Search clinical trials for: midazolam / ketamine sublingual tablet

Total 263 results

Melt Pharmaceuticals
Catalent; Evolution Research Group; MedTrials Incorporated; Pharmalex

Recruiting

A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)

Cataract

United States
Vance Thompson Vision

Unknown

A Randomized, Double-Masked, Controlled, Single Site Investigator Initiated, Exploratory Study of the Midazolam/Ketamine Melt vs Ketamine Melt Alone vs Midazolam Melt Alone in Subjects Undergoing Intraocular Surgery. (MAKER)

Anesthesia

United States
Stallergenes Greer

Completed

Safety and Efficacy on Phase III Study on 300 IR SLIT to Patients Suffering From Grass Pollen Rhinoconjunctivitis

Primary Disease

France, Italy, Spain
Stallergenes Greer

Completed

Study of Efficacy and Safety of 300 IR Sublingual Immunotherapy (SLIT) Tablets in Adult Patients With Allergic Grass Pollen Rhinoconjunctivitis

Allergic Rhinitis Due to Grass Pollens

United States
Stallergenes Greer

Completed

Efficacy and Safety of 300 IR Sublingual Immunotherapy (SLIT) Tablets in Children Suffering From Grass Pollen Rhinoconjunctivitis

Allergy

Germany
ALK-Abelló A/S

Active, not recruiting

House Dust Mite Allergy Trial In Children (MATIC)

Allergic Rhinitis Due to Dermatophagoides Farinae | Allergic Rhinitis Due to Dermatophagoides Pteronyssinus | Allergic Rhinitis Due to House Dust Mite

Spain, Russian Federation, United States, Poland, Bulgaria, Canada, France, Germany, Lithuania, Slovakia, Ukraine
ALK-Abelló A/S

Terminated

A Research Study in Chinese People With Allergy to House Dust Mites, Using an Environmental Exposure Chamber (QUEST)

Allergic Rhinoconjunctivitis

Austria, China
Stallergenes Greer

Completed

Efficacy and Safety of Sublingual Tablets of Grass Pollen Allergen Extract

Seasonal Allergic Rhinitis

Austria
Bispebjerg Hospital
Lund University; University of Copenhagen; ALK-Abelló A/S

Completed

The Effect of Allergen Immunotherapy on Anti-viral Immunity in Patients With Allergic Asthma (VITAL)

Allergic Asthma Due to Dermatophagoides Pteronyssinus

Denmark
Beijing Tiantan Hospital
NeuroDawn Pharmaceutical Co., Ltd.

Recruiting

Cilostazol Dexborneol Versus Placebo for Microcirculation Dysfunction After Reperfusion Therapy in Patients With Acute Ischemic Stroke With Large Vessel Occlusion (CRYSTAL)

Acute Ischemic Stroke | Large Vessel Occlusion | Reperfusion

China
Simcere Pharmaceutical Co., Ltd

Completed

A Study to Evaluate the Pharmacokinetics,Safety and Tolerability of Y-2 Sublingual Tablet in Healthy Adult Subjects

Healthy

United States
Melt Pharmaceuticals
Worldwide Clinical Trials

Completed

Relative Bioavailability Study of MELT-100, IV Midazolam, and IV Ketamine

Procedural Sedation

United States
Stallergenes Greer
Quintiles, Inc.

Completed

Safety and Tolerability Study of Ragweed SLIT Tablets

Rhinitis, Allergic, Seasonal | Ragweed Pollen Allergy

Hungary
Stallergenes Greer

Completed

Dose Ranging Study of SLIT Tablets of House Dust Mite Allergen Extracts (HDM) in Adults With HDM-associated Allergic Asthma

Asthma | House Dust Mite Allergy

France, Germany, Poland
Tonix Pharmaceuticals, Inc.

Terminated

Repeat of: A Study to Evaluate Efficacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With Fibromyalgia (RE-AFFIRM)

Nervous System Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Muscular Diseases | Neuromuscular Diseases | Fibromyalgia | Myofascial Pain Syndromes

United States
Tonix Pharmaceuticals, Inc.

Completed

A Study to Evaluate eFFIcacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With fibRoMyalgia (AFFIRM)

Nervous System Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Muscular Diseases | Neuromuscular Diseases | Fibromyalgia | Myofascial Pain Syndromes

United States
Stallergenes Greer

Completed

Phase III Study to Assess the Long Term Efficacy, Carry-over Effect and Safety of 300 IR Sublingual Immunotherapy Tablets

Allergy

France
Stallergenes Greer

Completed

Safety and Efficacy Study of Sublingual Immunotherapy (SLIT) to Treat House Dust Mite Allergic Rhinitis

Allergic Rhinitis
Stallergenes Greer

Completed

Safety and Efficacy of Sublingual Immunotherapy (SLIT) Tablets in Grass Pollen Rhinoconjunctivitis

Allergy
Seoul National University

Withdrawn

Proportional Dose of Sublingual Fentanyl Tablet Based on Daily Opioid Requirement

Breakthrough Pain | Cancer Pain
EMS

Not yet recruiting

Safety and Efficacy of Zolpidem in the Long-Term Treatment of Insomnia

Chronic Insomnia

Brazil
University Hospital of Cologne

Completed

Tolerability of SLIT With LAIS® Mites Allergoid Tablets

Allergic Rhinitis
Tonix Pharmaceuticals, Inc.

