Search clinical trials for: Saizen®

Total 14097 results

Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Completed

Growth Hormone in Neuroendocrine Dysfunction With Severe Fibromyalgia Syndrome

Fibromyalgia

Spain
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

Saizen in Intra-uterine Growth Retardation

Children Born With Serious Intra-uterine Growth Retardation
Merck KGaA, Darmstadt, Germany
Merck Serono S.A.S., an affiliate of Merck KGaA, Darmstadt, Germany

Completed

Optimization of the Dosage Regimen of Growth Hormone Therapy in Children Born Small for Gestational Age (SGA OPTIMIS)

Small Gestational Age (SGA)
Merck KGaA, Darmstadt, Germany

Completed

Saizen® E-Device User Trial

Growth Disorders
Merck KGaA, Darmstadt, Germany

Completed

A Multicentre, Randomised, Open-label, Controlled Study to Evaluate the Effects of Saizen® on Cardiac Function in Growth Hormone Deficient(GHD) Subjects During the Transition Phase From Childhood to Adulthood

Growth Hormone Deficiency | Dwarfism
Merck KGaA, Darmstadt, Germany

Completed

Growth Hormone Treatment for the Prevention of Short Stature in Young Girls With Turner Syndrome Before the Age of 4 Years

Turner's Syndrome

France
Merck KGaA, Darmstadt, Germany

Completed

A Phase 3 Study to Evaluate the Safety and Efficacy of Saizen® in Children With Idiopathic Short Stature (ISS)

Idiopathic Short Stature

Korea, Republic of
EMD Serono

Terminated

Saizen® Solution for Injection Adult Growth Hormone Deficiency (GHD) Immunogenicity Study

Growth Hormone Deficiency (GHD)

United States
Merck KGaA, Darmstadt, Germany

Completed

An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD)

Adult Growth Hormone Deficiency

United Kingdom, Germany, Australia, Sweden
Merck KGaA, Darmstadt, Germany
Merck Serono S.A.S, France

Completed

A Pharmaco-epidemiological Study of Short Patients Born Small for Gestational Age (SGA), Treated With Saizen® (Recombinant Somatropin) (SEPAGE)

Infant, Small for Gestational Age

France
Seoul National University Hospital

Completed

GlideScope®Video Laryngoscope for Difficult Intubation: Implication of the Size of Blade

Intubation; Difficult
Merck KGaA, Darmstadt, Germany

Completed

Predictive Markers in Growth Hormone Deficiency (GHD) and Turner Syndrome (TS) Children Treated With SAIZEN®

Growth Hormone Deficiency | Turner Syndrome

Argentina, Australia, Austria, Canada, France, Germany, Italy, Norway, Russian Federation, Singapore, Spain, Sweden, United Kingdom
Deutsches Herzzentrum Muenchen

Recruiting

PROTECT TAVI - Prospective Randomized Outcome Study in TAVI Patients Undergoing Periprocedural Embolic Cerebral Protection With the Sentinel™ Device (PROTECT)

Cerebral Embolization During TAVI Using Balloon-expandable vs. Self-expandable Valves

Germany
Merck KGaA, Darmstadt, Germany
Merck Serono Limited, UK

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in the UK (ECOS UK)

Growth Disorders

United Kingdom
Merck KGaA, Darmstadt, Germany
Merck S.A. Columbia

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Columbia (ECOS COL)

Growth Disorders

Colombia
Merck KGaA, Darmstadt, Germany
Merck Gesellschaft mbH, Austria

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Austria (ECOS AUT)

Growth Disorders

Austria
Merck KGaA, Darmstadt, Germany
EMD Serono, a division of EMD Inc., Canada

Completed

A Canadian, Multi-centre, Observational Registry to Study Adherence and Long Term Outcomes of Therapy in Pediatric Subjects Using SAIZEN® Via Easypod™ Auto-injector for Growth Hormone Treatment (ECOS CAN)

Growth Disorders

Canada
Federico II University

Completed

Growth Hormone Deficiency in Chronic Heart Failure: A Preliminary Trial

Heart Failure | Ischemic Heart Disease | Growth Hormone Deficiency
Merck KGaA, Darmstadt, Germany
Merck Serono S.A.S, France

Completed

Efficacy and Safety Evaluation of Recombinant Human Growth Hormone (r-hGH), Saizen®, on a Population of Children With Hypochondroplasia, Treated at Least 3 Years or Until Near Final Height, When Applicable, in Comparison With a Historic Cohort of Non-treated Children

Hypochondroplasia

France
Clinique Ovo
EMD Serono

Completed

Adjuvant Growth Therapy in in Vitro Fertilization

Infertility

Canada
Merck KGaA, Darmstadt, Germany
Merck A.E., Greece

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Greece (ECOS GRE)

Growth Disorders

Greece
Groupe Hospitalier Paris Saint Joseph

Completed

Kinetics of Circulating Tumoral Cells in Bronchial Primitive Cancer

Bronchial Cancer

France
Federico II University
Agenzia Italiana del Farmaco; Istituto Biostrutture e Immagini, CNR Naples

Completed

Growth Hormone in Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Italy
Pacific Centre for Reproductive Medicine
EMD Serono

