Search clinical trials for: Apomine

Total 142 results

Genzyme, a Sanofi Company

Completed

SR-45023A in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Genzyme, a Sanofi Company

Completed

SR-45023A in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Genzyme, a Sanofi Company

Terminated

An Investigation Into the Short Term Effect of APOMINE in Patients With Osteoporosis or Low Bone Mass

Osteoporosis

United States
Bioglane

Completed

Effects of Added D-fagomine on Glycaemic Responses to Sucrose

Reduction of Post-prandial Glycaemic Response

United Kingdom
Bioglane
University Rovira i Virgili; National Research Council, Spain; Technological...

Completed

The Effects of D-Fagomine on Glycaemic Response to Sucrose in Men

Insulinemic Response | Glycaemic Response

Spain
Chang Gung Memorial Hospital

Unknown

Modified Suction-assisted Cartilage Shaver for Axillary Osmidrosis

Treatment Outcome | Axillary Odor, Variation in

Taiwan
Seoul National University Hospital

Withdrawn

Effect of Erythropoietin in Refractory Autoimmune Encephalitis Patients

Autoimmune Encephalitis

Korea, Republic of
Coordinación de Investigación en Salud, Mexico
Instituto Mexicano del Seguro Social; Universidad de Guanajuato

Completed

Effects of High vs. Standard Protein Intake in Newborn Extreme Premature (experimental)

Malnutrition | Abnormal Renal Function

Mexico
University of Pennsylvania

Recruiting

Molecular Imaging of the Underlying Mechanism of Cardiotoxicity in Patients With Light Chain Amyloidosis Using PET/CT

Cardiac Amyloidosis

United States
University of Pennsylvania

Active, not recruiting

Evaluation of Neuroinflammation in Parkinson's Disease Using 18F-NOS PET/CT

Parkinson Disease | Healthy Volunteer

United States
Yaakov Stern
National Institute on Aging (NIA)

Recruiting

Tau PET in Imaging and Cognition: Healthy Adults From 55-90

Aging | Mild Cognitive Impairment

United States
University of Pennsylvania

Recruiting

Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

Healthy Volunteer | Smoking, Cigarette | Smoking E-cigarette

United States
Jonsson Comprehensive Cancer Center

Terminated

Quantifying Oxygen Utilization of Tumors Using Oxygen-Enhanced Molecular MRI

Malignant Brain Neoplasm

United States
Washington University School of Medicine

Completed

iNOS With Positron Emission Tomography (PET) in Cellular Inflammation. (F-NOS)

Patients With Post Orthotopic Heart Transplantation Status

United States
University of Pennsylvania

Recruiting

Evaluation of Neuroinflammation FNOS PET/CT in HIV (+) and (-) Subjects With OUD and Healthy Controls

HIV Infections | Opioid Use

United States
Technische Universität Dresden
Colgate Palmolive

Completed

Effect of Toothpaste on the Reduction of Plaque and Inflammation

Gingivitis | Dental Plaque

Germany
Cairo University

Unknown

Color Stability of E.Max CAD Laminate Veneers Cemented With Light Cure Versus Dual Cure Amine Free Adhesive Resin Cement

Tooth Discoloration
Colgate Palmolive

Recruiting

Anti-gingivitis Mouthrinse

Gingivitis

Germany
Technische Universität Dresden
Gaba International AG

Completed

Effect of Mouthrinsing on Inflammation of the Gums.

Gingivitis

Germany
DH Bio Co., Ltd.
BTO Pharm. Co., Ltd.

Completed

Efficacy and Safety Study of Haporine-S for Treatment of Moderate to Severe Dry Eye Syndromes

Dry Eye Syndromes

Korea, Republic of
Suez Canal University

Completed

Complications of Ethanol-amine Oleate Intralesional Sclerotherapy

Venous Malformation

Egypt
Novartis

Completed

A Study of Three Doses of TCH346 in Patients With Early Parkinson's Disease to Evaluate Safety and Efficacy

Parkinson's Disease

United States, France, Germany, Portugal, Netherlands, United Kingdom, Italy, Canada, Brazil
Amgen

Completed

AMG 319 Lymphoid Malignancy FIH

Lymphoma | Leukemia | Cancer | Non-Hodgkin's Lymphoma | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Hematologic Malignancies | Diffuse Large Cell Lymphoma | Oncology | Tumors | T Cell Lymphoma | Oncology Patients | Hematology | Low Grade Lymphoma

United States
Cancer Research UK

Terminated

AMG 319 in HPV Positive and Negative HNSCC

Human Papillomavirus (HPV) | Positive or Negative Head and Neck Squamous Cell Carcinoma (HNSCC) of the Hypopharynx, Oropharynx, Oral Cavity, Supraglottis or Larynx

United Kingdom
Catholic University of the Sacred Heart

Completed

Physiological Effects of Lung Recruitment During General Anesthesia and Low-tidal Volume Ventilation (PEEP-RM)

Anesthesia, General | Surgery

Italy
Ain Shams University

Completed

A Clinical Study for the Effect of 4th Generation Poly AmidoAmine Dendrimer on Post-Bleaching Hypersensitivity and Shade Stability

