Search clinical trials for: Radium 223

Total 531 results

UCB Pharma SA

Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis (C-early)

Rheumatoid Arthritis

Germany, United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, Czechia, France, Hungary, Ireland, Italy, Mexico, Monaco, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, United Kingdom
UCB Pharma

Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis (C-early)

Rheumatoid Arthritis

Germany, United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, Czechia, France, Hungary, Ireland, Italy, Mexico, Monaco, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, United Kingdom
Global Alliance for TB Drug Development

Completed

Study to Evaluate Safety, Tolerability, and the PK Profile of TBI-223 in Healthy Subjects

Tuberculosis | Tuberculosis, Pulmonary

United States
Global Alliance for TB Drug Development

Completed

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of TBI-223 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary

United States
UCB Pharma SA

Completed

Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures

Epilepsy

Belgium, Finland, France, Germany, Hungary, India, Italy, Netherlands, Poland, Spain, Switzerland, United Kingdom
UCB Pharma

Completed

A Study of the Safety and Effectiveness of Lyophilized Certolizumab Pegol in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Argentina, Australia, Belgium, Bulgaria, Canada, Chile, Croatia, Czechia, Estonia, Finland, France, Hungary, Israel, Latvia, Lithuania, Mexico, New Zealand, Russian Federation, Serbia, Slovakia, Ukraine
UCB Pharma

Completed

Transdermal Rotigotine User Surveillance Study (TRUST)

Idiopathic Parkinson Disease

Czechia, Denmark, Germany, Greece, Italy, Mexico, Romania, Slovakia, Spain, Switzerland
UCB Pharma

Completed

A Comparison of Two Assessment Tools in Predicting Treatment Success of Cimzia in Rheumatoid Arthritis Subjects (PREDICT)

Rheumatoid Arthritis

United States
UCB BIOSCIENCES, Inc.

Completed

Trial to Demonstrate the Efficacy and Safety of Conversion to Lacosamide Monotherapy for Partial-onset Seizures (ALEX-MT)

Epilepsy

Austria, United States, Australia, Canada, Denmark, France, Germany, Ireland, Italy, Poland, Puerto Rico, Spain, United Kingdom
UCB Pharma

Completed

Trial to Assess Long-term Lacosamide (LCM) Monotherapy Use and Safety of LCM Monotherapy and Adjunctive Therapy for Partial-onset Seizures

Epilepsy

United States, Australia, Canada, Denmark, Germany, Italy, Poland, United Kingdom, Spain
UCB BIOSCIENCES GmbH
Aptiv Solutions

Completed

Alprostadil in Peripheral Arterial Occlusive Disease (PAOD) Stage IV (ESPECIAL)

Peripheral Arterial Occlusive Disease

Czechia, Germany, Mexico, Poland, Russian Federation, Ukraine
Instituto Grifols, S.A.

Completed

Safety and Efficacy of Fibrin Sealant Grifols (FS Grifols) During Parenchymous Tissue Open Surgeries

Parenchymous Tissue Surgical Bleeding

United States, Hungary, Russian Federation, Serbia
The Netherlands Cancer Institute
Bayer

Completed

Treatment Outcomes in a Non-study Population of Symptomatic mCRPC Patients Treated With Radium-223 (ROTOR)

Bone Metastases | Prostate Cancer Metastatic

Netherlands
Biruni University

Recruiting

The Effects of Smoking on miRNA-223 Before-After Non-Surgical Periodontal Therapy in Patients With Stage-3, Grade-B Periodontitis

Periodontitis | Periodontal Therapy | Biomarker | miRNA-223

Turkey
Pfizer

Completed

Investigation of the Seropersistence of TBE Antibodies and the Booster Response to FSME-IMMUN 0.5 ml in Adults Aged 18 - 67 Years

