Search clinical trials for: Verubecestat (Part II)

Total 9883 results

Merck Sharp & Dohme LLC

Terminated

An Efficacy and Safety Trial of Verubecestat (MK-8931) in Mild to Moderate Alzheimer's Disease (P07738) (EPOCH)

Alzheimer's Disease
Merck Sharp & Dohme LLC

Terminated

Efficacy and Safety Trial of Verubecestat (MK-8931) in Participants With Prodromal Alzheimer's Disease (MK-8931-019) (APECS)

Alzheimer's Disease | Amnestic Mild Cognitive Impairment | Prodromal Alzheimer's Disease
Mineralys Therapeutics Inc.

Completed

Trial on the Safety and Efficacy of MLS-101 in Patients With Uncontrolled Hypertension (Target-HTN)

Hypertension, Renal

United States
Merck Sharp & Dohme LLC

Completed

An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016)

Alzheimer's Disease | Amnestic Mild Cognitive Impairment | Prodromal Alzheimer's Disease
Chong Kun Dang Pharmaceutical

Completed

Pharmacokinetics, Safety and Tolerability of CKD-387 10/500mg BE Phase1

Type2 Diabetes Mellitus

Korea, Republic of
University of Minnesota
Merck Sharp & Dohme LLC; University of Kentucky

Completed

Improving Adolescent Vaccination in Appalachian Kentucky (INSPIRE)

Adolescent Immunization

United States
Institute of Cancer Research, United Kingdom
Trans Tasman Radiation Oncology Group

Active, not recruiting

Study of Tumour Focused Radiotherapy for Bladder Cancer (RAIDER)

Bladder Cancer

United Kingdom, New Zealand, Australia
Janssen Cilag N.V./S.A.

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-38877618 in Healthy Male Participants

Healthy Volunteers

United Kingdom
Kyushu University

Recruiting

GAIA-102 Intraperitoneal Administration in Patients With Advanced Gastrointestinal Cancer of Microsatellite Stable With Malignant Ascites

Gastric Cancer | Pancreatic Cancer

Japan
National Institute for Tuberculosis and Lung Diseases...

Recruiting

PEP and OPEP Devices in Cystic Fibrosis

Cystic Fibrosis

Poland
Korea Otsuka Pharmaceutical Co., Ltd.
Otsuka Pharmaceutical Co., Ltd.

Completed

OPS-2071 Single and Multiple Dose Study to Investigate PK and PD Profile in Healthy Korean Male Subjects. (OPS-2071Ph1)

Healthy

Korea, Republic of
Organon and Co

Completed

A Two-Part 26-Week Study of Etoricoxib as Treatment for Ankylosing Spondylitis (AS) (MK-0663-108)

Spondylitis, Ankylosing
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Communication Training for Caregivers In Advanced Care Planning

Advanced Care Planning | Primary Malignant Brain Tumors

United States
Gangnam Severance Hospital

Not yet recruiting

Necessity of Post-mastectomy Radiotherapy After Neoadjuvant Chemotherapy and Mastectomy

Breast Cancer
Huahui Health

Completed

A Study to Evaluate the Safety and Pharmacokinetics of HH-120 Nasal Spray in Healthy Volunteers

COVID-19

China
Orion Corporation, Orion Pharma
PRA Health Sciences

Terminated

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effects of ODM-108: in Healthy Male Volunteers (FIMTRIP)

Healthy

Netherlands
Gustavo Reyes-Teran

Recruiting

Immediate ART in Subjects With Opportunistic Diseases

HIV/AIDS | ANTIRETROVIRAL TREATMENT

Mexico
Chiesi Farmaceutici S.p.A.

Terminated

A Study To InvestigateThe Safety, Tolerability And Efficacy Of Nebulised Curosurf® In Preterm Neonates With Respiratory Distress Syndrome (RDS)

Neonatal Respiratory Distress Syndrome

Italy
Bial - Portela C S.A.

Completed

Efficacy, Safety, and Tolerability of Eslicarbazepine Acetate in the Recurrence Prevention of Bipolar I Disorder

Bipolar I Disorder
Sunshine Lake Pharma Co., Ltd.

Completed

Evaluation Freethiadine Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of Study

Hepatitis B, Chronic

China
Eli Lilly and Company

Completed

A Study of LY3143753 and LY3185643 in Healthy Participants

Healthy

United Kingdom
AstraZeneca
Parexel

Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 Following Single and Multiple Ascending Doses Via Oral Administration to Healthy Participants

Healthy Participants

United States
AstraZeneca

Completed

A Study of AZD8233 in Participants With Dyslipidemia. (HAYATE)

Dyslipidemia

Japan
Jiangsu Rec-Biotechnology Co., Ltd.

Completed

Safety, and Immunogenicity Study of the Recombinant Two-component COVID-19 Vaccine (CHO Cell) (ReCOV)

COVID-19

Philippines
GLWL Research Inc.

