Search clinical trials for: VX-745

Total 1491 results

Jimmy Barbalho
University of Pernambuco

Completed

Comparative Study of Hemodynamic Changes Caused by Diazepam and Midazolam During Third Molar Surgery

Anxiety

Brazil
The University of Hong Kong

Completed

Effect of Application Time of 38% Silver Diamine Fluoride Solution on Arresting Dental Caries in Preschool Childre

Early Childhood Caries

Hong Kong
University of Colorado, Denver

Terminated

Phase I Nicotinic Agonist Treatment Trial for Autism

Autism

United States
Boehringer Ingelheim

Completed

Study to Compare the the Analgesic Efficacy and Tolerability of Meloxicam Versus Placebo and Ibuprofen in the Treatment of Pain After Surgery of the Third Molar

Pain
George Washington University
Columbia University; Harvard School of Public Health (HSPH); Ifakara Health Institute and other collaborators

Not yet recruiting

Multiple Micronutrient Supplementation for Maternal Anemia Prevention in Tanzania (MMS-MAP)

Pregnancy Related
George Washington University
Columbia University; Harvard School of Public Health (HSPH); Ifakara Health Institute and other collaborators

Not yet recruiting

Multiple Micronutrient Supplementation (MMS) Iron Dose Acceptability Crossover Trial

Pregnancy Related
Center Laboratories, Inc.

Terminated

R-Verapamil for the Prophylaxis of Episodic Cluster Headache

Episodic Cluster Headache

United Kingdom
Novo Nordisk A/S

Completed

Safety, Pharmacokinetics and Pharmacodynamics of Two IDegAsp (One Explorative) Preparations and Two Insulin Degludec (One Explorative) Preparations in Japanese Subjects

Healthy | Diabetes

Japan
Seoul National University Hospital

Completed

PET in Breast Cancer Receiving Neoadjuvant Chemotherapy (DA-PET)

Breast Cancer
Clear Creek Bio, Inc.

Terminated

Brequinar Combined With Dipyridamole in Patients With Mild to Moderate COVID-19 (CCBCRISIS04)

COVID-19

India
Sahlgrenska University Hospital, Sweden

Completed

The Effects of Blood Pressure on Renal Function and Oxygenation in Septic Shock

Septic Shock | Acute Kidney Injury

Sweden
gicare Pharma Inc.
Algorithme Pharma Inc

Completed

Study on Analgesia of GIC-1001 & GIC-1002 on Visceral Pain, Rectal Sensory Threshold Using the Barostat Method

Pain | Cancer | Colonic Disease

Canada
Rovi Pharmaceuticals Laboratories

Completed

Study to Evaluate the Efficacy and Safety of Risperidone ISM® in Patients With Acute Schizophrenia: Open Label Extension (PRISMA-3_OLE)

Schizophrenia

United States, Ukraine
Aires Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and PK Parameters of Sodium Nitrite Inhalation Solution in Healthy Subjects

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States
IBSA Institut Biochimique SA

Recruiting

A New Sildenafil Oral Film in Patients With Erectile Dysfunction

Erectile Dysfunction

United States
Actelion

Recruiting

Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension (UNISUS)

Pulmonary Arterial Hypertension

Belgium, United States, Italy, Canada, Taiwan, Greece, China, Korea, Republic of, Germany, Israel, Austria, Russian Federation, Australia, Thailand, United Kingdom, Brazil, Malaysia, Spain, Ukraine, Bulgaria, Colombia, Mexico, Turkey, Vietna... and more
Virginia Polytechnic Institute and State University

Completed

The Role of Altered Nutrient Partitioning in Food Reward

Overweight and Obesity

United States
Medical University of Vienna

Completed

Gastric Emptying of High Calorie Liquid Meals

Gastric Emptying

Austria
American-European Congress of Ophthalmic Surgery

Terminated

Safety & Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus or Corneal Ectasia After Refractive Surgery

Keratoconus | Corneal Ectasia

United States, Puerto Rico
Bristol-Myers Squibb

Completed

UNITY 3: A Japanese Phase 3 Study of a Daclatasvir/Asunaprevir/BMS-791325 in Subjects With Genotype 1 Chronic Hepatitis C

Hepatitis C Virus Infection

Japan
University Hospital, Gentofte, Copenhagen
Danish Heart Foundation

Completed

Vasodilatory and Metabolic Effects of Glucagon-like Peptide-1 in Periphery Circulation in Patients With and Without Type 2 Diabetes Mellitus

Type 2 Diabetes | Blood Flow | Human Physiology | Glucagon-like Peptide-1 | Blod Pressure

Denmark
Biotronik SE & Co. KG

Completed

TD01 Master Study (Safety and Efficacy Study)

ICD/CRT-D Indication

Germany, Austria
Impax Laboratories, LLC

Completed

A Study to Assess the PK and Pharmacodynamics of IPX203 in Patients With Advanced Parkinson's Disease

Parkinson's Disease

United States
Noven Therapeutics

Completed

Eight-Week Efficacy & Safety Study of Brisdelle™ (Formerly Known as Mesafem) in the Treatment of Vasomotor Symptoms Associated With Menopause

Hot Flashes

United States
Lars Olaf Cardell

Recruiting

Intralymphatic Immunotherapy Enhanced by Vitamin-D, a Randomized Placebo-controlled Trial and Comparison With SLIT (ILIT vs SLIT)

