Search clinical trials for: Sitagliptin/metformin

Total 2745 results

Case Comprehensive Cancer Center

Completed

Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer

Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage IV Pancreatic Cancer

United States
Sanofi

Completed

Efficacy and Safety of Lixisenatide Versus Insulin Glulisine on Top of Insulin Glargine With or Without Metformin in Type 2 Diabetic Patients (GetGoal-Duo-2)

Type 2 Diabetes

United States, Canada, Chile, Czech Republic, Estonia, France, Germany, Hungary, Italy, Latvia, Lithuania, Mexico, Poland, Romania, Russian Federation, Spain, Ukraine, United Kingdom
Samsung Medical Center

Completed

Effect of Evogliptin on Albuminuria in Patients With Type 2 Diabetes and Renal Insufficiency (DA1229)

Renal Insufficiency | Albuminuria | Type2 Diabetes Mellitus

Korea, Republic of
Boehringer Ingelheim

Completed

Randomized, Double-blind (db), Placebo-controlled 18 Week Study of Linagliptin (BI 1356) in Type 2 Diabetic Patients With Insufficient Glycaemic Control on a Sulfonylurea Drug

Diabetes Mellitus, Type 2

United States, Argentina, Hungary, India, Japan, Poland, Russian Federation
Boehringer Ingelheim

Completed

Safety and Efficacy in Type 2 Diabetic Patients With Severe Chronic Renal Impairment, 5 mg BI 1356 (Linagliptin) vs. Placebo, Insulin Background Inclusive

Diabetes Mellitus, Type 2

United States, Australia, Hong Kong, Israel, New Zealand, Ukraine
Ain Shams University

Not yet recruiting

Evaluation of the Effects of Diosmin/Hespiridin Combination on the Clinical Outcomes in Patients With Polycystic Ovary Syndrome

Poly Cystic Ovary Syndrome
Sanofi

Completed

iGlarLixi vs IDegAsp in Chinese Participants After OAD(s)

Type 2 Diabetes Mellitus

China
Eli Lilly and Company

Completed

A Study of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes Mellitus (AWARD-10)

Type 2 Diabetes Mellitus

Czechia, Hungary, United States, Mexico, Germany, Austria, Israel, Puerto Rico, Spain
Amgen

Completed

A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular Cancer

Advanced Hepatocellular Carcinoma | Inoperable Hepatocellular Carcinoma
Chinese Anti-Cancer Association

Completed

Urea Cream Treatment Sorafenib-Associated HSFR in HCC

Hepatocellular Carcinoma

China
Emory University
Bristol-Myers Squibb; National Cancer Institute (NCI); National Institutes of...

Active, not recruiting

Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

Colorectal Cancer Metastatic | Colorectal Adenocarcinoma | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Refractory Colorectal Carcinoma | Metastatic Microsatellite Stable Colorectal Carcinoma | Stage IVC Colorectal Cancer

United States
Xian-Jun Yu

Completed

Metformin Combined With Gemcitabine as Adjuvant Therapy for Pancreatic Cancer After Curative Resection

Stage IA Pancreatic Adenocarcinoma | Stage IB Pancreatic Adenocarcinoma | Stage IIA Pancreatic Adenocarcinoma | Stage IIB Pancreatic Adenocarcinoma

China
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Daiichi... and other collaborators

Completed

The Effect of Welchol on Glucose Metabolism in Type 2 Diabetics

Type 2 Diabetes

United States
McMaster University

Withdrawn

Oral Peri-operative TIming of Metformin (or) Salsalate to Improve Non-cardiac Surgery Glucose Control (OPTIM(i)SING)

Hyperglycemia | Diabetes Mellitus, Type 2 | Perioperative/Postoperative Complications
Medical University of South Carolina

Withdrawn

Study of Metformin Plus Oligomeric Procyanidin Complex for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients

Prostate Cancer

United States
AstraZeneca

Completed

Study of Multiple Doses of Saxagliptin (BMS-477118)

Type 2 Diabetes Mellitus
University of Padova

Completed

Rapid Effects Linagliptin on Monocyte Polarization and Endothelial Progenitor Cells in Type 2 Diabetes

Type 2 Diabetes | Chronic Renal Failure

Italy
Boehringer Ingelheim

Completed

Pharmacokinetics and Pharmacodynamics of BI 1356 in Subjects With Different Degrees of Liver Impairment as Compared to Healthy Subjects

Hepatic Insufficiency
Cardresearch

Recruiting

A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial (REVIVE)

Chronic Fatigue Syndrome | Long COVID-19 Syndrome

Brazil
Beijing Dongfang Biotech Co., Ltd.

Active, not recruiting

Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese Subjects

Diabetes Mellitus, Type 2 | Overweight

China
Novo Nordisk A/S

Completed

Research Study Comparing a New Medicine "Fast-acting Insulin Aspart" to Another Already Available Medicine "NovoRapid"/"NovoLog" in People With Type 2 Diabetes (onset 9)

Diabetes Mellitus, Type 2 | Diabetes

United States, Poland, Croatia, Italy, Russian Federation, Spain, Canada, Serbia, Slovakia, Germany, Greece, Korea, Republic of, Czechia, Puerto Rico, Bulgaria, Romania, Argentina, Ukraine
University of Nevada, Reno
Augusta University

Completed

Linagliptin and Mesenchymal Stem Cells: A Pilot Study

Schizophrenia

United States
Phoenix VA Health Care System
Bristol-Myers Squibb

Completed

Effects of Saxagliptin on Adipose Tissue Inflammation in Humans

Type 2 Diabetes Mellitus (T2DM)

