Search clinical trials for: PfSPZ Challenge

Total 579 results

Boston University
National Institute on Aging (NIA)

Recruiting

Multi-Center Development of a Novel Diagnostic Test for Alzheimer's Disease (DTAD)

Alzheimer Disease | Mild Cognitive Impairment

United States
McGill University Health Centre/Research Institute...

Unknown

Fluid Responsiveness in the Postoperative Patient: a Prospective Study

Actual Impaired Fluid Volume
University of Birmingham

Recruiting

Impact of 11-oxygenated Androgens on Metabolic Dysfunction of Women With Polycystic Ovary Syndrome (11OXO-PCOS)

Polycystic Ovary Syndrome

United Kingdom
Vanderbilt University Medical Center

Not yet recruiting

Attentional Mechanisms in SCD (AMoCC-SCD)

Subjective Cognitive Decline

United States
Indiana University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Anti-Angiogenic Preeclampsia Milieu Impairs Infant Lung and Vascular Development

Preeclampsia

United States
VLP Therapeutics

Completed

To Assess the Safety, Immunogenicity and Efficacy of VLPM01 in Healthy, Malaria-Naïve Volunteers

Malaria,Falciparum

United States
National Institute of Allergy and Infectious Diseases...

Completed

Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites

Plasmodium Falciparum Infection

United States
Stiefel, a GSK Company
GlaxoSmithKline

Completed

A Study to Evaluate the Potential of Tazarotene Foam to Cause an Allergic Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers.

Acne Vulgaris

United States
Meir Medical Center

Terminated

Treating Patients With a History of Non-Life Threatening Allergic Reaction to Penicillin With Penicillin

Penicillin Allergy

Israel
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Prematurity-Related Ventilatory Control (PreVent)

Respiratory Control in Premature Infants

United States
Kuopio University Hospital
John Hunter Hospital

Recruiting

Reference Ranges for the Cough Responsiveness to Inhaled Mannitol

Cough

Australia, Finland
University of Washington
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Active, not recruiting

Alcohol & Mobile Phone Study to Reduce High-risk Alcohol Use and Consequences (AMPS)

Alcohol; Use, Problem

United States
GlaxoSmithKline
Walter Reed Army Institute of Research (WRAIR); The PATH Malaria Vaccine Initiative...

Completed

Efficacy, Safety and Immunogenicity Study of GlaxoSmithKline(GSK) Biologicals' Candidate Malaria Vaccine 257049 in the Sporozoite Challenge Model in Healthy Malaria-naïve Adults

Malaria

United States
University of Virginia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Insulin Sensitivity, Impaired Counterregulation, and Glucose Variability (BPK005)

Type 1 Diabetes Mellitus

United States
Immune Targeting Systems Ltd

Completed

Safety, Tolerability, Efficacy and Immunogenicity of an Influenza A Vaccine (FP-01.1) in Healthy Volunteers Following Virus Challenge

Influenza A

United Kingdom
Imperial College London
Novartis Pharmaceuticals

Completed

Repeat Nasal Allergen Challenge

Hayfever

United Kingdom
QOL Medical, LLC

Completed

Adult Pilot Study for Reference Ranges and Optimal Cut-offs for the Sucrose Challenge Test and Sucrose Breath Test

Congenital Sucrase-Isomaltase Deficiency

United States
Lithuanian University of Health Sciences

Completed

Focused Assessed Echocardiography to Predict Fluid Responsiveness (fluidres)

Surgery | Hypotension | Hypovolemia
University of Oxford
British Heart Foundation; National Institute for Health Research, United Kingdom

Completed

Iron Status and Hypoxic Pulmonary Vascular Responses

Pulmonary Arterial Hypertension | Iron Deficiency | Lung Hypoxia

United Kingdom
U.S. Army Medical Research and Development Command
U.S. Army Office of the Surgeon General

Completed

Shigella Flexneri 2a Invaplex 50 Vaccine Dose Finding and Assessment of Protection

Shigellosis

United States
Universitaire Ziekenhuizen KU Leuven

Completed

The Functional Consequences of the CTNS-deletion for the TRPV1-receptor in Cystinosis Patients

Cystinosis

Belgium
National Institute of Allergy and Infectious Diseases...

Completed

Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa...

Malaria

Mali
National Taiwan University Hospital
Ministry of Science and Technology, Taiwan; National Taiwan University; National...

Recruiting

A Lego Robot Programming Intervention for Enhancing Older Adult Cognitive Health

Cognitive Inferential Ability

Taiwan
University of Manitoba
Health Sciences Centre, Winnipeg, Manitoba; Natural Sciences and Engineering...

