Clinical Trials Sponsored by Ottawa Hospital Research Institute

Total 3943 results

Ottawa Hospital Research Institute
Ontario Institute for Cancer Research; Intensity Therapeutics, Inc.

Recruiting

INVINCIBLE TRIAL: Intratumoral INT230-6 in Breast Cancer

Breast Cancer

Canada
Ottawa Hospital Research Institute
The Physicians' Services Incorporated Foundation; The Ottawa Hospital Academic...

Completed

Evaluation of a Interdisciplinary Pain Program Among Patients With Chronic Pain and Frequent Emergency Department Visits (CIPAP)

Chronic Pain | Interdisciplinary Communication | Peer Review, Health Care

Canada
Ottawa Hospital Research Institute
The Ottawa Hospital Academic Medical Association; Canadian Association of Emergency...

Completed

High-dose vs. Standard-dose Cephalexin for Cellulitis

Cellulitis

Canada
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Institute for Clinical Evaluative...

Completed

Assessing Dementia Risk in the Community: The Dementia Population Risk Tool (DemPoRT)

Dementia
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Institute for Clinical Evaluative...

Completed

Risk Evaluation for Support: Predicting Elder Life in the Community Tool (RESPECT) (RESPECT)

Death
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial in Patients With Permanent Atrial Fibrillation (RAFT-PermAF)

Atrial Fibrillation | Heart Disease | Congestive Heart Failure

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Timing of Coronary Artery Bypass Surgery Among Patients With Acute Coronary Syndromes Initially on Ticagrelor (RAPID CABG)

Acute Coronary Syndrome

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Rubidium-82 - An Alternative Radiopharmaceutical for Myocardial Imaging(Rb-ARMI) (Rb-ARMI)

Coronary Artery Disease

Canada
Ottawa Hospital Research Institute
The Physicians' Services Incorporated Foundation

Recruiting

Nasal Packing Following Endoscopic Endonasal Pituitary Resection

Pituitary Tumor

Canada
Ottawa Hospital Research Institute
The Physicians' Services Incorporated Foundation

Completed

Blood Pressure Measurement: Should Technique Define Targets?

Hypertension

Canada
Ottawa Hospital Research Institute
The Kidney Foundation of Canada

Completed

Access Creation for Hemodialysis: Association With Structural Changes of the Heart

Arteriovenous Fistula | Left Ventricular Hypertrophy | Arteriovenous Graft | Brain Natriuretic Peptide

Canada
Ottawa Hospital Research Institute
The Ontario Spor Support Unit

Completed

A Pragmatic Evaluation of the Canadian C-Spine Rule by Paramedics

Neck Injuries

Canada
Ottawa Hospital Research Institute
CIHR Canadian HIV Trials Network

Terminated

Penicillin Therapeutic Drug Monitoring in the Treatment of Infectious Syphilis.

Syphilis | Primary Syphilis | Secondary Syphilis | Early-Latent Syphilis

Canada
Ottawa Hospital Research Institute
The Physicians' Services Incorporated Foundation

Completed

Weaning And Variability Evaluation (WAVE) (WAVE)

Extubation

Canada
Ottawa Hospital Research Institute
The Physicians' Services Incorporated Foundation

Completed

Measuring Kidney Function in Kidney Transplantation

Renal Transplant

Canada
Ottawa Hospital Research Institute
Cardiac Arrhythmia Network of Canada

Completed

Decreasing Hospital Admissions From the ED for AAFF (RAFF-3)

Atrial Fibrillation | Atrial Flutter

Canada
Ottawa Hospital Research Institute
CSL Behring; Grifols Biologicals, LLC

Completed

Ig PRx in AECOPD: Pilot Study

Chronic Obstructive Pulmonary Disease

Canada
Ottawa Hospital Research Institute
CIHR Canadian HIV Trials Network

Withdrawn

Improving Fibrosis Outcomes With Metformin

HIV Infection | Hepatitis C

Canada
William Osler Health System
McMaster University; University of Toronto; Ottawa Hospital Research Institute; The Ottawa Hospital and other collaborators

Not yet recruiting

Implementation of RELIEF for Patients With Palliative Care Needs

Palliative Care
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

Canadian Study of Arterial Inflammation in Patients With Diabetes and Vascular Events: EvaluatioN of Colchicine (CADENCE)

Cardiovascular Diseases | Inflammation | Diabetes | Atherosclerosis

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Rhythm Control - Catheter Ablation With or Without Anti-arrhythmic Drug Control of Maintaining Sinus Rhythm Versus Rate Control With Medical Therapy and/or Atrio-ventricular Junction Ablation and Pacemaker Treatment for Atrial Fibrillation (RAFT-AF)

Heart Failure | Atrial Fibrillation

Canada, Taiwan, Sweden, Brazil
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

A Pharmacodynamic Study of a Personalized Strategy for P2Y12 Inhibition Versus Ticagrelor in Reducing Ischemic and Bleeding Risk (RAPID MANAGE)

Acute Coronary Syndrome | Percutaneous Coronary Intervention

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

MARINER Trial: Multiparametric Cardiac PET for CAV Surveillance After Heart Transplantation

Cardiac Allograft Vasculopathy

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

AERIAL Trial: Antiplatelet Therapy in Heart Transplantation

Cardiac Allograft Vasculopathy | Heart Transplant

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

Cardiac Sarcoidosis Randomized Trial (CHASM-CS-RCT)

Sarcoidosis | Cardiac Sarcoidosis

United States, Canada, United Kingdom, Japan
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments (INITIATE)

Nicotine Dependence, Cigarettes | Nicotine Withdrawal

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline Chemotherapy

Heart Failure

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Bridge or Continue Coumadin for Device Surgery Randomized Controlled Trial (BRUISECONTROL)

