Search clinical trials for: Antifungal prophylaxis

Total 5895 results

University of Rome Tor Vergata

Recruiting

Role of Antifungal Prophylaxis in Elderly Patients With Acute Myeloid Leukemia During Consolidation Therapy

Invasive Aspergillosis

Italy
University Hospital, Toulouse

Not yet recruiting

Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis (RAPA-4-PAF)

Familial Adenomatous Polyposis

France
Peking University People's Hospital

Not yet recruiting

Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors

Myelodysplastic Syndromes | Acute Leukemia | Severe Aplastic Anemia
St. Jude Children's Research Hospital

Recruiting

A Phase II Pediatric Study of a Graft-VS.-Host Disease (GVHD) Prophylaxis Regimen With no Calcineurin Inhibitors After Day +60 Post First Allogeneic Hematopoietic Cell Transplant for Hematological Malignancies

Hematologic Malignancy | Myeloid Malignancy

United States
National Cancer Institute (NCI)

Recruiting

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Peripheral Blood Stem Cell Transplantation

United States
The First Affiliated Hospital of Soochow University
The First Affiliated Hospital with Nanjing Medical University; Shenzhen People... and other collaborators

Recruiting

Sitagliptin for Prevention of aGVHD After Alternative Donor Transplantation

Allogeneic Hematopoietic Stem Cell Transplantation | Acute-graft-versus-host Disease

China
MEDSI Clinical Hospital 1, ICU

Recruiting

Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant Bacteria

Respiratory Tract Infections | Pneumonia | Sepsis | Critical Illness | Respiratory Distress Syndrome | Pneumonia, Ventilator-Associated | Bloodstream Infection

Russian Federation
Hospital Universitario Dr. Jose E. Gonzalez

Recruiting

Cyclosporine on Day Zero as Prophylaxis for Cytokine Release Syndrome

Cytokine Release Syndrome | Stem Cell Transplant Complications

Mexico
Institute of Hematology & Blood Diseases Hospital
The Second Hospital of Hebei Medical University; Tianjin Medical University... and other collaborators

Not yet recruiting

Posaconazole for Pulmonary Fungal Infection Prophylaxis in Hematopoietic Stem Cell Transplantation Patients

Pulmonary Fungal Infection

China
Cidara Therapeutics Inc.

Recruiting

Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation (ReSPECT)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis | Invasive Fungal Disease | Pneumocystis | Mold Infection | Prophylaxis of Invasive Fungal Infections | Aspergillus

United States, Germany, France, Belgium, Canada, Italy, Spain, United Kingdom, Turkey, Switzerland
Shanghai Jiao Tong University School of Medicine

Recruiting

Escalation Antifungal Prophylaxis for Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Fungal Infection

China
Bochud Pierre-Yves
Swiss National Science Foundation

Recruiting

PTX3-targeted Antifungal Prophylaxis (PTX3AML)

Acute Myeloid Leukemia | Candidiasis | Fungal Infection | Aspergillosis | Genetic Predisposition

Belgium, Switzerland, France
Melbourne Health
Merck Sharp & Dohme LLC

Recruiting

Posaconazole Pharmacokinetics in Patients Receiving Chemotherapy or Stem Cell Transplants (POPULAR)

Fungal Infection | Pharmacokinetics | Invasive Aspergillosis | Prophylaxis | Invasive Candidiases | Posaconazole | Invasive Mycosis

Australia
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation

Diffuse Large B-Cell Lymphoma | Acute Myeloid Leukemia | Recurrent Hodgkin Lymphoma | Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Recurrent Small Lymphocytic Lymphoma | Blastic Plasmacytoid Dendritic Cell Neoplasm | Prolymphocytic Leukemia and other conditions

United States
University Hospital, Angers

Recruiting

Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR (BIG-1)

Acute Myeloid Leukemia (AML)

