Search clinical trials for: TRUPULSE Generator

Total 2189 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Reducing Symptom Burden - Non Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer
Seoul National University Hospital
Seoul National University Bundang Hospital

Completed

Clinical Trial to Investigate the Effect on Corrected QT Interval Prolongation by Psychotropic Drugs

Healthy

Korea, Republic of
Novo Nordisk A/S

Active, not recruiting

A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in America

Obesity

United States
MODAG GmbH
Teva Pharmaceutical Industries, Ltd.; Quotient Sciences; Aptuit

Completed

A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)

Healthy Volunteers

United Kingdom
Duke University
Philip Morris USA, Inc.

Completed

Evaluation of a Tailored Smoking Cessation Treatment Algorithm Based on Initial Treatment Response and Genotype (ConNic3)

Smoking Cessation

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

VSV-hIFNbeta-NIS With or Without Ruxolitinib Phosphate in Treating Stage IV or Recurrent Endometrial Cancer

Recurrent Endometrial Adenocarcinoma | Recurrent Endometrial Carcinoma | Recurrent Endometrial Clear Cell Adenocarcinoma | Recurrent Endometrial Endometrioid Adenocarcinoma | Recurrent Endometrial Mixed Cell Adenocarcinoma | Recurrent Endometrial Serous Adenocarcinoma | Recurrent Endometrial Undifferentiated... and other conditions

United States
First Affiliated Hospital of Chongqing Medical...
Southwest Hospital, China; Central South University; The Second Affiliated Hospital... and other collaborators

Recruiting

Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD) (STAR-AD)

Depression | Sequestra

China
The Cleveland Clinic

Active, not recruiting

EMI-EHP Weight Management and Type 2 Diabetes Pragmatic Trial (EMPOWER-T2D)

Obesity | Type 2 Diabetes

United States
New York State Psychiatric Institute
National Institute of Mental Health (NIMH)

Completed

Treatment of Adolescent Suicide Attempters (TASA)

Depression | Suicide, Attempted

United States
University of Sao Paulo

Unknown

Intramuscular Ketamine Versus Aripiprazole and Escitalopram in the Treatment of Resistant Depression (KETProject)

Depressive Disorder

Brazil
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Recruiting

Early Treatment of Vulnerable Individuals With Non-Severe SARS-CoV-2 Infection (COVERAGE-A)

Covid19 | SARS-CoV2 Infection | Severe Acute Respiratory Syndrome Coronavirus 2 | Covid19 Drug Treatment

Burkina Faso, Guinea
Susanna Naggie, MD
Vanderbilt University Medical Center; National Center for Advancing Translational...

Active, not recruiting

ACTIV-6: COVID-19 Study of Repurposed Medications

Covid19

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Ibrutinib on the Pharmacokinetics of Oral Contraceptives, CYP2B6, and CYP3A4 Substrates in Female Participants With B Cell Malignancy

Leukemia, Lymphocytic, Chronic, B-Cell

Spain, Poland
Technical University of Munich

Completed

Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients

Schizophrenia | Schizoaffective Disorders | Schizophrenia and Disorders With Psychotic Features

Germany
New York State Psychiatric Institute

Completed

NMDA Antagonists in Bipolar Depression

Bipolar Disorder

United States
Shanghai Mental Health Center
The First Affiliated Hospital of Nanchang University; West China Hospital; Guizhou... and other collaborators

Recruiting

Pragmatic Trial of Obsessive-compulsive Disorder (Proceed)

Obsessive-Compulsive Disorder

China
Celgene

Completed

Study Evaluating the Effects of Food, Cytochrome P450 Inhibition and Induction on the Pharmacokinetics of CC-122

Healthy Volunteer

United States
Indiana University
National Institute of General Medical Sciences (NIGMS)

Completed

CYP2B6 Genetics and Drug Interactions in Healthy Volunteers

Healthy

United States
Organon and Co

Completed

An Observational Drug Utilization Study of Asenapine in the United Kingdom (P08308)

Bipolar Disorder
Celgene

Completed

A Phase 1 Open-Label Study to Evaluate the Effect of CYP450 and P-gp Inhibition and Induction on the Pharmacokinetics of Pomalidomide (CC-4047) in Healthy Male Subjects (DDI)

Healthy | Pharmacology, Clinical

United States
National Institute of Mental Health (NIMH)

Completed

Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)

Bipolar Disorder

United States
Eurnekian Public Hospital

Completed

Ivermectin, Aspirin, Dexamethasone and Enoxaparin as Treatment of Covid 19 (IDEA)

Severe Acute Respiratory Syndrome | Ventilation Pneumonitis

Argentina
Thomas Jefferson University

Active, not recruiting

Effectiveness of an Enhanced Tobacco Intervention Protocol Compared to Standard Treatment in Helping Head and Neck and Lung Cancer Patients Starting Treatment to Reduce Cigarette Use

