Search clinical trials for: simvastatin and ezetimibe

Total 270460 results

Judit Pich

Completed

Efficacy of the Combination of Simvastatin Plus Rifaximin in Patients With Decompensated Cirrhosis to Prevent ACLF Development (2018-001698-25)

Liver Cirrhoses

Belgium, Spain, United Kingdom, Italy, Netherlands, France, Germany
Rockefeller University
Cornell University; Adelphi University

Terminated

Quality of Life in Patients With Statin-Associated Myopathy

Statin Adverse Reaction

United States
Medical University of Vienna

Unknown

Effects of Nicotinic Acid Plus Simvastatin Versus Simvastatin Alone on Carotid and Femoral Intima-Media Thickness in Patients With Peripheral Artery Disease (NASCIT) (NASCIT)

Atherosclerosis | Dyslipidemia

Austria
University of Pavia

Unknown

Losartan and Simvastatin in Hypertensive Obeses With Liver Steatosis

Hypertension

Italy
Seoul National University Hospital
Gangnam Severance Hospital

Recruiting

Efficacy and Safety of EzetimiBe/Rosuvastatin in Diabetic Dislipidemia With Hypertriglyceridaemia (REMBRANDT)

Diabetes Mellitus, Type 2 | Endocrine System Diseases | Dyslipidemias | Nutritional and Metabolic Diseases

Korea, Republic of
Organon and Co

Completed

An Efficacy and Safety Study of Ezetimibe (MK-0653, SCH 58235) in Addition to Atorvastatin Compared to Placebo in Participants With Primary Hypercholesterolemia (MK-0653-013)

Hypercholesterolemia
Odense University Hospital

Completed

Ezetimibe In Addition To Atorvastatin Therapy On The Plaque Composition In Patients With Acute Myocardial Infarction. (OCTIVUS)

ST-Segment Elevation Myocardial Infarction

Denmark
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-3 (GAUSS-3)

Hyperlipidemia

Canada, Denmark, France, United States, Czechia, New Zealand, Australia, South Africa, Italy, United Kingdom, Netherlands, Germany, Norway
Boehringer Ingelheim

Completed

Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Empagliflozin in Chinese Female and Male Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

China
Yonsei University

Completed

Effect of Lipid Modifying Drugs on HDL Function in Patients With Hyperlipidemia

Hyperlipidemia

Korea, Republic of
Organon and Co
Merck Sharp & Dohme LLC

Completed

Ezetimibe Plus Atorvastatin Versus Atorvastatin Alone in Subjects With Primary Hypercholesterolemia (Study P03406)

Atherosclerosis | Hypercholesterolemia
Organon and Co
Merck Frosst Canada Ltd.

Terminated

Ezetimibe Plus Simvastatin Versus Simvastatin in Patients With Hypercholesterolemia and Coronary Risk Factors (P03405)

Atherosclerosis | Hypercholesterolemia
National Heart, Lung, and Blood Institute (NHLBI)

Completed

SCH-58235 (Ezetimibe) to Treat Homozygous Sitosterolemia

Lipoidosis

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety Study of MCI-196 Versus Simvastatin for Dyslipidaemia in Chronic Kidney Disease (CKD) Subjects on Dialysis

Chronic Kidney Disease

Belarus, Bulgaria, Romania, Malaysia, Singapore, Thailand, Italy, Lithuania, Latvia, Croatia, Denmark, Israel, Indonesia
University of Cologne
German Federal Ministry of Education and Research

Completed

Statin Recapture Therapy Before Coronary Artery Bypass Grafting (StaRT-CABG)

Coronary Artery Disease

Germany
Hamamatsu University

Completed

Effects of Statins on the Pharmacokinetics for Midazolam in Healthy Volunteers (H-17-21)

Healthy Volunteers

Japan
Angiogenix

Unknown

Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease

Peripheral Arterial Disease | Intermittent Claudication

Russian Federation
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

HDL-Atherosclerosis Treatment Study (HATS)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease
Brigham and Women's Hospital

Unknown

The Effect of Providing Free Samples of Generic Cardiovascular Medications to Physicians (SAMPLES)

Hypertension | Hyperlipidemia

United States
Takeda

Completed

Determination of the Minimal Clinically Important Difference After Treatment With Pantoprazole in Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-340)

Gastroesophageal Reflux

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Pantoprazole in Neonates and Preterm Infants With GERD

Gastroesophageal Reflux

Belgium, Italy, United States, Australia, Canada, France, Germany, Netherlands, Poland, South Africa, Switzerland
Takeda

Completed

Efficacy of Pantoprazole in Patients Older Than 18 Years Who Have Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-339)

Gastroesophageal Reflux

Hungary, Austria, Germany, Poland
Takeda

Completed

Effect of Pantoprazole on the Symptoms of Acid Reflux Disease in Adult Patients (BY1023/M3-341)

Gastroesophageal Reflux Disease (GERD)

United Kingdom, Australia, Belgium, Spain, Austria, Germany, Argentina, Brazil, Canada, France, Hong Kong, India, Italy, Korea, Republic of, Malaysia, Mexico, Poland, Portugal, Singapore, South Africa, Switzerland, Taiwan
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-C

Hypercholesterolemia

United States
Organon and Co

Completed

A Study of the Effect of Ezetimibe on Glucose Metabolism in Type 2 Diabetics With Hypercholesterolemia (P06541)

Hypercholesterolemia
Organon and Co

Completed

Observational Study of Approaches to Lipid-Lowering Therapy in Russian Patients With Coronary Heart Disease <<Treat to Goal>> (Study P05464)

