Clinical Trials Sponsored by Children's Hospital and Health Center

Total 15475 results

Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Congenital Heart Disease GEnetic NEtwork Study (CHD GENES) (CHD GENES)

Congenital Heart Defects

United States, United Kingdom
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome (DYMOSA)

Obstructive Sleep Apnea | Down Syndrome

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Using MRI to Observe Lung Changes in Infants With CF Compared to Infants Without CF (MRIinfantCF)

Cystic Fibrosis

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mechanisms Mediating Cardiovascular Disease in Children With Obstructive Sleep Apnea

Heart Diseases | Cardiovascular Diseases | Sleep Apnea Syndromes | Lung Diseases | Hypertension
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Realizing Effectiveness Across Continents With Hydroxyurea (REACH)

Children | Sickle Cell Disease

Congo, The Democratic Republic of the, Angola, Kenya, Uganda
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Monitoring Response to Orkambi in Cystic Fibrosis Lung Disease by Inhaled Xenon MRI

Cystic Fibrosis

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100

Fanconi Anemia

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Adolescent Controlled Text Messaging to Improve Asthma Medication Adherence in Primary Care (ACT Me)

Persistent Asthma

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Research Study for Children About Heart Changes and Obstructive Sleep Apnea (OSA)

Obstructive Sleep Apnea

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Dexamethasone to Treat Acute Chest Syndrome in People With Sickle Cell Disease

Anemia, Sickle Cell

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

CV Disease in Adolescents With Type 2 Diabetes

Heart Diseases | Cardiovascular Diseases | Obesity | Diabetes Mellitus

United States
Children's Hospital Medical Center, Cincinnati
University of Pittsburgh; Vanderbilt University Medical Center; Children's Hospital... and other collaborators

Not yet recruiting

HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis (HeartGPS)

Depression, Postpartum | Neurodevelopmental Disorders | Heart Defects, Congenital | Trauma, Psychological | Anxiety in Pregnancy

United States, Australia
The Hospital for Sick Children
Canadian Institutes of Health Research (CIHR); Children's Hospital of Eastern... and other collaborators

Completed

Magnesium Nebulization Utilization in Management of Pediatric Asthma (MAGNUMPA)

Acute Asthma

Canada
Duke University
Centers for Disease Control and Prevention; Children's Hospital Medical Center...

Completed

Safety and Immunogenicity of Simultaneous Tdap and IIV in Pregnant Women (Tdap/IIV)

Pregnancy

United States
Children's Hospital Medical Center, Cincinnati
Uganda Heart Institute

Recruiting

Accelerating Delivery of rheUmatic Heart Disease Preventive iNterventions in Northern Uganda (ADUNU)

Rheumatic Heart Disease

Uganda
Children's Hospital Medical Center, Cincinnati
Uganda Heart Institute

Recruiting

GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial

Rheumatic Heart Disease

Uganda
Shanghai Children's Hospital
Tongji Hospital; Shengjing Hospital; Zunyi Medical College; Shanxi Provincial Maternity... and other collaborators

Not yet recruiting

Analysis of Risk Factors for Children With Heterochronous Indirect Hernia

Laparoscopic Surgery | Child, Only | Inguinal Hernia, Direct
Children's Hospital Medical Center, Cincinnati
Uganda Heart Institute

Completed

Train the Trainer Curriculum to Scale up AI Supported Echo for RHD Screening in a Public Health System (ADD-RHD 2B)

Rheumatic Heart Disease

Uganda
Children's Hospital Medical Center, Cincinnati
Uganda Heart Institute

Completed

Case Management and Peer Support Groups for Prophylaxis Adherence in Rheumatic Heart Disease (CAMPS)

Rheumatic Heart Disease

Uganda
Shanghai Children's Hospital
Children's Hospital affiliated to Chongqing Medical University; Xuzhou maternal...

Not yet recruiting

NGS in the Diagnosis of Neonatal Diseases

Premature Infants | NICU Infants | Conventional NBS-positive Infants
Children's Hospital Medical Center, Cincinnati
American Heart Association

Completed

TRPV2 Agonists in the Fontan Circulation

Fontan

United States
Health Science Center of Xi'an Jiaotong University
Guangzhou Women and Children's Medical Center

Unknown

Burden of Invasive Group B Streptococcal Disease in Infants and Resistance Surveillance in China

Invasive Group B Streptococcal Disease

China
Tianjin Women and Children's Health Center
Pennington Biomedical Research Center; Tianjin Medical University

Completed

Randomized Translational Study to Examine the Effects of Shared Care in Management of Gestational Diabetes

Gestational Diabetes Mellitus

China
Wei Yu Yao
KK Women's and Children's Hospital

Completed

Supreme LMA and Endotracheal Intubation Use in Caesarean Section

Complications; Cesarean Section
Zhuhai Center for Maternal and Child Health Care
Children's Hospital of Chongqing Medical University

Recruiting

Hyperbilirubinemia in Full-term Neonates (HFN)

Hyperbilirubinemia, Neonatal

China
Seattle Children's Hospital
University of Washington; National Center for Complementary and Integrative...

