Search clinical trials for: Open apex

Total 8940 results

University of Derby
University of Exeter; University Hospitals of Derby and Burton NHS Foundation... and other collaborators

Not yet recruiting

An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID. (ERASE-LC)

COVID-19 | SARS-CoV-2 Infection

United Kingdom
National Institute of Allergy and Infectious Diseases...

Recruiting

Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults

Malaria

United States
Semmelweis University

Recruiting

Application of Surgical Templates in the Surgical Exposure of Impacted Canines

Impacted Tooth

Hungary
Servier Affaires Médicales

Recruiting

An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy.

Acute Myeloid Leukemia (AML)

Netherlands, Italy, Austria, France
McMaster University
Western University

Not yet recruiting

ciNPT in Autologous DIEP Flap Breast Reconstruction

Breast Cancer | Wound Dehiscence, Surgical
University of Texas at Austin

Recruiting

Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline

Mild Cognitive Impairment

United States
3M

Recruiting

Evaluating the Efficacy and Safety of the VERAFLO™ Dressing Kit for Wound Bed Preparation in Open Wounds

Wound Healing

China
University of Southern Denmark

Recruiting

Open Versus Robotic-assisted Ventral Hernia Repair, Short and Long-term Outcome

Abdominal Hernia

Denmark
National Taiwan University Hospital

Not yet recruiting

Efficacy of Lenalidomide Maintenance in Primary Central Nervous System Lymphoma and Primary Vitreoretinal Lymphoma: a Phase II, Open-label, Single-arm Study

Primary Central Nervous System Lymphoma and Primary Vitreoretinal Lymphoma
Novartis Pharmaceuticals

Recruiting

An Open Label Extension (OLE) Study to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) (OLE)

Hyperlipoproteinemia (a)

Germany
Erasmus Medical Center

Recruiting

TEIPP Immunotherapy in Patients With NSCLC (TEIPP)

Non Small Cell Lung Cancer

Netherlands
National Taiwan University Hospital

Not yet recruiting

Regulation of Intraocular Pressure in Glaucoma Patients by Acupressure

Primary Open Angle Glaucoma | Acupressure
University of Malaya

Recruiting

Analgesic Effect of IntraPeritoneal LIGNOcaine in Gynaecological Open Surgery

Postoperative Pain | Gynecologic Disease | Local Anesthetic Systemic Toxicity

Malaysia
Medical University of South Carolina
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes...

Recruiting

rTMS in Older Adults With MCI and AUD

Transcranial Magnetic Stimulation | Mild Cognitive Impairment | Alcohol Use Disorder

United States
Inhibrx, Inc.

Not yet recruiting

Open Label Extension Study of INBRX-101 in Adults With AATD Emphysema (ELEVAATE OLE)

Emphysema | Alpha 1-Antitrypsin Deficiency
Shionogi

Recruiting

Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection (SCORPIO-PEP)

SARS-CoV-2 Infection

Japan, United States
Peking University People's Hospital

Not yet recruiting

Study and Transformation of Tumor Molecular Features Screening Model of Endometrial Carcinoma Surgical Approach

Endometrial Carcinoma | Tumor Molecular Features Screening Model
Centre Francois Baclesse
National Cancer Institute, France

Not yet recruiting

Long-term Cognitive and Functional Impact of Proton-therapy or Modern Fractionated Radiotherapy in Cavernous Sinus Meningioma: An Open-label Randomized 1:1 Phase III Study (COG-PROTON-01)

Cognitive Impairment | Cavernous Sinus Meningioma | Proton-therapy | Photon Radiotherapy

France
Advanced Integrative Medical Science Institute

Not yet recruiting

Open-Label Dose-Ranging Study of Oral SM-001 in Healthy Adults

Major Depression | Post Traumatic Stress Disorder

United States
Yonsei University

Not yet recruiting

An Open Label, Single-arm, Multicenter Phase Ib/II Study to Evaluate the Safety and Efficacy of T-Dxd in Combination With Ramucirumab as a 2nd Line in Patients With HER2 Low Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Gastric Cancer | Gastroesophageal Junction (GEJ) Cancer
Mingche Biotechnology CO., LTD

Not yet recruiting

Evaluate the Efficacy and Safety of Glaucoma Implant in Primary Open Angle Glaucoma

Glaucoma
mohamed A Aboelsuod, MD

Recruiting

Ultrasound Guided Erector Spinae Block Versus Thoracic Para-vertebral Block Versus Quadratus Lamborum Block in Open Renal Surgeries

Renal Disease

Egypt
Shanghai Pulmonary Hospital, Shanghai, China

Not yet recruiting

Neoadjuvant Therapy With Toripalimab and JS004 Combined With Platinum-based Doublet Chemotherapy for Resectable or Potentially Resectable Stage III Non-small Cell Lung Cancer: A Randomised Controlled, Open-label, Phase 2 Trial

Stage III Non-small Cell Lung Cancer
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy (Step-Up HS)

Hidradenitis Suppurativa

United States, Japan, Australia, Canada, Korea, Republic of, New Zealand, Puerto Rico, Spain, Austria, Italy, Bulgaria, Israel, Taiwan, Croatia, Hungary, Netherlands, Switzerland, Germany, Portugal, France, United Kingdom, Czechia, ... and more
NorthSea Therapeutics B.V.

