Search clinical trials for: Placebo MDI HFA

Total 59852 results

AstraZeneca

Recruiting

Study to Assess Effect of HFO MDI Propellant on Mucociliary Clearance Compared to HFA MDI Propellant in Healthy Participants

Mucociliary Clearance

United States
AstraZeneca

Completed

Study to Assess Bronchospasm Potentially Induced by HFO vs HFA MDI in Participants With Well/Partially Controlled Asthma

Asthma

United States
AstraZeneca

Completed

A Study to Assess the Safety of Budesonide/Glycopyrronium/Formoterol Fumarate With the Hydrofluoroolefin Propellant in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

United States, Canada, Germany, Argentina, Bulgaria, Poland, Turkey, Mexico, United Kingdom
Boehringer Ingelheim

Completed

Safety and Tolerability of COMBIVENT® HFA as Compared to COMBIVENT® CFC and Placebo HFA in Healthy Male and Female Subjects

Healthy
AstraZeneca
Parexel

Not yet recruiting

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).

Healthy
AstraZeneca

Not yet recruiting

A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
AstraZeneca

Recruiting

Study to Assess the Pharmacokinetic Bioequivalence of Budesonide and Albuterol With an Alternate Propellant Compared to Current Propellant.

Heathy Participants

United States
AstraZeneca

Recruiting

A Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Compared to BGF Formulated With a New Propellant (HFO) in Participants 40 to 80 Years of Age With COPD

COPD (Chronic Obstructive Pulmonary Disease)

United States, Turkey, Vietnam, Malaysia, Philippines, Thailand, Hungary, Mexico, Korea, Republic of, Argentina, Canada, India, Bulgaria, Poland
Sunovion

Completed

Safety and Tolerability Study of Levalbuterol HFA and Racemic Albuterol HFA in Pediatrics Subjects With Asthma

Asthma

United States
Boehringer Ingelheim

Terminated

Comparison of Safety and Efficacy of COMBIVENT HFA to COMBIVENT (CFC) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
Boehringer Ingelheim

Completed

A Confirmation Study of Combivent HFA Inhalation Aerosol in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline

Completed

Efficacy and Safety of Fluticasone Propionate(FP)/ Salmeterol Xinafoate (SLM) Hydro Fluoro Alkane (HFA) Metered Dose Inhaler (MDI) in Pediatric Patients With Bronchial Asthma

Asthma

Japan
Wills Eye
Olleyes, Inc.

Completed

visuALL Field Analyzer (vFA) Compared to Standard Humphrey Automated Perimetry

Glaucoma, Open-Angle

United States
Chiesi Farmaceutici S.p.A.

Completed

Study to Assess the Effect of the New HFA-152a Propellant on Mucociliary Clearance

Mucociliary Clearance

United Kingdom
Jenny Kallunki
Region Östergötland; Malmö University; Eklund foundation Malmö; Swedish Dental...

Active, not recruiting

Treatment of Class II Malocclusion With Excessive Overjet

Quality of Life | Orthodontic Appliances | Class II Malocclusion, Division 1 | Costs and Cost Analysis

Sweden
Lupin, Inc.

Completed

Pharmacodynamic Bioequivalence of Metered Dose Inhalers of Albuterol Sulfate in Patients With Stable Mild Asthma

Mild Persistent Asthma

United States
AstraZeneca
Parexel

Completed

A Study to Assess Drug Absorption of Fixed Dose Combinations of Budesonide, Glycopyrronium, and Formoterol

Chronic Obstructive Pulmonary Disease (COPD)

United States
Sunovion

Completed

Safety and Tolerability Study of Levalbuterol HFA Compared to Racemic Albuterol HFA in Subjects With Asthma

Asthma

United States
Sunovion

Completed

A Safety and Tolerability Study of Levalbuterol HFA Metered Dose Inhaler in Subjects With Asthma

Asthma

United States
AstraZeneca
Parexel

Completed

A Study to Assess the Total Systemic Exposure Bioequivalence of of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA

Chronic Obstructive Pulmonary Disease

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Comparative Effectiveness of a Breath-operated Albuterol Inhaler in Asthma Patients With Poor Inhaler Technique

Asthma

United States
University Medical Center Groningen
Boston Scientific Corporation

Not yet recruiting

Pulsed Field Ablation Versus Conventional Radiofrequency Catheter Ablation for Repeat PVI in Patients With Paroxysmal AF (REPEAT-AF)

Atrial Fibrillation Recurrent
University of Florida
GlaxoSmithKline

Completed

Effect of Age and Device on Delivery of Fluticasone

Asthma

United States
Texas Christian University

Unknown

Hunger, Satiety, and Metabolic Responses to High-fat Meals of Varying Fatty Acid Composition

Body Weight Changes

United States
Hospital de Clinicas de Porto Alegre
Federal University of Rio Grande do Sul; Coordenação de Aperfeiçoamento de...