Head and Neck Squamous Cell Carcinoma | Lung Non-Small Cell Carcinoma

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Study Of Fluzoparib (SHR3162) on Patients With Recurrent Ovarian Cancer

Recurrent Ovarian Cancer

China
Samsung Medical Center

Unknown

Pharmacogenomic Study to Predict Antidepressant Responsiveness in Depressed Patients

Depression | Adverse Reaction to Drug

Korea, Republic of
Samsung Medical Center

Unknown

Predict Antidepressant Responsiveness Using Pharmacogenomics

Depression | Depressive Symptoms

Korea, Republic of
Chonnam National University Hospital

Recruiting

Psychopharmacotherapy for Depressive Patients (BMDD-2022)

Major Depressive Disorder

Korea, Republic of
University of Oxford

Recruiting

Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV) (PLATCOV)

COVID-19

Lao People's Democratic Republic, Thailand, Brazil, Pakistan
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

The Effects of Multiple Dose Fluoxetine and Metabolites on CYP1A2, CYP2C19, CYP2D6 and CYP3A4 Activity (FLUOXETINE)

Healthy Volunteers | Drug-Drug Interaction
MaineHealth
Robert Wood Johnson Foundation

Completed

Early Detection and Intervention for the Prevention of Psychosis (EDIPP)

Depression | Psychotic Disorders | Schizophrenia | Bipolar Disorder

United States
Samsung Medical Center

Unknown

Prediction of Antidepressant Response Using Pharmacogenetics and Peripheral Lymphocytic Phenotype

Depression

Korea, Republic of
Federico II University

Recruiting

Comparison of Vortioxetine Versus Other Antidepressants With Pregabalin Augmentation in Burning Mouth Syndrome

Burning Mouth Syndrome

Italy
Bristol-Myers Squibb

Completed

A Study to Assess the Effect of BMS-986419 on the Single Dose Drug Levels of Probe Substrates in Healthy Participants

Healthy Volunteers

United States
Mark Vander Weg
VA Office of Research and Development

Unknown

Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers

Tobacco Use | Nicotine Dependence

United States
National Institute of Mental Health (NIMH)

Completed

Combining Medications to Enhance Depression Outcomes (CO-MED)

Major Depressive Disorder

United States
Pfizer

Completed

Voxelotor CYP and Transporter Cocktail Interaction Study

Sickle Cell Disease

United States
Pfizer

Completed

Non-interventional, Retrospective Cohort Study to Explore Antidepressant Treatment in Korea

Major Depression

Korea, Republic of
Janssen-Cilag International NV

Withdrawn

A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant
Iowa City Veterans Affairs Medical Center
US Department of Veterans Affairs

Completed

Tailored Tobacco Quitline for Rural Veterans

Cigarette Smoking

United States
Mark Vander Weg
Iowa City VA Health Care System

Unknown

Treating Smokeless Tobacco Use in Rural Veterans

Nicotine Dependence | Smokeless Tobacco

United States
Pfizer

Completed

Drug Drug Interaction Study Evaluating the Effect of Fluvoxamine or Fluconazole on PK and Safety of PF-04965842.

Dermatitis, Atopic

Belgium
Emory University

Completed

Effects of Treatment on Decision-making in Major Depression

Major Depressive Disorder | Healthy Controls

United States
Eisai Inc.

Completed

A 2-Part Study to Assess Potential Metabolism-Based Drug-Drug Interactions of E2006 When Coadministered With Itraconazole, Rifampin, Midazolam, or Bupropion

Healthy Subjects

United States
National Cancer Institute (NCI)

Completed

Bevacizumab and Low-Dose Cyclophosphamide in Treating Patients With Recurrent Ovarian Epithelial or Primary Peritoneal Cancer

Recurrent Ovarian Carcinoma | Primary Peritoneal Carcinoma | Stage IV Ovarian Cancer

United States
Duke University
National Institute of Mental Health (NIMH)

Completed

Treatment of Obsessive Compulsive Disorder in Children

Obsessive-Compulsive Disorder

United States
Louisiana State University Health Sciences Center...
Tulane University; Pennington Biomedical Research Center; Ochsner Health System

Recruiting

Anti-obesity Pharmacotherapy and Inflammation

Obesity

United States
Dr. Inge Winter
Universität Münster

Not yet recruiting

Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure (INTENSIFY)

Bipolar Depression | Major Depressive Disorder | Schizophrenia and Related Disorders

Israel
Ajay Wasan, MD, Msc
Mayo Clinic; National Institute of Arthritis and Musculoskeletal and Skin Diseases... and other collaborators

Recruiting

Treating Negative Affect in Low Back Pain Patients (TNA-LBP)

Chronic Low Back Pain | Negative Affectivity

United States
Abliva AB

Completed

Drug-drug Interaction Study of KL1333 in Healthy Subjects

Mitochondrial Disease

United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects

Healthy

Belgium

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