Search clinical trials for: elamipretide (intermediate dose)

Total 6356 results

Stealth BioTherapeutics Inc.

Completed

Safety, Tolerability, and Efficacy of MTP-131 for the Treatment of Mitochondrial Myopathy (MMPOWER)

Mitochondrial Myopathy

United States
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Single Dose Tolerability and Pharmacokinetics of IBI112 in Healthy Subjects

Healthy Subjects

China
Pharnext SA

Completed

Phase II, Randomized, Placebo-controlled Trial in Patients With Charcot-marie-tooth Disease Type 1A

Charcot-Marie-Tooth Disease | Hereditary Neuropathy With Liability to Pressure Palsies | Genetic Disorders

France
Stealth BioTherapeutics Inc.

Completed

ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GA (ReCLAIM-2)

Age-related Macular Degeneration

United States
KBio Inc

Completed

Study to Evaluate the Safety and Immunogenicity of KBP-V001 Quadrivalent Influenza Vaccine in Healthy Adults

Influenza

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Netherlands Organisation for Scientific Research; Aspen Pharma; CHU of Saint... and other collaborators

Completed

Comparison of Low and Intermediate Dose Low-molecular-weight Heparin to Prevent Recurrent Venous Thromboembolism in Pregnancy (Highlow)

Pulmonary Embolism | Deep Venous Thrombosis

Norway, Netherlands, Denmark, France, Belgium, Ireland, United States, Canada, Russian Federation, Spain
Stealth BioTherapeutics Inc.

Recruiting

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD) (ReNEW)

Age-Related Macular Degeneration

United States
Stealth BioTherapeutics Inc.

Completed

A Phase 2 Study to Evaluate the Impact of MTP-131 (Bendavia™) on Skeletal Muscle Function in Elderly (MOTION)

Skeletal Muscle Mitochondrial Dysfunction in the Elderly

United States
Janssen Research & Development, LLC
Janssen Research & Development, LLC

Active, not recruiting

Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

X-Linked Retinitis Pigmentosa

United States, Canada, Israel, United Kingdom, Spain, Denmark, France, Belgium, Italy, Netherlands, Switzerland
Chiesi Farmaceutici S.p.A.

Active, not recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibody (mAb) in Patients With IPF

Idiopathic Pulmonary Fibrosis

North Macedonia, Ukraine, United Kingdom
Mashhad University of Medical Sciences

Unknown

Comparative Study of Different I-131 Doses in Graves' Disease

Graves' Disease

Iran, Islamic Republic of
Boehringer Ingelheim

Completed

Clinical Drug Trial in Healthy Male Subjects to Determine and Compare the Blood Concentrations of BI 144807 Following Administration as Oral Solution and Tablet Under Fasted and Fed Conditions

Healthy

Germany
University of Iowa

Completed

Covid-19 Associated Coagulopathy

COVID 19 Associated Coagulopathy

United States
Stealth BioTherapeutics Inc.

Terminated

Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)

Primary Mitochondrial Disease

United States
Stealth BioTherapeutics Inc.

Terminated

A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy Followed by Open-Label Extension (MMPOWER-3)

Primary Mitochondrial Myopathy

United States, Germany, Canada, Italy, United Kingdom, Denmark, Hungary
Stealth BioTherapeutics Inc.

Completed

Effect of Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Reduced Ejection Fraction

Heart Failure

Netherlands, Italy, United Kingdom
Stealth BioTherapeutics Inc.

Completed

A Phase 2 Study to Evaluate the Cardiac and Renal Effects of Short Term Treatment With Elamipretide in Patients Hospitalized With Congestion Due to Heart Failure

Heart Failure

Spain, Hungary, Netherlands, United Kingdom, Serbia, France, Latvia, Belgium, Bulgaria, Poland
Stealth BioTherapeutics Inc.

Completed

Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER Study (MMPOWER-2)

Primary Mitochondrial Disease

United States
Stealth BioTherapeutics Inc.
Charite University, Berlin, Germany; SCIRENT Clinical Research and Science...

Completed

A Study to Evaluate the Effects of 4 Weeks Treatment With Subcutaneous Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Preserved Ejection Fraction

Chronic Heart Failure

Germany, Serbia
Bioprojet

Completed

Randomized Clinical Trial Evaluating BP1.3656 Versus Placebo For Alcohol Use Disorder Treatment

Alcohol Use Disorder

France, Bulgaria, Russian Federation
Stealth BioTherapeutics Inc.

Completed

An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related Macular Degeneration

Age-Related Macular Degeneration

United States
Stealth BioTherapeutics Inc.

Available

An Intermediate Size Expanded Access Protocol of Elamipretide

Mitochondrial Diseases | Barth Syndrome
Stealth BioTherapeutics Inc.
ICON Clinical Research

Completed

Evaluation of Myocardial Effects of MTP-131 for Reducing Reperfusion Injury in Patients With Acute Coronary Events (EMBRACE)

Reperfusion Injury | STEMI

United States, Hungary, Germany, Poland
University Medical Center Groningen

Completed

Walking the Isobole of Drug Interaction (Walibi)

Anesthesia | Hemodynamic Instability | Interaction | Disorder of Oxygen Transport

Netherlands
Stealth BioTherapeutics Inc.