Hypercholesterolemia | Coronary Heart Disease
Policlinico Casilino ASL RMB
IRCCS San Raffaele

Unknown

Evolocumab Plus Ezetimibe in High Risk Haemodialized Statin Intolerant Patients

Hypercholesterolemia | Chronic Kidney Disease Requiring Chronic Dialysis

Italy
Laval University

Completed

Effects of Selective Inhibition of Cholesterol Absorption With Ezetimibe on Intestinal Cholesterol Homeostasis in Dyslipidemic Men With Insulin-resistance - a Pilot Study (EZEmRNA)

Metabolic Syndrome X

Canada
Boehringer Ingelheim

Completed

A Study to Determine Acute (After First Dose) and Chronic (After 28 Days) Effects of Empagliflozin (BI 10773) on Pre and Postprandial Glucose Homeostasis in Patients With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus and Healthy Subjects

Diabetes Mellitus, Type 2

Austria, Germany, Italy
Addpharma Inc.

Completed

Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan

Hypertension | Hypercholesterolemia

Korea, Republic of
Esperion Therapeutics, Inc.

Completed

A Study Evaluating the Safety and Efficacy of Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo in Patients Treated With Maximally Tolerated Statin Therapy

Hyperlipidemias

United States
LG Chem

Completed

Evaluating a Pharmacokinetic Drug Interaction Between LGEV1801 and LGEV1802

Healthy Male Volunteers

Korea, Republic of
Hospital Israelita Albert Einstein
Novartis; epHealth

Completed

Real World Evidence Study of Statin Use in Brazil (RWE-Statins)

Myocardial Infarction | Cardiovascular Diseases | Stroke | Hypertension | Diabetes Mellitus | Dyslipidemias

Brazil
Ahmed Mohamed Mahrous
University of Iowa; Greater New York Academy of Prosthodontics; American College...

Completed

Use of Topical Subgingival Application of Simvastatin Gel in the Treatment of Peri-Implant Mucositis

Peri-implant Mucositis

United States
Esperion Therapeutics, Inc.

Recruiting

Milk-Only Lactation Study to Evaluate the Concentration of Bempedoic Acid and Bempedoic Acid/Ezetimibe Fixed Combination Drug Product (FCDP) in the Breast Milk of Healthy Lactating Women

Healthy Lactating Women

United States
Pfizer

Completed

Dose Ranging Study Of Bococizumab (PF-04950615; RN316) In Hypercholesterolemic Japanese Subjects

Hypercholesterolemia

Japan
Sorlandet Hospital HF
Oslo University Hospital

Completed

Risk Reduction in Coronary Heart Disease (SPREK!)

Coronary Heart Disease

Norway
AstraZeneca

Active, not recruiting

Study to Assess the Effect of AZD9291 on the Blood Levels of Simvastatin in Patients With EGFRm+ NSCLC

Non Small Cell Lung Cancer

Belgium, Korea, Republic of, Spain, United States, France
National Institute of Diabetes and Digestive and...

Completed

The Use of Oral Omeprazole and Intravenous Pantoprazole in Patients With Hypersecretion of Gastric Acid

Gastrinoma | Zollinger Ellison Syndrome

United States
Federal University of São Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Unknown

Role of Immune Responses After Acute Myocardial Infarction (BATTLE-AMI)

Myocardial Fibrosis

Brazil
Merck Sharp & Dohme LLC

Terminated

A Study of the Efficacy and Safety of MK-0431D (a Fixed-dose Combination of Sitagliptin and Simvastatin) for the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-266)

Type 2 Diabetes Mellitus
Jena University Hospital

Not yet recruiting

Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target) (GoT)

ST Elevation Myocardial Infarction | Non-ST Elevation Myocardial Infarction | LDL-cholesterol

Germany
Chinese University of Hong Kong

Completed

The Interaction of Herbs and Statins

Drug Interaction

Hong Kong
Beersheva Mental Health Center

Withdrawn

Bexarotene and Fenretinide as Addition to Antipsychotic Treatment in Schizophrenia Patients

Schizophrenia | Schizoaffective Disorder | Cognition

Israel
Mayo Clinic

Completed

Renal Hemodynamic Effects of the HMG-CoA Reductase Inhibitors in Normal Volunteers and in Patients With Chronic Renal Failure

Hypertension | Hyperlipidemia | Chronic Renal Failure
University of Texas Southwestern Medical Center
Abhimanyu Garg; Prishant Mishra; Jimin Ren

Completed

7 Tesla MRI Study in Patients With Statin Related Muscle Complaints

Muscle Weakness | Muscle Cramp | Muscle Stiffness | Statin-related Muscle Pain | Muscle Aches

United States
Ain Shams University

Completed

Effect of Statin Therapy on Mortality in Patients With Ventilator Associated Pneumonia

VAP - Ventilator Associated Pneumonia

Egypt
University of Zurich
Stanford University

Terminated

Study for Identifying Optimal Simvastatin Formulation for Uniform Time to Maximum Plasma Concentration

Celiac Disease

Switzerland
Samsung Medical Center

Unknown

Trial of XELIRI/FOLFIRI + Simvastatin Followed by Simvastatin Maintenance in Metastatic Colorectal Cancer

Colorectal Cancer

Korea, Republic of
All India Institute of Medical Sciences, New Delhi
University of Zurich

Completed

Protocol for Correlating Enteropathic Severity and Small Intestinal CYP3A4 Activity in Patients With Celiac Disease (Cyp)

Celiac Disease

India

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