Search clinical trials for: VX-745

Total 1498 results

Hepion Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of Rencofilstat in Adult Subjects With NASH F3 (ALTITUDE)

NASH With Fibrosis

United States
Pfizer

Completed

Efficacy and Safety Study of Rimegepant for the Acute Treatment of Migraine in Japanese Subjects (Japan Only)

Migraine

Japan
Chang Gung Memorial Hospital

Completed

The Aging Brain and Cognition: Contribution of Vascular Injury, Amyloid Plaque and Tau Protein to Cognitive Dysfunction After Stroke

Post-stroke Dementia | Vascular Mild Cognitive Impairment

Taiwan
Hospital Universitario Dr. Jose E. Gonzalez

Completed

Association Between Low Plasma Glucose After Oral Glucose Tolerance Test in Pregnancy With Impaired Fetal Growth

Low Birth Weight | Oral Glucose Tolerance Test

Mexico
NanoFUSE Biologics, LLC

Unknown

NanoFUSE® PL Gutter PMCF

Degenerative Disc Disease
EMD Serono

Completed

Efficacy and Safety of Atacicept in Systemic Lupus Erythematosus (ADDRESS II)

Lupus Erythematosus, Systemic

Korea, Republic of, Philippines, Spain, United States, Czechia, Germany, United Kingdom, South Africa, Poland, Argentina, Italy, Chile, Bulgaria, Japan, Brazil, Mexico, Peru, Russian Federation
Ghulam Nabi

Completed

Link Between the Sensitivity of Kisspeptin Signalling and Pubertal Onset in Boys.

Reproductive Physiological Phenomena

Pakistan
EMD Serono
Merck KGaA, Darmstadt, Germany

Completed

Atacicept Phase 2/3 in Generalized Systemic Lupus Erythematosus (APRIL-SLE) (APRIL-SLE)

Lupus Erythematosus, Systemic

United States, Croatia, Bulgaria, France, Korea, Republic of, Poland, Russian Federation, South Africa, Spain, United Kingdom, Germany, Malaysia, Latvia, Lithuania, Ukraine, Argentina, Israel, Netherlands, Greece, Taiwan, Philip... and more
Avid Radiopharmaceuticals

Completed

Evaluation of Web-based Training to Educate Physicians in the Methods of Interpreting Florbetapir-PET Scans

Neurodegenerative Diseases | Alzheimer Disease | Mild Cognitive Impairment
Avid Radiopharmaceuticals

Completed

Evaluation of PET Scan Timing Relative to AV-45 Injection Time

Alzheimer's Disease
Avid Radiopharmaceuticals

Completed

Autopsy Follow-up of Subjects Previously Imaged With Florbetapir F 18 (18F-AV-45) PET in Trial 18F-AV-45-A07

Alzheimer's Disease

United States
Avid Radiopharmaceuticals

Completed

A Study of 18F-AV-45 in Healthy Volunteers

Alzheimer Disease

United States
Avid Radiopharmaceuticals

Completed

Evaluation of Inter-reader Reliability Using Images From Subjects With Alzheimer's Disease (AD) or Mild Cognitive Impairment (MCI)

Alzheimer's Disease
Chang Gung Memorial Hospital

Completed

Pathophysiology of Neurodegeneration in Late-life Depression (AV45+THK)

Major Depressive Disorder

Taiwan
Avid Radiopharmaceuticals

Completed

Clinical Evaluation of Florbetapir F 18 (18F-AV-45)

Neurodegenerative Diseases | Alzheimer Disease | Mild Cognitive Impairment

United States
Eli Lilly and Company

Completed

A Non-drug Methods Study in Participants With Alzheimer's Disease

Alzheimer's Disease

France
Avid Radiopharmaceuticals

Completed

Evaluation of Reader Training Processes

Alzheimer's Disease

United States
Avid Radiopharmaceuticals

Completed

A Preliminary Study of 18F-AV-45 in Alzheimer's Disease and Healthy Elderly Volunteers

Alzheimer Disease

United States
Avid Radiopharmaceuticals

Completed

A Study of 18F-AV-45 in Alzheimer's Disease (AD) and Healthy Volunteers

Alzheimer's Disease

United States
Akros Pharma Inc.

Completed

Efficacy and Safety Study of JTT-705 in Combination With Pravastatin 40 mg in Patients With Type II Hyperlipidemia

Type II Hyperlipidemia

Netherlands
Gilead Sciences

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of GS-5745 (Andecaliximab) in Adults With Moderate to Severe Active Ulcerative Colitis

Ulcerative Colitis

United States, Belgium, Netherlands, Canada, Hungary, Moldova, Republic of, Romania
Edison Pharmaceuticals Inc

Completed

Protective Effects of EPI-743 on Noise-Induced Hearing Loss

Noise-induced Hearing Loss

United States
Institute of Vaccines and Medical Biologicals,...
Department of Health and Human Services; Institut Pasteur; PATH; World Health Organization

Completed

Influenza A/H5N1 Vaccine Clinical Trial (IVACFLU-A/H5N1) - Phase 1

Influenza A Subtype H5N1 Infection

Vietnam
Pfizer

Completed

Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenail

Onychomycosis

Mexico
Javelin Pharmaceuticals

Completed

Efficacy and Safety of Intranasal Morphine for Pain After Bunion Surgery

Hallux Valgus
Affiliated Hospital of Jiaxing University

Completed

Effects of Permissive Hypercapnia on Concentration of Postoperative Plasma Neurofilament Light

Hypercapnia

China
EMD Serono
Merck KGaA, Darmstadt, Germany

Terminated

Atacicept in Multiple Sclerosis Extension Study, Phase II (ATAMS ext)

