Search clinical trials for: Integrase inhibitors

Total 64330 results

Bristol-Myers Squibb
Merck Sharp & Dohme LLC

Terminated

Phase IIB Pilot of Atazanavir + Raltegravir (SPARTAN)

HIV

Argentina, United States, France
ViiV Healthcare
Shionogi

Completed

GSK1349572 Drug Interaction With Etravirine and Either Darunavir/Ritonavir or Lopinavir/Ritonavir

Healthy Volunteer

United States
Abbott
Merck Sharp & Dohme LLC

Completed

Study Comparing Lopinavir/Ritonavir (LPV/r) + Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF) With a Nucleoside Sparing Regimen Consisting of Lopinavir/Ritonavir + Raltegravir (RAL) (PROGRESS)

Human Immunodeficiency Virus Infection

United States, Canada, France, Italy, Poland, Puerto Rico, Spain
Angela Kashuba, PharmD
Merck Sharp & Dohme LLC

Completed

Study to Characterize the Pharmacokinetics of Raltegravir in the Gastrointestinal (GI) Tract of Healthy Male Volunteers

Healthy Volunteer

United States
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

Drug Interaction Study Between Dolutegravir and Prednisone

Infection, Human Immunodeficiency Virus

United States
Stanford University

Completed

RAL-eve Study: Raltegravir Substitution Study

HIV Infections

United States
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Terminated

MK-0518 Intensification And HDAC Inhibition In Depletion Of Resting CD4+ T Cell HIV Infection

HIV Infections

United States
Kristine Patterson, MD
Merck Sharp & Dohme LLC

Completed

A Pilot Study to Characterize the Pharmacokinetics of Raltegravir in the Cervicovaginal Fluids of HIV-infected Women

HIV | AIDS

United States
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

Relative Bioavailability Study of a Pediatric Granule Formulation of Dolutegravir

Infections, Human Immunodeficiency Virus and Herpesviridae

United States
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

Relative Bioavailability Study of Two New Dolutegravir/Abacavir/Lamivudine Fixed Dose Combination Tablets

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
Hoffmann-La Roche
Trimeris

Terminated

A Study of Fuzeon (Enfuvirtide) With an Integrase Inhibitor Plus Optimized Background in Treatment-Experienced HIV-1 Infected Patients (AMICI)

HIV Infections

United States, Puerto Rico
St. James's Hospital, Ireland

Unknown

Safety and Efficacy Study Comparing Raltegravir to a Protease Inhibitor in Treatment-naïve, HIV/Hepatitis C Drug Users

HIV Infections | Hepatitis C

Ireland
Saint Michael's Medical Center
Abbott

Completed

Safety Study of Lopinavir/Ritonavir With Raltegravir in HIV-infected Patients

HIV Infections

United States
Tibotec Pharmaceuticals, Ireland
Raltegravir is provided by Merck.

Completed

TMC278-TiDP6-C153 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC278 and Raltegravir

HIV Infections
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

A Study to Investigate the Pharmacokinetics, Safety and Tolerability of GSK1349572 (Dolutegravir, DTG) in Healthy Japanese Subjects

Infection, Human Immunodeficiency Virus

United States
Centers for Disease Control and Prevention, China
Merck Sharp & Dohme LLC

Unknown

A Trial to Compare Raltegravir Versus Nevirapine as Anchor Drug for HIV+ Chinese IDUs on Methadone Maintenance

HIV Infections | HIV

China
Doroana, Maria Manuela, M.D.
Merck Sharp & Dohme LLC; Eurotrials Brasil Consultores Cientificos Ltda

Completed

Raltegravir With Optimized Background Therapy (OBT) in Multiple Experienced HIV-infected Patients

HIV Infections
Central Institute of Epidemiology, Moscow, Russia
Merck Sharp & Dohme LLC

Unknown

Raltegravir + Lamivudine/Abacavir in HIV/Tuberculosis Co-Infected Patients

HIV Infections | Tuberculosis

Russian Federation
East Carolina University

Unknown

Effect of a Non-tenofovir, Non-efavirenz-based HIV Regimen on Bone Density and Vitamin D Levels in African-American Patients With HIV Infection

HIV
Yunnan AIDS Care Center

Unknown

Safety and Efficacy of Raltegravir+TDF+3TC in HBV/HIV Co-infected Patients

HIV Infections | HBV Coinfection

China
Hospitales Universitarios Virgen del Rocío

Completed

Plasma and Intracellular Concentrations of Raltegravir and Etravirine Administered Once Daily (RAET)

HIV Infections | HIV-1 Infection

Spain
GlaxoSmithKline

Completed

A Healthy Volunteer And Patient Study To Assess The Safety, Tolerability And Pharmacokinetics Of GSK1265744

HIV Infection

United States
GlaxoSmithKline

Completed

GSK1349572 First Time in Human Study

Healthy Subjects

United States
GlaxoSmithKline

Completed

GSK1349572 Drug Interaction With Tenofovir

Healthy Subjects

United States
French National Agency for Research on AIDS and...
Merck Sharp & Dohme LLC; Janssen-Cilag Tibotec

