancer

India
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination With GM-CSF or IL-12 to HIV-Positive Patients

HIV Infections

United States
Centre Hospitalier Universitaire Dijon

Completed

Randomized Trial Sorafenib-Pravastatin Versus Sorafenib Alone for the Palliative Treatment of Child-Pugh A Hepatocellular Carcinoma

Child-Pugh A Hepatocellular Carcinoma

France
University of Nove de Julho

Enrolling by invitation

Photobiomodulation for Controlling Pre-Local Anesthetic Injection Pain

Fear Needles

Brazil
Forest Laboratories

Completed

Efficacy and Safety of Quadruple Therapy in Eradication of H. Pylori: A Comparison to Triple Therapy

Helicobacter Infections

United Kingdom
University Hospital, Lille

Active, not recruiting

Compare Lenalidomide and Subcutaneous Daratumumab vs Lenalidomide and Dexamethasone in Frail Subjects With Previously Untreated Multiple Myeloma Who Are Ineligible for High Dose Therapy (IFM2017_03)

Multiple Myeloma

France
The First Affiliated Hospital of Soochow University

Not yet recruiting

Efficacy and Safety of Daratumumab in Combination With Bortezomib, Thalidomide, and Dexamethasone Regimens in Newly Diagnosed Multiple Myeloma

Newly Diagnosed Multiple Myeloma
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure (MULTI-OCTAVE)

HIV-1 Infection

Kenya, Brazil, South Africa, Uganda, Zimbabwe, India, Malawi, Haiti, Thailand, Peru
University Hospital, Bordeaux

Recruiting

Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. (GENEPI)

Rubinstein-Taybi Syndrome

France
AstraZeneca

Completed

Study to Assess the Bioavailability of Ticagrelor OD Tablet vs. IR Tablet

Healthy Subjects | Bioavailability

Germany
Memorial Sloan Kettering Cancer Center
Tufts Medical Center; Lahey Clinic

Completed

Lenalidomide (Revlimid®) Plus Low-dose Dexamethasone (Ld x 4 Cycles) Then Stem Cell Collection Followed by Randomization to Continued Ld or Stem Cell Transplantation (SCT) Plus Maintenance L

Multiple Myeloma

United States
King's College Hospital NHS Trust
King's College London; Fight for Sight (Funder)

Recruiting

Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER). (TIGER)

Eye Diseases | Macular Degeneration, Wet | Sub-Macular Hemorrhage

United Kingdom
Dong-A University

Completed

Efficacy in Ablative Fractional Laser Assisted Photodynamic Therapy According to Ablative Depth for Actinic Keratosis

Actinic Dermatosis

Korea, Republic of
Celgene

Active, not recruiting

ACY-1215 (Ricolinostat) in Combination With Pomalidomide and Low-dose Dex in Relapsed-and-Refractory Multiple Myeloma

Multiple Myeloma

United States
Cancer Institute and Hospital, Chinese Academy...
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

NALIRIFOX in Combination With Camrelizumab for BRPC: a Prospective, Exploratory Study

Borderline Resectable Pancreatic Cancer

China
Guangxi Medical University

Not yet recruiting

Aprepitant Plus Granisetron and Dexamethasone for the Prevention of Vomiting in Patients With HAIC Therapy for HCC

Hepatocellular Carcinoma
Lowcountry Infectious Diseases

Unknown

Neuroma Injections to Treat Restless Legs Syndrome - RCT

Restless Legs Syndrome

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Monoclonal Antibody 3F8 and Sargramostim in Treating Patients With Neuroblastoma

Neuroblastoma

United States
Skin Laser & Surgery Specialists
Galderma R&D

Terminated

Mirvaso® Gel and Dysport® for Erythema and Flushing of Rosacea

Erythema and Flushing Associated With Rosacea
Memorial Sloan Kettering Cancer Center
Pfizer; Dana-Farber Cancer Institute; University of Pittsburgh; University of Virginia

Completed

Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

Neurofibromatosis | Meningioma | CNS Cancer | Hemangioblastoma | Intracranial Hemangiopericytoma

United States
Celgene

Completed

Phase 1b Study Evaluating ACY-1215 (Ricolinostat) in Combination With Pomalidomide and Dexamethasone in Relapsed or Relapsed-and-Refractory Multiple Myeloma

Multiple Myeloma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Extensive Stage Lung Small Cell Carcinoma

United States
University of the Philippines

Completed

Changes in Vital Signs and Pupil Diameter Related to Pharmacologic Mydriasis in Premature Infants: A Randomized Double Blind Clinical Study

Retinopathy of Prematurity
Mingzhi Zhang

Recruiting

Open Randomized Prospective Clinical Study of R-FPD Versus R-MAD Regimen in the Treatment of Primary Central Nervous System Lymphoma

Primary Central Nervous System Lymphoma

China
Janssen-Cilag G.m.b.H

Completed

Human Immunodeficiency Virus (HIV) Postexposure Prophylaxis (PEP) With Darunavir/Ritonavir (DRV/r) (PEPDar)

Human Immunodeficiency Virus (HIV)

Germany
Assistance Publique - Hôpitaux de Paris

Withdrawn

Evaluation of the Pulmonary Vascular Reactivity Test in Patients With Pulmonary Arterial Hypertension and a Cardiac Shunt (ReVAch)

Pulmonary Arterial Hypertension With Congenital Cardiac Shunt

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