Search clinical trials for: midazolam and esketamine

Total 271486 results

Second Affiliated Hospital of Wenzhou Medical University

Recruiting

Clinical Study of Oral Midazolam Combined With Esketamine Administered Intranasally for Pediatric Preoperative Sedation

Anxiety

China
Wuhan Union Hospital, China

Recruiting

Esketamine Induction Intubation in ICU Patients.

Critically Ill Patients

China
National University of Malaysia

Recruiting

Ketamine-midazolam as a Sedative Agent in Endoscopic Retrograde Cholangiopancreatography.

Pancreatic Cancer | Cholangitis | Choledocholithiasis | Choledochal Cyst

Malaysia
University Hospital, Basel, Switzerland

Completed

The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal Midazolam (NASKEMI)

Spinal Stenosis | Analgesia, Patient-controlled

Switzerland
Wake Forest University Health Sciences

Completed

Sedation Methods During Cataract Surgery

Cataract | Phacoemulsification
Universidade Federal de Goias

Completed

Sevoflurane Associated With Oral Midazolam and Ketamine for Dental Sedation

Dental Anxiety

Brazil
Vance Thompson Vision

Unknown

A Randomized, Double-Masked, Controlled, Single Site Investigator Initiated, Exploratory Study of the Midazolam/Ketamine Melt vs Ketamine Melt Alone vs Midazolam Melt Alone in Subjects Undergoing Intraocular Surgery. (MAKER)

Anesthesia

United States
Erasmus Medical Center

Enrolling by invitation

Long-term Pain Modulation by Intravenous Esketamine in CRPS (KetCRPS-2)

Complex Regional Pain Syndromes | CRPS (Complex Regional Pain Syndromes)

Netherlands
Janssen Research & Development, LLC

Completed

Crossover Study to Evaluate the Abuse Potential of Intranasal Esketamine Compared to Racemic Intravenous Ketamine in Nondependent, Recreational Drug Users

Drug Abuse

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression (SYNAPSE)

Treatment Resistant Depressive Disorder

United States, Japan, Belgium
Universidad de Cartagena

Completed

Study of Comparison of the Effectiveness of Three Diagrams for Sedation in Spinal Anesthesia

Anesthesia; Reaction

Colombia
Medical University of Vienna

Recruiting

Imaging Neural Correlates of Ketamine Using PET/MR (RSKet)

Major Depressive Disorder

Austria
Kasr El Aini Hospital

Recruiting

Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events

Tonsillectomy | Adenoidectomy | Drug-Related Side Effects and Adverse Reaction

Egypt
Makerere University
THRiVE

Terminated

Comparing Clinical Outcomes Between Ketamine-midazolam and Morphine-midazolam for Continous Sedation in ICU Patients. (KeMiMof)

Critical Illness

Uganda
University of Ottawa
Canadian Institutes of Health Research (CIHR)

Completed

Action of Ketamine in Treatment-Resistant Depression

Treatment-resistant Depression

Canada
Soroka University Medical Center

Completed

The Efficacy of Midazolam & Ketamine Versus Midazolam & Fentanyl for Sedation in Ambulatory Colonoscopies

Colonoscopy | Conscious Sedation

Israel
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Bipolar Depression

Bipolar Depression

Poland
Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant Depression

Depression

Japan
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Depression

Major Depressive Disorder

Poland
Qinghai University
Qinghai Red Cross Hospital

Not yet recruiting

Effects of Esketamine on Postpartum Depression (EEPD)

Postpartum Depression
Fujian Provincial Hospital

Completed

Esketamine-propofol Versus Propofol for Flexible Bronchoscopy

Postoperative Recovery

China
Taipei Veterans General Hospital, Taiwan

Recruiting

Low-dose Ketamine Infusion Among Adolescents With Treatment-resistant Depression

Major Depressive Disorder | Treatment-resistant Depression

Taiwan
Universidad de Colima
Instituto Mexicano del Seguro Social

Recruiting

Ketamine vs Midazolam on Cognitive Function in Elderly in Elective Surgery Three-Months Postoperatively (ketaminvsMDZ) (ketaminvsMDZ)

Cognitive Dysfunction

Mexico
The George Institute
The University of New South Wales

Not yet recruiting

Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant Depression (TREK)

Treatment Resistant Depression

Australia
Dr. Inge Winter
Universität Münster

Recruiting

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (INTENSIFY MDD)

Major Depressive Disorder | Treatment Resistant Depression

Austria, Germany, Italy, Spain, United Kingdom
Universidade Federal de Goias
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment (NASO)

Dental Caries | Child Behavior

Brazil
Capital Medical University
The Second People's Hospital of Dali Bai Autonomous Prefecture; Wuhu Fourth... and other collaborators