Allergic Rhinitis Due to Grass Pollen

Sweden
Hvivo

Completed

Characterisation of a New Wild-Type H3N2 Virus for the Human Viral Challenge Model

Influenza
Janssen Research & Development, LLC

Terminated

A Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Anti-TNFα Naive Participants With Active Radiographic Axial Spondyloarthritis

Axial Spondyloarthritis

United States, Ukraine, Taiwan, Poland, Korea, Republic of, Russian Federation, Czechia
Janssen Research & Development, LLC

Terminated

A Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Anti-TNF(Alpha) Refractory Participants With Active Radiographic Axial Spondyloarthritis

Axial Spondyloarthritis

United States, Canada, France, Ukraine, United Kingdom, Belgium, Germany, Taiwan, Spain, Argentina, Mexico, Poland, Portugal, Bulgaria, Korea, Republic of, Brazil, Russian Federation, Hungary, Czechia
Allergan
MAP Pharmaceuticals, Inc., a wholly owned subsidiary of Allergan

Completed

Pharmacokinetics & Tolerability Study of MAP0004 in Smoking and Non-Smoking Adult Volunteers

Healthy Subjects

United Kingdom
Assiut University

Not yet recruiting

Coronary Artery Ectasia, Efficacy of Various Anti Thrombotic Regimens.

Coronary Artery Ectasia
HighField Biopharmaceuticals Corporation
Tigermed Consulting Co., Ltd

Recruiting

Tolerability and Safety of HF1K16 Injection in Patients With Refractory Solid Tumors

Solid Tumor, Adult

China
VA Office of Research and Development

Completed

Modulation of the Intestinal Microbiome by a High Protein Diet (HPD)

Obesity

United States
Beijing Health Guard Biotechnology, Inc
National Institutes for Food and Drug Control, China; Jiangsu Province Centers... and other collaborators

Completed

A Phase II Trial Evaluate the Immunogenicity and Safety Profile of HPV Vaccine

Human Papilloma Virus Infection

China
University of Pennsylvania
3M

Completed

Efficacy Comparison of Two Preoperative Skin Antisepsis Preparations in Colorectal Surgery

Colorectal Surgery

United States
Milton S. Hershey Medical Center

Terminated

Oncaspar/Doxil/Decadron in Patients With Refractory Lymphoid Malignancies

Multiple Myeloma | Hodgkins Lymphoma | Non-hodgkins Lymphoma

United States
Cephalon

Completed

A Study to Assess the Abuse Potential of Hydrocodone Extended-Release Tablet in Recreational Opioid Users

Drug Abuse

United States, Canada
Organon and Co

Completed

The Single Dose Pharmacokinetics of Two and Proof of Efficacy of One New Etoricoxib Gel Formulation in Participants With Osteoarthritis (MK-0663-168)

Osteoarthritis Pain
Millennium Pharmaceuticals, Inc.

Completed

A Study of Pevonedistat in Adult East Asian Participants

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

Japan, Taiwan, Korea, Republic of
Masonic Cancer Center, University of Minnesota

Active, not recruiting

Reduced Intensity (RIC) Conditioning And Transplantation of HLA-Haplo-HCT

Hematologic Malignancies

United States
Beijing Health Guard Biotechnology, Inc

Active, not recruiting

A Phase III Trial Evaluates the Efficacy, Immunogenicity and Safety Profile of HPV Vaccine

Human Papillomavirus Infection

China
Rovi Pharmaceuticals Laboratories

Recruiting

Evaluation of the Pharmacokinetics, Safety, and Tolerability of IM Letrozole LEBE in Healthy Post-menopausal Women (LEILA-1)

Healthy

Czechia
Emergent BioSolutions
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Safety and Pharmacokinetics of UV-4B Solution Administered Orally as Multiple Ascending Doses to Healthy Subjects

Viral Infection

United States
Stephanie B. Seminara, MD

Enrolling by invitation

Opioid Antagonism in Hypogonadotropic Hypogonadism

Hypogonadotropic Hypogonadism

United States
VA Office of Research and Development

Completed

Gastrointestinal Hormonal Regulation of Obesity

Obesity

United States
Jaeb Center for Health Research
Xeris Pharmaceuticals

Completed

Mini-Dose Glucagon to Treat Non-Severe Hypoglycemia

Diabetes Mellitus, Type 1

United States
Cairo University

Unknown

Accuracy of Ultrasound Markers Versus Biochemical Markers in Prediction of Ovarian Response in Obese Women Undergoing IVF/ICSI Treatment

Invitro Fertilization

Egypt
Alberta Children's Hospital
The Hospital for Sick Children; British Columbia Children's Hospital; Stollery...

Terminated

Safety and Dosing Study of Glucagon-like Peptide 2 (GLP-2) in Infants and Children With Intestinal Failure (GLP-2-01)

Short Bowel Syndrome | Intestinal Failure

Canada
Bill & Melinda Gates Medical Research Institute

Not yet recruiting

Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population

Healthy Volunteers

Kenya, Uganda
University of Texas Southwestern Medical Center

Completed

Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer

Prostate Cancer

United States
Ferring Pharmaceuticals

Completed

A Study Comparing MENOPUR in a Pen Formulation With a Powder and Solvent Formulation in Healthy Women

Infertility, Female

China

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