Relapsing Multiple Sclerosis

Sweden, United States, Czech Republic, Russian Federation, Spain, United Kingdom, Lithuania, Ukraine, Netherlands, Canada, Germany, France, Switzerland, Australia, Belgium, Lebanon, New Caledonia
Avid Radiopharmaceuticals
Eli Lilly and Company

Completed

A Study of Florbetapir (18F) in Japanese Healthy Volunteers

Alzheimer's Disease

Japan
Intercept Pharmaceuticals

Completed

Phase 2 Study on Effects of Obeticholic Acid (OCA) on Lipoprotein Metabolism in Participants With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
University Health Network, Toronto

Unknown

Impact of Low Frame Rate Fluoroscopy and Cine-angiography on Reducing Operator and Patient Dose

Acute Coronary Syndrome | Stable Angina | Unstable Angina

Canada
Solvay Pharmaceuticals

Completed

Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Female Subjects

Atrial Fibrillation | Atrial Flutter

Russian Federation, Romania, United States, Argentina, Czech Republic, Former Serbia and Montenegro, Germany, Israel, Poland, Slovakia, South Africa, Ukraine, United Kingdom
MedImmune LLC

Completed

A Multicenter Study to Evaluate the Safety and Tolerability of Single-Dose for MEDI-545 (CP145)

Chronic Plaque Psoriasis

Canada
Vertex Pharmaceuticals Incorporated

Completed

Phase 2 Study of VX-950, Pegasys® With and Without Copegus® in Hepatitis C

Chronic Hepatitis C

Austria, France, Germany, United Kingdom
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

Predictive Value of Mid-luteal Serum Progesterone Levels in Egg Donation Cycles

Pregnancy

Spain
Amgen

Completed

Efficacy and Safety of Romosozumab Treatment in Postmenopausal Women With Osteoporosis (FRAME)

Postmenopausal Osteoporosis

United States, Canada, Denmark, Germany, Belgium, Colombia, Czechia, Japan, Mexico, Poland, Switzerland, Hungary, Spain, Australia, Romania, United Kingdom, India, Argentina, Brazil, Dominican Republic, Estonia, Latvia, Lithuania, New...
Johnson & Johnson Pharmaceutical Research & Development...
PharmaMar

Completed

A Phase 2 Study of Trabectedin (Yondelis) in Adult Male Participants With Advanced Prostate Cancer

Prostate Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Metastatic Pancreatic Carcinoma | Refractory Malignant Solid Neoplasm | Refractory Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Unresectable Pancreatic Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Unresectable Malignant... and other conditions

United States
Boehringer Ingelheim

Completed

Study of Relative Bioavailability of Mobic Manufactured in China in Comparison With Mobic Manufactured in Germany in Chinese Healthy Volunteers

Healthy
Alto Neuroscience

Recruiting

PD, PK, and Safety of ALTO-203 in Patients With MDD

Anhedonia | Major Depressive Disorder

United States
University of Oxford

Recruiting

A Study of the Plasmodium Falciparum Malaria Vaccine Candidate Pfs48/45 in Matrix-M Adjuvant in the UK

Malaria | Plasmodium Falciparum

United Kingdom
Sumitomo Pharma Co., Ltd.

Terminated

A Clinical Trial to Evaluate the Efficacy and Safety of SEP-363856 in Acutely Psychotic People With Schizophrenia, Followed by an Open-label Extension Phase

Schizophrenia

Japan, Taiwan, China, Philippines
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Clinical Trial of Sodium Nitrite for Out of Hospital Cardiac Arrest (SNOCAT)

Out-Of-Hospital Cardiac Arrest

United States
Clinica las Condes, Chile

Completed

Effects of Trunk Postural Change on CO2 Removal Efficiency in ARDS Patients: Quasi-experimental Study

ARDS

Chile
University of Thessaly

Completed

Recovery Kinetics Following Eccentric Exercise

Muscle Damage

Greece
Avid Radiopharmaceuticals
Eli Lilly and Company

Completed

A Phase II Trial of Florbetapir (18F) Positron Emission Tomography (PET) Imaging in Japan of Healthy Volunteers, Patients With Mild Cognitive Impairment (MCI) and Patients With Alzheimer's Disease (AD)

Mild Cognitive Impairment | Alzheimer's Disease

Japan
Fluisense ApS
Dantrials Aps

Completed

Clinical Validation of the Fluispotter System for Serial Sampling of Venous Dried Blood Spots

Healthy | Blood Sampling Procedure

Denmark
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Indacaterol Acetate Delivered Via the Concept1 Inhalation Device in Children Greater or Equal to 6 and Less Than 12 Years of Age With Asthma

Asthma

South Africa, Belgium, Croatia, Turkey, Hungary, Colombia, Slovakia, Philippines, Russian Federation, Guatemala, Germany
Avid Radiopharmaceuticals

Completed

The Feasibility of Florbetapir Quantitation in Europe

Alzheimer's Disease

Netherlands
Leiden University Medical Center
Dutch Colorectal Cancer Group; Stichting Darmkanker

Not yet recruiting

DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients With Metastatic Colorectal Cancer (DOSAGE)

Colorectal Cancer | Metastatic Cancer | Older Patients | Candidates for Palliative Chemotherapy

Netherlands
Novartis Pharmaceuticals

Completed

16 Week Efficacy and 5 Year Long Term Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Ankylosing Spondylitis (MEASURE2)

Anklyosing Spondylitis

Germany, Austria, Spain, Switzerland, United Kingdom, United States, Singapore, Russian Federation, Netherlands, Italy, Finland, Czechia, Canada

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