Search clinical trials for: TBP-PI-HBr

Total 3139 results

Spero Therapeutics
Covance

Completed

Study of the Absorption, Metabolism, and Excretion of [14C]-Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
Spero Therapeutics

Completed

A Study to Compare Two Bioanalytical Assays for Tebipenem

Healthy Volunteers

United States
Spero Therapeutics
Clinartis

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers

Healthy Volunteers

United States
Spero Therapeutics

Completed

Phase 1 Study of PK and Safety of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Subjects With Various Degrees Of Renal Function

Renal Impairment

United States
Spero Therapeutics

Completed

Bioequivalence Study Comparing Two Tablet Formulations of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Healthy Volunteers

United States
Spero Therapeutics
Celerion

Completed

A Single-Dose, Randomized, Placebo- and Active-Control, Four-Way, Cross-Over Study for the Evaluation of the Effect of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) on the QT/QTc Intervals in Adult Healthy Subjects

TQT Study

United States
Spero Therapeutics

Completed

Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (ADAPT-PO)

Acute Pyelonephritis | Complicated Urinary Tract Infection

Bulgaria, Georgia, United States, Czechia, Estonia, Hungary, Latvia, Moldova, Republic of, Poland, Romania, Russian Federation, Serbia, Slovakia, South Africa, Ukraine
Spero Therapeutics
Iqvia Pty Ltd

Completed

Effect of Tebipenem on Normal Human Intestinal Microbiota

Healthy Volunteers

Sweden
GlaxoSmithKline

Active, not recruiting

Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection

Hepatitis B, Chronic

Taiwan, Belgium, Thailand, Germany, Spain, Hong Kong, United Kingdom, France, Poland
Kyuzi Kamoi

Not yet recruiting

20 Years Results by HBP and DBP in Patients With Type 2 Diabetes Mellitus After Following-up

Diabetes Mellitus
Nagaoka Red Cross Hospital

Unknown

Long-term of 10 Years Results of a Prospective Longitudinal Study

Type 2 Diabetes Mellitus | Blood Pressure

Japan
Nagaoka Red Cross Hospital

Completed

A Cohort Study of Morning Home Blood Pressure Measurement in Type 2 Diabetic Patients

Hypertension | Type 2 Diabetes
Spero Therapeutics
GlaxoSmithKline

Recruiting

A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (PIVOT-PO)

Urinary Tract Infection | Acute Pyelonephritis

Moldova, Republic of, Georgia, United States, Serbia, Bulgaria, Romania, South Africa, Bosnia and Herzegovina, Croatia, Hungary, Poland, Slovakia
University Tunis El Manar

Unknown

Uterine Artery Pulsatility Index and Materno Fetal Outcomes (UADLAB)

Labor Complication

Tunisia
Peking University Third Hospital

Completed

Relationship Between Spinopelvic Parameters and Clinical Symptoms of Low-grade Lumbar Isthmic Spondylolisthesis

Isthmic Spondylolisthesis

China
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute; Dartmouth College; Advocates; Bay... and other collaborators

Recruiting

Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Covid19 | Intellectual Disability | Mental Illness | Developmental Disability | Axis I Diagnosis | Coronavirus

United States
Tobira Therapeutics, Inc.

Completed

A Proof of Concept Study to Evaluate the Antiviral Activity, Safety, and Pharmacokinetics of the CCR5 Antagonist TBR 652 in HIV 1-Infected, Antiretroviral Treatment-Experienced, CCR5 Antagonist-Naïve Patients

HIV-1 Infection
Spero Therapeutics

Completed

Study to Examine the Effect of Antacid and Omeprazole on the Single-Dose Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Healthy Volunteers

United States
Cellxpert Biotechnology Corp.
Medigen Biotechnology Corporation

Completed

Study of PI-88 in Patients With Advanced Melanoma

Melanoma

United States
Cellxpert Biotechnology Corp.
Medigen Biotechnology Corporation

Completed

PI-88 in Hepatocellular Carcinoma After Hepatectomy

Carcinoma, Hepatocellular

Taiwan
University of Michigan

Completed

The "Open Wound Bone Augmentation Concept" With Amnion-Chorion Membrane

Horizontal Ridge Deficiency

United States
Oslo University Hospital

Completed

A Multi-disciplinary Pain Intervention (MUD-PI) for Patients With Chronic Widespread Primary Pain (MUD-PI)

Chronic Pain, Widespread
Amgen

Completed

FIRST - Study of Pegfilgrastim Administered in the First and Subsequent Cycles of Myelosuppressive Chemotherapy

Neutropenia
Peptimmune

Completed

Safety Study of PI-0824 to Treat Pemphigus Vulgaris

Pemphigus Vulgaris

United States
Dayton Children's Hospital
United States Department of Defense; Kettering Health Network

Terminated

An Evaluation of Hyperbaric Treatments for Children With Cerebral Palsy

Cerebral Palsy | Cerebral Palsy, Spastic

United States
Assiut University

Recruiting

Perfusion Index in Assessment of Postoperative Pain in Children.

