Search clinical trials for: VX-440

Total 8133 results

Phathom Pharmaceuticals, Inc.

Withdrawn

Evaluation of Effect of Rifampin on the Pharmacokinetics of Vonoprazan in Healthy Participants

Healthy Participants

United States
Shanghai Public Health Clinical Center

Completed

The Drug Interaction Between Albuvirtide (ABT) and Rifampin（RIF） in Healthy Adult Subjects

Drug Interaction

China
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Effect of Single-Dose Intravenous Rifampin as a Prototypic Inhibitor of Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 on the Single-Dose Pharmacokinetics (PK) of Oral TAK-906 in Healthy Adult Participants

Healthy Volunteers

United States
Eli Lilly and Company

Completed

A Study of Baricitinib and Rifampicin in Healthy Participants

Healthy Volunteers

United Kingdom
National University Hospital, Singapore

Suspended

Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Rifampicin in Healthy Volunteers

Tuberculosis

Singapore
Hoffmann-La Roche

Completed

A Study to Investigate the Effects of Rifampicin on the Pharmacokinetics of Aleglitazar in Healthy Volunteers

Healthy Volunteer

United Kingdom
Janssen Research & Development, LLC

Completed

A Drug Interaction Study in Healthy Participants to Assess the Effect of Rifampin on the Pharmacokinetics of JNJ-42847922

Healthy

United States
Bristol-Myers Squibb

Withdrawn

A Study of the Interaction of Rifampin and Vinflunine in Subjects With Advanced Cancer

Cancer

United States
University Medicine Greifswald

Completed

Impact of Two Genetic Variants of OATP1B3 or MRP2 or Rifampin on Systemic Disposition and Biological Efficacy of CCK-8

Gastrointestinal Hormones

Germany
Pfizer

Completed

Understanding The Effect Of A Strong CYP3A4 Inducer On Glasdegib Pharmacokinetics

Healthy Volunteers

United States
PENTA Foundation
Medical Research Council; ANRS, Emerging Infectious Diseases

Unknown

BREATHER (PENTA 16) Short-Cycle Therapy (SCT) (5 Days on/2 Days Off) in Young People With Chronic HIV-infection (BREATHER)

HIV

United Kingdom, Uganda, Ireland, United States, France, Germany, Thailand, Ukraine
Pfizer
ViiV Healthcare

Terminated

A Long Term Safety Study Of Lersivirine For The Treatment Of HIV-1 Infection In Subjects Who Have Completed Treatment With Lersivirine In Studies A5271015 And A5271022

HIV-1

South Africa, Australia, United Kingdom, Canada, Italy, Poland, Switzerland, Mexico, Brazil
AstraZeneca

Completed

To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers

Solid Tumours

United States
Michael Hoelscher
Quintiles, Inc.; German Federal Ministry of Education and Research; Parexel; European... and other collaborators

Completed

Early Bactericidal Activity (EBA) of SQ109 in Adult Subjects With Pulmonary TB (SQ109EBA)

Tuberculosis, Pulmonary

South Africa
AstraZeneca

Completed

Effects of Administration of Fostamatinib on Blood Concentrations of Rifampicin in Healthy Subjects.

Rheumatoid Arthritis | Healthy Volunteers

United States
Bristol-Myers Squibb
PRA Health Sciences

Completed

Drug-Drug Interaction Study With Rifampin

Alzheimer Disease

India
Institut Bergonié

Unknown

Efavirenz as Second-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer

Pancreatic Cancer

France
Bristol-Myers Squibb

Completed

Study Switching HIV-1 Infected Patients With an Undetectable Viral Load on a First Protease Inhibitor-Based Regimen to an Efavirenz-Based Regimen

HIV Infections

United States, Puerto Rico
PharPoint Research, Inc.

Withdrawn

Study to Evaluate Phenobarbital Sodium Injection for the Treatment of Neonatal Seizures

Neonatal Seizure
Medicines for Malaria Venture
AbbVie

Completed

Malaria: Relative Bioavailability and Food Effect of DSM265

Healthy Volunteers

United States
Vertex Pharmaceuticals Incorporated

Terminated

Telaprevir, Peg-IFN-alfa-2a, and RBV in Treatment-Experienced Black/African American and Non-Black/African American Subjects With Genotype 1 Chronic Hepatitis C

Hepatitis C

United States
Eisai Inc.

