Search clinical trials for: Tocilizumab (TCZ)

Total 1605 results

SK Life Science, Inc.

Completed

Bioavailability and Food Effect Study of Cenobamate as an Oral Suspension and Tablet

Healthy

United States
Xiaoshun He
Lion TCR Pte. Ltd.

Unknown

TCR-Redirected T Cell Treatment in Patients With Recurrent HBV-related Hepatocellular Carcinoma Post Liver Transplantation

Recurrent Hepatocellular Carcinoma

China
Massachusetts General Hospital
Deborah Munroe Noonan Memorial Research Fund

Completed

Feasibility and Effectiveness of Computerized Cognitive Training in Adolescents With Autism Spectrum Disorder (MGHTCT)

Autism Spectrum Disorder
Biomimedica, Inc

Terminated

A Prospective, Multicenter, Single Arm Feasibility Study of the Safety and Performance of GRADION™ Hip Total Cartilage Replacement (TCR)™ in the Treatment of Degenerative Joint Disease of the Hip

Degenerative Joint Disease of the Hip

Netherlands
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Transmural Systems Transcaval Closure Device for Transcaval Access Ports During Transcatheter Aortic Valve Replacement

Aortic Stenosis

United States
Singapore General Hospital
Duke-NUS Graduate Medical School; Singapore College of Traditional Chinese...

Unknown

Traditional Chinese Medicine for Treatment of Irritable Bowel Syndrome

Irritable Bowel Syndrome

Singapore
Dushu Lake Hospital Affiliated to Soochow University

Recruiting

Natural Killer (NK) Cells (XS005) Injection Combined With Stupp Regimen for Adjuvant Chemotherapy in Subjects With Primary Glioblastoma(GBM)

Glioblastoma | GBM

China
Boehringer Ingelheim

Completed

BIBW 2992 (Afatinib) With or Without Daily Temozolomide in the Treatment of Patients With Recurrent Malignant Glioma

Glioma

United States, Canada
Hoffmann-La Roche

Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma

United States, Israel, Italy, Spain, United Kingdom
Abramson Cancer Center at Penn Medicine
Genentech, Inc.

Recruiting

Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy

Lung Cancer, Nonsmall Cell

United States
Thomas Wekerle
University Hospital Regensburg

Active, not recruiting

Cell Therapy for Immunomodulation in Kidney Transplantation

Kidney Transplantation

Austria
Hoffmann-La Roche

Active, not recruiting

Trial of Mosunetuzumab (BTCT4465A) as Consolidation Therapy in Participants With Diffuse Large B-Cell Lymphoma Following First-Line Immunochemotherapy and as Monotherapy or in Combination With Polatuzumab Vedotin in Elderly/Unfit Participants With Previously Untreated Diffuse Large B-Cell Lymphoma

Diffuse Large B-cell Lymphoma

United States, Israel, Spain, Korea, Republic of, Poland, Taiwan
Hoffmann-La Roche

Completed

An Open-Label, Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab in Combination With Tiragolumab With or Without Atezolizumab in Participants With B-Cell Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Follicular Lymphoma

United Kingdom, Belgium, United States, Australia, Canada, Germany
Hoffmann-La Roche

Completed

A Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive Melanomas

Uveal Melanoma | Cutaneous Melanoma | Mucosal Melanoma

Spain, United States, Belgium, Denmark, Canada, Australia
M Abdur Rahim Medical College and Hospital
First Affiliated Hospital Xi'an Jiaotong University; Cox's Bazar 250 Bed District... and other collaborators

Completed

Efficacy and Safety of Remdesivir and Tociluzumab for the Management of Severe COVID-19: A Randomized Controlled Trial

Covid19 | Covid-19 ARDS

Bangladesh
Taipei Veterans General Hospital, Taiwan

Recruiting

To Evaluate the Short-term and Long Term Efficacy of Acupuncture in Ocular and Oral Dryness Symptoms of Dry Eye Syndrome

