Search clinical trials for: RO5503781 SDP

Total 2376 results

Hoffmann-La Roche

Completed

A First-In-Human Study of RO5503781 in Participants With Advanced Malignancies Except Leukemia

Neoplasms

France, Canada, Netherlands, Korea, Republic of, Australia
Hoffmann-La Roche

Completed

A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors

Solid Tumors

United States, Canada
Hoffmann-La Roche

Completed

A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)

Solid Tumors

Hungary
St. Jude Children's Research Hospital

Withdrawn

Trial of Idasanutlin and Selinexor Therapy for Children With Progressive/Relapsed AT/RT or Extra-CNS Malignant Rhabdoid Tumors

Rhabdoid Tumor | CNS Tumor | Atypical Teratoid/Rhabdoid Tumor | Atypical Teratoid/Rhabdoid Tumor of CNS

United States
Hoffmann-La Roche

Completed

A Study of RO5503781 as a Single Agent or in Combination With Cytarabine in Participants With Acute Myelogenous Leukemia

Myelogenous Leukemia, Acute

United States, Korea, Republic of, Australia, United Kingdom, Canada, France, Italy
Hoffmann-La Roche

Terminated

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Idasanutlin Monotherapy in Participants With Hydroxyurea-Resistant/Intolerant Polycythemia Vera

Polycythemia Vera

United States, Canada, Italy, Australia
Polish Mother Memorial Hospital Research Institute

Completed

The Impact of Positioning on Bottle-feeding in Preterm Infants. A Comparative Study PMMHHRI-2018/V/9-SZB

Bottle Feeding | Premature

Poland
Canadian Forces Health Services Centre Ottawa

Active, not recruiting

Psychedelic Therapy for Wellness Studies Retrospectively

Well Aging

Canada
National Cancer Institute (NCI)

Active, not recruiting

Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I)

Hematopoietic and Lymphoid Cell Neoplasm | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
Azienda Ospedaliera Città della Salute e della...

Completed

Comparison Between Two Strategies of Discharge Planning for the Reduction of Short Term Hospital Readmissions (PROMENADE)

Patient Discharge

Italy
Silk Technologies, Ltd.

Completed

Study to Evaluate the Safety and Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED) (SDP-4-CS201)

Dry Eye

United States
Hoffmann-La Roche

Terminated

A Study of Idasanutlin in Combination With Obinutuzumab in Relapsed/Refractory (R/R) Follicular Lymphoma (FL) and in Combination With Rituximab in R/R Diffuse Large B-Cell Lymphoma (DLBCL) Participants

Non-Hodgkin's Lymphoma

United States, Australia, Korea, Republic of, Germany, New Zealand
He Xia

Unknown

Weekly Cisplatin or Nedaplatin Concurrent With Intensity-modulated Radiation Therapy in Nasopharyngeal Carcinoma (NPC-RCT-WCRT)

Nasopharyngeal Carcinoma
Sun Yat-sen University
The First Affiliated Hospital of Guangdong Pharmaceutical University; Guangzhou... and other collaborators

Completed

Concurrent Chemoradiotherapy With Nedaplatin Versus Cisplatin in Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Silk Technologies, Ltd.

Completed

Study to Evaluate the Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED) (SDP-4-CS202)

Dry Eye

United States
Guang'anmen Hospital of China Academy of Chinese...
Ministry of Science and Technology of the People´s Republic of China

Completed

Efficacy and Safety Study of Electroacupuncture for Simple Female Stress Urinary incontinence-a Multicenter Trial

Urinary Stress Incontinence

China
The University of Texas Health Science Center at...
Alzheimer's Association; The Claude D. Pepper Older Americans Independence... and other collaborators

Completed

Stress-Busting Program and QoL, Bio-markers of Immunity/Stress and Cellular Aging

Stress, Psychological | Stress, Physiological | Telomere Shortening

United States
Shanghai Yueyang Integrated Medicine Hospital

Completed

Evaluation of Integrated Optimization Schemes for Female Stress Incontinence (EIOSFSI)

Stress Urinary Incontinence in Women

China
Jilin University

Unknown

Comparison of Different Surgical Treatments for Different Scales of Cubital Tunnel Syndrome

Cubital Tunnel Syndrome

China
The University of Hong Kong

Completed

Effect of Application Time of 38% Silver Diamine Fluoride Solution on Arresting Dental Caries in Preschool Childre

Early Childhood Caries

Hong Kong
Valeant Pharmaceuticals

Unknown

A Study Comparing the Efficacy and Safety of IDP-120 Gel in the Treatment of Acne Vulgaris

Acne Vulgaris
Sumitomo Pharma Co., Ltd.

Completed

Confirmatory Study of DSP-5423P in Patients With Schizophrenia

Schizophrenia

China, Japan, Korea, Republic of, Malaysia, Philippines, Russian Federation, Taiwan, Ukraine
Bausch Health Americas, Inc.

Completed

A Phase 2, Multicenter, Randomized, Double-Blind, Vehicle Controlled, Parallel-Group, Clinical Study in the Treatment of Acne Vulgaris

Acne Vulgaris

United States, Canada
The George Institute
Changhai Hospital; University of Calgary

Not yet recruiting

Third Enhanced Control of Hypertension and Thrombectomy Stroke Domain Within ACT-GLOBAL Adaptive Platform Trial (ENCHANTED3/MT)

Ischemic Stroke, Acute
University Hospital, Rouen
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Genetic Variants Associated With Adolescent Suicide Attempts (VGTSA)

Attempt Suicide

France
Dow Pharmaceutical Sciences

Unknown

A Phase 2 Dose Ranging, Evaluator-Blinded Study to Evaluate the Safety of Topical IDP-118 (IDP-118)