France
Monica Bhatia

Completed

Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease

Sickle Cell Disease | Graft Versus Host Disease

United States
Ipsen

Active, not recruiting

Effects of Triptorelin When Given Every 6-months Under the Skin to Adult Males With Cancer in the Prostate (TriptoSwitch)

Prostate Cancer

Spain, Lithuania, Germany, France, Belgium, Netherlands, Czechia
University of Liege
University Hospital, Gasthuisberg; University Hospital, Ghent; University Hospital... and other collaborators

Active, not recruiting

Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis Regimens

Hematological Malignancies | Graft-Versus-Host Disease

Belgium
Seoul National University Hospital
Merck Sharp & Dohme LLC

Completed

Posaconazole Prophylaxis During ATG Treatment for hMDS/AA Patients

Myelodysplastic Syndromes | Fungal Infection | Aplastic Anemia

Korea, Republic of
Fundación Pública Andaluza para la gestión de la...

Active, not recruiting

Ixazomib in the Prophylaxis of Chronic Graft-versus-host Disease.

Multiple Myeloma | Hematopoietic Stem Cell Transplantation

Spain
Medical University of Graz
Merck Sharp & Dohme LLC

Completed

Posaconazole Prophylaxis for CAPA Prevention in Critically-Ill Patients (POSACOVID)

Aspergillosis | COVID-19 Respiratory Infection

Austria, France, Italy
Basilea Pharmaceutica

Completed

Safety, Efficacy and Pharmacokinetics of an Antifungal in Patients Undergoing Chemotherapy

Acute Myeloid Leukemia

Germany
Ciceri Fabio

Completed

Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic Syndrome and Acute Leukemia Under Primary Prophylaxis With Posaconazole (SIR-POSA)

Myelodysplastic Syndromes | Fungal Infection | Graft Vs Host Disease | Leukemia, Acute | Transplant-Related Hematologic Malignancy

Italy
Memorial Sloan Kettering Cancer Center
Astellas Pharma US, Inc.

Completed

Fungal Prophylaxis With Isavuconazole for Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant (HCT)

Hematologic Malignancy | Myeloproliferative Disorder

United States
Seoul National University Hospital
Astellas Pharma Inc

Completed

Micafungin Prophylaxis During 1st Induction Chemotherapy for De Novo Acute Leukemia

Acute Leukemia
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized, Comparative Study of Daily Dapsone and Daily Atovaquone for Prophylaxis Against PCP in HIV-Infected Patients Who Are Intolerant of Trimethoprim and/or Sulfonamides

HIV Infections | Pneumonia, Pneumocystis Carinii

United States, Tanzania
National Institute of Allergy and Infectious Diseases...
Pfizer

Completed

A Randomized, Prospective, Double-Blind Study Comparing Fluconazole With Placebo for Primary and Secondary Prophylaxis of Mucosal Candidiasis in HIV-Infected Women

HIV Infections | Candidiasis | Candidiasis, Esophageal

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT)

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Stanford University

Completed

Sirolimus & Mycophenolate Mofetil as GVHD Prophylaxis in Myeloablative, Matched Related Donor HCT

Lymphoma, Non-Hodgkin | Hematologic Diseases | Leukemia | Acute GVHD

United States
Pfizer

Completed

Diflucan Research For Infant Evaluation Of Antifungal Treatment And Prophylaxis Medication (DREAM)

Deep Mycosis
Fred Hutchinson Cancer Center

Withdrawn

Comparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell Transplantation

Recurrent Hodgkin Lymphoma | Myelofibrosis | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Hematopoietic and Lymphoid System Neoplasm | Recurrent... and other conditions

United States
Centre Hospitalier Universitaire Vaudois

Unknown

Breakthrough Invasive Mold Infections Under Posaconazole Prophylaxis (BIMI) (BIMI)

Hematologic Diseases | Hematologic Malignancy | Invasive Mold Infections | Breakthrough Invasive Mold Infections