Completed

A Trial to Evaluate Safety, Tolerability and Efficacy of Elamipretide in Subjects With Barth Syndrome (TAZPOWER)

Barth Syndrome

United States
Allergy Therapeutics

Completed

Different Doses of Tyrosine Adsorbed Tree Pollen Allergoid With Monophosphoryl Lipid A (MPL) in Patients Sensitized to Tree Pollen

Type I Hypersensitivity

Canada
Taiho Pharmaceutical Co., Ltd.

Recruiting

A Study of TAS3731 in Healthy Adults

Healthy Adult Males

Japan
Maastricht University Medical Center

Unknown

Management and Outcomes of Anti-thrombotic Medication Use in Thrombocytopenia (MATTER)

Hematologic Neoplasms | Thrombocytopenia | Anticoagulants | Platelet Aggregation Inhibitors

Netherlands, Italy, Israel, United States
Children's Hospital of Philadelphia
Friedreich's Ataxia Research Alliance; Stealth BioTherapeutics Inc.

Active, not recruiting

FRDA Investigator Initiated Study (IIS) With Elamipretide (ELViS-FA)

Friedreich Ataxia

United States
Stealth BioTherapeutics Inc.

Terminated

Effects of Intravenous Bendavia™ on Reperfusion Injury in Patients Undergoing Angioplasty of the Renal Artery (EVOLVE)

Renal Artery Obstruction | Ischemia Reperfusion Injury | Hypertension, Renovascular

United States
Institute of Medical Biology, Chinese Academy of...
Guangxi Center for Disease Control and Prevention

Completed

Clinic Trial to Evaluate the Safety and Immunogenicity by Different Sequential Schedules of bOPV and IPV

Poliomyelitis

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Safety and Efficacy Study of SHR4640 and Febuxostat in Subjects With Hyperuricemia

Hyperuricemia
Seqirus
Department of Health and Human Services

Recruiting

Study to Evaluate Immunogenicity, Safety and Tolerability of Adjuvanted and Non-Adjuvanted H2N3 Influenza Vaccines in Adults

Infections | Virus Diseases | Respiratory Tract Infections | Influenza, Human | Infection Viral

Philippines, United States
Imperial College London
The Health Foundation

Completed

Assessment of the Effects of an Intermediate Care Package in Preventing Hospitalisation of Patients With COPD

COPD

United Kingdom
Henry Ford Health System

Completed

Comparison of Scar Results and Time for Closures of Scalp Defects Via Pulley Sutures or Layered Repairs

Scar

United States
University Hospitals, Leicester
Warwick Medical School

Completed

Evaluation of Intermediate Care Clinics for Diabetes (ICCD)

Type 2 Diabetes

United Kingdom
Galapagos NV

Completed

First-in-Human Single and Multiple Dose of GLPG2222

Healthy

Belgium
Rajaie Cardiovascular Medical and Research Center
Brigham and Women's Hospital; Tehran Heart Center; Imam Khomeini Hospital; Masih... and other collaborators

Completed

Intermediate-dose vs Standard Prophylactic Anticoagulation and Statin vs Placebo in ICU Patients With COVID-19 (INSPIRATION)

Covid19

Iran, Islamic Republic of
Boehringer Ingelheim

Completed

Safety And Efficacy of BIBF 1120 in Idiopathic Pulmonary Fibrosis

Pulmonary Fibrosis

Argentina, Australia, Belgium, Brazil, Bulgaria, Canada, Chile, China, Czech Republic, France, Germany, Greece, Hungary, Ireland, Italy, Korea, Republic of, Mexico, Netherlands, Portugal, Russian Federation, South Africa, Spain, Taiwan and more
Rigshospitalet, Denmark

Completed

The Effect of Frequency and Duration of Breaks in Sitting Time on Metabolic Cardiovascular Risk Factors (BPS2)

Sedentary Lifestyle | Overweight and Obesity | Metabolic Disease

Denmark
Stealth BioTherapeutics Inc.

Active, not recruiting

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) (NuPower)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism Defect

Spain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial Dystrophy (FCED) (SPIFD-101)

Fuchs' Corneal Endothelial Dystrophy (FCED)

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-42721458 in Healthy Male Participants

Healthy

Belgium
Mahidol University

Completed

The Feasibility of Bilateral Intermediate Cervical Plexus Block for Thyroidectomy/Parathyroidectomy

Thyroid Nodule | Parathyroid Adenoma

Thailand
Guangzhou Henovcom Bioscience Co. Ltd.

Completed

A Study of HNC042 in Healthy Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics.

Healthy

United States
Democritus University of Thrace

Unknown

Development of a Validated Chart for Intermediate Vision Assessment

Presbyopia | Astigmatism | Myopia | Hyperopia

Greece
Sichuan Haisco Pharmaceutical Group Co., Ltd

Completed

Safety, Tolerability and Pharmacokinetics of FTP-198 in Healthy Australian Volunteers

Healthy

Australia
GEN İlaç ve Sağlık Ürünleri A.Ş.
Sulfateq B.V.

Recruiting

A First-In-Human Study of Single and Multiple Ascending Doses of Oral SUL-238 in Healthy Subjects

Healthy Subjects

Turkey
Istanbul Medipol University Hospital

Completed

Examining The Effect of Chronotype Differences on Sleep Quality and Pregnancy Symptoms in Pregnant Women

Pregnancy Complications | Chronotype

Turkey
Enterprise Therapeutics Ltd

Completed

A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD001 in Healthy Subjects

Cystic Fibrosis

United Kingdom

Search clinical trials for: elamipretide (intermediate dose)

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