Recruiting

Study of the Efficacy and Safety of NST-1024 Versus Placebo in Subjects With Hypertriglyceridemia

High Triglycerides

United States
Fudan University

Not yet recruiting

A Randomized, Controlled, Open-label Clinical Trial of Adjuvant Intensive Therapy for HR+/ HER2-SNF4 Early Breast Cancer

HR+/HER2-breast Cancer
CHU de Quebec-Universite Laval
Canadian Institutes of Health Research (CIHR); Quebec Breast Cancer Foundation

Recruiting

Pilot Study of PACHA Program to Enhance Adherence to Adjuvant Endocrine Therapy Among Breast Cancer Survivors (PACHA)

Breast Cancer | Breast Neoplasms

Canada
Centre Hospitalier Universitaire de Saint Etienne
Ministry of Health, France

Not yet recruiting

Hysterectomy by Transvaginal Natural Orifice Transluminal Endoscopic Surgery Versus or Laparoscopic Hysterectomy (vNOTESHC)

Hysteromyoma

France
Merz Therapeutics GmbH
Heinrich-Heine University, Duesseldorf

Recruiting

Assessment of Long-term Clinical Response to BoNT in Cervical Dystonia (RELY-CD)

Cervical Dystonia

Germany
Myra Vision Inc.

Recruiting

Feasibility Clinical Evaluation of the Calibreye System

Glaucoma, Open-Angle

Panama, India, Mexico
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

An Open-label Phase 3 Study of Lutetium (177Lu) Oxodotreotide Injection in Subjects With Advanced Gastrointestinal Pancreatic Neuroendocrine Tumors.

Advanced Gastroenteropancreatic Neuroendocrine Tumor

China
Amgen

Recruiting

A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-ASCEND)

Atopic Dermatitis

United States, Japan, Korea, Republic of, Australia, Taiwan, Spain, Switzerland, Germany, Croatia, Austria, Bulgaria, France, Denmark, China, Netherlands, Hungary, Czechia, Poland, Brazil, Greece, Portugal, Italy, Finland, Argentina, Sl... and more
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC; InSightec

Not yet recruiting

Randomized Study of Neo-adjuvant and Adjuvant Pembrolizumab With and Without Targeted Blood Brain Barrier Opening Using Exablate MRI-guided Focused Ultrasound (Exablate MRgFUS) for Recurrent Glioblastoma

Recurrent Glioblastoma

United States
River 2 Renal Corp.

Recruiting

Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome

Acute Kidney Injury | Hepatorenal Syndrome

United States
Memorial Sloan Kettering Cancer Center
Sanofi

Recruiting

Open-Label, Phase II Trial of Isatuximab for Patients With Refractory Immune Cytopenias After Allogeneic Hematopoietic Cell Transplantation

Blood Cancer | Refractory Immune Cytopenias

United States
Sohag University

Not yet recruiting

Electroretinogram and Retinal Vascular Changes After Cataract Surgery

Primary Open Angle Glaucoma
Tianjin Medical University Cancer Institute and...

Recruiting

A Multicenter, Randomized, Open, Phase III Trial of ddEC-THPvs Evaluating the Efficacy and Safety of TCHP Neoadjuvant Therapy for HER2-positive Breast Cancer

HER-2 Positive Breast Cancer

China
Akeso

Recruiting

A Phase Ia/Ib Open Label，Clinical Study Evaluating the Safety, Tolerability and Preliminary Efficacy of AK127 in Combination With AK104 in Patients With Advanced Malignant Tumors

Advanced Malignant Tumors

China
Mersin University

Recruiting

Psychosocial Nursing Interventions on Sleep, Anxiety and Delirium in Patients Undergoing Open Heart Surgery

Delirium

Turkey
Kuopio University Hospital
Helsinki University Central Hospital; Päijänne Tavastia Central Hospital; Jyväskylä... and other collaborators

Not yet recruiting

Open and Endoscopic Technique in Female Inguinal Hernia Repair. FemaleHernia

Post Operative Pain

Finland
Ichnos Sciences SA

Recruiting

Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

United States, Australia
National Allergy Research Center, Denmark

Not yet recruiting

Repeated Open Application Test (ROAT) Study With Hydroperoxides of Linalool

Allergic Contact Dermatitis
Laboratorios Poen

Recruiting

Dorzolamide+Timolol Multidose Preservative-free vs Dorzolamida+Timolol BAK Preserved Efficacy and Safety

Ocular Hypertension | Glaucoma, Open-Angle

Argentina
Shantou University Medical College
Guangdong ProCapZoom Biosciences Co., Ltd.

Not yet recruiting

Single-arm, Open-label Clinical Study of SZ011 in the Treatment of Ovarian Epithelial Carcinoma

Ovarian Epithelial Carcinoma
University of Novi Sad

Recruiting

Dexmedetomidinine in the Prevention of Postoperative Delirium in the Intensive Care Unit After Cardiac Surgery

Intensive Care Unit Delirium

Serbia
Sinovac Biotech Co., Ltd

Recruiting

A Multi-center, Open-labelled, Randomized, Controlled, Extended Phase Ⅲ Clinical Trial of sIPV Vaccine

Poliomyelitis | Polio

Pakistan, Bangladesh
PRG Science & Technology Co., Ltd.

Not yet recruiting

Phase 2, Open-Label Study to Evaluate the Safety and Tolerability of Progerinin in Werner Syndrome

Werner Syndrome
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Recruiting

A Phase 1, Open-Label Study to Evaluate the Effect of a Low-Fat Meal and Multiple Doses of Ciprofloxacin on the Pharmacokinetics of Vorasidenib in Healthy Subjects

Healthy Subjects

United States
Shantou University Medical College
Guangdong ProCapZoom Biosciences Co., Ltd.

Not yet recruiting

Single-arm, Open-label Clinical Study of SZ003 in the Treatment of Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma
59th Medical Wing
Nanodropper, Inc.

Recruiting

Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial

Primary Open Angle Glaucoma | Ocular Hypertension

United States

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