Search clinical trials for: System off

Total 187876 results

Tehran University of Medical Sciences

Completed

Morphine Analgesia in Patients With Acute Appendicitis

Appendicitis

Iran, Islamic Republic of
Odense University Hospital

Completed

OXY-2: The Pharmacogenetics of Oxycodone Analgesia in Human Experimental Pain Models

Healthy

Denmark
Indiana University

Completed

Effect of Antibacterial Mouthwash on Muscle Function in Healthy Young Men and Women

Quadriceps Muscle

United States
Buckinghamshire Healthcare NHS Trust

Unknown

Eyegaze Systems for Spinal Cord Injury: A Feasibility Study

Spinal Cord Injury

United Kingdom
University of Saskatchewan
Saskatoon Health Region

Completed

Intraoperative Posterior Cruciate Ligament (Transcruciate) Injection After Total Knee Arthroplasty (TKA)

Arthroplasty, Replacement, Knee

Canada
University of Michigan

Completed

A Difference-In-Differences Analysis of New Persistent Opioid Use After Surgery

Opioid Use

United States
University Hospital, Basel, Switzerland

Completed

Pain Response to Cannabidiol in Opioid-induced Hyperalgesia, Acute Nociceptive Pain and Allodynia By Using a Model Mimicking Acute Pain in Healthy Adults (CANAB II)

Hyperalgesia | Allodynia | Opioid-induced Hyperalgesia | Acute Nociceptive Pain

Switzerland
Hospices Civils de Lyon

Completed

Local Analgesia Versus Local Peroperative Infiltration After Total Hip Replacement (ALRIAL)

Total Hip Replacement

France
University of California, San Diego
Cadence Pharmaceuticals

Withdrawn

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of the Relationship Between Intraoperative Intravenous Acetaminophen and Postoperative Opioid Avoidance for Ambulatory Surgical Procedures (Cadence)

Postoperative Pain | Intraoperative and Postoperative Opioid Requirements

United States
Pfizer

Completed

A Clinical Study To Characterize The Pharmacokinetics And The Effects Of Food On Oxycodone In Healthy Volunteers

Chronic Pain | Analgesia | Acute Pain | Opioid-related Disorders | Narcotic Abuse

United States
Jeju National University School of Medicine

Completed

Remifentanil and Nitroprusside for Controlled Hypotension

Hypotension, Controlled

Korea, Republic of
KK Women's and Children's Hospital

Active, not recruiting

Vital Signs-Integrated Patient-Assisted Intravenous Opioid Analgesia for Post Surgical Pain (VPIA)

Pain | Respiratory Depression

Singapore
KK Women's and Children's Hospital

Active, not recruiting

Vital-signs-integrated Patient-assisted Intravenous Opioid Analgesia (VPIAmorphine)

Respiratory Depression

Singapore
Pacira Pharmaceuticals, Inc

Completed

Safety, Efficacy, and Pharmacokinetics of SKY0402 Administered as a Nerve Block in Subjects Undergoing Bunionectomy

Postoperative Pain
Purdue Pharma LP

Completed

The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.

Osteoarthritis

United States
University Hospital, Antwerp

Completed

Continuous Versus Automated Bolus Infusion in Sciatic Nerve Catheters

Surgery | Hallux Valgus

Belgium
Icahn School of Medicine at Mount Sinai

Completed

Effect of Paracervical Block on Post Operative Pain in Laparoscopic Gynecologic Surgery

Postoperative Pain | Paracervical Block | Laparoscopic Gynecologic Surgery

United States
Johns Hopkins University

Completed

Fetal and Infant Effects of Maternal Buprenorphine Treatment

Neonatal Abstinence Syndrome

United States
University of Colorado, Denver

Terminated

Effectiveness of Continuous Femoral Nerve Block Versus Single Shot Femoral Nerve Block for Pain Control

Post-operative Pain

United States
Purdue Pharma LP

Completed

Buprenorphine Transdermal System (BTDS) in Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Beijing Pins Medical Co., Ltd

Unknown

Efficacy and Safety of DBS in Patients With Treatment-Resistant Depression

Treatment Resistant Depressive Disorder

China
US Department of Veterans Affairs

Completed

Effectiveness of the FairCare System for Patients With Advanced Illness

Neoplasm | Terminal Care

United States
The Plastic Surgery Foundation

Completed

A Trial of Skin Care Protocols for Facial Resurfacing (SPAR)

Facial Photo Damage | Periocular Fine Wrinkles | Perioral Fine Wrinkles

United States
United States Naval Medical Center, Portsmouth

Terminated

Continuous Infusion of Local Anesthetic for Optimal Post Operative Pain Control Following Hemorrhoidectomy