Terminated

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GLWL-01

Diabetes Mellitus, Type 2

United States
Verona Pharma plc
Iqvia Pty Ltd

Completed

A Study of RPL554 Drug Administered by Metered Dose Inhaler to Treat Chronic Obstructive Pulmonary Disease

COPD

United Kingdom
Ono Pharmaceutical Co. Ltd

Completed

A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacology of ONO-4474 in Healthy Volunteers

Osteoarthritis

Denmark, United Kingdom
Chiesi Farmaceutici S.p.A.

Terminated

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD (CHF6297 FIH)

Chronic Obstructive Pulmonary Disease

United Kingdom
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD0914

Gonococcal (GC) Infection

United States
Istituto Clinico Humanitas

Completed

Risk Factors for Ectopic Pregnancy: Comparison of Fresh and Warmed Transfers. Analysis of a 10 Years, a Single Center Experience.

Ectopic Pregnancy; Assisted Reproductive Technology
Kowa Company, Ltd.

Completed

A Study to Evaluate the Safety of K-755 in Healthy Volunteers

Healthy

Australia
Janssen Research & Development, LLC

Completed

A Single Ascending Dose Study in Healthy Participants and Multiple Ascending Dose Study of CNTO 7160 in Participants With Asthma and Participants With Atopic Dermatitis

Healthy | Asthma | Atopic Dermatitis

Germany, Belgium
Amytrx Therapeutics, Inc.
Amarex Clinical Research

Completed

Topically Applied AMTX-100 CF for Adult Patients With Mild to Moderate Atopic Dermatitis

Atopic Dermatitis

United States
Sun Pharma Advanced Research Company Limited

Terminated

A Study in Patients With Advanced Breast Cancer

Advanced Breast Cancer | HER2-negative Breast Cancer | Hormone Receptor-positive Breast Cancer

United States, India
University of Pittsburgh

Completed

Effects of an 8-day Advanced Meditation, Samyama on Physical, Psychological and Spiritual Wellbeing ,and Associated Neural Mechanisms

Depression | Stress | Inflammatory Bowel Diseases | Dietary Habits | Mental Health Wellness 1 | Happiness | Consciousness, Level Altered | Ecstasy

United States
Children's Hospital of Philadelphia
Agency for Healthcare Research and Quality (AHRQ)

Completed

Improving Otitis Media Care With Clinical Decision Support (OMHIT)

Otitis Media

United States
Kanyos Bio, Inc., a wholly-owned subsidiary of...
Pfizer

Recruiting

A Study of Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of KAN-101 in Celiac Disease (ACeD-it)

Celiac Disease

United States, Australia, New Zealand
Pfizer

Completed

A Study in Normal Healthy People, Testing Different Versions of a Pill That Will be Used to Treat Rheumatoid Arthritis.

Rheumatoid Arthritis | Healthy Volunteers

United States
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of CHF6333 in Healthy Subjects (CHF6333 FIH)

Cystic Fibrosis | Non-Cystic Fibrosis Bronchiectasis

Belgium
Novartis Pharmaceuticals

Completed

A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients

Primary Biliary Cholangitis

United States, Germany, Russian Federation, Canada, United Kingdom, Poland
Indivior Inc.

Completed

Buprenorphine-Fentanyl Interaction Study

Healthy | Opioid Use

Netherlands
Verona Pharma plc
Iqvia Pty Ltd

Completed

Study Evaluating 5 Doses of RPL554 and Placebo in COPD Patients Via a Dry Powder Inhaler

Pulmonary Disease, Chronic Obstructive

United States
Emory University

Terminated

Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease

Sickle Cell Disease

United States
iN Therapeutics Co., Ltd.

Recruiting

A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients.

Pain | Osteoarthritis | Chronic Pain | Neuropathic Pain | Post Herpetic Neuralgia

Australia
AstraZeneca
Acerta Pharma, LLC

Completed

A Study to Evaluate Relative Bioavailability, Proton Pump Inhibitor (PPI) (Rabeprazole) Effect, Food Effect and Particle Size Effect of New Acalabrutinib Tablet in Healthy Subjects

Bioavailability | B-cell Lymphoid Cancer

United States
AstraZeneca

Completed

AZD1152 in Patients With Advanced Solid Malignancies

Tumors

United States
GlaxoSmithKline

Terminated

A First Time in Human Study Exploring Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK2618960 in Healthy Volunteers and Patients With Relapsing Remitting Multiple Sclerosis (RRMS)

Multiple Sclerosis, Relapsing-Remitting

United Kingdom
Ichnos Sciences SA
Glenmark Pharmaceuticals S.A.

Completed

Phase 2b Study to Evaluate the Efficacy and Safety of ISB 830 in Adults With Moderate to Severe Atopic Dermatitis

Moderate to Severe Atopic Dermatitis

United States, Canada, Czechia, Germany, Poland
Mereo BioPharma
Novartis

Terminated

Safety & Efficacy of BCT197 in Patients Undergoing Cardiac Surgery

Acute Kidney Injury

Taiwan, United States, Israel
UCB Pharma
Parexel

Completed

Study to Assess Safety, Tolerability, Pharmacokinetic & Pharmacodynamic Effect of UCB5857 in Healthy & Psoriatic Subject

Psoriasis

United Kingdom

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