Terminated

Growth Hormone in Poor Responders to IVF Trial

Infertility

Canada
EMD Serono

Completed

r-hGH Liquid Multidose Versus Freeze-dried Multidose Bioequivalence Trial

Growth Hormone Deficiency | Growth Failure

Germany
Technical University of Munich

Unknown

Efficacy and Safety of Cold Snare Polypectomy (CSP) of Intermediate Sized Colorectal Polyps 10-15 mm (COLDSNAP-1)

Colorectal Adenoma | Colorectal Polyp

Germany
Edwards Lifesciences

Recruiting

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

Pulmonary Valve Insufficiency | Complex Congenital Heart Defect | Dysfunctional RVOT Conduit | Pulmonary Valve Degeneration

United States
Edwards Lifesciences

Active, not recruiting

EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis (EARLY TAVR)

Heart Diseases | Aortic Stenosis, Severe

United States, Canada
Edwards Lifesciences

Recruiting

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR (PROGRESS)

Aortic Valve Stenosis | Aortic Stenosis, Calcific

United States, Switzerland, Australia, Japan, Canada, Netherlands
Federico II University

Completed

Replacement GH Therapy After Bariatric Surgery in Patients With Very Severe Obesity (GH&LASGB)

Obesity | GHD

Italy
Edwards Lifesciences

Recruiting

PARTNER 3 Trial - Aortic Valve-in-Valve

Aortic Stenosis | Aortic Stenosis, Severe

United States, Canada
Edwards Lifesciences
American College of Cardiology

Completed

The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves - PII B (PARTNERII B)

Calcific Aortic Stenosis | Severe | Symptomatic

United States
Edwards Lifesciences

Completed

PARTNER II Trial: S3iCAP (PII S3i CAP)

Aortic Stenosis

United States, Canada
Edwards Lifesciences

Completed

PREVAIL-20J - Transfemoral Placement of 20mm Aortic Balloon Expandable Transcatheter Valve Trial (PREVAIL-20J)

Aortic Valve Stenosis

Japan
University of Minnesota

Completed

Portion Size Effects on Body Weight:Free Living Setting

Portion Sizes

United States
Institut für Pharmakologie und Präventive Medizin
Estimate, GmbH

Completed

Pulmonic SAPIEN XT THV (Pulmonic XT)

Pulmonary Valve Malfunction

Belgium, Canada, Switzerland
Edwards Lifesciences

Active, not recruiting

The SAPIEN 3 Ultra System in Intermediate Risk Patients With Symptomatic, Severe Aortic Stenosis

Aortic Valve Stenosis

Canada, United Kingdom
LMU Klinikum

Completed

Everyday Practice With Transcatheter Aortic Valve Implantation (EVERY-TAVI)

Aortic Valve Stenosis

Germany
Catharina Ziekenhuis Eindhoven

Completed

Oropharyngeal Space in Videolaryngoscopy

Intubation Complication | Abrasion of Soft Palate

Netherlands
Institut für Pharmakologie und Präventive Medizin

Completed

Pulmonic SAPIEN S3™ THV Registry (PulmonicS3)

Pulmonary Valve Malfunction | Right Ventricular Outflow Tract (RVOT) Dysfunction

Switzerland, Germany, Canada
Edwards Lifesciences

Not yet recruiting

ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral

Mitral Regurgitation | Mitral Valve Disease | Mitral Stenosis
Changhai Hospital
Shanghai Children's Hospital; Xian Children's Hospital

Not yet recruiting

Mini-sized MCE for Detection of Small Bowel in Children Under the Age of 10 Years

Small Bowel Disease

China
Edwards Lifesciences

Recruiting

ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve

Aortic Stenosis, Severe

United States, Australia, New Zealand, Canada
Edwards Lifesciences

Recruiting

COMPASSION S3 Post-Approval Study

Pulmonary Valve Insufficiency | Complex Congenital Heart Defect | Dysfunctional RVOT Conduit | Pulmonary Valve Degeneration | Pulmonary Valve; Obstruction

United States
Edwards Lifesciences

Active, not recruiting

COMPASSION XT PAS - Post-approval Study of the SAPIEN XT THV in Patients With Pulmonary Valve Dysfunction

Heart Diseases | Cardiovascular Diseases | Congenital Abnormalities | Heart Defects, Congenital | Pulmonary Valve Insufficiency | Pulmonary Valve Stenosis

United States
University of Padova
Edwards Lifesciences; Azienda Ospedaliera di Padova; Ospedale San Bortolo di...

Suspended

Impact of SAVR and TAVR on Patient's Activity and Mobility (CAPABILITY)

Aortic Valve Stenosis

Italy
Changhai Hospital
Qilu Hospital of Shandong University

Completed

Mini-sized MCE for Better Examination of UGI and Small Bowel

Capsule Endoscopy

China
Claret Medical

Completed

Cerebral Protection in Transcatheter Aortic Valve Replacement

Severe Symptomatic Calcified Native Aortic Valve Stenosis

United States, Germany
Edwards Lifesciences

Recruiting

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Aortic Valve Stenosis | Aortic Valve Insufficiency

United States, Canada
Seung-Jung Park
CardioVascular Research Foundation, Korea

Withdrawn

TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis (TRANSIT)

Aortic Valve Stenosis

Korea, Republic of

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