Search clinical trials for: RPL554 matched placebo

Total 53893 results

Lohocla Research Corporation
National Institute on Drug Abuse (NIDA)

Recruiting

A Study to Test the Effects of Kindolor at Different Doses in Healthy Adults

Chronic Pain

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis and F/MF Genotypes

Cystic Fibrosis

Canada, France, Germany, United Kingdom, Israel, Australia, Spain, Netherlands, Denmark, Switzerland
Novartis Pharmaceuticals

Completed

Extension Study to Assess Long Term Safety, Tolerability, and Efficacy of Valsartan and Enalapril Combined and Alone in Children With Hypertension

Hypertension

United States, Belgium, France, Germany, Hungary, India, Italy, Poland, Turkey
Vertex Pharmaceuticals Incorporated

Completed

A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation

Cystic Fibrosis

United States, United Kingdom, Belgium, Netherlands, France, Denmark, Israel, New Zealand, Australia, Ireland, Sweden, Canada, Germany, Poland, Switzerland, Italy, Austria, Hungary, Greece, Norway
University of Minnesota
American Diabetes Association

Completed

Bariatric Surgery And Adipose Inflammation Dysfunction and Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus | Insulin Resistance

United States
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy

Acute Pain

United States
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis Subjects Without an F508del Mutation

Cystic Fibrosis

Spain, Belgium, Netherlands, France, Canada, Germany, Sweden, Italy, Czechia, Switzerland, Portugal, Austria, Hungary, Norway, Poland
University of Alabama at Birmingham
Merck Sharp & Dohme LLC

Completed

Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries

Postpartum Sepsis | Postpartum Endometritis | Postpartum Fever

Cameroon
University of East Anglia

Terminated

Metabolism of Anthocyanins and Heart Health (AMP)

Healthy

United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

Cystic Fibrosis

United States, Spain, United Kingdom, New Zealand, Israel, Australia, Ireland, Germany, Sweden, Czechia, Portugal, Hungary
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

A Study of TQA3526 in the Treatment of Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis

China
Xencor, Inc.
PPD; ICON plc

Completed

A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
AstraZeneca
Quintiles, Inc.

Completed

This is a Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of AZD9742 After Single IV Doses in Healthy Subjects

Healthy

United States
AstraZeneca

Completed

The Effects AZD8529 on Cognition and Negative Symptoms in Schizophrenics

Schizophrenia

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Assessment of Any Potential Retinal Effects of Tafenoquine (TQ)

Malaria, Vivax

United States
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of Efficacy and Safety of VX-548 for Acute Pain After an Abdominoplasty

Acute Pain

United States
Energenesis Biomedical Co., Ltd.

Recruiting

A Study to Evaluate ENERGI-F703 GEL in Venous Leg Ulcer

Venous Leg Ulcer

Taiwan
University of Louisville

Completed

The Effect of Platform-Matching Versus Platform-Switching Dental Implants on Peri-implant Hard and Soft Tissue Healing

Missing Tooth

United States
The Alfred

Unknown

CPET in CF Patients With One G551D Mutation Taking VX770

Cystic Fibrosis

Australia
University of California, Los Angeles

Unknown

A Study Comparing Long-acting Methylphenidate (ConcertaTM) vs. Placebo in the Treatment of Memory Loss Due to HIV

HIV Dementia

United States
University of South Alabama
Takeda; Sucampo Pharmaceuticals, Inc.

Terminated

Comparison of Lubiprostone and Placebo for the Relief of Constipation From Constipating Medications

Constipation

United States
HighTide Biopharma Pty Ltd

Completed

A Multiple Ascending Dose Study of HTD1801 in Adults With Hypercholesterolemia

Hypercholesterolemia

Australia
AstraZeneca

Active, not recruiting

Efficacy and Safety Study of Benralizumab in Patient With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps (ORCHID) (ORCHID)

Nasal Polyposis

United States, Italy, Belgium, Taiwan, Thailand, Vietnam, France, Hungary, China, Japan, Australia, Argentina, Poland, Russian Federation, Turkey, Bulgaria, Chile
Joshua M Hare
The Emmes Company, LLC; The Lester And Sue Smith Foundation

Terminated

Allogeneic Human Cells (hMSC)in Patients With Idiopathic Pulmonary Fibrosis Via Intravenous Delivery (AETHER) (AETHER)

Idiopathic Pulmonary Fibrosis (IPF)

United States
Brown University

Completed

Effects of Ghrelin on Alcohol Cue Reactivity and Craving

Alcoholism

United States
Penn State University
Cotton Incorporated

Not yet recruiting

The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health

Cardiovascular Diseases
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Effect of Clonazepam on Cannabis Withdrawal and Relapse in Treatment-seeking Patients

Cannabis Use Disorder

United States
Novaremed Ltd.

