Search clinical trials for: Pharmacodynamic Studies

Total 818 results

Amir Mortazavi
National Cancer Institute (NCI); Arno Therapeutics

Completed

AR-42 in Treating Patients With Advanced or Relapsed Multiple Myeloma, Chronic Lymphocytic Leukemia, or Lymphoma

Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse... and other conditions

United States
Ohio State University Comprehensive Cancer Center
Amgen

Completed

Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL)

Hematopoietic/Lymphoid Cancer | Recurrent Small Lymphocytic Lymphoma | B-cell Chronic Lymphocytic Leukemia | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia

United States
Kari Kendra
Karyopharm Therapeutics Inc

Completed

Evaluating SINE KPT-330 in Treating Patients With Melanoma That Cannot Be Removed By Surgery (KPT-330)

Recurrent Melanoma

United States
Assistance Publique - Hôpitaux de Paris
Boston Scientific Corporation

Unknown

A Prospective Study for the Treatment of Severe Pulmonary Embolism With Pharmacodynamic Thrombectomy (RESPIRE)

Pulmonary Embolism

France
Bhavana Konda
National Comprehensive Cancer Network

Active, not recruiting

Dabrafenib With or Without Trametinib in Treating Patients With Recurrent Thyroid Cancer

Insular Thyroid Cancer | Recurrent Thyroid Cancer | Papillary Thyroid Cancer | Follicular Thyroid Cancer

United States
Kami Maddocks, MD
Novartis

Completed

Study of BKM120 & Rituximab in Patients With Relapsed or Refractory Indolent B-Cell Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

IACS-010759 in Advanced Cancers

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditions

United States
National Institute of General Medical Sciences...
National Institute of Environmental Health Sciences (NIEHS); Indiana University... and other collaborators

Unknown

Aromatase Inhibitor Clinical Trial

Breast Cancer

United States
Assiut University

Not yet recruiting

Neonatal Seizures in NICU of Assuit University Children's Hospital

Neonatal Seizure
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Epacadostat and Pembrolizumab Before Surgery in Treating Participants With Stage II-III Esophageal or Gastroesophageal Cancer

Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Gastroesophageal Junction Adenocarcinoma

United States
Rennes University Hospital

Completed

Immunosuppressive Therapy Optimization: Development of a Population Pharmacokinetic-pharmacodynamic (PK-PD) Model in Liver Transplantation (OPTILTH)

Liver Transplantation

France
University of Louisville

Recruiting

Esophageal and Gastric Registry and Biorepository

Gastro Esophageal Reflux

United States
Fundación Pública Andaluza Progreso y Salud

Completed

Study of the Impact of the Minimum Inhibitory Concentration and Susceptible Cut-off Points (CLSI, EUCAST, and Pharmacokinetics/Pharmacodynamics)in Prognosis of Bacteremia by Enterobacteriaceae (BACTERIEMIA)

Bacteremia by Enterobacteriaceae

Spain
Duke University

Active, not recruiting

The MURDOCK Study Registry and Biorepository Horizon 1.5 (MURDOCK)

Chronic Disease | Healthy Volunteers

United States
Alexandria University

Completed

Is Preoperative Urodynamics Essential for Women With Pelvic Organ Prolapse (urodynaemics)

Urogenital Prolapse

Egypt
Duke University

Completed

Implementing a Physical and Cognitive Performance Assessment Cohort in the MURDOCK Study Community Registry and Biorepository (PPS)

Aging | Cognitive Functioning | Fitness | Physical Functioning

United States
AORTICA Group
Instituto de Investigación Biomédica de Salamanca

Unknown

Cardiotoxicity in the Elderly (CARTIER)

Elderly | Cardiotoxicity | Cardiac Magnetic Resonance

Spain
Thomas Jefferson University
AstraZeneca

Completed

The Influence of Hypnotic Medications on Sleep Arousal and Its Effect on Gastroesophageal Reflux

Gastroesophageal Reflux

United States
Pierluigi Porcu
Millennium Pharmaceuticals, Inc.; Celgene Corporation

Completed

Bortezomib and Azacitidine in Treating Patients With Relapsed or Refractory T-Cell Lymphoma

Peripheral T-cell Lymphoma | Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Adult Nasal Type Extranodal NK/T-cell Lymphoma | Hepatosplenic T-cell Lymphoma | Post-transplant Lymphoproliferative Disorder | Recurrent Adult T-cell Leukemia/Lymphoma | Recurrent Cutaneous T-cell... and other conditions

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

A Multi-omics Study of "Healthy" Premature CAD Patients

Coronary Artery Disease

China
Tufts University

Completed

Epigenomic and Metabolomic Signatures of APOA2 Gene by Saturated Fat Interaction

Body Mass Index

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Prospective Phenotyping for Genetic Subtypes of Early-onset Atrial Fibrillation

Atrial Fibrillation

United States
dr. Laura C. G. de Graaff-Herder

Recruiting

GROWing Up With Rare GENEtic Syndromes (GROW UR GENES)

Disorders of Sex Development | Congenital Adrenal Hyperplasia | Tuberous Sclerosis | Kallmann Syndrome | Prader-Willi Syndrome | Neurofibromatosis | Rett Syndrome | 22q11 Deletion Syndrome | Turner Syndrome | Noonan Syndrome | Allan-Herndon-Dudley Syndrome | Saethre-Chotzen Syndrome | Congenital Hypopituitarism | Cornelia... and other conditions

Netherlands
NHS Lothian
University of Edinburgh; Action Medical Research

Completed

Investigation of Sleep Quality and Prevalence of Sleep-disordered Breathing in Children and Young People With Epilepsy

Epilepsy | Obstructive Sleep Apnea

United Kingdom
University of Arizona
National Cancer Institute (NCI)

Terminated

Alpelisib in Treating Participants With Transorally Resectable HPV-Associated Stage I-IVA Oropharyngeal Cancer

HPV Positive Oropharyngeal Squamous Cell Carcinoma | Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7 | CDKN2A-p16 Positive | Stage I Oropharyngeal Squamous Cell Carcinoma AJCC V7 | Stage II Oropharyngeal Squamous Cell Carcinoma...