Hematoma

Canada, Brazil
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

A Study of 123I-CMICE-013 Radiopharmaceutical in Healthy Volunteers (CMICE)

Coronary Artery Disease

Canada
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Canadian Breast Cancer Foundation

Completed

The Effect of an Inter-Disciplinary Program, Including MBSR, in Breast Cancer Survivors With Chronic Neuropathic Pain (InDepth)

Quality of Life | Breast Cancer | Chronic Pain | Painful Neuropathy | Worries; Pain or Disability

Canada
Montreal Heart Institute
Ottawa Heart Institute Research Corporation

Completed

LVEF Prediction During ACS Using AI Algorithm Applied on Coronary Angiogram Videos (CathEF)

Acute Coronary Syndrome | Left Ventricular Dysfunction

Canada
Ottawa Hospital Research Institute
The Ottawa Hospital Academic Medical Association; Network of Canadian Emergency...

Enrolling by invitation

High-dose Cephalexin for Cellulitis (HI-DOCC) (HI-DOCC)

Cellulitis

Canada
Ottawa Hospital Research Institute
McMaster University; The Ottawa Hospital; Hamilton Health Sciences Corporation; Sinai Health System

Completed

Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ventilation (PROACTIVE)

Critical Illness | COVID | Sedation | Mechanical Ventilation

Canada
Children's Hospital of Eastern Ontario
McGill University; Ottawa Hospital Research Institute; The Ottawa Hospital; Children...

Completed

Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level (HICCUPS 2)

Vitamin D Deficiency | Heart Defects, Congenital | Thoracic Surgery | Pediatric Disorders

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR); Ottawa Hospital Research Institute and other collaborators

Completed

Promoting Organ Donor Registration in Family Physician Offices

Organ Donation | Registration for Deceased Organ Donation

Canada
Mayo Clinic
Ottawa Heart Institute Research Corporation

Recruiting

Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion (CAPITAL-RAPTOR)

Radial Artery Occlusion

United States
Ottawa Heart Institute Research Corporation
GE Healthcare

Recruiting

Multi-Center Evaluation of Feasibility of SPECT Measurement of Myocardial Blood Flow and Reserve

Coronary Artery Disease

Canada, Germany, Belgium, Japan, Singapore
Ottawa Heart Institute Research Corporation
Genome Canada

Recruiting

Predicting Development of SCAF in Device Patients

Atrial Fibrillation

Canada
Ottawa Heart Institute Research Corporation
GE Healthcare

Recruiting

Cadmium-zinc-telluride (CZT) Imaging of Myocardial Blood Flow (MBF) (SPECT MBF) (SPECT MBF)

Coronary Heart Disease

Canada
Ottawa Heart Institute Research Corporation
StepsCount Inc

Completed

Feasibility and Usability of a Pedometer in a Cardiovascular Disease Prevention Program for French-speaking Canadians (PiezoRx)

Cardiovascular Disease

Canada
David Birnie

Completed

The Ottawa AF Cardioversion Protocol

Atrial Fibrillation

Canada
Ottawa Heart Institute Research Corporation
GE Healthcare

Completed

123I-mIBG SPECT Imaging

Coronary Artery Disease | Heart Failure

Canada
Ottawa Heart Institute Research Corporation
Sanofi; Pfizer

Completed

A Study Comparing Standard Care for Diabetes to Case-Managed Care for Diabetes in Patients With Coronary Artery Disease

Coronary Disease | Diabetes Mellitus, Type 2

Canada
Ottawa Heart Institute Research Corporation
Edwards Lifesciences

Completed

Transcranial Doppler (TCD) Assessment During Early Anti-thrombotic Therapy After Bioprosthetic Aortic Valve Replacement (Tissue-Valve)

Aortic Valve Disease

Canada
Ottawa Hospital Research Institute
University of Toronto; University of Western Ontario, Canada; University of Ottawa

Active, not recruiting

Adverse Long-term Consequences of Sleep Disordered Breathing: The Ottawa Hospital (TOH) Sleep Database

Sleep Apnea Syndromes | Restless Legs Syndrome | Opioid Use | Risk Factors | Prognosis | Periodic Limb Movement Sleep Disorder | Polysomnography | Sleep Arousal Disorders

Canada
Ottawa Hospital Research Institute
University Hospital, Geneva; Leiden University Medical Center

Unknown

Safely Ruling Out Deep Vein Thrombosis in Pregnancy With the LEFt Clinical Decision Rule and D-Dimer (LEaD)

Pregnancy | Deep Vein Thrombosis

Netherlands, Canada, Switzerland, United States
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR); Medtronic

Completed

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial (RAFT)

Heart Failure, Congestive

Canada, Netherlands, Australia, Turkey, Denmark, Germany, Belgium
The Hospital for Sick Children
Ottawa Hospital Research Institute; Women's College Hospital

Not yet recruiting

ONLOOP Trial: Evaluating a New Surveillance and Support System for Survivors of Childhood Cancer in Ontario

Heart Diseases | Cancer | Breast Cancer | Colorectal Cancer | Survivorship | Secondary Cancer
Ottawa Hospital Research Institute
The Ottawa Hospital Academic Medical Association; The Academy for Innovation...

Completed

Does Instruction on Cognitive Aid Use Improve Performance and Retention of Skills?

Long-term Retention of Advanced Cardiac Life Support Skills

Canada
Ottawa Hospital Research Institute
Heart and Stroke Foundation of Ontario

Completed

Sympathetic Activity in Patients With End-stage Renal Disease on Peritoneal Dialysis (SAPD)

End-stage Renal Disease (ESRD) | Kidney Disease

Canada

Clinical Trials Sponsored by Ottawa Hospital Research Institute

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