Tooth Hypersensitivity

Egypt
Colgate Palmolive

Completed

A New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems

Plaque | Gum Disease

Italy
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacokinetics Study to Evaluate Safety and Tolerability of JNJ-37822681 in Participants With Stable Schizophrenia

Schizophrenia

Belgium, Germany, Russian Federation, Slovakia, Sweden
University of Zagreb
University of Split, School of Medicine

Recruiting

Assessment of the Cytotoxic and Genotoxic Effect of Toothpastes With Different Forms of Fluoride on the Buccal Mucosa

DNA Damage

Croatia
GlaxoSmithKline

Completed

In Situ Caries Model of Fluoride Toothpastes

Caries
Biogen

Completed

Dose-Finding Safety Study of BIIB014 in Early-Stage Parkinson's Disease (MOBILE)

Parkinson's Disease

Poland, Israel, Serbia
Biogen

Completed

BIIB014 Cardiovascular Monitoring Study

Healthy

United States
Biogen

Completed

Dose-Finding Safety Study of BIIB014 in Combination With Levodopa in Moderate to Late Stage Parkinson's Disease

Parkinson's Disease

United Kingdom, Israel, India
Biogen

Completed

Using PET Scans to Study Brain Receptor Occupancy of BIIB014 in Healthy Male Volunteers

Healthy

United Kingdom
University of Zurich

Completed

Investigation of Serotonin Neurotransmission in MDMA Users Using Combinated Dexfenfluramine Challenge and PET Imaging (DEXFEN_PET)

Amphetamine-Related Disorders | Amphetamine Abuse

Switzerland
Otsuka Pharmaceutical Co., Ltd.

Completed

A Multicenter Open-label Study Investigating the Pharmacokinetics and Safety of Aripiprazole IM Depot Formulation (OPC-14597 IMD) During Repeated Administration by Injection Into the Deltoid Muscle in Patients With Schizophrenia

Schizophrenia

Japan
Biogen

Withdrawn

BIIB014 Phase 2a Monotherapy

Parkinson's Disease
Biogen

Completed

BIIB014 Effects on the Pharmacokinetics (PK) of Rosiglitazone, Warfarin, and Midazolam

Healthy

United Kingdom
Johnson & Johnson Pharmaceutical Research & Development...

Completed

An Efficacy and Safety Study of 3 Fixed Doses of JNJ-37822681 in Participants With Schizophrenia

Schizophrenia

Taiwan, Malaysia, Romania, South Africa, Ukraine, Korea, Republic of, Russian Federation, Bulgaria, Lithuania, Estonia
University of Leeds

Completed

Total Salivary Fluoride Concentration of Healthy Adult Subjects Following Toothbrushing With Different Formulations of Fluoridated Toothpastes With and Without Post-brushing Water Rinsing.

Caries

United Kingdom
Prescient Therapeutics, Ltd.
National Cancer Institute (NCI)

Terminated

PTX-200, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide in Treating Patients With Stage IIB-IV Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Positive | HER2/Neu Negative | Breast Adenocarcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

Prognostic Stage IIIC Breast Cancer AJCC v8 | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Locally Advanced Malignant Solid Neoplasm | Locally... and other conditions

United States
Jaime Moore, MD MPH
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Completed

Adjunct Phentermine + Topiramate After Bariatric Surgery in 12-24 Year Olds

Adolescent | Obesity, Morbid | Drug Therapy | Bariatric Surgery | Young Adult

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia

Leukemia

United States, Canada
Roswell Park Cancer Institute
Iovance Biotherapeutics, Inc.

Withdrawn

Adoptive Cell Therapy With (LN-145) in Combination With Pembrolizumab in Treating Patients With Unresectable or Metastatic Transitional Cell Cancer Who Have Failed Cisplatin-Based Chemotherapy

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Unresectable Renal Pelvis Urothelial Carcinoma | Unresectable Ureter Urothelial Carcinoma

United States
Fred Hutchinson Cancer Center
HighPass Bio, Inc.

Suspended

HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Acute Myeloid Leukemia | Leukemia | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Chronic Myelomonocytic Leukemia | Recurrent Myelodysplastic Syndrome | Refractory... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI); Mustang Bio, Inc.

Active, not recruiting

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Refractory Acute Myeloid Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm | Minimal Residual Disease | Acute... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Ziopharm Oncology

Completed

CD19-Specific T-cells in Treating Patients With Advanced Lymphoid Malignancies

Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | Minimal Residual Disease | Small Lymphocytic Lymphoma | Acute Biphenotypic Leukemia | Stage III Chronic Lymphocytic Leukemia | Stage IV Chronic Lymphocytic Leukemia | CD19 Positive | Blasts 5 Percent or More of Bone Marrow Nucleated Cells

United States
Crystal Mackall, MD

Recruiting

Phase I Dose Escalation Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia | Philadelphia Chromosome Positive | Refractory Acute Lymphoblastic Leukemia | Minimal Residual Disease | CD19 Positive

United States
Crystal Mackall, MD
California Institute for Regenerative Medicine (CIRM)

Active, not recruiting

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells With or Without NKTR-255 in Adults With Recurrent or Refractory B Cell Malignancies

B Acute Lymphoblastic Leukemia | Philadelphia Chromosome Positive | Minimal Residual Disease | CD19 Positive

United States

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