Tick-borne Encephalitis

Poland
Medtronic Cardiac Rhythm and Heart Failure
Medtronic

Completed

PREPARE - Primary Prevention Parameters Evaluation

Syncope | Tachycardia, Ventricular | Implantable Cardioverter Defibrillator (ICD) | Fibrillation, Ventricular

United States, Puerto Rico
Kurihama Medical and Addiction Center

Unknown

The Efficacy of Therapy Focused on Desire-satisfaction for Disordered Gamblers (ETFDDG)

Pathological Gambling

Japan
University of Massachusetts, Worcester
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Workplace-Sponsored Diet and Exercise Program to Reduce Obesity

Heart Diseases | Cardiovascular Diseases | Obesity

United States
Azienda Policlinico Umberto I
University of Bologna; Università degli Studi di Sassari; University of Bari... and other collaborators

Unknown

Radical Prostatectomy and External Beam Radiotherapy in mCRPC With 223Radium-dicloride (RaProRad) (RaProRad)

Prostate Cancer

Italy
Rigshospitalet, Denmark

Terminated

Value of FLT PET/CT in Radium-223 Therapy of mCRPC Patients

Metastatic Prostate Carcinoma

Denmark
M.D. Anderson Cancer Center
Bayer; Prostate Cancer Foundation

Completed

Radium 223 in Castrate Resistant Prostate Cancer Bone Metastases

Prostate Cancer

United States
Centro Nacional de Investigaciones Oncologicas...
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina...

Unknown

PRORADIUM: Prospective Multi-centre Study of Prognostic Factors in mCRPC Patients Treated With Radium-223. (PRORADIUM)

Advanced Prostate Cancer | Castration Resistant | Radium 223

Spain
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic, Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer | Prostate Carcinoma Metastatic in the Bone

United States
Radboud University Medical Center
Bayer

Completed

Health-related Quality of Life, Psychological Distress and Fatigue in Metastatic CRPC Patients Treated With Radium-223

Bone Metastases | Castrate Resistant Prostate Cancer

Netherlands
University of Washington
Bayer

Recruiting

Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8

United States
University Health Network, Toronto
Bayer

Active, not recruiting

Radium-223 Combined With Dexamethasone as First-line Therapy in Patients With M+CRPC (TRANCE)

Metastatic Prostate Cancer

Canada
Cancer Trials Ireland

Completed

Radium-223 in Combination With Enzalutamide

Prostate Cancer

Ireland
Bayer

Completed

A Local Retrospective Observational Study to Evaluate the Treatment Patterns of mCRPC Patients in Belgium Treated With Radium-223 (BELFIGO)

Prostatic Neoplasms, Castration-Resistant

Belgium
Bayer

No longer available

Radium-223 Dichloride (BAY88-8223) in Castration-Resistant (Hormone-Refractory) Prostate Cancer Patients With Bone Metastases

Prostatic Neoplasms

United States
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Efficacy of Radium 223 in Radioactive Iodine Refractory Bone Metastases From Differentiated Thyroid Cancer (RAD-THYR)

Thyroid Cancer

France
Bayer

Completed

A Study to Learn More About How Radium-223 Affects the Quality of Life of Colombian Patients With Prostate Cancer That Has Not Responded to Testosterone Lowering Treatment and Has Spread to the Bones, and to Better Understand Its Safety (QOLRAD)

Prostate Cancer

Colombia
Bayer

Completed

Study to Gather Information About the Use of Healthcare Services and the Way the Disease is Cared for in Canadian Patients With Prostate Gland Cancer Which Spread Throughout the Body (REACTIVATE)

Prostate Cancer

Canada
Bayer

Completed

EPIX, a Study to Gather More Information About Characteristics of Patients and Other Factors Which May Contribute to Survival Over a Long Period of Time in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) Treated With Radium-223 (Xofigo) (EPIX)

Metastatic Castration Resistant Prostate Cancer (mCRPC)