Completed

Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazole, Itraconazole, or Rifampin in Healthy Subjects

Healthy Participants

United States
Tourcoing Hospital

Recruiting

Rifabutin Versus Rifampicin for Treatment of Staphylococcal PJI Treated With DAIR (RIFAMAB)

Prosthetic Infection

France
University of Cape Town

Recruiting

High vs. Standard Dose Rifampicin for Effusive Tuberculous Pericarditis (IMPI-3)

HIV Status | Tuberculous Pericarditis

South Africa
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test Whether Rifampicin Influences the Amount of BI 894416 in the Blood

Healthy

Germany
Rennes University Hospital

Completed

EVRIOS : Comparative Evaluation of Low Versus High Doses of Rifampicin (EVRIOS)

Osteoarticular Infection

France
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-Drug Interaction of SHR1459 With a Strong CYP3A Index Inducer (Rifampicin)

Healthy Subjects, Drug-drug Interaction, Pharmacokinetics, SHR1459

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Rifampin Effect Study of SHR2554 on Healthy Chinese Adult Subjects

Healthy

China
Peking Union Medical College Hospital

Unknown

Efficacy of Efavirenz 400mg vs. 600mg Combined With Lamivudine and Tenofovir in Treatment Naive HIV Infection

HIV/AIDS | Mental Impairment

China
AstraZeneca

Completed

A Study in Healthy Subjects to Assess the Pharmacokinetics of Savolitinib When Administered Alone and in Combination With Rifampicin

Solid Tumors

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Trial of Rifampicin Pharmacokinetics Effect on Fluzoparib

Healthy Male Subjects

China
Sichuan Haisco Pharmaceutical Group Co., Ltd

Completed

A Study Evaluating Drug-Drug Interaction (DDI) Between HSK3486 Injectable Emulsion and Rifampin Capsules

Anesthesia | Sedation

China
Bristol-Myers Squibb

Completed

An Investigational Study of Experimental Medication BMS-986278 Given With the Antibiotic Rifampin in Healthy Participants

Healthy Participants

United States
Enanta Pharmaceuticals, Inc

Completed

Drug-drug Interaction Study Between EDP-305, Intraconazole and Rifampin in Healthy Volunteers

NASH - Nonalcoholic Steatohepatitis

United States
Adeniyi Olagunju
Obafemi Awolowo University Teaching Hospital; University of Liverpool

Completed

A Study to Evaluate the Effects of Genetic Factors on the Pharmacokinetics of Antiretroviral Drugs During Pregnancy and Lactation

Pregnancy | HIV | Breastfeeding

Nigeria
University of Minnesota

Completed

Sustiva Levels With Use of a Gel Capsule

HIV Infections | HIV

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Effect of Rifampin on the Single-dose Pharmacokinetics (PK) of BMS-986141 in Healthy Subjects

Atherothrombotic Diseases
Bristol-Myers Squibb

Completed

A Study to Evaluate the Effect of Rifampin on the Single-dose Pharmacokinetics of BMS-986177 in Healthy Subjects

Thrombosis
Kowa Research Institute, Inc.

Completed

Drug-Drug Interaction Study in Healthy Adult Volunteers

Healthy

United States
University of Oulu
Oulu University Hospital

Completed

The Effect of PXR Activation on Blood Pressure Regulation

Blood Pressure Regulation

Finland
Bristol-Myers Squibb

No longer available

An Expanded Access Study of Oral Liquid Efavirenz in the Treatment of Children With HIV Infection

HIV Infection

United States, Puerto Rico
Janssen-Cilag International NV

Completed

A Clinical Trial Comparing the Tolerability of Etravirine to Efavirenz in Combination With 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Treatment-naive HIV-1 Infected Patients (SENSE)

Acquired Immunodeficiency Syndrome | HIV Infection | HIV

France, United Kingdom, Germany, Spain, Switzerland, Israel, Russian Federation, Austria, Hungary, Romania, Denmark
Abbott

Completed

Effect of Rifampin on the Pharmacokinetics of Linifanib in Subjects With Advanced or Metastatic Solid Tumors

Advanced Solid Tumors

United States
Hadassah Medical Organization

Unknown

Genetic Variability in the Response to Warfarin at Baseline and During Induction of CYP2C9

Healthy Subjects

Israel
St Stephens Aids Trust

Completed

Pilot Study Switching Individuals Receiving EFV With Continuing Central Nervous System Toxicity to TMC125

HIV

United Kingdom
Centers for Disease Control and Prevention
University of Alabama at Birmingham; Universidad del Valle, Guatemala

Completed

Clinical Trial of Rifampin and Azithromycin for the Treatment of River Blindness

Onchocerciasis

Guatemala
National Center for Research Resources (NCRR)
National Multiple Sclerosis Society

Completed

Antibiotic Treatment Trial Directed Against Chlamydia Pneumonia in Multiple Sclerosis

Multiple Sclerosis

United States
Xuanzhu Biopharmaceutical Co., Ltd.

Recruiting

Effect of Clarithromycin and Rifampicin on the Pharmacokinetics of XZP-3287 in Healthy Subjects

Healthy

China
Actelion

Completed

A Clinical Study to Investigate the Effect of Gemfibrozil or Rifampicin on Blood Concentrations of Selexipag in Healthy Subjects

Healthy Subjects

Germany
Assiut University

Not yet recruiting

Efficacy Of Doxycycline & Versus Rifampin In Treatment Of Rhinoscleroma

Rhinoscleroma

3

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