Search clinical trials for: protein adduct

Total 22545 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Durvalumab and Tremelimumab Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Stage II-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC... and other conditions

United States
Denver Health and Hospital Authority
University of Colorado, Denver; Johnson & Johnson Consumer Inc., McNeil Consumer... and other collaborators

Withdrawn

APAP-CYS Protein Adduct Concentrations in Patients With Liver-Directed Therapy Intended to Treat Hepatic Tumors

Acetaminophen Exposure

United States
University of Edinburgh
Rajarata University, Sri Lanka

Completed

An Investigation Into the Cardiovascular Risk and Aetiology of CKDu in Sri Lanka

Proteinuria | Arterial Stiffness | CKDu | Serum Creatinine | Urinary Biomarkers | DNA Adducts

Sri Lanka
Denver Health and Hospital Authority
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Aminotransferase Trends During Prolonged Acetaminophen Dosing

Healthy | Drug Toxicity

United States
Denver Health and Hospital Authority
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Acetaminophen-Protein Adduct Resolution (AR)

Acetaminophen-protein Adduct Formation

United States
Kennon Heard
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Acetaminophen Adduct Formation in Non-Drinkers Taking Therapeutic Doses of Acetaminophen for Ten Consecutive Days (Non-Drinker)

Drug Induced Liver Injury

United States
Sun Yat-sen University

Not yet recruiting

HAIC Combined With Adebrelimab Plus Apatinib as the First-line Treatment for HCC in BCLC Stage C: An Open-label, Single-arm, Phase II Study

Hepatocellular Carcinoma
University Hospital, Grenoble

Not yet recruiting

Validation of an Alzheimer's Disease Marker by Fecal Assay of Amyloid Peptides and Tau Proteins (FecAlz)

Alzheimer Disease
West China Hospital

Recruiting

Efficacy of Organoid-Based Drug Screening to Guide Treatment for Locally Advanced Thyroid Cancer

Locally Advanced Thyroid Gland Carcinoma

China
University Medical Center Groningen

Not yet recruiting

Bleeding in Multiple Myeloma (BiMM)

Multiple Myeloma
Christian Schmidt, MD
Johannes Gutenberg University Mainz

Recruiting

CAR-T-cell Treatment for Untreated High Risk MANtle Cell Lymphoma (CARMAN)

Mantle Cell Lymphoma

Germany
Yunpeng Liu
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Adebrelimab Plus Apatinib for Maintenance Therapy of Extensive Small Cell Lung Cancer

Small Cell Lung Cancer

China
University Health Network, Toronto
Ontario Shores Centre for Mental Health Sciences

Recruiting

i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial (Ket-CBT)

Suicide | Major Depressive Disorder | Treatment Resistant Depression

Canada
Pfizer

Not yet recruiting

Non Interventional Study to Investigate the Safety and Effectiveness in Patients With Relapsed and Refractory Multiple Myeloma Treated With Elranatamab Under the Actual Use.

Relapsed and Refractory Multiple Myeloma (RRMM)
Charite University, Berlin, Germany

Recruiting

Influence of Protein Intake on Muscle Mass and Health-related Quality of Life During and After Radiotherapy (pROtein)

Malnutrition; Cachexia

Germany
Hunan Province Tumor Hospital

Not yet recruiting

The Recurrence Gene Profiles of Adjuvant Osimertinib Therapy in Resected Non-Small-Cell Lung Cancer (RAISE)

Non-small Cell Lung Cancer
Henan Cancer Hospital

Recruiting

Backline Treatment of Advanced Hepatocellular Carcinoma With Palbociclib

Hepatocellular Carcinoma

China
Assiut University

Recruiting

The Effect of Active Nutritional Support On Quality Of Life In Patients With Head And Neck Cancer Receiving Radiotherapy

Head and Neck Neoplasms

Egypt
Universitaire Ziekenhuizen KU Leuven
Janssen Pharmaceutica

Not yet recruiting

Study on the Clinical Efficacy of Teclistamab (TECTONIC)

Hematologic Diseases | Multiple Myeloma

Belgium
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Not yet recruiting

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Refractory Differentiated Thyroid Gland Carcinoma
Bristol-Myers Squibb

Not yet recruiting

A Study Evaluating Deucravacitinib Concentrations in the Breast Milk and Plasma of Healthy Lactating Female Participants

Healthy Volunteers
Tang-Du Hospital
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Recruiting

Adebrelimab + Apatinib in SCLC Maintenance Therapy

SCLC

China
RenJi Hospital

Not yet recruiting

Efficacy and Safety of Rivaroxaban in the Early Postoperative Period for Patients With Bioprosthetic Valves

Anticoagulation
M.D. Anderson Cancer Center

Not yet recruiting

A Phase I Study Investigating the Combination of Cladribine, Low Dose Cytarabine and Sorafenib Alternating With Decitabine in Pediatric Relapsed and Refractory Acute Leukemias

Refractory Acute Leukemia | Relapsed Acute Leukemia

United States
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients (CLAD)

Lung Transplant

United States, Canada
Chang Gung Memorial Hospital

Recruiting

Study To Evaluate The Efficacy Of Tofacitinib In Patients With SJS/TEN

Stevens-Johnson Syndrome | Toxic Epidermal Necrolysis

Taiwan
AC Camargo Cancer Center

Recruiting

Everolimus 5 mg vs 10 mg/Daily for Patients With Neuroendocrine Tumors (EVENET)

