Search clinical trials for: Placebo multiple ascending doses

Total 1667 results

ACADIA Pharmaceuticals Inc.

Completed

Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy

Acute Postoperative Pain | Bunionectomy

United States
ACADIA Pharmaceuticals Inc.

Terminated

Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee

Osteoarthritis Pain

United States
Oryzon Genomics S.A.
Alzheimer's Drug Discovery Foundation

Completed

Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease (ETHERAL-US)

Mild to Moderate Alzheimer's Disease

United States
Children's Hospital Medical Center, Cincinnati

Completed

An Initial Study of AZD7325 in Adults With Fragile X Syndrome

Fragile X Syndrome

United States
Thomas Jefferson University

Completed

Gluten Ingestion Biomarkers in Patients w Gluten Sensitivity and Healthy Controls Peptides in Patients With Non-celiac Gluten Sensitivity and Healthy Patients: A Placebo-controlled Study (NCGS)

Non Celiac Gluten Sensitivity

United States
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety Study for Cognitive Deficits in Adult Subjects With Schizophrenia

Cognitive Deficits in Schizophrenia

United States
The Hospital for Sick Children

Terminated

Impact of Emergency Department Probiotic Treatment of Diarrheal Illness on Daycare Attendance

Gastroenteritis

Canada
Dennis Charney

Completed

Intranasal Administration of Neuropeptide Y in Healthy Male Volunteers (NPY)

Anxiety Disorders | Mood Disorder

United States
Circassia Limited
Cetero Research, San Antonio; Adiga Life Sciences, Inc.

Completed

Cat-PAD Follow on Study

Cat Allergy | Rhinoconjunctivitis

Canada
Pulmongene Ltd.

Completed

A First in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of PMG1015

Idiopathic Pulmonary Fibrosis

Australia
Sun Pharmaceutical Industries Limited
Moebius Medical Ltd.; Nordic Bioscience Clinical Development (NBCD)

Completed

Efficacy and Safety of MM-II for Treatment of Knee Pain in Subjects With Symptomatic Knee Osteoarthritis

Osteoarthritis of Knee

United States, Denmark, Hong Kong
Theravance Biopharma

Completed

Multiple Dose Ethnobridging PK Study in Healthy Subjects

Inflammatory Bowel Diseases | IBD

United States
Mitsubishi Tanabe Pharma Corporation

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Multiple Doses of MT-8554 in Female Subjects Experiencing Vasomotor Symptoms

Vasomotor Symptoms

Germany
Chr Hansen

Completed

Efficacy of a Probiotic Strain on Level of Markers of Inflammation in an Elderly Population

Inflammation

Ireland
Gustave Roussy, Cancer Campus, Grand Paris
LinKinVax

Recruiting

Therapeutic Vaccine in Patients With Human Papillomavirus HPV-positive Oropharyngeal Cancer (HPVDCVax)

Head and Neck Carcinoma | Adult Disease

France
Novo Nordisk A/S

Completed

A Research Study Looking at How 50 mg Semaglutide Daily Affects Food Intake and Emptying of the Stomach in People With Obesity

Obesity

Germany
Cortria Corporation

Completed

A Study to Evaluate the Lipid Regulating Effects of TRIA-662

Hyperlipidemia
Pharnext SA

Completed

Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PLEO-CMT) (PLEO-CMT)

Charcot-Marie-Tooth Disease Type 1A

United States, United Kingdom, Belgium, Canada, France, Netherlands, Spain, Germany
Microphyt
Texas A&M University

Completed

Effect of BrainPhyt High Dose on Cognitive Function in Healthy Older Individuals (PHAEO-FOUR)

Age-associated Memory Impairment

United States
Islamic Azad University of Mashhad

Completed

Evaluation of Low Dose Laser in Treatment of Tinnitus

Subjective Tinnitus
Jiangsu Province Centers for Disease Control and...
West China Hospital

Completed

A Phase Ⅱ Clinical Trial of Recombinant Corona Virus Disease-19 (COVID-19) Vaccine (Sf9 Cells)

COVID-19

China
Taiho Pharmaceutical Co., Ltd.

Recruiting

A Phase 2a Study of TAS5315 in Patients With Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria

Japan
Shanghai Pharmaceuticals Holding Co., Ltd
R&G Pharma Studies Co.,Ltd.

Completed

Safety and Efficacy of SPH3127 on Treating Mild-moderate Essential Hypertension Patients

Hypertension,Essential

China
Rennes University Hospital

Recruiting

VIRTUOSE : Efficiency of Sildenafil on the Absolute Claudication Distance of Peripheral Arterial Disease Patients With Intermittent Claudication. (VIRTUOSE)

Peripheral Artery Disease

France
Osel, Inc.
University of California, San Francisco

Completed

Safety Study of Lactobacillus Administered Vaginally to Healthy Women

Bacterial Vaginosis

United States
Bayer

Terminated

A Study to Learn How Safe Study Drug BAY2413555 is, How it Affects the Body, and How it Moves Into, Through, and Out of the Body Over 4 Weeks of Use in Participants With Heart Failure and Implanted Cardiac Defibrillator or Cardiac Resynchronization Devices (ICD/CRT) (REMOTE-HF)

Chronic Heart Failure

United States, Spain, Denmark, Israel, Germany, Italy
Société des Produits Nestlé (SPN)

Completed

Growth, Safety and Efficacy of a Probiotic Supplement (Clara)

Probiotic Supplement

Philippines
Jeil Pharmaceutical Co., Ltd.