Completed

Glycemic and Insulinemic Response With Different Sources of Soluble Fiber in Patients Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2 | Dietary Modification | Insulin Tolerance | Diabetic Blood Glucose Monitoring

Brazil
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Comparison of Two Bronchodilator Inhalers in Adolescents and Adults With Exercise-Induced Asthma

Exercise-induced Bronchospasm

United States
Amphastar Pharmaceuticals, Inc.

Terminated

Controlled, 12-Week Study of Albuterol HFA Versus the Active Control, Proventil(R)-HFA in Asthmatic Patients

Asthma

United States
Amphastar Pharmaceuticals, Inc.

Terminated

Single-Dose Cross-Over Study of the Effects of Albuterol-HFA in Exercise Induced Bronchoconstriction

Asthma | Bronchospasm

United States
AstraZeneca
Parexel

Completed

Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA

Chronic Obstructive Pulmonary Disease

United States
Amphastar Pharmaceuticals, Inc.

Completed

Evaluation of Efficacy and Safety for Single Dose of E004 in Children With Asthma

Asthma

United States
Sunovion

Completed

Long Term Safety Study of Levalbuterol and Racemic Albuterol in Subjects Twelve Years of Age and Older With Asthma

Asthma

United States, Canada
Chiesi Farmaceutici S.p.A.

Recruiting

Comparison Between CHF5993 pMDI 200/6/12,5mg HFA-152a VS CHF5993 pMDI 200/6/12,5mg HFA-134a in Subjects With Asthma (Trecos) (TRECOS)

Asthma

United Kingdom
University of Florida
GlaxoSmithKline

Completed

Impact of Anti-static Chamber/Mask

Asthma

United States
University of Dundee

Completed

Does Extra-fine Hydrofluoroalkane-beclomethasone Dipropionate (HFA-BDP) Suppress Small Airways Inflammation in Chronic Obstructive Pulmonary Disease (COPD)?

COPD

United Kingdom
BIO-CAT Microbials, LLC
KGK Science Inc.

Completed

A Study to Evaluate the Effect of GFA-918 on Serum Triglyceride Levels in Individuals With Elevated Serum Triglyceride

Elevated Triglycerides

Canada
Amphastar Pharmaceuticals, Inc.

Completed

Evaluation of Efficacy and Safety of E004 in Children With Asthma

Asthma

United States
Rutgers, The State University of New Jersey

Completed

Lean and Obese: Dietary Inflammation (LODI)

Inflammation | Obesity | Dietary Fat

United States
Boehringer Ingelheim

Completed

Serial Lung Function Measurements in Healthy and Mild Asthmatic Adults After Oral Inhalation of Ethanolic Solutions Containing Two Concentrations of the Excipient Butylated Hydroxytoluene (BHT) Administered With the Respimat® B (RMT-B)

Asthma
Carl Zeiss Meditec, Inc.

Unknown

Glaucoma HFA / OCT Specificity Study

Glaucoma

United States
Sunovion

Completed

Clinical Trial to Assess the Efficacy and Safety of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol for the Treatment of Seasonal Allergic Rhinitis (SAR) to Mountain Cedar in Subjects 12 Years and Older

Seasonal Allergic Rhinitis

United States
Sunovion

Completed

A 6 Month Safety and Efficacy Study of Once Daily Ciclesonide Hydrofluoroalkane (HFA) in the Treatment of Perennial Allergic Rhinitis (PAR) in Subjects 12 Years and Older

Allergic Rhinitis | Perennial Allergic Rhinitis

United States
Pearl Therapeutics, Inc.

Completed

PT001 MDI Versus Atrovent Study in Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States
FLUIDDA nv

Completed

Compare the Effects of Seretide® Evohaler and a Generic Salmeterol/Fluticasone Hydrofluoroalkane (HFA) Pressurized Metered-dose Inhaler (pMDI) on Functional Respiratory Imaging Parameters in Asthmatic Patients

Asthma

Belgium
MDRC
Johns Hopkins University; Columbia University; University of Georgia; Mathematica... and other collaborators

Active, not recruiting

Mother and Infant Home Visiting Program Evaluation (MIHOPE)

Pregnancy | Infant Development

United States
Vanderbilt University
Robert C. Atkins Foundation

Completed

High Fat Diet: Oxidative and Cardiovascular Effects (AFN)

Obesity

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Clinical Study to Evaluate the Pharmacokinetics and Safety of BDP HFA Nasal Aerosol

Allergic Rhinitis
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Dose-ranging Study to Evaluate Albuterol and Hydrofluoroalkane in Subjects Ages 12 and Older With Persistent Asthma

Asthma

United States
Concentrx Pharmaceuticals, Inc.
PharPoint Research, Inc.; Kramer Consulting, LLC

Completed

Safety and Pharmacokinetics of Halix(TM) Albuterol Unit Dose Disposable Inhaler Versus Albuterol MDI

Asthma

United States
Acessa Health, Inc.

Active, not recruiting

Post Market TRUST - U.S.A. Study

Symptomatic Uterine Fibroids

United States
Boehringer Ingelheim

Terminated

Respimat® Inhaler vs a Metered Dose Inhaler Using Berodual® in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

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