Dry Eye Syndrome | Xerophthalmia

Taiwan
Shanghai University of Traditional Chinese Medicine
Fudan University; Shanghai Zhongshan Hospital; Ruijin Hospital; Shanghai Chest... and other collaborators

Not yet recruiting

Clinical Study on the Prevention of Driver Gene Negative II-IIIa Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors

Lung Cancer

China
University Hospital, Essen

Completed

Efficacy and Safety of TCA vs. ECA for the Treatment of AIN in HIV-positive Patients (TECAIN)

Anal Intraepithelial Neoplasia (AIN) in HIV-infected Patients

Germany
University of Pennsylvania
Adaptimmune

Completed

Redirected High Affinity Gag-Specific Autologous T Cells for HIV Gene Therapy

HIV Infections

United States
University of Michigan

Completed

Platelet Derived Growth Factor Stimulates Bone Fill and Rate of Attachment Level Gain

Periodontitis

United States
F. Stephen Hodi, MD
MedImmune LLC

Completed

Phase I Clinical Trial of Tremelimumab Plus MEDI3617 in Patients With Unresectable Stage III or Stage IV Melanoma

Metastatic Melanoma

United States
University Hospital for Infectious Diseases, Croatia

Unknown

Serum IL-6 and Soluble IL-6 Receptor in Severe COVID-19 Pneumonia Treated With Tocilizumab (UHID-COVID19)

COVID-19 | Severe Pneumonia

Croatia
UCB Pharma

Completed

Efficacy and Safety of CDP6038 in Patients With Rheumatoid Arthritis With an Unsuccessful Response to Anti-Tumor Necrosis Factor (Anti-TNF) Therapy

Rheumatoid Arthritis

United States, Belgium, United Kingdom
The Second Hospital of Hebei Medical University

Recruiting

Safety and Efficacy of TRPP Therapy in Glioblastoma Multiforme

Glioblastoma Multiforme

China
University of Sao Paulo
Brain4Care USA Corp.

Recruiting

A Novel Non-invasive Technique of Cerebral Compliance and Auto-regulation Assessment

Intracranial Hypertension

Brazil
Victor Aquino

Temporarily not available

Treatment Use of the CliniMACS® CD34 TCR Alpha/Beta for Allogenic Transplant (Expanded Access Use)

Transplant-Related Disorder | GVH - Graft Versus Host Reaction

United States
T-knife GmbH

Terminated

A Phase 1/ 2, First-in-Human, Open-Label, Accelerated-Titration, Two-Part Clinical Trial of TK-8001 in Patients With HLA-A*02:01 Genotype and Advanced-Stage/ Metastatic MAGE-A1+ Solid Tumors (IMAG1NE)

Advanced Solid Tumors

Germany, Belgium, Spain, Netherlands, United Kingdom
National and Kapodistrian University of Athens

Completed

Pulsatility Index, Vasomotor Reactivity and Leukoencephalopathy in Fabry Patients

Fabry Disease

Greece
Centro Hospitalar De São João, E.P.E.
University of Padova; Clinical Hospital Centre Zagreb; University of Giessen; University...

Completed

Microembolic Detection in Acute Ischemic Stroke Patients With Atrial Fibrillation and Outcome

Embolism | Atrial Fibrillation | Infarction, Brain

Portugal
Second Affiliated Hospital, School of Medicine,...