United States
Marwa Mohamed Farag

Completed

Anemia of Prematurity and Hemodynamics

Premature

Egypt
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); University of Southern California

Completed

Methylated Genes in Blood as Biomarkers for Advanced Lung Cancer

Lung Cancer

United States
Rabin Medical Center
Pfizer

Unknown

Direct Oral Anticoagulants Pharmacodynamics in Octogenarian Patients With Atrial Fibrillation

Atrial Fibrillation and Flutter

Israel
Sohag University

Recruiting

Role of Ultrasonography in the Diagnosis of Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

Egypt
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study of the Physical and Emotional Needs of Parents Caring for Children Receiving Chemotherapy for Acute Lymphoblastic Leukemia

Leukemia

United States, Canada, Australia, Switzerland, Puerto Rico, Netherlands
Universidad Complutense de Madrid
Ministerio de Economía y Competitividad, Spain

Not yet recruiting

Relationship Between Major Depression and Periodontal Diseases (LeakyBraInCS)

Periodontitis | Major Depressive Disorder

Spain
University Hospital, Bordeaux

Completed

Cell-free Circulating DNA in Primary Cutaneous Lymphomas (MATULILA)

Mycosis Fungoides | Lymphoma, Large B-cell, Diffuse

France
Sohag University

Not yet recruiting

Histochemical Study of Vitiligo in Sohag University Hospital Patients

Vitiligo

Egypt
Sultan Abdulhamid Han Training and Research Hospital...

Recruiting

Correlation of Different Ultrasonographic Indices With Clinical Parameters in Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

Turkey
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Study of the Safety of MRI Scans in People Who Have Breast Tissue Expanders After Mastectomy

Breast Cancer | Breast Neoplasms | Breast Adenocarcinoma

United States
National Institute of Health and Nutrition
Purdue University

Completed

Development of a Total Nutrient Index

Diet Habit
University Hospital, Montpellier

Completed

Study of Tissue Samples From Patients With Glioma or Other Brain Tumors

Central Nervous System Lymphoma

France
Oslo University Hospital
Danish Pain Research Center; University Hospital of North Norway; University... and other collaborators

Recruiting

Exploring the Genetics of Neuropathic Pain (GeNeup)

Neuropathic Pain | Polyneuropathies | Genetic Predisposition

Norway
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); University of South Florida

Recruiting

Improving Care After Inherited Cancer Testing (IMPACT)

Breast Cancer | Colorectal Cancer | Prostate Cancer | Endometrial Cancer | Inherited Cancer Syndrome

United States
Zhujiang Hospital
Nanfang Hospital of Southern Medical University; First Affiliated Hospital... and other collaborators

Recruiting

A Multicenter Cohort Study on Maternal and Infant Microecology and New Targets for Pre-eclampsia Screening in China (CALM2001)

Preeclampsia | Microbiome

China
Çankırı Karatekin University

Completed

The Effect of Dramatization Simulation on Nursing Students' Ethical Attitudes (Ethical)

ETIC

Turkey
Momentum Data
Pfizer; University of Oxford; University of Surrey

Completed

The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata

Multiple Sclerosis | Pneumonia | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Anxiety Disorders | Psoriasis | Asthma | Type 1 Diabetes | Graves Disease | Celiac Disease | Allergic Rhinitis | Urinary Tract Infections | Crohn Disease | Influenza | Ulcerative Colitis | Herpes Zoster | Herpes Simplex | Atopic Dermatitis | V... and other conditions

United Kingdom
NYU Langone Health

Withdrawn

Tuberculosis Research Blood Bank

Tuberculosis

United States
University of Chicago

Completed

Chicago Childhood Diabetes Registry

Diabetes Mellitus

United States
National Cancer Institute (NCI)

Terminated

Benzoylphenylurea in Treating Patients With Advanced Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
IRCCS San Raffaele

Recruiting

Asymptomatic Small Pancreatic Endocrine Neoplasms. (ASPEN)

Non Functioning Pancreatic Endocrine Tumor

Italy
Ain Shams University

Completed

Iron Status and Lung Function in Pediatric Asthma

Pulmonary Function Tests

Egypt
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S8516-S8736-S9125-S9240 Research Study of Genes in Tissue Samples From Patients With B-cell Non-Hodgkin Lymphoma

Lymphoma
Liga Panamericana de Asociaciones de Reumatologia...
Janssen Research & Development, LLC

Recruiting

Serological and Urinary Biomarkers in Latin American Patients With Systemic Lupus Erythematosus: GLADEL 2.0 Cohort

Lupus Nephritis

Argentina
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Central Pain Syndrome in Survivors of Head and Neck Cancer

Head and Neck Cancer

United States

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