United States
Boehringer Ingelheim
Eli Lilly and Company

Completed

Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Linagliptin Compared With the Free Combination of Empagliflozin Tablet and Linagliptin Tablet in Healthy Male and Female Subjects

Healthy

Germany
dr. DJ Mulder
Boehringer Ingelheim

Completed

Off taRget Effects of Linagliptin monothErapy on Arterial Stiffness in Early Diabetes (RELEASE)

Type 2 Diabetes Mellitus

Netherlands
The University of Texas Medical Branch, Galveston

Withdrawn

New Treatment for Donor Sites (Donors)

Burn
Thomas Jefferson University

Completed

A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective

Advanced Liver Cancer | Metastatic Hepatocellular Carcinoma

United States
Washington State University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters

Interaction | Endogenous Biomarkers

United States
Medical University of Graz

Completed

Effects of Linagliptin on Endothelial Function

Coronary Artery Disease | Type 2 Diabetes

Austria
National Taiwan University Hospital

Unknown

A One-year Randomized Controlled Trial Evaluating the Impact of Pioglitazone Versus Linagliptin on Bone Turnover Markers

Diabetes Mellitus | Osteoporosis
Boehringer Ingelheim

Completed

Bioavailability of Warfarin After Coadministration With Multiple Doses of BI 1356 Compared to the Bioavailability of Warfarin Alone in Healthy Male Volunteers

Healthy
Sanofi

Completed

GLP-1 Receptor Agonist Lixisenatide Versus Exenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin (GETGOAL-X)

Diabetes Mellitus, Type 2

United States, Brazil, Poland, Russian Federation, Germany, Italy, Netherlands, Spain, Sweden, Argentina, Denmark, Finland, Hungary, Norway, Colombia, Austria, Greece, Puerto Rico
Novartis Pharmaceuticals

Completed

Vildagliptin Compared to Gliclazide as Dual Therapy With Metformin in Muslim Patients With Type 2 Diabetes Fasting During Ramadan (STEADFAST)

Type 2 Diabetes Mellitus

Egypt, United Kingdom, Turkey, Lebanon, Russian Federation, Tunisia, Malaysia, Germany, Spain, Saudi Arabia, Denmark, Indonesia, Jordan, Kuwait, Singapore, United Arab Emirates
University of Malaya
Ministry of Health, Malaysia

Unknown

Pharmacometabolomics of Andrographis Paniculata And Metformin In Healthy Volunteers Under Fasting Condition

Pharmacokinetics | Molecular Mechanisms of Pharmacological Action

Malaysia
University of North Carolina, Chapel Hill
WakeMed Health and Hospitals

Completed

Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes (MIPOD)

Pregnancy | Non Insulin Dependent Diabetes

United States
Amgen

Completed

AMG 386, 20060159 Phase 2, RCC 1st Line in Combination With Sorafenib

Advanced Renal Cell Carcinoma
ikfe-CRO GmbH
Novartis Pharmaceuticals; IKFE Institute for Clinical Research and Development

Unknown

Effect of Adding Vildagliptin on Beta Cell Function and Cardiovascular Risk Markers in Patients With Moderate Metabolic Control During Metformin Monotherapy

Diabetes Mellitus Type II

Germany
Karolinska Institutet

Completed

Effects on Re-endothelialisation With Bydureon Treatment in Type 2 Diabetes Subjects (Rebuild)

Diabetes | Atherosclerosis | Restenosis

Sweden
Fondazione IRCCS Istituto Nazionale dei Tumori,...
University of Milan

Unknown

Efficacy of metfOrmin in PrevenTIng Glucocorticoid-induced Diabetes in Patients With Brain Metastases (OPTIMAL)

Melanoma | Breast Cancer | Lung Cancer | Brain Metastases

Italy
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Efficacy and Safety of Ipragliflozin in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin (IMPRESSION)

Type 2 Diabetes Mellitus

Russian Federation
Yuhan Corporation

Completed

Clinical Trial of YH14755 in Subjects With Dyslipidemia and Type II Diabetes

Dyslipidemia | Type II Diabetes

Korea, Republic of
Sheba Medical Center
European Union

Unknown

Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy (SMC 0712-13)

Brain Neoplasms

Israel
Sanofi

Withdrawn

Study of Rimonabant/Metformin Combinations to Investigate Diabetes (Blood Sugar) Control in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States
Sanofi

Completed

Efficacy and Safety of Insulin Glargine in Patients With Type 2 Diabetes With Inadequate Control on DPP-4 Inhibitor Therapy (TED)

Diabetes Mellitus, Type 2

Korea, Republic of
Janssen R&D Ireland

Completed

A Study to Explore Pharmacokinetic Interaction Between Rilpivirine and Metformin in Healthy Participants

Healthy Participants

United States
IWK Health Centre
Sunnybrook Health Sciences Centre; Canadian Institutes of Health Research (CIHR) and other collaborators

Recruiting

Selective Early Medical Treatment of Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot RCT (SMART-PDA)

Patent Ductus Arteriosus After Premature Birth

United States, Canada
Sheba Medical Center

Recruiting

Microbiome and Polycystic Ovaries

Polycystic Ovary Syndrome | Microbial Colonization

Israel
Alexion Pharmaceuticals, Inc.

Completed

A Study to Investigate the Potential Drug Interactions Between ALXN2080 and Rosuvastatin and Metformin in Healthy Adult Participants

Healthy

United Kingdom
Columbia University

Completed

Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer

Breast Cancer | Breast Tumors | Cancer of Breast

United States
LMC Diabetes & Endocrinology Ltd.

Completed

The Effect of Soliqua on Glucose Variability in Type 2 Patients Among South Asians (VARIATION 2 SA)

Diabetes Mellitus, Type 2

Canada

Search clinical trials for: Sitagliptin/metformin

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