United States
Angela Taber MD
Bayer; The Miriam Hospital; Rhode Island Hospital

Completed

BrUOG L301 With Non-Small Cell Lung Cancer and Bone Metastases

Non Small Cell Lung Cancer With Bone Metastatses

United States
Bayer

Completed

Radium-223 Dichloride Asian Population Study in the Treatment of CRPC Patients With Bone Metastasis

Prostatic Neoplasms

China, Singapore, Taiwan, Korea, Republic of
Bayer

Completed

A Drug Utilization Study of Radium-223 in Sweden

Neoplasms

Sweden
Bayer

Completed

BAY88-8223, Does Response Study in HRPC Patients

Bone Metastases | Hormone Refractory Prostate Cancer
GenesisCare USA
Bayer

Withdrawn

Darolutamide With Radium-223 or Placebo and the Effect on Radiological Progression-Free Survival for Patients With mCSPC (CARE)

Metastatic Prostate Cancer
Bayer

Completed

Dose Escalation Study of Radium-223 Dichloride in Patients With Advanced Skeletal Metastases

Neoplasm Metastasis

Sweden, Norway
Bayer

Active, not recruiting

Drug Use Investigation of Xofigo, Castration Resistant Prostate Cancer With Bone Metastases

Prostatic Neoplasms, Castration-Resistant

Japan
Bayer

Completed

Non-interventional Study With Ra-223 Dichloride Assessing Overall Survival and Effectiveness Predictors for mCRPC Patients in a Real Life Setting in Germany (URANIS)

Prostatic Neoplasms, Castration-Resistant

Germany
Bayer

Completed

Alpharadin™ (Radium-223 Chloride) Safety and Dosimetry With HRPC That Has Metastasized to the Skeleton

Prostate Cancer | Pharmacokinetics | Metastases

United States
Bayer

Completed

A Placebo-controlled Phase II Study of Bone-targeted Radium-223 in Symptomatic Hormone-refractory Prostate Cancer

Neoplasm Metastasis | Prostate Cancer

Sweden, United Kingdom
Sir Mortimer B. Davis - Jewish General Hospital

Completed

Metabolic Change in Prostate Cancer Bone Metastases on 68Ga-HBED-CC-PSMA PET/CT Following Radium-223 Therapy

Prostate Cancer

Canada
The Netherlands Cancer Institute
Bayer

Completed

Registry of Treatment Outcomes of Symptomatic Metastasized Castration Resistant Prostate Cancer Treated With Radium-223 (ROTOR)

Bone Metastases | Prostate Cancer Metastatic

Netherlands
Bayer

Completed

Re-treatment Safety of Radium-223 Dichloride in Castration-resistant Prostate Cancer With Bone Metastases

Prostatic Neoplasms

United States, Israel, Spain, Italy, Sweden, Norway, Finland
Bayer

Completed

BAY88-8223, Dose Finding Study in Patients With HRPC

Neoplasm Metastasis | Prostate Cancer

United Kingdom
Bayer

Terminated

A Research Called CREDIT Studies How Safe the Study Treatment Radium-223 is and How Well it Works in Chinese Men With Advanced Prostate Cancer That Has Spread to the Bones and Does Not Respond to Treatments for Lowering Testosterone Levels (CREDIT)

Bone Metastases | Metastatic Castration-resistant Prostate Cancer

China
Bayer

Completed

Radium(223) Dichloride (Alpharadin) in Castration-Resistant (Hormone-Refractory) Prostate Cancer Patients With Bone Metastases

Prostatic Neoplasms

Belgium, Spain, Canada, France, Switzerland, Germany, United Kingdom, Denmark, Russian Federation, Sweden, Israel, Italy, Netherlands, Norway, Czech Republic, Finland, Poland, Ireland, Mexico
Bayer

Completed

Safety, Biodistribution, Radiation Dosimetry and Pharmacokinetics Study of BAY88-8223 in Japanese Patients

Prostatic Neoplasms

Japan

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