Not yet recruiting

Esketamine Treatment for Depressive Episodes With Suicidal Ideation in Mood Disorders

Mood Disorders | Suicidal Ideation | Depressive Episode
Janssen Research & Development, LLC

Completed

A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant

United States
Alexandria University

Not yet recruiting

Propofol or Benzodiazepine Combined With Ketamine for Procedural Sedation in Emergency Setting

Procedural Sedation
New York State Psychiatric Institute

Terminated

Randomized Controlled Trial of Intranasal Ketamine vs. Intranasal Midazolam in Individuals With OCD

Obsessive-Compulsive Disorder

United States
Eye & ENT Hospital of Fudan University

Recruiting

Comparison of Esketamine-Propofol and Fentanyl-Propofol

Hemodynamics

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Intraoperative S-ketamine to Prevent Postoperative Hyperalgesia in Patients Undergoing Video-assisted Thoracic Surgery

Postoperative Hyperalgesia

China
Beijing Obstetrics and Gynecology Hospital
Obstetrics & Gynecology Hospital of Fudan University; Beijing Haidian Maternal... and other collaborators

Unknown

The Efficacy and Safety of S-ketamine in Elective Cesarean Section (ES-CS)

Depression | Analgesia | Cesarean Section | Anesthesia | Parturition
Janssen Research & Development, LLC

Completed

A Mass Balance Study With a Microtracer Dose of 14C-esketamine in Healthy Male Participants

Healthy

United States
Zylorion Health

Withdrawn

Repeated Intranasal Esketamine Plus Almond Therapy in Participants With Treatment Resistant Depressive Disorder - 3 Month Extension Study (ZYL-730-02)

Treatment Resistant Major Depressive Disorder
Tianjin Medical University General Hospital

Recruiting

S-ketamine Prevents Postoperative Pain and Cognitive Dysfunction After Tibial Fracture

Postoperative Pain | Postoperative Cognitive Dysfunction

China
Anqing Municipal Hospital

Completed

Esketamine Administration on Recovery Quality After Radical Mastectomy

Esketamine and the Quality of Recovery

China
Centre Hospitalier Universitaire de Charleroi
Centre Hospitalier Universitaire de Liege

Recruiting

Comparison of Ketamine and Esketamine in Patients Suffering From Fibromyalgia Syndrome. (KESK-FIQ)

Fibromyalgia

Belgium
Zylorion Health

Terminated

Repeated Intranasal Esketamine Plus Almond Therapy in Patients With Treatment Resistant Depression (ZYL-730-01)

Treatment Resistant Major Depressive Disorder

Canada
Janssen Research & Development, LLC

Completed

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

Depressive Disorder, Major

United States, France, Italy, Spain, Hungary, Belgium, Brazil, Bulgaria, Poland
Inonu University

Not yet recruiting

Dose Low Dose Ketamine in Casesarian

Postoperative Pain | Postpartum Depression

Turkey
Association pour la Formation l'Enseignement et...

Recruiting

Tolerance Assesment of the Usage of an Analgesic Dose of Esketamine for Treatment of Moderate to Intense Pain in an Emergency Departement (ESKETAMINE)

Pain, Acute

France
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Safety and Pharmacokinetic Study of Inhaled Esketamine in Healthy Volunteers

Healthy Volunteers

Poland
Complexo Hospitalario Universitario de A Coruña

Completed

Clinical Trial to Examine Individual Pain Tolerance in the Use of Two Anesthetic Techniques to Perform Saturation Prostate Biopsy

Prostatic Cancer

Spain
Abraham Nunes
Nova Scotia Health Authority

Recruiting

Predictors of Intravenous Ketamine Response in TRD

Bipolar Disorder | Major Depressive Disorder | Treatment Resistant Depression

Canada
Joshua Rosenblat

Recruiting

Ketamine for Treatment-Resistant Bipolar Disorder (KET-BD)

Bipolar Disorder | Bipolar Depression | Bipolar I Disorder | Bipolar II Disorder

Canada
Yale University
National Institute of Mental Health (NIMH)

Recruiting

Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous Ketamine

Adolescent Depression | Adolescent Suicide

United States
VA Office of Research and Development
Mayo Clinic; University of Minnesota

Completed

Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression

Treatment-resistant Depression

United States
Melt Pharmaceuticals
Worldwide Clinical Trials

Completed

Relative Bioavailability Study of MELT-100, IV Midazolam, and IV Ketamine

Procedural Sedation

United States
Tel-Aviv Sourasky Medical Center

Completed

Procedural Sedation Using Propofol Versus Midazolam/Ketamine in the Adult Emergency Department

Procedural Sedation

Israel

Search clinical trials for: midazolam and esketamine

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