Unknown

Mind-Body Interventions to Mitigate Effects of Media Use on Sleep in Early Adolescents (Sleepazoid)

Sleep Initiation and Maintenance Disorders

United States
Boston Children's Hospital
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

Treatment Advocacy Intervention for HIV-Positive African Americans (TA)

HIV

United States
Bloodworks
Oregon Health and Science University; Seattle Children's Hospital; Providence...

Unknown

Comparison of Ideal vs. Actual Weight Base Factor Dosing

Hemophilia A

United States
Boston Children's Hospital
Centers for Disease Control and Prevention

Completed

Testing a Personally Controlled Health Record to Ameliorate Influenza at MIT (Indivo at MIT)

Influenza

United States
Denver Health and Hospital Authority

Not yet recruiting

Digital Storytelling to Reduce Pediatric Influenza Vaccination Disparities

Influenza

United States
Denver Health and Hospital Authority

Terminated

STAT-STatin and Aspirin in Trauma (STAT)

Wounds and Injuries | Venous Thromboembolism

United States
Denver Health and Hospital Authority

Active, not recruiting

Restricted or Liberal Antibiotics After Appendectomy - Denver Health (CASA RELAX)

Appendicitis

United States
Denver Health and Hospital Authority

Withdrawn

Transgender Therapeutic Support Groups

Gender Dysphoria in Adolescents and Adults

United States
Denver Health and Hospital Authority

Completed

Pupil Dilation for Treatment of IFIS

Intraoperative Floppy Iris Syndrome

United States
Denver Health and Hospital Authority

Completed

Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication

Coagulopathy | Empyema, Pleural | Parapneumonic Effusion

United States
Denver Health and Hospital Authority

Completed

Motivational Interviews for Depression in Primary Care

Major Depression

United States
Denver Health and Hospital Authority

Terminated

Dexmedetomidine (Precedex®) for Severe Alcohol Withdrawal Syndrome (AWS) and Alcohol Withdrawal Delirium (AWD)

Alcohol Withdrawal Delirium | Alcohol Withdrawal Associated Autonomic Hyperactivity | Alcohol Withdrawal Hallucinosis | Alcohol Withdrawal-Induced Delirium Tremens

United States
Denver Health and Hospital Authority

Completed

Splinting Versus Not Splinting of the Distal Lower Extremity After Intramedullary Nailing for Tibial Fractures

Tibia Fracture

United States
Denver Health and Hospital Authority

Completed

Bacterial Contamination of Workwear

Bacterial Contamination of Physician Attire

United States
Denver Health and Hospital Authority

Completed

Evaluation of Opt-Out Rapid HIV Testing in the Emergency Department

HIV Infections

United States
Denver Health and Hospital Authority

Completed

Effects of Carvedilol on Health Outcomes in Heart Failure

Heart Failure, Congestive

United States
Children's Hospital of Philadelphia
Boston Children's Hospital; Children's Hospital Medical Center, Cincinnati; University...

Completed

Comparative Effectiveness of Intravenous v. Oral Antibiotic Therapy for Serious Bacterial Infections (PIVVOT)

Pneumonia | Appendicitis | Osteomyelitis
Denver Health and Hospital Authority

Recruiting

Enhancing Cardiac Rehabilitation Through Behavioral Nudges

Coronary Artery Disease | Percutaneous Coronary Intervention | Acute Myocardial Infarction | Chronic Stable Angina | Chronic Stable Heart Failure | Valvular Disease

United States
Denver Health and Hospital Authority

Completed

Enteral Feeding in the Post-Injury Open Abdomen

Trauma to the Abdomen

United States
Denver Health and Hospital Authority

Completed

Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures

Pneumonia | Anesthesia, Local | Drug Effect | Opioid Dependence | Surgical Procedure, Unspecified | Rib Fractures | Local Infiltration | Nerve Pain | Rib Trauma | Pain; Catheter (Other) | Intercostal Rib | Chest Injury Trauma

United States
Denver Health and Hospital Authority

Terminated

Preventing Alcohol Withdrawal Syndrome With Oral Baclofen

Alcohol Withdrawal Syndrome

United States
Denver Health and Hospital Authority

Completed

Auricular Acupuncture For The Treatment Of Non-Epileptic Seizures

Convulsion, Non-Epileptic

United States
Denver Health and Hospital Authority

Withdrawn

Randomized Study Comparing Ferric Carboxymaltose to Iron Sucrose to Treat Fe Deficiency in the Surgically Critically Ill

Functional Iron Deficiency | ICU Anemia

United States
Denver Health and Hospital Authority

Completed

A Toolbox Approach to Obesity Treatment in Primary Care (Toolbox)

Obesity

United States
Denver Health and Hospital Authority

Completed

Clinical Practice Guidelines and Impact of Audit and Feedback in the Emergency Department

Shock, Septic | Community Acquired Pneumonia

Clinical Trials Sponsored by Children's Hospital and Health Center

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