Plaque Psoriasis

United States
iScience Interventional Corporation

Completed

Surgical Treatment of Refractory Open Angle Glaucoma

Open Angle Glaucoma

United States
Johns Hopkins University
National Institute on Aging (NIA)

Recruiting

HEARS-SLP: Providing SLP-Delivered Hearing Health Care to Individuals With Cognitive Impairment

Cognitive Impairment | Dementia | Hearing Loss

United States
IlDong Pharmaceutical Co Ltd

Completed

A Phase I Study of IDP-73152 Mesylate in Health Male Volunteer (PDF inhibitor)

Healthy

Korea, Republic of
Sun Pharmaceutical Industries Limited

Withdrawn

A Comparative Study of SPARC's SDP-133 Once Daily and Lumigan in Subjects With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma
Polish Mother Memorial Hospital Research Institute

Completed

A Comparison Study of Feeding Prematures in the Side-lying Position on the Right and Left Side - a Pilot Study.

Bottle Feeding | Premature

Poland
Klinikum St. Georg gGmbH

Completed

Trigeminus-evoked Somatosensory Potentials in Patients Undergoing Carotid Surgery (TRISEP)

Carotid Surgery

Germany
Sumitomo Pharma America, Inc.

Completed

A Clinical Trial That Will Study the Efficacy and Safety of an Investigational Drug in Acutely Psychotic People With Schizophrenia

Schizophrenia

United States, Serbia, Croatia, Bulgaria, Latvia, Russian Federation, Ukraine
Bausch Health Americas, Inc.

Completed

Efficacy and Safety of IDP-124 Lotion for the Treatment of Moderate to Severe Atopic Dermatitis in Pediatric and Adult Subjects

Atopic Dermatitis

United States
Mondelēz International, Inc.
University of Sydney

Completed

Determination of the Postprandial Responses to Two Cereal Foods Differing by Their SDS Content and GI Consumed Alone.

Metabolism and Nutrition Disorders

Australia
Valeant Pharmaceuticals

Unknown

A Study Comparing the Efficacy and Safety of IDP-121 and IDP-121 Vehicle Lotion in the Treatment of Acne Vulgaris

Acne Vulgaris
Sunovion

Completed

Study Assessing the Safety, Tolerability, and Pharmacokinetics of SEP-363856 in Male and Female Subjects With Schizophrenia (SEP-363856)

Schizophrenia

United States
Hoffmann-La Roche

Terminated

A Study of Taselisib + Fulvestrant Versus Placebo + Fulvestrant in Participants With Advanced or Metastatic Breast Cancer Who Have Disease Recurrence or Progression During or After Aromatase Inhibitor Therapy (SANDPIPER)

Breast Cancer

Italy, United States, Korea, Republic of, Canada, Czechia, Spain, Australia, Bulgaria, China, Finland, France, Greece, Poland, Portugal, Taiwan, Thailand, Turkey, Colombia, Bosnia and Herzegovina, Mexico, Peru, Romania, Russian Federation and more
VisCardia Inc.
Clinical Accelerator Ltd.

Active, not recruiting

RECOVER-HF Pilot Study of SDS in Heart Failure

Heart Failure With Reduced Ejection Fraction

Georgia, Uzbekistan
Sumitomo Pharma America, Inc.

Completed

A Clinical Trial to Study the Efficacy and Safety of an Investigational Drug in Acutely Psychotic People With Schizophrenia

Schizophrenia

United States, Serbia, Colombia, Bulgaria, Russian Federation, Ukraine
Bausch Health Americas, Inc.

Completed

Efficacy and Safety of IDP-124 Lotion for the Treatment of Moderate to Severe Atopic Dermatitis in Pediatric and Adult Subjects (301)

Atopic Dermatitis

United States
Bausch Health Americas, Inc.

Completed

Study Comparing the Safety and Efficacy of IDP-120 Gel and IDP-120 Vehicle Gel in the Treatment of Acne Vulgaris

Acne Vulgaris

United States, Canada
Bausch Health Americas, Inc.

Completed

Study Comparing the Safety and Efficacy of IDP-120 Gel and IDP-120 Vehicle Gel in the Treatment of Acne Vulgaris

Acne Vulgaris

United States, Canada
Bausch Health Americas, Inc.

Completed

Clinical Study Comparing the Efficacy and Safety of IDP-126 Gel in the Treatment of Acne Vulgaris

Acne Vulgaris

United States, Canada
Bausch Health Americas, Inc.

Completed

Clinical Study Comparing the Efficacy and Safety of IDP-126 Gel in the Treatment of Acne Vulgaris

Acne Vulgaris

United States, Canada
Valeant Pharmaceuticals

Unknown

A Study Comparing the Efficacy and Safety of IDP-121 and IDP-121 Vehicle Lotion in the Treatment of Acne Vulgaris

Acne Vulgaris
Hacettepe University

Completed

Management of Molar Incisor Hypomineralization With Silver Diamine Fluoride

Dental Caries | Molar Incisor Hypomineralization

Turkey
Enanta Pharmaceuticals, Inc

Terminated

A Randomized, Double-blind Study to Assess the Safety and Efficacy of EDP-305 in Subjects With Liver-biopsy Proven NASH

Non-Alcoholic Steatohepatitis

United States, Canada, Puerto Rico, United Kingdom, Argentina, Germany
Bausch Health Americas, Inc.

Completed

A Phase 3, Vehicle-controlled Efficacy and Safety Study of IDP-123 Lotion in the Treatment of Acne Vulgaris (301)

Acne Vulgaris

United States, Canada
Bausch Health Americas, Inc.

Completed

A Phase 3, Vehicle-controlled Efficacy and Safety Study of IDP-123 Lotion in the Treatment of Acne Vulgaris (302)

Acne Vulgaris

United States, Canada

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