Search clinical trials for: pharmacodynamic (PD)

Total 8378 results

Stanford University
David Drover, MD

Completed

Pharmacokinetic (PK) and Pharmacodynamic (PD) Modeling of Ampicillin and Gentamicin in Peripartum Patients

Drug Metabolism During Pregnancy

United States
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Fruquintinib and Albumin-paclitaxel Combined With or Without PD-1 Antibody in 2nd-line Treatment of G/GEJ Adenocarcinoma

Gastric Cancer
Beijing Tongren Hospital

Not yet recruiting

Maintenance Therapy With Anti-PD-1 Antibody for Patients With NK/T-cell Lymphoma

Extranodal NK/T-cell Lymphoma, Nasal Type
Wu Jun

Recruiting

Efficacy and Safety of Fruquintinib in Combination With PD-1 Inhibitors as First-line Maintenance Therapy for Advanced HER-2 Negative Gastric Cancer: a Single-arm, Prospective, Exploratory Clinical Study

Gastric Cancer

China
Sichuan Academy of Medical Sciences

Recruiting

Exercise Improves Gastrointestinal Function in Peritoneal Dialysis Patients

Quality of Life | Chronic Kidney Diseases | Peritoneal Dialysis | Exercise | Gastrointestinal Function

China
Rigshospitalet, Denmark
Odense University Hospital; Zealand University Hospital

Not yet recruiting

Enhancing Referral Decision-making for Advanced Treatment in Parkinson's Disease Through Objective Measurements and Patient Reported Outcomes. (PD-DigiCare)

Parkinson Disease

Denmark
Université Catholique de Louvain

Recruiting

Gait Control in Parkinson Disease (GAIT-PD)

Parkinson Disease

Belgium
Molnlycke Health Care AB
Syntactx

Not yet recruiting

A Safety and Performance PMCF Investigation of the Avance® Solo NPWT System in Surgically Closed Incisions (ASOLO-SCI)

Surgical Wound | Surgical Incision | Surgical Wound Dehiscence | Incision, Surgical | Surgical Wound, Recent
Sun Yat-sen University

Recruiting

Peritoneal Dialysis Registration System (PERSIST)

ESRD | Disorders Associated With Peritoneal Dialysis

China
University of South Florida

Completed

Solifenacin Succinate (VESIcare) for the Treatment of Overactive Bladder in Parkinson's Disease (URGE-PD)

Overactive Bladder in Parkinson's Disease

United States
wenbinlu

Unknown

Study for Perioperative Neurocognitive Disorders After Deep Brain Stimulation Surgery for Parkinson's Disease

Neurocognitive Disorders

China
Giancarlo Comi

Completed

Repetitive Transcranial Magnetic Stimulation With H-coil in Parkinson's Disease (rTMS-PD) (rTMS-PD)

Parkinson Disease

Italy
Peking University First Hospital

Completed

Different Retraining Methods vs Usual Care on the Prevention of Peritonitis in Peritoneal Dialysis

Peritonitis

China
Hebei Medical University

Unknown

Gingiva Mesenchymal Stem Cells Treatment of Chronic Periodontitis

Periodontitis

China
The Parkinson's Institute
Teva Neuroscience, Inc.

Unknown

A Study Assessing Change in Sense of Smell After Rasagiline Use in Parkinson's Patients (PD-SOAR)

Parkinson's Disease

United States
The Hong Kong Polytechnic University

Unknown

Effects of an Innovative Balance Training Programme in Enhancing Postural Control and Reducing Falls in Patients With Parkinson's Disease

Parkinson's Disease

China
Mannkind Corporation

Completed

Healthy Normal Volunteers Looking at Exposure and Effects of Multiple Doses of Technosphere® Insulin (TI) Using the Gen2C Inhaler

Healthy

United States
Nanjing Leads Biolabs Co.,Ltd

Recruiting

Evaluation of LBL-019 Monotherapy or Combined With Anti-PD-1 Antibody in the Treatment of Advanced Malignant Tumors

Advanced Malignant Tumors

China
NorthShore University HealthSystem
GE Healthcare

Completed

Imaging Biomarkers of Delayed Sequelae in Trauma Brain Injury

Parkinson's Disease | Traumatic Brain Injury

United States
Beth Israel Deaconess Medical Center
Merz Pharmaceuticals

Withdrawn

Incobotulinum Toxin A for Sialorrhea in Parkinson's Disease (PD)/Parkinsonism and Amyotrophic Lateral Sclerosis (ALS) (Xeomin)

Parkinson Disease | Amyotrophic Lateral Sclerosis

United States
Merck Sharp & Dohme LLC

Terminated

Study of MK-1697 in Participants With Advanced Solid Tumors (MK-1697-001)

Neoplasms | Head and Neck Neoplasms | Colorectal Neoplasms

Australia, Hong Kong
Centocor, Inc.

Completed

A Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of Golimumab in Patients With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States
Pfizer

Completed

A Study To Investigate The Absorption, Metabolism And Excretion Of [14C] PD 0200390 In Six Healthy Male Volunteers

Insomnia

United States
University of Miami

Recruiting

PRP for Treatment of Peyronie's Disease

Sexual Dysfunction, Physiological | Genital Diseases, Male | Peyronie Disease | Sexual Dysfunction Male

United States
Fox Chase Cancer Center
Genentech, Inc.