Recruiting

Non-Invasive Mapping of Cerebral Autoregulation Using Near Infrared Spectroscopy

Cerebral Autoregulation Mapping

Canada
King's College London
King's College Hospital NHS Trust; University College London Hospitals; Cambridge... and other collaborators

Recruiting

The Clinical Impact of the Basophil Activation Test to Diagnose Food Allergy

Egg Allergy | Food Allergy | Food Allergy in Children | Milk Allergy | Food Allergy in Infants | Nut Allergy | Food Allergen Sensitisation

United Kingdom
GlaxoSmithKline
The PATH Malaria Vaccine Initiative (MVI)

Completed

Efficacy, Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Evaluating Different Dose Schedules in a Sporozoite Challenge Model in Healthy Malaria-naïve Adults

Malaria

United States
University of Maryland, Baltimore

Active, not recruiting

Shigella CVD 30000: Study of Responses to Vaccination With Shigella Vaccine

Shigella

United States
Postgraduate Institute of Medical Education and...

Completed

A Study to Compare the Efficacy and Safety of Intrapleural Doxycycline Versus Iodopovidone for Performing Pleurodesis in Malignant Pleural Effusion

Malignant Pleural Effusion

India
Shield Therapeutics

Completed

Safety and Efficacy Study of Oral Ferric Iron To Treat Iron Deficiency Anaemia in Quiescent Crohn's Disease (AEGIS-2) (AEGIS-2)

Crohn's Disease | Inflammatory Bowel Disease | Iron Deficiency Anaemia
Johns Hopkins University

Completed

Exercise and Cognition Trials (EXACT)

Alteration of Cognitive Function

United States
Johns Hopkins University

Completed

Do More, B'More, Live Fit

Physical Activity | Cystic Fibrosis
Vanderbilt University Medical Center

Recruiting

Cholinergic Mechanisms of Attention in Aging

Subjective Cognitive Decline

United States
University of Wyoming

Completed

Examining Expectancy Challenges to Prevent Nonmedical Prescription Stimulant Use

Prescription Drug Abuse (Not Dependent)

United States
San Camillo Hospital, Rome
Azienda Ospedaliero Universitaria, Santa Maria della Misericordia di Udine...

Recruiting

Predictive Value of Vasodilator Challenge for Right Heart Failure After LVAD Implantation (PREVV-RHF-LVAD)

Right Heart Failure

Italy
University of Zurich
University of Basel

Recruiting

Oxytocin Administration Prior Planned Caesarean Section

Respiratory Insufficiency Syndrome of Newborn | Breastfeeding Status

Switzerland
ILiAD Biotechnologies

Completed

Pertussis Challenge Study in Adults Vaccinated With BPZE1 (CHAMPION-1)

Pertussis/Whooping Cough | Bordetella Pertussis, Whooping Cough

United Kingdom
Mount St. Mary's College, Los Angeles, CA

Unknown

The Effects of Pain and the Memory of Pain on Autonomic and Neuromuscular Function

Pain

United States
Stanford University

Recruiting

Sex Differences in Coronary Pathophysiology

Ischemia | Chest Pain

United States
Ankara City Hospital Bilkent

Recruiting

Evaluation of Fluid Responsiveness With Pulse Variation Index and Systolic Blood Pressure Changes After Lung Recruitment Maneuver

Fluid Responsiveness | Pleth Variability Index | Lung Recruitment Maneuver

Turkey
Austin Health

Completed

The Use of Penicillin Allergy Clinical Decision Rule to Enable Direct Oral Penicillin Challenge (PALACE)

Hypersensitivity, Immediate | Hypersensitivity, Delayed | Hypersensitivity Response

United States, Australia, Canada
Fundacion CRIS de Investigación para Vencer el...
Apices Soluciones S.L.; Amgen

Completed

Skin Toxicity in Patients With Metastatic Colorectal Cancer Treated With Anti-EGFR and Chemotherapy (DERMIA) (DERMIA)

Skin Toxicity

Spain
Mundipharma AB

Completed

Mannitol Challenge Test in Adult Asthma Patients With Fixed Dose Combinations

Asthma

Sweden
University of Dundee

Completed

Steroid Titration Against Mannitol IN Asthma

Asthma
Dong-Min Kim

Completed

Controlled Trial: 5-day Course of Telithromycin Versus Doxycycline for the Treatment of Mild to Moderate Scrub Typhus

Scrub Typhus

Korea, Republic of
University of Arizona

Completed

Fall Prevention in Older Adults Study

Accidental Fall | Postural Balance

United States
Meir Medical Center

Completed

Extended Open Challenge in Patients With a History of Drug Eruption Following Beta-lactam Treatment

Beta-lactam Allergy

Israel
Radboud University Medical Center
Bill and Melinda Gates Foundation

Completed

Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection (BMGF2b)

Malaria

Netherlands
University of Manitoba
The Hospital for Sick Children; University of British Columbia; McGill University

Enrolling by invitation

Predictors of Persistent Peanut Allergy at Age 5 Years

Allergy to Peanut
PATH
University of Maryland, Baltimore; Pharmaron

Completed

Cholera Anti-Secretory Treatment Trial (CAST)

Cholera

United States
St George's, University of London
University of British Columbia; Bill and Melinda Gates Foundation; Wellcome Trust and other collaborators

Completed

Human Innate Immune Responses To Mycobacterial Aerodigestive Tract Infection (UBC-INNATE01)

Bacterial Infections

United Kingdom

Search clinical trials for: PfSPZ Challenge

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