Progression | Neuroendocrine Tumors | Neuroendocrine Tumor of the Lung | Neuroendocrine Tumor Grade 2 | Neuroendocrine Tumor Grade 1 | Neuroendocrine Tumor of Pancreas | Neuroendocrine Tumor Carcinoid

Brazil
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Zanubrutinib and G-CHOP in Untreated Intermediate-high Risk Follicular Lymphoma

FL
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Effects of Transcranial Direct Current Stimulation (tDCS) on Inhibition and Brain Function in Primary Progressive Aphasia (Stim-APHA)

Aphasia, Primary Progressive
The First Affiliated Hospital with Nanjing Medical...
Nanjing Legend Biotech Co.

Not yet recruiting

LCAR-M61S and LCAR-M61D in Treatment of Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

China
Centre Hospitalier Universitaire de Saint Etienne

Not yet recruiting

Comparison of the Effects of Apixaban on Thrombin Generation in Patients With de Novo Multiple Myeloma (ProApix)

Multiple Myeloma | Total Knee Replacement

France
Janssen-Cilag Ltd.

Recruiting

A Real-world Study in Participants With Smoldering Multiple Myeloma

Smoldering Multiple Myeloma

France
University of Oregon
McMaster University

Recruiting

Family Caregiver Online Survey (Dementia and Swallowing Difficulties)

Dementia | Dysphagia | Dementia, Vascular | Dementia, Mixed | Dementia With Lewy Bodies | Dementia Alzheimers | Dementia, Mild | Parkinson Disease Dementia | Dementia Moderate | Dementia Severe | Dementia Frontal | Dementia Frontotemporal

United States
Chinese PLA General Hospital

Recruiting

A Phase ll Trial of the Combination of Zanubrutinib, Rituximab and Venetoclax in Patients With Previously Untreated Follicular Lymphoma (ZARAV)

Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage III Follicular Lymphoma | Ann Arbor Stage IV Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma

China
Zhiyong Huang
Hubei Cancer Hospital; Wuhan Union Hospital, China; Renmin Hospital of Wuhan... and other collaborators

Recruiting

Palliative Hepatectomy Combined With Targeted Therapy and Immunotherapy for Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

China
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

United States
University of North Carolina, Chapel Hill

Not yet recruiting

Comparing Train-of-Four Recovery in the Adductor Pollicis Versus the Adductor Digiti Minimi in Elective Surgery Patients

Anesthesia | Neuromuscular Blockade

United States
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Efficacy and Safety of Dupilumab in Combination With Tofacitinib in Moderate to Severe Adult AD Patients

Atopic Dermatitis
Kerry Rogers

Not yet recruiting

Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
ETH Zurich

Recruiting

Pilot Trial: Bioavailability Animal vs. Plant Protein Drink

Nutrition, Healthy | Leucine Sensitivity

Switzerland
First Affiliated Hospital of Zhejiang University
First Affiliated Hospital of Wenzhou Medical University; The Affiliated Hospital... and other collaborators

Recruiting

Primary Multiple Myeloma Who Achieved MRD Negativity After Induction Therapy, ASCT or Not

Multiple Myeloma | Minimal Residual Disease

China
Nanjing IASO Biotechnology Co., Ltd.

Recruiting

A Phase III Study of Eque-cel in Subjects With Len-refractory RRMM (FUMANBA-03) (FUMANBA-03)

Multiple Myeloma

China
The First Affiliated Hospital of Henan University...

Not yet recruiting

Adebrelimab in Combination With Apatinib and Chemotherapy/Chemoradiotherapy in Immuno-experienced Second-line ESCC.

Esophageal Cancer

China
Yunpeng Liu
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Irinotecan Hydrochloride Liposome Combined With Capecitabine and Lenvatinib in Patients With Biliary Tract Carcinoma

Biliary Tract Carcinoma

China
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Sonrotoclax, Zanubrutinib and CD20mab in Untreated MCL Patients

MCL
University of Central Florida

Not yet recruiting

Collagen Protein Versus Placebo on Muscle Recovery

Anthropometrics: Height and Weight | Isometric Standing and Seated Plantarflexion | Calf Muscle Thickness | Achilles Tendon Length and Thickness | Myotonography of the Calf Musculature and Achilles Tendon | Pain Pressure Threshold of the Calf | Pain Scale | Endurance Calf Test | Dietary Analysis

United States
National Cancer Institute (NCI)

Not yet recruiting

Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Hard-to-Treat Multiple Myeloma

Multiple Myeloma
AbbVie

Not yet recruiting

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis (Start Up)

Atopic Dermatitis
University of Melbourne
Monash University; University of Adelaide; University of Sydney; The University... and other collaborators

Not yet recruiting

PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol] (PLATIPUS)

Preterm Birth
Uniformed Services University of the Health Sciences
Henry M. Jackson Foundation for the Advancement of Military Medicine

Recruiting

The Effect of Omega-3 Fortified Smoothies on Omega-3 Index and Physical Performance Related Outcomes Among Soldiers (H2FO3)

Nutrition, Healthy

United States

Search clinical trials for: protein adduct

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