Search clinical trials for: severe

Total 8587 results

Eli Lilly and Company

Recruiting

A Study of LY3454738 in the Treatment of Adult Participants With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis

Taiwan, China, Canada, United States, Hungary, Mexico, Poland, Japan, Korea, Republic of
Janssen Research & Development, LLC

Recruiting

A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN) (AZALEA)

Hemolytic Disease of the Fetus and Newborn

Israel, Japan, Australia, United States, United Kingdom, Brazil
Valve Medical

Recruiting

FIH Study of the GEMINUS TAVI System in Patients With Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

Israel
Hellenic Institute for the Study of Sepsis

Recruiting

Assessing the Procalcitonin-guidance and Molecular-guided Diagnosis for Therapy of Severe Infections (the MODIFY Trial) (MODIFY)

Sepsis

Greece
Curacle Co., Ltd.

Not yet recruiting

Phase 2 Study of CU104 in Moderate-Severe Ulcerative Colitis (UC)

Ulcerative Colitis
NHS Greater Glasgow and Clyde
Fisher and Paykel Healthcare; LINET

Recruiting

High Flow Nasal Oxygen at Extubation for Adults Requiring a Breathing Tube for Treating Severe Breathing Difficulties (Pre-SAFEx)

Respiratory Insufficiency

United Kingdom
Marmara University

Recruiting

The Effects of Systemic Isotretinoin Treatment on Adrenal Steroid and Sex Hormones Level in Severe Acne Vulgaris

Acne Vulgaris

Turkey
Assistance Publique - Hôpitaux de Paris

Recruiting

Customized Antibiotic Treatment Duration Among Hospitalized Patients With Moderately Severe Community-Acquired Pneumonia (CAT-CAP)

Community-Acquired Pneumonia

France
Centre Hospitalier Universitaire de Nice

Recruiting

Contribution of an Antiviral Drug (Valaciclovir) in the Treatment of Generalized Periodontitis (Stage III or IV and Grade A, B or C): Prospective, Randomized and Double Blind Clinical Trial (HERPARO)

Periodontitis Chronic Generalized Severe

France
Université Catholique de Louvain

Recruiting

Impact of Omega 3 in Alcohol Use Disorder (W3-AUD)

Alcohol Use Disorder, Severe

Belgium
Peking Union Medical College Hospital

Recruiting

The Efficacy and Safety of Corticosteroids in Combination With Ruxolitinib in the Management of Checkpoint Inhibitor Pneumonia

Severe Checkpoint Inhibitor Pneumonitis

China
The First Affiliated Hospital with Nanjing Medical...
Novlead Inc.

Recruiting

A Clinical Study of Inhaled Nitric Oxide in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (NOVEL)

Chronic Obstructive Pulmonary Disease

China
Institut Pasteur
Hopital Universitaire Robert-Debre; Hospices Civils de Lyon; Centre Hospitalier... and other collaborators

Recruiting

Impact of Bacterial Expression and Immune Response in the Severity of Pertussis (PERT-SEVEREII)

Bordetella Pertussis, Whooping Cough

France
Academy of Nutrition and Dietetics
Hartford Hospital; University of New Mexico; Meals on Wheels Central Texas

Not yet recruiting

Essential Connections: Hospital to Community Impacting Malnutrition Outcomes in Older Adults

Malnutrition; Protein
Jinnah Postgraduate Medical Centre

Recruiting

Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortality (MUNI-SEP)

Septic Shock | Severe Sepsis | MODS

Pakistan
Bio Genuine (Shanghai) Biotech Co., Ltd.

