Search clinical trials for: Checkpoint kinase 1 CHK1

Total 57668 results

Eli Lilly and Company

Completed

A Study of Prexasertib (LY2606368) in Japanese Participants With Advanced Cancers

Neoplasm

Japan
Eli Lilly and Company

Completed

A Study of Prexasertib (LY2606368) in Participants With Extensive Stage Disease Small Cell Lung Cancer

Small Cell Lung Cancer

Spain, United States, Germany, Ukraine, France, Greece, Turkey, Netherlands, United Kingdom, Korea, Republic of
Boundless Bio

Recruiting

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), in Subjects With Tumors With Oncogene Amplifications (POTENTIATE)

Breast Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Bladder Cancer | Endometrial Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Liposarcoma | Non-Small Cell Squamous Lung Cancer | Non-Small Cell Lung Adenocarcinoma

United States
Actuate Therapeutics Inc.

Recruiting

9-ING-41 in Pediatric Patients With Refractory Malignancies.

Neuroblastoma | Pediatric Cancer | Diffuse Intrinsic Pontine Glioma | Pediatric Brain Tumor | Refractory Cancer | Refractory Neoplasm | Refractory Tumor | Cancer Pediatric | Neuroblastoma Recurrent | Pediatric Lymphoma | Pediatric Meningioma

United States
Ankara Yildirim Beyazıt University

Recruiting

Investigation of the Effects of Robot Assisted Gait Training With Virtual Reality on Cognitive Functions in Stroke Patients

Stroke | Exoskeleton Device | Locomotion

Turkey
Dana-Farber Cancer Institute
Eli Lilly and Company

Terminated

Prexasertib in Combination With MEC in Relapsed/Refractory AML and High Risk MDS - a Phase I Trial

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
Dana-Farber Cancer Institute
Eli Lilly and Company

Completed

A Study of Prexasertib (LY2606368), CHK1 Inhibitor, and LY3300054, PD-L1 Inhibitor, in Patients With Advanced Solid Tumors

Cancer

United States
Merck Sharp & Dohme LLC

Recruiting

Sacituzumab Tirumotecan (MK-2870) as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-2870-008)

Non-small Cell Lung Cancer | Solid Tumors | Programmed Cell Death-1 (PD1, PD-1) | Programmed Cell Death 1 Ligand 1(PDL1, PD-L1) | Programmed Cell Death 1 Ligand 2 (PDL2, PD-L2)

Japan
University of Liege

Unknown

Light Therapy in Disorders of Consciousness: Behavioral, Neuroimaging and (Neuro)Physiological Assessments.

Disorder of Consciousness
Shimousa Hematology Study Group
Epidemiological and Clinical Research Information Network

Unknown

Discontinuation of Dasatinib in Patients With Chronic Myeloid Leukemia-CP Who Have Maintained Complete Molecular Remission for Two Years; Dasatinib Stop Trial

Chronic Myeloid Leukemia

Japan
Tianjin Medical University Cancer Institute and...

Recruiting

Study of Neoadjuvant Endocrine Therapy in HR Positive and HER2 Negative Premenopausal Breast Cancer Patients

Breast Cancer

China
Hasan Kalyoncu University

Recruiting

Study of the Effect of Compassion-Based Education Program Applied to Mothers of Children Diagnosed With Cerebral Palsy

Cerebral Palsy

Turkey
EZUS-LYON 1

Active, not recruiting

CARdioprotection in Myocardial Infarction (CARIM)

Myocardial Infarct

France
EZUS-LYON 1

Active, not recruiting

The Influence of Manual Therapy Applied to the Cervical Spine in the Prevention of Balance Disorders in the Elderly (ManEq)

Elderly | Gait | Balance, Postural

France
Suleyman Demirel University

Recruiting

Developing a New Scale for Evaluating Shoulder Problems

Shoulder Injuries | Shoulder Pain | Shoulder Lesions

Turkey
Uro-1 Medical

Recruiting

Use of Repris Needle in Bladder Injection

Overactive Bladder Syndrome

United States
Uro-1 Medical

Recruiting

Assessment of VMCore Biopsy Versus Standard of Care Biopsy

Prostate Cancer

United States
Alpha-1 Foundation

Recruiting

Alpha-1 Research Registry

Alpha 1-Antitrypsin Deficiency

United States
Sierra Oncology LLC - a GSK company

Completed

A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects

Advanced Solid Tumors

Spain, United Kingdom
Actuate Therapeutics Inc.