Completed

Effect of NRD135S.E1 in Peripheral Neuropathic Pain in Diabetic Patients

Diabetic Peripheral Neuropathic Pain

Israel
Eli Lilly and Company

Active, not recruiting

A Study in Recurrent Glioblastoma (GB)

Glioblastoma

United States, Germany, Spain, Belgium, Italy, Australia, Canada, France, Poland
Montefiore Medical Center

Recruiting

Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Prader-Willi Syndrome

Hyperphagia | Prader-Willi Syndrome

United States
Sage Therapeutics
Biogen

Active, not recruiting

Study to Evaluate SAGE-324 in Participants With Essential Tremor

Essential Tremor

United States
Montefiore Medical Center
Foundation for Prader-Willi Research

Completed

Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome (OXT-PWS)

Hyperphagia | Prader-Willi Syndrome

United States
University of California, Los Angeles
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Amygdala Neurosciences

Withdrawn

Development of a Selective ALDH2 Inhibitor to Treat AUD

Alcohol Use Disorder

United States
Regeneron Pharmaceuticals
Sanofi

Completed

Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

Hypercholesterolemia | Heterozygous Familial Hypercholesterolemia

United States, Canada
SIGA Technologies
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I, Escalating, Multiple-Dose, ST-246 Safety, Tolerability and Pharmacokinetics 21-Day Trial in Healthy Volunteers (SIGA-246-002)

Healthy

United States
University College Dublin

Completed

Dipeptidyl Peptidase-4 Inhibition in Psoriasis Patients With Diabetes (DIP): A Randomized Clinical Trial. (DIP)

Type 2 Diabetes Mellitus | Psoriasis

Ireland
GlaxoSmithKline

Recruiting

Study of GSK3965193 in Healthy Participants and Participants Living With Chronic Hepatitis B Infection

Hepatitis B

United Kingdom
GlaxoSmithKline

Completed

A Clinical Study to Assess Single and Repeat Doses of a New Medication (GSK933776) in Patients With Alzheimer's Disease

Alzheimer's Disease

Australia, Sweden, Norway
Nordic Society of Gynaecological Oncology - Clinical...
Institute of Cancer Research, United Kingdom; Belgian Gynaecological Oncology... and other collaborators

Withdrawn

Rucaparib Maintenance Therapy in Advanced Cervical Cancer (MaRuC)

Cervical Cancer

Denmark
PegBio Co., Ltd.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of PB-201 in Type 2 Diabetic Mellitus Patients With Poor Glycemic Control Via Metformin Hydrochloride Monotherapy

Type 2 Diabetes Mellitus

China
424 General Military Hospital
Aristotle University Of Thessaloniki

Recruiting

Nitrate Use to Obtain Radial Spasm Embarrassment (NURSE - TTS Trial) (NURSE-TTS)

Radial Artery Spasm

Greece
University of Haifa

Recruiting

Efficacy of Reboxetine and Methylphenidate Treatment on Attentional, Sensory and Emotional Dysregulation in Adults With PTSD

Posttraumatic Stress Disorder

Israel
University of California, San Francisco

Completed

Characterizing the Synergistic Effects of Physical and Cognitive Training on Attention and Working Memory (BBT)

Healthy Adults

United States
Wake Forest University Health Sciences

Recruiting

Immersive Healing: The Therapeutic Potential of Virtual Reality

Phantom Limb Pain (PLP)

United States
CymaBay Therapeutics, Inc.

Completed

Study Investigating the Safety, Tolerability, and PK, PD, of CB-0406

Healthy Volunteers

Australia
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Selonsertib, Firsocostat, Cilofexor, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (ATLAS)

Nonalcoholic Steatohepatitis

Hong Kong, United States, Australia, Puerto Rico, New Zealand, Canada
Hoffmann-La Roche

Active, not recruiting

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer

United States, Italy, Korea, Republic of, Canada, Germany, United Kingdom, Australia, Belgium, Brazil, China, Denmark, France, Hong Kong, Portugal, Spain, Taiwan, Turkey, Japan, Argentina, Mexico, Israel, Poland, Russian Federation, Peru and more
Albert Einstein College of Medicine
The Humsafar Trust

Active, not recruiting

CHALO! 2.0: A Mobile Technology Based Intervention to Accelerate HIV Testing and Linkage to Preventive Treatment.

Hiv

India
Eisai Inc.
Quintiles, Inc.

Completed

A Study Comparing the Combination of the Best Supportive Care Plus E7080 Versus Best Supportive Care Alone, in Patients With Advanced Lung Cancer or Lung Cancer That Has Spread, Who Have Been Previously Treated, Unsuccessfully, With at Least 2 Different Treatments

Non-Small Cell Lung Cancer

Belgium, Korea, Republic of, Italy, United States, Hungary, United Kingdom, Czechia
Beth Israel Deaconess Medical Center
Johns Hopkins University; University of Maryland; Columbia University; Emory University and other collaborators

Completed

Progesterone vs Placebo Therapy for Women With Epilepsy

Epilepsy

United States, Canada

Search clinical trials for: RPL554 matched placebo

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