Hemorrhoids

United States
Federal University of São Paulo

Unknown

Methadone Associated With Morphine for Cancer Pain

Cancer

Brazil
PainReform LTD
Lotus Clinical Research, LLC

Recruiting

A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain

Bunion

United States
Xiaobo Yang, MD

Recruiting

The Effects of ECMO on the Pharmacokinetics of Hydromorphone

Extracorporeal Membrane Oxygenation

China
Healthpoint Hospital

Not yet recruiting

Ropivacaine Use in Interscalene Block; What is the Minimal Effective Analgesic Concentration (MEAC 90)

Postoperative Pain

United Arab Emirates
University of Alberta

Completed

Comparison of Short-term Sustained-release Opioid in Open Abdominal Urologic Surgeries

Pain, Acute | Opioid Use

Canada
Turku University Hospital

Active, not recruiting

Postoperative Pain Relief With Transversus Thoracis Muscle Plane Block After Cardiac Surgery (TTPcat)

Coronary Artery Disease | Pain, Postoperative | Heart Valve Diseases | Anesthesia, Local

Finland
HealthPartners Institute
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC; Geisinger Clinic and other collaborators

Completed

Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0)

Opioid-use Disorder

United States
Medical University of Graz

Completed

The Influence of Tramadol on Platelet Function

Drug Toxicity | Platelet Dysfunction | Clotting Disorder

Austria
Yanchao Yang

Completed

The Optimal Dosage of Ropivacaine for Arthroscopic Knee Surgery

Ropivacaine | Arthroscopic Knee Surgery | Combined Spinal Epidurai Anesthesia | ED50 | ED95

China
Kangbuk Samsung Hospital

Completed

Nefopam as a Multimodal Analgesia for Thoracic Surgery

Lung Cancer

Korea, Republic of
Centre Hospitalier Universitaire de Nice

Terminated

Efficacy of Ropivacaine Continuous Wound Instillation Versus Single Shot After Spine Fusion Surgery

Postoperative Pain

France
Thomas Jefferson University

Active, not recruiting

Ropivacaine Pharmacokinetics in ESP Blocks

Pain | Quality of Recovery | Local Anesthetic Systemic Toxicity

United States
Sisli Hamidiye Etfal Training and Research Hospital

Completed

Volume Dependent Effect of Pericapsular Nerve Block

Post Operative Pain | Femur Fracture

Turkey
Sahlgrenska University Hospital, Sweden

Completed

Oxycodone Concentration in the Blood After Oral Premedication

Oxycontin

Sweden
Benha University

Completed

Erector Spinae Plane Block Impact on Quality of Recovery After Lumbar Spinal Decompression (ESPB)

Postoperative Pain

Egypt
University of Rochester

Completed

Brain Effects of Opiate Agonist and Antagonist

Chronic Low-back Pain

United States
Zealand University Hospital

Completed

Continuous TQL Block for Elective Cesarean Section

Postoperative Pain | Anesthesia, Local

Denmark
Medical College of Wisconsin
Children's Hospital and Health System Foundation, Wisconsin

Completed

Parent/Nurse Controlled Analgesia in the Neonatal Intensive Care Unit (PNCA)

Abdominal Surgery | Thoracic Surgery

United States
University of Southern Denmark
Region of Southern Denmark; Danish Council for Independent Research; The Faculty...

Completed

Genetic Variation in Organic Cation Transport 1 (OCT1) and Its Significance for Morphine Pharmacokinetics

Morphine | Organic Cation Transporter 1

Denmark
South Egypt Cancer Institute

Unknown

Aalgesic Efficacy of Erector -Spinae Technique With Levobupvicaine in Patients Undergoing Upper Abdominal Cancer Surgery

Erector Spinae Block Analgesia

Egypt
The Hospital for Sick Children

Withdrawn

Development of a Morphine Pharmacokinetic and Pharmacodynamic Model for the Neonatal Population

Pain | Drug Effect
Ataturk University

Completed

Transversus Thoracic Muscle Plane Block for Open Heart Surgery (TTMP)

Pain, Acute | Pain, Chest

Turkey
The Hospital for Sick Children

Completed

A Dose Finding Study of Remifentanil and Propofol for Lumbar Punctures in Children

Neoplasms | Hematologic Diseases

Canada
Mansoura University Hospital

Unknown

The Effect of Different Degree of Temperature on Levobupivacaine Spinal Anesthesia

Spinal Anesthetic Toxicity

Egypt
TriHealth Inc.

Completed

Effective Pain Management of Interscalene Blocks During Shoulder Surgery

Primary Osteoarthritis, Unspecified Shoulder

United States
National Institute on Drug Abuse (NIDA)

Completed

Pharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy Volunteers

Opioid-Related Disorders

United States

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