Active, not recruiting

9-ING-41 in Patients With Advanced Cancers

Sarcoma | Cancer | Breast Neoplasms | Neoplasm Metastasis | Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Bone Cancer | Malignant Glioma | Bone Metastases | Pancreas Cancer | Renal Cancer | Refractory Non-Hodgkin Lymphoma | Bone Neoplasm | Neoplasm, Breast | Refractory Cancer | Refractory Neoplasm | Resistant... and other conditions

United States, Belgium, Canada, Spain, France, Netherlands, Portugal
Uro-1 Medical

Not yet recruiting

Evaluation of a Soft Tissue Biopsy System for Trans-rectal and Trans-perineal Biopsy of the Prostate

Prostate Disease
Children's Hospital 1

Recruiting

Sutureless Closure for Primary Total Anomalous Pulmonary Venous Connection (TAPVC)

Total Anomalous Pulmonary Venous Connection | Pulmonary Venous Stenosis | Sutureless Closure

Vietnam
Alpha-1 Foundation

Completed

Prevalence of Alpha-1 Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease (COPD) (PFT)

Chronic Obstructive Pulmonary Disease | Alpha-1 Antitrypsin Deficiency

United States, Puerto Rico
Kitasato University
Yokohama City University Medical Center; St. Marianna University School of... and other collaborators

Unknown

Intensive Medical Treatment for Nephropathy Caused by Type 2 Diabetes With Hypertension

Hypertension | Type 2 Diabetes Mellitus

Japan
OSCAR Study
Japan Heart Foundation

Completed

OlmeSartan and Calcium Antagonists Randomized (OSCAR) Study

Cardiovascular Diseases | Hypertension

Japan
Taiho Pharmaceutical Co., Ltd.

Completed

Randomized Phase III Study of TS-1 Alone Versus TS-1 Plus CDDP in Advanced Gastric Cancer

Gastric Cancer

Japan
Eastern Mediterranean University

Not yet recruiting

The Effect of Health Education and Yoga on Menopause Symptoms and Quality of Life According to Pender's Model

Quality of Life | Health Education | Yoga | Menopause Symptoms

Cyprus
Eastern Mediterranean University

Not yet recruiting

Effect of Acupressure on Pain, Anxiety and Vital Signs in Patients With Coronary Angiography

Pain | Anxiety | Coronary Angiography | Vital Signs

Cyprus
Cairo University

Unknown

Clinical Evaluation of Pink Esthetic Score

Thin Gingiva
The N.1 Institute for Health (N.1)
Acceset

Completed

A Study Protocol on Peer Digital Acceset (PDA) (PDA)

Mental Health Issue

Singapore
MEDSI Clinical Hospital 1, ICU

Recruiting

Efficacy and Safety of Selective Digestive Decontamination in the ICU With High Rates of Antibiotic-resistant Bacteria

Respiratory Tract Infections | Pneumonia | Sepsis | Critical Illness | Respiratory Distress Syndrome | Pneumonia, Ventilator-Associated | Bloodstream Infection

Russian Federation
Taiho Pharmaceutical Co., Ltd.

