Search clinical trials for: Prostaglandin Antagonists

Total 32964 results

Millennium Pharmaceuticals, Inc.

Completed

Safety and Efficacy of TAK-385 for Patients With Localized Prostate Cancer

Prostate Cancer

United States, United Kingdom
European Organisation for Research and Treatment...

Withdrawn

TAK-700 in Castration Resistant Prostate Cancer

Prostate Cancer

Belgium
Royal College of Surgeons, Ireland
University College Dublin; University of Oxford; University of Liverpool; University...

Not yet recruiting

The RolE oF Androgen Excess in MUscle Energy MetaboLism in Women With PolyCystic Ovary Syndrome (REFUEL PCOS) Study 2 (REFUEL PCOS)

Polycystic Ovary Syndrome | Metabolic Disease | Androgen Excess

Ireland
Janssen Pharmaceutical K.K.

Recruiting

A Study of Macitentan in Japanese Pediatric Participants With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Japan
Assistance Publique - Hôpitaux de Paris
Janssen, LP

Recruiting

Initial Dual Oral Combination Therapy Versus Standard-of-care Initial Oral Monotherapy Prior to Balloon Pulmonary Angioplasty in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (IMPACT-CTEPH)

Chronic Disease | Inoperable Disease | Thromboembolic Pulmonary Hypertension

France
Actelion

Completed

A Study of Two Macitentan Pediatric Formulations in Healthy Adult Participants

Healthy

Belgium
Boston Children's Hospital

Terminated

Safety and Efficacy Trial of Danazol in Patients With Fanconi Anemia or Dyskeratosis Congenita

Fanconi Anemia | Dyskeratosis Congenita

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Withdrawn

Bicalutamide With or Without Enzastaurin in Treating Patients With Prostate Cancer

Prostate Cancer
Borstkanker Onderzoek Groep
Novartis Pharma B.V.; BOOG Study Center

Recruiting

SEQUence of Endocrine Therapy in Advanced Luminal Breast Cancer (SEQUEL-Breast) (SEQUEL-Breast)

Neoplasm, Breast | Congenital, Familial and Genetic Disorders

Netherlands
Dr. Reddy's Laboratories Limited

Completed

Bioavailability Study of Desloratadine 5 mg Tablet of Dr. Reddy's Under Fed Conditions

Fed

United States
Astellas Pharma Inc

Completed

Solifenacin as Add-on Therapy for Overactive Bladder Symptoms in Men Treated for Benign Prostatic Hyperplasia

Overactive Bladder | Benign Prostatic Hyperplasia | Benign Prostatic Hypertrophy

Japan
NeuroRx, Inc.
Prevail Infoworks, Inc

Completed

NRX-101 for Bipolar Depression With Subacute Suicidal Ideation

Bipolar Depression | Suicidal Ideation and Behavior

United States
Sunovion

Completed

Lurasidone HCl - A Long Term Phase 3 Study of Patients With Chronic Schizophrenia (PEARL 3 Ext)

Chronic Schizophrenia

United States, Colombia, India, Ukraine, Russian Federation, Romania
Sunovion

Completed

Safety and Tolerability Study of Drug to Treat Schizophrenia

Schizophrenia

United States
Organon and Co

Completed

Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Eczema/Dermatitis and Dermal Pruritus (MK-4117-202)

Dermatitis | Eczema | Dermal Pruritus
Translational Oncology Research International
University of California, Los Angeles; AstraZeneca; Genentech, Inc.

Terminated

Fulvestrant and/or Trastuzumab as First-Line Therapy in Treating Postmenopausal Women With Stage IV Breast Cancer

Breast Cancer

United States
Assiut University

Unknown

Non Invasive Assessment of Heart Failure

Heart Failure
AstraZeneca

Completed

Phase I, Dose Study to Look at the Safety and Pharmacokinetics of AZD8835 in Patients With Advanced Solid Tumours

Advanced Solid Malignancies | Breast Cancer - ER+, HER2 - | Breast Cancer - ER+, HER2-, PIK3CA Gene Mutation

United States, United Kingdom
UCB Pharma

Completed

CUTE (Chronic Urticaria Treatment Evaluation)

Chronic Idiopathic Urticaria

France, Germany, United Kingdom, Belgium, Spain, Malaysia, Romania, South Africa, Italy
Kinnov Therapeutics
ECSOR

Completed

Clinical Outcome of a Patented Pharmaceutical Composition (KT-110) to Treat Alcohol Use Disorder While Avoiding Major Side Effects (COCKTAIL)

Alcohol Use Disorder

France
Indira Gandhi Medical College, Shimla

Completed

Montelukast and Fexofenadine Versus Montelukast and Levocetrizine Combination in Allergic Rhinitis

Allergic Rhinitis
Sanofi

Completed

Long-Term Safety Performance of Fexofenadine in Asthma

Asthma

United States
Boehringer Ingelheim
HealthCore-NERI

Completed

Assessment In a Real World Setting of the Effect of Inhaled Steroid-based Triple Therapy Versus the Combination of Tiotropium and Olodaterol on Reducing Chronic Obstructive Pulmonary Disease (COPD) Exacerbations [AIRWISE]

Pulmonary Disease, Chronic Obstructive

United States
Mara Chambers
Novartis

Completed

Study of Combined Fulvestrant and Everolimus in Advanced/Metastatic Breast Cancer After Aromatase Inhibitor Failure (BRE-43)

Breast Cancer

United States
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study for Desloratadine OD Tablets 5 mg Under Fasting Condition