Unknown

Clinical Trial to Evaluate the Efficacy and Safety of JPI-289 in Patients With Acute Ischemic Stroke

Acute Ischemic Stroke

Korea, Republic of
University of North Carolina, Chapel Hill
Naturex SA

Completed

Botanical Supplement Muscle Function and Lean Body Mass

Healthy Volunteers

United States
Glenmark Pharmaceuticals Ltd. India
Glenmark Pharmaceuticals S.A.

Withdrawn

A Clinical Trial to Study the Effects of GRC 17536 in Patients With Painful Diabetic Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients)

Painful Diabetic Neuropathy

Germany, United Kingdom
Trevena Inc.

Completed

A Study to Explore the Efficacy of TRV027 in Patients Hospitalized for Acute Decompensated Heart Failure (BLAST-AHF)

Acute Decompensated Heart Failure

United States, Bulgaria, Poland, Russian Federation, Germany, Romania, Argentina, Canada, Czechia, Hungary, Israel, Slovakia
Xintian Pharmaceutical

Not yet recruiting

Efficacy and Safety of Prunella Oral Liquid in the Treatment of Thyroid Nodules (ESPTTN)

Thyroid Nodule

China
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK2339345.

Cough

United Kingdom
Alterity Therapeutics

Recruiting

Study of ATH434 in Participants With Multiple System Atrophy

Multiple System Atrophy

United States, Australia, New Zealand, United Kingdom, Italy, France, Austria
Beijing Konruns Pharmaceutical Co., Ltd.

Completed

The Effect of Jincaopian Tablets on Chronic Pelvic Pain After Pelvic Inflammatory Disease

Chronic Pelvic Pain

China
MiMedx Group, Inc.

Completed

Evaluation of Amniotic Fluid Product in Knee Osteoarthritis

Osteoarthritis of the Knee

United States
Galderma R&D

Completed

Safety and Efficacy of Nemolizumab in PN

Prurigo Nodularis

Germany, Poland, France, Austria
KBio Inc

Completed

Study to Evaluate the Safety and Immunogenicity of KBP-V001 Quadrivalent Influenza Vaccine in Healthy Adults

Influenza

United States
CinDome Pharma, Inc.

Completed

A Phase 2 Study of CIN-102 in Adults With Idiopathic and Diabetic Gastroparesis

Gastroparesis

United States
Boehringer Ingelheim

Completed

Dose Finding, Efficacy and Safety of BI 655064 in Patients With Active Lupus Nephritis

Lupus Nephritis

Spain, United Kingdom, United States, Canada, Thailand, Germany, Italy, Japan, Serbia, Australia, Korea, Republic of, Mexico, Malaysia, Philippines, Poland, Portugal, Greece, Hong Kong, Czechia, France
Alkermes, Inc.

Completed

A Study of ALKS 9072 in Subjects With Chronic Stable Schizophrenia

Schizophrenia

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Study to Assess the Efficacy, Safety and Tolerability of MT- 8554 in Subjects With Painful Diabetic Peripheral Neuropathy

Painful Diabetic Peripheral Neuropathy

Germany, Hungary, Poland
CK Regeon Inc.

Completed

Safety, Tolerability, and Pharmacokinetic Evaluations of CKR-051 After Transdermal Administration in Healthy Male Subjects

Healthy

Korea, Republic of
Bioxodes S.A.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ir-CPI in Healthy Male Subjects

Healthy

Belgium
Pfizer

Completed

A Study To Assess The Safety Of PF-06342674 In Adults With Type 1 Diabetes

Diabetes Mellitus, Type 1

United States
Galapagos NV
Pharmaceutical Research Associates; SGS S.A.

Completed

A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG2451 in Healthy Female Subjects

Healthy

Belgium
University of Colorado, Boulder

Completed

Oral Trehalose Therapy to Reverse Arterial Aging in Middle-Aged and Older Adults

Vascular Aging

United States
Protalix

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid Levels

Gout

New Zealand
University of Sarajevo
Wellcome Trust; University of Dundee; General Hospital Prim. Dr. Abdulah Nakas

Completed

Interaction Between Omeprazole and Gliclazide in CYP2C19 Normal/ Ultrarapid Metabolisers (INTERGLIKOM)

Diabetes Mellitus, Type 2

Bosnia and Herzegovina
Receptor Life Sciences

Withdrawn

Safety, Tolerability, and Efficacy of RLS103 in Subjects With Acute Anxiety Within Social Anxiety Disorder (SAD)

Social Anxiety Disorder

United States

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