Completed

Clinical Trial to Assess the Efficacy of Darunavir/Ritonavir (DRV/r), Etravirine (ETV) and Raltegravir (MK-0518) in HIV Patients With Resistant Viruses (ANRS139 TRIO)

HIV Infections

France
Shanghai Public Health Clinical Center

Unknown

Efficacy and Safety of Raltegravir (RAL) in Treatment-experienced HIV-1 Infected Adult Chinese Patients

HIV

China
GlaxoSmithKline
Shionogi

Completed

GSK1349572 Drug Interaction Study With Protease Inhibitors

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
GlaxoSmithKline

Completed

DDI Study of Etravirine and GSK1265744

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
St Stephens Aids Trust

Completed

Raltegravir Insulin Sensitivity Study

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

Raltegravir and Ezetimibe PK Study

HIV

United Kingdom
Benaroya Research Institute
Sanofi

Completed

Borderline Resectable Pancreatic Cancer: Gemcitabine/Docetaxel and Oxaliplatin Based Chemo/RT

Pancreatic Cancer

United States
Hospital Clinic of Barcelona

Unknown

Effects of Raltegravir (Isentress®) on Lipid and Carbohydrate Metabolism and Mitochondrial Function in Healthy Volunteers (RALMET-VOLHCB)

Healthy Volunteers

Spain
Hospital Clinic of Barcelona

Completed

Switching From PI to RALtegravir in HIV Stable Patients (SPIRAL)

HIV Infections

Spain
Hospital Clinic of Barcelona

Unknown

Integrase Resistance Analysis in HIV Patients Who Interrupted Raltegravir Due to Incomplete Viral Suppression (RAL-dyn)

HIV Infection

Spain
Changi General Hospital
National University Hospital, Singapore; Merck Sharp & Dohme LLC

Completed

Comparison of Concentration-time Course of Plasma and Intracellular Raltegravir in Healthy Volunteers

Human Immunodeficiency Virus

Singapore
Fundación Huésped
Pfizer

Unknown

Maraviroc (Celsentri) With Raltegravir and Darunavir/Ritonavir for the Treatment of Triple Class Failure in Adult HIV-1 Infected Patients (TERCETO)

AIDS | HIV-1 Adults Patients | Triple Class Failure

Argentina
Bristol-Myers Squibb
Merck Sharp & Dohme LLC

Completed

DDI HV (ATV - Merck)

HIV Infections

United States
GlaxoSmithKline
Shionogi

Completed

Study to Assess Cardiac Conduction of GSK1349572

Healthy Subjects

United States
St Stephens Aids Trust

Completed

Pharmacokinetics (PK) Study of Once Daily Darunavir/Ritonavir and Twice and Once Daily Raltegravir in HIV-infected Subjects

HIV Infections

United Kingdom
University Hospital, Geneva
University Hospital, Basel, Switzerland; University of Lausanne Hospitals; University... and other collaborators

Unknown

Patient Preference, Sleep Quality, and Anxiety/Depression: A Comparison of Raltegravir and Efavirenz (Switch-ER)

HIV Infections | Sleep Disorders

Switzerland
St Stephens Aids Trust

Completed

Abacavir Pharmacokinetic Study in the Absence/Presence of Darunavir/Ritonavir or Raltegravir in HIV-infected Subjects

HIV

United Kingdom
GlaxoSmithKline
Shionogi

Completed

GSK1349572 Proton Pump Inhibitor Drug Interaction and Supratherapeutic Dose Study

Healthy Volunteer

United States
Hospital Carlos III, Madrid

Unknown

Simplification From Protease Inhibitors to Raltegravir (ODIS)

HIV Infections

Spain
GlaxoSmithKline
Shionogi

Completed

GSK1349572 Drug Interaction Study With Atazanavir/Ritonavir and Atazanavir

Healthy Volunteer

United States
GlaxoSmithKline
Shionogi

Completed

GSK1349572 Mass Balance Study

Healthy Volunteer

United States
GlaxoSmithKline
Shionogi

Completed

GSK1349572 Drug Interaction Study With Etravirine

Healthy Subjects

United States
GlaxoSmithKline
Shionogi

Completed

A Study to Evaluate the Effect of Antacid and Multivitamin and Mineral Tablet on the Study Drug GSK1349572 (DDI)

Healthy Volunteer

United States
Denver Infectious Disease Consultants, PLLC
GlaxoSmithKline

Unknown

Pilot Study With Isentress (Raltegravir) and Epzicom (Abacavir/Lamivudine) in Treatment Naive HIV-Infected Subjects (SHIELD)

HIV Infections

United States
Pfizer

Completed

Drug Interaction Study Between Raltegravir And UK-453,061

Healthy Volunteers

United States
Peter J. Ruane, M.D., Inc.

Unknown

Raltegravir and Atazanavir Replacing Current Suppressive Treatment Because of Side Effects in Current Treatment

HIV Infections

United States

Search clinical trials for: Integrase inhibitors

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