Recruiting

Efficacy and Safety of BG2109 in Chinese Subjects With Endometriosis

Endometriosis | Moderate to Severe Endometriosis-associated Pain

China
Fondation Hôpital Saint-Joseph

Recruiting

Two-year Efficacy of Three Exercise Rehabilitation Strategies on Dyspnea in Patients Who Presented With Secondary Respiratory Distress Syndrome Secondary to Severe COVID-19 Pneumonia (RECOVER_FU)

COVID-19 | Dyspnea

France
Pfizer

Not yet recruiting

A Study on Paxlovid Once in the Market, to Observe Its Safety and Effectiveness in Patients Who Have a High Chance of Getting Severe COVID-19

COVID-19
Brain Trauma Foundation
The Cleveland Clinic; Weill Medical College of Cornell University; Uniformed... and other collaborators

Not yet recruiting

External Lumbar Drainage to Reduce ICP in Severe TBI: a Phase 1 Clinical Trial (ELASTIC)

Intracranial Hypertension | Severe Traumatic Brain Injury

United States
Hasan Kalyoncu University

Not yet recruiting

Reliability and Validity of the Turkish Version of the PedHAL

Hemophilia B | Hemophilia | Hemophilia A, Severe

Turkey
AbbVie

Recruiting

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy (Step-Up HS)

Hidradenitis Suppurativa

United States, Japan, Australia, Canada, Korea, Republic of, New Zealand, Puerto Rico, Spain, Austria, Italy, Bulgaria, Israel, Taiwan, Croatia, Hungary, Netherlands, Switzerland, Germany, Portugal, France, United Kingdom, Czechia, ... and more
CHU de Reims

Recruiting

Use of a New Method for the Microbiological Diagnosis of Severe Corneal Infection (ABCORFILM)

Infectious Keratitis | Microbial Keratitis | Corneal Infection

France
University of Texas Southwestern Medical Center

Recruiting

Mitoquinone/Mitoquinol Mesylate as Oral and Safe Postexposure Prophylaxis for Covid-19

COVID-19 | SARS-CoV Infection

United States
First People's Hospital of Hangzhou

Recruiting

Safety Study of Fenofibrate During Pregnancy

Severe Hypertriglyceridemia During Pregnancy

China
Shanghai Ninth People's Hospital Affiliated to...

Recruiting

Clinical Study of Allogeneic Adipovarian Active Protein in the Treatment of Severe Idiopathic Pulmonary Fibrosis (CEFFE-IPF)

Idiopathic Pulmonary Fibrosis

China
Del-Pest Central Hospital - National Institute...

Recruiting

Extracorporeal Photopheresis as a Possible Therapeutic Approach to Adults With Severe and Critical COVID-19 (COVID-ECP)

COVID-19

Hungary
Amgen

Recruiting

A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-ASCEND)

Atopic Dermatitis

United States, Japan, Korea, Republic of, Australia, Taiwan, Spain, Switzerland, Germany, Croatia, Austria, Bulgaria, France, Denmark, China, Netherlands, Hungary, Czechia, Poland, Brazil, Greece, Portugal, Italy, Finland, Argentina, Sl... and more
Assiut University

Not yet recruiting

Causes, Complications and Outcomes of Severe Acute Liver Disease Cases Admitted to Intensive Care Units

Acute Liver Disease
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

"Comparison of the Efficacy and Safety of Adalimumab to That of Tocilizumab in Severe Uveitis of Behçet's Disease" (UVB)

Behcet's Uveitis
Xiaotong Hou

Not yet recruiting

A Pilot Study of Sivelestat Sodium to Shorten Mechanical Ventilation in Acute Aortic Dissection

Acute Aortic Dissection

China
Protembis GmbH

Recruiting

The PROTEMBO Trial

Severe Aortic Valve Stenosis

United States
Juno Therapeutics, Inc., a Bristol-Myers Squibb...
Bristol-Myers Squibb Services Unlimited Company

Recruiting

A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases

Systemic Lupus Erythematosus | Systemic Sclerosis | Idiopathic Inflammatory Myopathy

United States, Belgium, France, Spain, Germany, Italy
Berinstein, Jeffrey

Recruiting

A Trial for Acute Severe Ulcerative Colitis

Ulcerative Colitis Acute

United States
Shanghai Zhongshan Hospital

Not yet recruiting

Surgeons' Mental Distress and Risks After Severe Complications Following Emergency Surgery