Completed

A Randomized Controlled Study of Postoperative Adjuvant Therapy of Uracil-tegafur (UFT) Compared With Cyclophosphamide/Methotrexate/5-fluorouracil (CMF) in Breast Cancer (NSAS-BC)

Breast Cancer

Japan
Tohoku University

Completed

Vitamin D Supplementation Prevents Elderly Pneumonia

Bacterial Pneumonia

Japan
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

Study of Preoperative Docetaxel or Cisplatin (CDDP) + Docetaxel for C-stage IB-II Non-Small Cell Lung Cancer (NSCLC)

Pulmonary Neoplasms

Japan
Japan Clinical Oncology Group
Ministry of Health, Labour and Welfare, Japan

Completed

A Trial of Doxorubicin/Cyclophosphamide (AC), Docetaxel (D), and Alternating AC and D for Metastatic Breast Cancer

Breast Cancer | Neoplasm Metastasis

Japan
Taiho Pharmaceutical Co., Ltd.

Completed

Comparative Study of Palonosetron With Granisetron as a Control in Patients Receiving Highly Emetogenic Chemotherapy

Chemotherapy-Induced Nausea and Vomiting

Japan
Lu Hua

Not yet recruiting

Effect of Bupivacaine Liposome Anterior Serratus Deep Block on Chronic Pain After Breast Cancer Surgery: a Randomized Controlled Study

Breast Cancer Patients With Chronic Pain After Surgery

China
Cukurova University

Not yet recruiting

Effect of Mobile Application Usage on Drug Compliance After Thyroidectomy

Patient Acceptance of Health Care | Drug Compliance
Oxford Brookes University
University of Oxford

Completed

Physical Exercise for Education ('Fit to Study') (FTS)

Physical Activity | Mental Health Wellness 1 | Cognitive Function 1, Social | Academic Attainment | Fitness Testing

United Kingdom
CONRAD
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Coital Pharmacokinetics/Pharmacodynamics (PK/PD) of Tenofovir Gel

Pharmacokinetics of 1% Tenofovir Gel Following Coitus | Pharmacodynamics of 1% Tenofovir Gel Following Coitus

United States
Ningbo No. 1 Hospital

Recruiting

Conventional Clipping Versus Punching Closure

the Rate of Complete Closure

China
Ningbo No. 1 Hospital

Recruiting

Effectiveness of Mannitol Versus Polyethylene Glycol Electrolyte Dispersion as a Salve for Patients With Inadequate Bowel Preparation: a Randomized Controlled Clinical Trial

Bowel Cleansing; Good Taste

China
Ningbo No. 1 Hospital

Not yet recruiting

Effects of Febuxostat for Lowering Uric Acid in NAFLD Patients With Gout

Nonalcoholic Fatty Liver Disease

China
Ningbo No. 1 Hospital

Completed

Pulsed Field Ablation for Paroxysmal Supraventricular Tachycardia（PSVT）

Paroxysmal Supraventricular Tachycardia

China
Ningbo No. 1 Hospital

Unknown

Prepackaged Nutritional Formulations Versus Restricted Diet for Bowel Preparation

Bowel Preparation

China
Ningbo No. 1 Hospital

Completed

MAFLD-simplified Definition as an Optimized Risk Stratification Tool for Predicting Metabolic Outcomes

Metabolic Associated Fatty Liver Disease
Ningbo No. 1 Hospital

Completed

A Comparison of Bowel Preparation for Colonoscopy Between Digestive Physicians and Non-digestive Physicians

Bowel Preparation

China
University of Yaounde 1

Unknown

The Comparative Efficacy and Safety of Two General Anesthesia Protocols Consisting of Fentanyl Plus Propofol Plus Rococuronium Plus Isoflurane Versus Ketamime Plus Magnesium Sulphate Plus Lidocaine Plus Clonidine Plus Propofol Plus Rococuronium Plus Isoflurane for Gynaecology Surgery in Cameroon (OFA-AFRO)

Surgery | Anesthesia | Clinical Trial | Gynecology | Opioids

Cameroon
Ningbo No. 1 Hospital

Unknown

Reasons for Nonattendance Inpatient Colonoscopy

Inpatient | Colonoscopy Nonattendance

China
University of Oran 1

Completed

Surgical Practices in Algeria : the Cholecystectomy

General Surgery | Cholecystectomy | Practice Guidelines as Topic

Search clinical trials for: Checkpoint kinase 1 CHK1

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