Switzerland, Austria, Germany
Sir Ganga Ram Hospital

Completed

Helicobacter Pylori Eradication in Functional Dyspepsia

Dyspepsia | Helicobacter Pylori Infection

India
Radboud University Medical Center

Completed

Pharmacokinetics of Anidulafungin (Ecalta ®) Intravenous Given to Patients at High Risk for Developing Invasive Fungal Disease (ANIDULAPK)

Leukemia | Leukemia, Myeloid, Acute | Myelodysplastic Syndrome

Netherlands
Radboud University Medical Center

Completed

Pharmacokinetics of Fluconazole IV as Prophylaxis or Therapy to ICU Patients (PACIFIC)

Candidiasis

Netherlands
Radboud University Medical Center

Completed

Anidulafungin Pharmacokinetics Given as a Single Intravenous Dose to Obese Patients (ADOPT) (ADOPT)

Obesity Morbid

Netherlands
Radboud University Medical Center

Completed

Pharmacokinetics of Posaconazole in Children With Chronic Granulomatous Disease (CGD) (iPOD)

Chronic Granulomatous Disease

Netherlands
Assistance Publique - Hôpitaux de Paris

Completed

Cyclophosphamide Versus Anti-thymocyte Globulin for GVHD Prophylaxis After RIC Allo-SCT (ATG-CyGVHD)

Graft vs Host Disease

France
Peter MacCallum Cancer Centre, Australia
Merck Sharp & Dohme LLC

Unknown

Invasive Fungal Infections in Patients Following Stem Cell Transplant

Invasive Fungal Infections | Stem Cell Transplant Complications

Australia
National Cancer Institute (NCI)

Terminated

Pilot Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Matched Unrelated Double Cord Blood Transplant for the Treatment of Leukemias, Lymphomas, and Pre-Malignant Blood Disorders

Leukemia | Multiple Myeloma | MDS | Non-Hodgkins Lymphoma | Hodgkins Lymphoma

United States
Radboud University Medical Center
Universitaire Ziekenhuizen KU Leuven

Completed

Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal Infections (PIRAÑA)

Acute Graft Versus Host Disease | Allogeneic Stem Cell Transplant | Acute Myeloid Leucaemia | Myelo Dysplastic Syndrome

Belgium, Netherlands
Nanfang Hospital of Southern Medical University

Unknown

PTCy-ATG vs ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis

Hematopoietic Stem Cell Transplantation

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Diffuse Large B-Cell Lymphoma | Acute Myeloid Leukemia | Refractory Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Acute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Prolymphocytic Leukemia | Refractory... and other conditions

United States, Germany, Denmark
Regimmune Corporation

Completed

Intravenous Administration of RGI-2001 in Patient Undergoing Allogenic Hematopoietic Stem Cell Transplantation (AHSCT)

Graft Versus Host Disease

United States
Astellas Pharma S.A.S.

Completed

Use of Micafungin (Mycamine®) as Antifungal Prophylaxis in Haematology and Onco-haematology (OLYMPE)

Antifungal Prophylaxis | Haemopathy

France
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Terminated

Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Astellas Pharma Inc

Completed

Liver Transplant European Study Into the Prevention of Fungal Infection (TENPIN)

Liver Transplantation | Mycoses

Belgium, France, Italy, Spain, Ireland, Germany, Portugal, Saudi Arabia, Austria, United Kingdom, Russian Federation, Hungary, Sweden, Romania
Matinas BioPharma Nanotechnologies, Inc.
University of Cologne; The Clinical Trials Centre Cologne

Withdrawn

Safety and PK of Oral Encochleated Amphotericin B (CAMB/MAT2203) for Antifungal Prophylaxis in Patients Undergoing Induction Chemotherapy for Acute Myelogenous and Lymphoblastic Leukaemia

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight

Candidiasis

United States
M.D. Anderson Cancer Center
Schering-Plough

Completed

Pharmacokinetics of Posaconazole Prophylaxis in Acute Leukemia

Leukemia | Fungal Infection

United States

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