Mental Health
University Hospital, Toulouse

Not yet recruiting

Interest of Oxytocin as an Adjuvant Treatment of Psycho-educational Measures in Challenging Behaviors in Children With Autism Spectrum Disorders and Moderate to Severe Intellectual Disability: Feasibility and Safety Study. (OT-DEFI)

Autism Spectrum Disorder

France
University of Nebraska

Recruiting

Comparison of Nasopharyngeal Swab v. Nasopharyngeal Saline Wash or Saliva Collection in Testing for Respiratory Viruses

Respiratory Tract Infections

United States
First Hospital of China Medical University
China-Japan Friendship Hospital

Not yet recruiting

Real World Study on the Efficacy and Safety of Apremilast in Chinese Patients With Moderate to Severe Plaque Psoriasis, a Multi Center, Prospective, Observational Trial（REACT）

Psoriasis

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Cannabidiol as an add-on Treatment During Inpatient Alcohol Cessation in Patients With Severe Alcohol Use Disorder: a Phase ii Trial (CBD-OH)

Severe Alcohol Use Disorder (DSM 5)

France
Numab Therapeutics AG
Kaken Pharmaceutical Co., Ltd.

Recruiting

Evaluation of NM26-2198 in Healthy Subjects and in Patients With Moderate-to-severe Atopic Dermatitis (AD)

Atopic Dermatitis

Germany, Canada, United States, Poland
Xuanwu Hospital, Beijing

Recruiting

Osmotic Therapy for Patients With Severe Subarachnoid Hemorrhage (OSMO-SAH)

Subarachnoid Hemorrhage, Traumatic

China
Affiliated Cancer Hospital & Institute of Guangzhou...

Recruiting

Predictive Study on Acute Radiation Induced Oral Mucositis in Nasopharyngeal Carcinoma Patients

Nasopharyngeal Carcinoma by AJCC V8 Stage | Radiation Induced Mucositis

China
Emory University

Recruiting

Arginine Replacement Therapy in COVID-19 (ART-COVID19)

COVID-19

United States
Proteocyte Diagnostics Inc.
The University of Texas Health Science Center, Houston; University of Alabama... and other collaborators

Recruiting

Evaluation of Oral Potentially Malignant Disorders (OPMDs) With STRATICYTE™

Mouth Diseases

United States
Australian and New Zealand Intensive Care Research...

Recruiting

PRECISION-TBI - An Observational Study of Patients With Moderate to Severe Traumatic Brain Injury

Trauma, Brain

Australia
Apreo Health, Inc.

Recruiting

First in Human Study to Assess an Implant to Treat Severe Emphysema (BREATHE-1)

Emphysema or COPD

Australia
Fei Gao

Not yet recruiting

Clinical Study on Prognosis of Patients With Severe NPDR Undergoing Vitrectomy

Non Proliferative Diabetic Retinopathy(NPDR)

China
89bio, Inc.

Recruiting

To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia (ENTRUST)

Severe Hypertriglyceridemia

United States, Bulgaria, Canada, Latvia, Spain, Austria, Belgium, Czechia, Georgia, Hungary, Poland, Puerto Rico, Argentina, Chile, France, Germany, United Kingdom
Heinrich-Heine University, Duesseldorf
German Research Foundation; University Bonn; University Cologne; Collaborative...

Not yet recruiting

Biomarkers and Mechanisms of Disease Progression and Outcome of Aortic Stenosis in Humans

Disease Progression | Aortic Stenosis | Genetics | Pathogenesis | Aortic Valve Calcification | Imaging

Germany
Centre Hospitalier National d'Ophtalmologie des...
Fondation Ophtalmologique Adolphe de Rothschild

Not yet recruiting

Large Cohort of 1000 Patients With Severe Myopia (MyoCo1000)

Myopia, Severe
Incyte Corporation

Recruiting

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma

Moderate to Severe Asthma

Korea, Republic of, United States, Spain, Poland, Japan, Canada, Germany, Belgium, Argentina

Search clinical trials for: severe

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