Healthy

United States
Hanmi Pharmaceutical Company Limited

Completed

PK and Safety Study of HCP1102, HGP0813 and HGP1408

Healthy

Korea, Republic of
Chulalongkorn University

Not yet recruiting

Pharmacokinetics of Drospirenone Only Pills: A Pre- and Post-Bariatric Surgery Study

Contraception

Thailand
Alessa Therapeutics Inc.
National Cancer Institute (NCI)

Recruiting

Bicalutamide Implants (Biolen) With Radiation Therapy in Patients With Localized Prostate Cancer (BiolenRT)

Prostate Adenocarcinoma

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology; Southwest Oncology Group

Completed

Radiation Therapy With or Without Bicalutamide for Recurrent pT3N0 Prostate Cancer After Radical Prostatectomy

Prostate Cancer

United States, Canada
University of Pennsylvania
Brigham and Women's Hospital; University of Washington; Vanderbilt University; George...

Completed

Safety and Cardiovascular Efficacy of Spironolactone in Dialysis-Dependent ESRD Trial (SPin-D)

End-Stage Renal Disease

United States
University of Pavia

Completed

Canrenone Effects on Cardiovascular Mortality in Patients With Congestive Heart Failure (the Coffee-it Study) (THE COFFEE-IT)

Cardiac Heart Failure Patients

Italy
Actelion

Completed

Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension (SERAPHIN)

Pulmonary Arterial Hypertension

United States, United Kingdom, Belarus, Argentina, Australia, Austria, Belgium, Bulgaria, Canada, Chile, China, Colombia, Croatia, France, Germany, Hong Kong, Hungary, India, Israel, Italy, Malaysia, Mexico, Netherlands, Norway, Peru, Poland and more
Jinling Hospital, China
Wenzhou Medical University; Jiangsu Province Hospital of Traditional Chinese... and other collaborators

Unknown

AR-inhibitor Bicalutamide in Treating Patients With TNBC (Arbre)

Breast Neoplasms
University of Toledo Health Science Campus

Completed

Hemodynamic Effects of Spironolactone in Patients With Heart Failure

Congestive Heart Failure

United States
UPECLIN HC FM Botucatu Unesp

Unknown

Effects of Spironolactone in Dialysis

Renal Failure

Brazil
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study of Spironolactone 25 mg, 50 mg and 100 mg Tablets

Healthy

India
AstraZeneca

Withdrawn

CMAB vs IMAB in Metastatic Prostate Cancer

Metastatic Prostate Cancer

Mexico
Sermonix Pharmaceuticals Inc.

Recruiting

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation (ELAINEIII)

Metastatic Breast Cancer

United States, France, Belgium, Spain, Israel, Taiwan, United Kingdom, Korea, Republic of, Italy, Australia, Germany, Canada, Czechia, Hungary, Poland, Romania, Singapore, Turkey
Organon and Co

Completed

Safety of Desloratadine in Children With Allergy Sensitivity and Chronic Hives, Who Are Poor Metabolizers of Desloratadine (Study P02994)

Chronic Idiopathic Urticaria | Atopy
Dr. Reddy's Laboratories Limited

Completed

Bioavailability Study of Dr. Reddy's Desloratadine Tablets, 5 mg Under Fasting Conditions.

Fasting

United States
Shin-hwar Wu

Completed

Individualized Dosing Schedule of Inhaled Bronchodilator for Endotracheally Intubated COPD Patients

Chronic Obstructive Pulmonary Disease

China
Bukwang Pharmaceutical

Completed

A 6-week Study to Evaluate the Efficacy and Safety of Lurasidone HCL in Acutely Psychotic Patients With Schizophrenia

Schizophrenia

Korea, Republic of
University Hospital, Caen

Not yet recruiting

SPironolactONe for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation (SPONSoR)

Atrial Fibrillation Recurrent
Actelion

Completed

Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension (MERIT-2)

Chronic Thromboembolic Pulmonary Hypertension

Poland, Ukraine, United Kingdom, China, Russian Federation, Belgium, Germany, Thailand, Hungary, France, Lithuania, Czechia, Mexico, Switzerland, Turkey
Actelion

Completed

A Study of Two Macitentan Formulations in Healthy Adult Participants

Healthy

Belgium
Assistance Publique - Hôpitaux de Paris

Completed

Aldosterone Blockade Early After Acute Myocardial Infarction (ALBATROSS)

Myocardial Infarction

France
Karolinska University Hospital

Completed

Clinical Trial to Study Quality of Life in Prostate Cancer Patients by Randomizing Anti-androgen Versus Total Androgen Blockage Prior to Curative Intended Radiation Therapy

Prostate Cancer
Actelion

Completed

Macitentan Use in an Idiopathic Pulmonary Fibrosis Clinical Study (MUSIC)

Idiopathic Pulmonary Fibrosis

United States, Israel, Spain, Australia, France, Canada, Turkey, Germany, Italy, South Africa, Slovenia, Sweden
Dialysis Outcomes Heart Failure Aldactone Study...

Completed

Effects of Spironolactone on Cardio- and Cerebrovascular Morbidity and Mortality in Hemodialysis Patients

End-stage Renal Failure

Japan
Wolfson Medical Center

Completed

Effect of Aldosterone Blockade on Arterial Compliance (RAAS LAEI SAEI)

Arterial Stiffness | Arterial Elasticity

Israel

Search clinical trials for: Prostaglandin Antagonists

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