Unknown

Clinical Efficacy of Combination Therapy Based on High-dose Biapenem in CRKP Infections

High-dose Biapenem

China
Massachusetts General Hospital
National Cancer Institute (NCI)

Completed

Bevacizumab w / Temozolomide PET & Vascular MRI For GBM

Recurrent Glioblastoma

United States
Escuela Neijing

Completed

Efficacy of Acupuncture in Macular Diseases (AMAD)

Age-related Macular Degeneration | Stargardt Disease | Macular Dystrophy

Colombia
The Hong Kong Polytechnic University

Unknown

Traditional Chinese Medicine Pediatric Massage for Attention Deficit Hyperactivity Disorder Symptoms

ADHD
Hoffmann-La Roche

Recruiting

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

Belgium, Australia, Denmark, Spain, Taiwan, France, Italy, United States, Canada, Czechia, New Zealand, Poland, Finland
Hoffmann-La Roche

Completed

An Observational Study of RoActemra/Actemra (Tocilizumab) As Monotherapy in Rheumatoid Arthritis Patients in Routine Clinical Practice (ACT SOLO)

Rheumatoid Arthritis

France
Universitätsklinikum Hamburg-Eppendorf

Not yet recruiting

NIRS vs TCD for Cerebrovascular Autoregulation During Non-cardiac Surgery (SONICA)

Cerebrovascular Circulation

Germany
Guangzhou 8th People's Hospital
Sun Yat-sen University

Completed

Effect of Chidamide Combined With CAT-T or TCR-T Cell Therapy on HIV-1 Latent Reservoir

HIV/AIDS

China
University of Colorado, Denver
Children's Hospital Colorado; Bright by 3; Daniels Fund; Piton Foundation; Gantz...

Terminated

Bright by Three (BB3) Effectiveness Study

Developmental Delay

United States
Virchow Group

Completed

Efficacy and Safety of PERIOGEN in the Treatment of Periodontal Bone Defect

Intrabony Periodontal Defect

India
Sun Yat-sen University
Guangdong Xiangxue Precision Medical Technology Co., Ltd.

Recruiting

Phase II Study of TAEST16001 in Soft Tissue Sarcoma

Soft Tissue Sarcoma

China
Inonu University

Completed

The Effect of Aromatherapy With Thyme Oil on Disease Symptoms, Vital Signs, Hemodynamic Parameters in COVID-19 Patients

Patient Engagement

Turkey
Dr Sze-Yuan Ooi
The University of New South Wales; The George Institute; South Eastern Sydney...

Unknown

Evaluation of a Remote Monitoring Smartphone Application and Care Model of COVID-19 Patients in the Community (ReCOVER) (ReCOVER)

COVID

Australia
Chang Gung Memorial Hospital

Unknown

The Analysis of Chinese Medical Syndromes Differentiation on Acute Ischemic Stroke

Ischemic Stroke
Theraclone Sciences, Inc.

Completed

Safety Study of Anti-Influenza Virus Monoclonal Antibody to Treat Influenza

Influenza, Human

United States
The First Affiliated Hospital of Anhui University...
China Academy of Chinese Medical Sciences; Beijing University of Chinese Medicine

Completed

A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of Hand, Foot, and Mouth Disease

Hand, Foot and Mouth Disease

China
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate Safety and Pharmacokinetics of VX-659 in Healthy Subjects and in Adults With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Peking Union Medical College Hospital
Beijing Tiantan Hospital; Tianjin Medical University General Hospital

Unknown

Efficacy and Safety of TMZ Plus CDDP in the Patients With Recurrent Malignant Gliomas

Malignant Gliomas

China
Hoffmann-La Roche

Completed

A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Brazil, United Kingdom, Canada, Argentina, Mexico, Austria, Israel, Colombia, Peru, Russian Federation, Philippines, Puerto Rico, Germany, Greece, Poland, Spain, France, Singapore, China, South Africa, Hungary, Denmark, Finlan... and more
Center Trials & Treatment Europe

Completed

Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma

Gliosarcoma | Glioma, Malignant | Astrocytoma of Brain

Georgia, Bosnia and Herzegovina, Bulgaria
Hoffmann-La Roche

Completed

A Phase Ib Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Cibisatamab in Combination With Atezolizumab After Pretreatment With Obinutuzumab in Participants With Previously Treated Metastatic Colorectal Adenocarcinoma

Colorectal Cancer

United States, France, Denmark, Spain

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