Postoperative Pain

Egypt
Life Molecular Imaging Ltd

Recruiting

[18F]PI-2620 Phase 3 Histopathological Study

Alzheimer Disease

United States
Life Molecular Imaging SA
Walter Reed National Military Medical Center

Active, not recruiting

Imaging [18F]PI-2620 and [18F]Florbetaben in Military Service Members With Blast Related Mild Traumatic Brain Injury

Mild Traumatic Brain Injury

United States
American Academy of Pediatrics
University of North Carolina, Chapel Hill; Thrasher Research Fund; RTI International and other collaborators

Completed

Newborn Heart Rate as a Catalyst for Improved Survival

Stillbirth | Neonatal Resuscitation | Neonatal Respiratory Depression | Neonatal Bradycardia

Congo, The Democratic Republic of the
Jae Seung Kim

Completed

Longitudinal Changes of [18F]PI-2620 Positron Emission Tomography in Subjects With Cognitively Normal, Mild Cognitive Impairment and Alzheimer's Disease

Alzheimer Disease | Mild Cognitive Impairment | Cognitively Normal

Korea, Republic of
Asan Medical Center
Korea Health Industry Development Institute

Completed

Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the Brain

Parkinson Disease | Alzheimer Disease | Healthy Volunteer | Frontotemporal Dementia

Korea, Republic of
Karolinska Institutet
Örebro University, Sweden

Completed

Predict Sepsis; the Predictive Value of Bedside Measures in the Ambulance

Sepsis | Sepsis Syndrome | Sepsis, Severe

Sweden
Minia University

Recruiting

AS-OCT Evaluation of Iridocorneal Angle of Patients of Angle Closure Glaucoma After Phacoemulsification

Glaucoma, Angle-Closure

Egypt
University of Pennsylvania
Yale University

Recruiting

Tau PET Imaging in Opioid Use Disorder

Opioid-Related Disorders

United States
Cellxpert Biotechnology Corp.
Medigen Biotechnology Corporation

Completed

PI-88 in Treating Patients With an Advanced Malignancy (Cancer) or Stage IV Melanoma

Unspecified Adult Solid Tumor, Protocol Specific | Melanoma (Skin)

Australia, United States
Macquarie University, Australia
Life Molecular Imaging GmbH; Omniscient Neurotechnology

Active, not recruiting

Tau And Connectomics In TES Study (TACIT)

Neurodegenerative Diseases | Cognitive Impairment | Head Injury Trauma | Chronic Traumatic Encephalopathy | Traumatic Encephalopathy

Australia
Chonbuk National University Hospital

Completed

Efficacy and Safety of Nokyong Mixture Extract(CME-PI) on Promotion of Immunity

Immunity

Korea, Republic of
Jens Eckstein
Preventicus GmbH

Completed

iPhone App Compared to Standard RR-measurement (iPARR)

Hypertension | Blood Pressure

Switzerland
Tiburio Therapeutics

Not yet recruiting

TBR-760 in Adult Patients With Non-Functioning Pituitary Adenomas

Non-Functional Pituitary Adenoma | Pituitary Tumor, Nonfunctioning
Kwong Wah Hospital

Completed

Effect of Smart Phone Based Telemonitoring on Blood Pressure Among Hypertensive Patients in Primary Care

Hypertension | Blood Pressure

Hong Kong
University of Colorado, Denver
American College of Radiology

Completed

Preclinical Imaging Biomarkers of Alzheimer's Disease Neuropathology in Young Adults With Youth-onset Diabetes: a Proof-of-concept Study

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Diabetes, Youth Onset

United States
Michael J. Fox Foundation for Parkinson's Research
Institute for Neurodegenerative Disorders

Completed

PPMI Tau PET Imaging

Parkinson Disease

United States
University of North Texas Health Science Center

Enrolling by invitation

Health and Aging Brain Study: Health Disparities Tau Positron Emission Tomography (PET) Scan Study

Alzheimer Disease

United States
Galenic Research Institute Ltd

Completed

Local mEHT + TCM Versus Intraperitoneal Chemoinfusion in Treatment of Malignant Ascites: Phase II RCT (OTMA-RII)

Peritoneal Neoplasms | Ascites | Yin Deficiency | Yang Deficiency

China
Amgen

Completed

Pegfilgrastim Given Same Day As or Day After Carboplatin and Docetaxel in Advanced Metastatic Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer | Lung Cancer
Genentech, Inc.

Completed

Evaluation Comparing Tau PET Radiotracers, [18F]GTP1 and [18F]PI-2620 or [18F]MK-6240 in Subjects With Normal Cognition or Prodromal to Moderate Alzheimer's Disease

Alzheimer Disease (AD)

United States
Progen Pharmaceuticals

Terminated

Phase III Study of PI-88 in Post-resection Hepatocellular Carcinoma (PATHWAY)

Cancer | Hepatocellular Carcinoma | Primary Liver Cancer | Liver Cancer | Hepatoma

Hong Kong, Singapore, United States, Australia, Canada, Italy, Malaysia, Spain, Taiwan, Thailand
Amgen

Completed

Evaluating Pegfilgrastim and a Multi-Day Topotecan Regimen in Subjects With Relapsed or Refractory Ovarian Cancer

Ovarian Cancer
Cellxpert Biotechnology Corp.
Medigen Biotechnology Corporation

Terminated

A Phase III PI-88 in the Adjuvant Treatment of Subjects With Hepatitis Virus Related HCC After Surgical Resection (PATRON)

Cancer | Hepatocellular Carcinoma | Liver Cancer

Korea, Republic of, Taiwan, Hong Kong, China
National Taiwan University Hospital

Unknown

Effects of RR and MT on Patient With Stroke

Cerebrovascular Accident

Taiwan

Search clinical trials for: TBP-PI-HBr

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