Active, not recruiting

Clinical Trial of Atezolizumab With Paclitaxel, Trastuzumab, and Pertuzumab in Patients With Metastatic HER-2 Positive Breast Cancer

HER2-positive Breast Cancer

United States
City, University of London

Completed

Distant Delivery of a Mindfulness-based Intervention for People Affected by Parkinson's Disease (MindPD)

Parkinson's Disease

United Kingdom
Io Therapeutics

Completed

Study of IRX4204 for Treatment of Early Parkinson's Disease

Parkinson's Disease

United States
Depomed

Completed

Study in Advanced Parkinson's Disease Patients With Predictable Motor Fluctuations

Parkinson's Disease | Motor Fluctuations

United States
Rajesh Pahwa, MD
GlaxoSmithKline

Completed

Pramipexole Conversion to Ropinirole Controlled Release (CR)

Parkinson Disease

United States
Case Comprehensive Cancer Center

Completed

Axitinib Given on an Individualized Schedule for Metastatic Renal Cell Cancer

Metastatic Renal Cell Cancer

United States
Azienda Ospedaliera di Padova

Unknown

Everolimus in de Novo Liver Transplantation: a Multicentre Randomized Study (EPOCAL)

Liver Diseases | Liver Failure | Liver Cirrhosis | Liver Neoplasms

Italy
Helios Albert-Schweitzer-Klinik Northeim

Unknown

Serum Parameter Prior and After EUS-guided Fine Needle Aspiration of the Pancreas

Pancreatitis

Germany
Fudan University

Unknown

Endostar Combined With IP Second-line Treatment of Advanced Esophageal Squamous Cell Carcinomas

Esophageal Squamous Cell Carcinoma

China
University of Jena

Unknown

Investigations on the Effect of Kale on the Lipid Status (HypocholKale)

Effects of Kale Ingredients on Lipid Status Parameter

Germany
Heidelberg University

Unknown

Molecular Determinants for Therapy Response on Renal Cell Carcinoma (MORE)

Renal Cell Carcinoma

Germany
Johann Wolfgang Goethe University Hospital

Unknown

Analysis of Palliative Surgery in View of Quality of Life and Prognosis

Quality of Life | Cancer

Germany
Chinese PLA General Hospital

Recruiting

Chidamide+Decitabine Plus Anti-PD-1 Antibody in PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma.

PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma

China
Changhai Hospital
National Natural Science Foundation of China

Completed

PD-1/PD-L1 Pathway Study on Septic Patients

Sepsis
Beth Israel Deaconess Medical Center

Completed

Quercetin PK/PD Study in Healthy Adults and Patients With Hypercoagulable States (PK/PD)

Healthy

United States
Eli Lilly and Company

Active, not recruiting

A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors (PACT)

Pancreatic Cancer | Solid Tumor | Cutaneous Melanoma | Microsatellite Instability-High (MSI-H) Solid Tumors | Breast Cancer (HR+HER2-)

Belgium, Spain, Korea, Republic of, United States, Taiwan, France, Canada
PDC*line Pharma SAS

Active, not recruiting

Safety, Immunogenicity and Preliminary Clinical Activity Study of PDC*lung01 Cancer Vaccine in NSCLC

Non Small Cell Lung Cancer

Belgium, France, Netherlands, Germany, Poland
Ono Pharmaceutical Co. Ltd

Suspended

Safety, Tolerability, PK, PD and Preliminary Efficacy of ONO-4685

Plaque Psoriasis

United Kingdom, Moldova, Republic of, Romania
Pfizer

Completed

Study In Healthy Adult Volunteers To Evaluate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of PF-04427429

Healthy

Belgium
BeiGene

Active, not recruiting

Safety and Preliminary Effectiveness of BGB-A445 in Combination With Tislelizumab in Participants With Advanced Solid Tumors

Non Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma (HNSCC) | Nasopharyngeal Carcinoma (NPC)

Canada, Australia, New Zealand, Korea, Republic of, United States, Malaysia, Thailand
Merck Sharp & Dohme LLC

Active, not recruiting

Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/KEYNOTE-667)

Hodgkin Lymphoma

United States, Brazil, Colombia, Czechia, France, Germany, Greece, Guatemala, Italy, Korea, Republic of, Mexico, Netherlands, Slovakia, South Africa, Spain, United Kingdom
University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

NET-PD LS-1 Creatine in Parkinson's Disease

Parkinson's Disease

United States, Canada
Changhai Hospital

Not yet recruiting

DV Combined With PD-1 and Platinum-based First-line Treatment in Patients With HER2 IHC2+/3+ ESCC

HER-2 Protein Overexpression | Esophageal Squamous Carcinoma
Merck Sharp & Dohme LLC

Terminated

Intratumoral/Intralesional Administration of MK-4621/JetPEI™ With or Without Pembrolizumab in Participants With Advanced/Metastatic or Recurrent Solid Tumors (MK-4621-002)

Advanced Solid Tumors

France, Germany, Spain, United Kingdom
Agenus Inc.

Withdrawn

AGEN2034 & AGEN1884 in Patients With Recurrent, Inoperable Angiosarcoma

Angiosarcoma
Second Military Medical University

Unknown

Immunotherapy Using Pluripotent Killer-Programmed Cell Death 1 (PIK-PD-1) Cells for the Treatment of Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

China

Search clinical trials for: pharmacodynamic (PD)

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