Completed

A Study To Evaluate The Efficacy And Safety Of TNX-102 SL In Patients With Fibromyalgia (RELIEF)

Fibromyalgia

United States
Universidade Federal de Goias

Completed

Sevoflurane Associated With Oral Midazolam and Ketamine for Dental Sedation

Dental Anxiety

Brazil
Tonix Pharmaceuticals, Inc.

Completed

A Phase 3 Study To Evaluate The Efficacy And Safety Of TNX-102 SL In Patients With Fibromyalgia (RALLY)

Fibromyalgia

United States
Tonix Pharmaceuticals, Inc.
Premier Research Group plc

Terminated

Safety and Efficacy Study of TNX-102 SL in Patients With Military-related PTSD (HONOR)

PTSD

United States
HealthPartners Institute

Completed

Esophageal Food Impaction (ONEFIT)

Esophageal Food Bolus Obstruction

United States
Peking University Third Hospital

Completed

Phase III Clinical Trial of Y-2 Sublingual Tablets in the Treatment of Acute Ischemic Stroke

Stroke

China
Universidade Federal de Goias
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment (NASO)

Dental Caries | Child Behavior

Brazil
University of Chicago

Completed

The Effects of Buprenorphine on Responses to Verbal Tasks

Basic Science

United States
Second Affiliated Hospital of Wenzhou Medical University

Recruiting

Clinical Study of Oral Midazolam Combined With Esketamine Administered Intranasally for Pediatric Preoperative Sedation

Anxiety

China
Pfizer's Upjohn has merged with Mylan to form Viatris...

Withdrawn

Bioequivalence Of A Test Alprazolam Sublingual Formulation Compared To A Commercial Sublingual Formulation

Healthy
Titan Pharmaceuticals

Completed

A Study of Adult Outpatients With Opioid Dependence Transitioned From a Daily SL Buprenorphine to Probuphine® Subdermal Implants (PRO-814)

Opioid Dependence
National University of Malaysia

Recruiting

Ketamine-midazolam as a Sedative Agent in Endoscopic Retrograde Cholangiopancreatography.

Pancreatic Cancer | Cholangitis | Choledocholithiasis | Choledochal Cyst

Malaysia
Wake Forest University Health Sciences

Completed

Sedation Methods During Cataract Surgery

Cataract | Phacoemulsification
Tonix Pharmaceuticals, Inc.

Terminated

A Phase 3 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Participants With PTSD (RECOVERY)

PTSD

United States
Imperial College London
ALK-Abelló A/S

Unknown

Factors Predicting Efficacy of Allergen Injection Immunotherapy for Grass Pollen Hayfever

Rhinitis, Allergic, Seasonal

United Kingdom
Kanuni Sultan Suleyman Training and Research Hospital

Completed

A Comparison of the Sedation During Endoscopy in Children

Failed Moderate Sedation During Procedure
Universidad de Cartagena

Completed

Study of Comparison of the Effectiveness of Three Diagrams for Sedation in Spinal Anesthesia

Anesthesia; Reaction

Colombia
Psychiatric University Hospital, Zurich

Unknown

Transfer From Methadone to Buprenorphine Maintenance Treatment Using Buprenorphine Patches

Heroin Addiction

Switzerland
Tonix Pharmaceuticals, Inc.

Withdrawn

Safety and Efficacy Study of TNX-102 SL in Participants With PTSD

PTSD

Kenya
Orexo AB
Worldwide Clinical Trials

Completed

Multi-Center, Open-Label, 24-Week Study of OX219 Safety and Efficacy for Maintenance Treatment of Opioid Dependence

Opioid Dependence, on Agonist Therapy

United States
Futura Medical Developments Ltd.

Completed

Evaluating MED2005 & Nitrostat Bioavailability (FM58)

Erectile Dysfunction

United Kingdom
Wuhan Union Hospital, China

Recruiting

Esketamine Induction Intubation in ICU Patients.

Critically Ill Patients

China
University Hospital, Basel, Switzerland

Completed

The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal Midazolam (NASKEMI)

Spinal Stenosis | Analgesia, Patient-controlled

Switzerland
Tonix Pharmaceuticals, Inc.

Completed

BEdtime Sublingual TNX-102 SL as Fibromyalgia Intervention Therapy (BESTFIT) (BESTFIT)

Primary Fibromyalgia

United States
Universidad de Colima
Instituto Mexicano del Seguro Social

Recruiting

Ketamine vs Midazolam on Cognitive Function in Elderly in Elective Surgery Three-Months Postoperatively (ketaminvsMDZ) (ketaminvsMDZ)

Cognitive Dysfunction

Mexico
Kasr El Aini Hospital

Recruiting

Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events

Tonsillectomy | Adenoidectomy | Drug-Related Side Effects and Adverse Reaction

Egypt
Makerere University
THRiVE

Terminated

Comparing Clinical Outcomes Between Ketamine-midazolam and Morphine-midazolam for Continous Sedation in ICU Patients. (KeMiMof)

Critical Illness

Uganda
National Institute on Drug Dependence, China
Bronx VA Medical Center

Completed

Association of Functional COMT Val108/Met Polymorphism With Smoking Cessation in Nicotine Replacement Therapy

Nicotine Dependence

3

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