Search clinical trials for: pan-NOTCH inhibitor

Total 68017 results

Merck Sharp & Dohme LLC

Completed

A Study on the Safety and Effectiveness of L-756423 Plus Indinavir in HIV-Positive Patients Who Have Previously Taken Indinavir

HIV Infections

United States
Sequus Pharmaceuticals

Completed

Randomized, Comparative Trial of DOX-SL (Stealth Liposomal Doxorubicin Hydrochloride) Versus Bleomycin and Vincristine in the Treatment of AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Hoffmann-La Roche

Completed

A Randomized, Open-Label Study of Alternative Treatment Combinations of Dideoxycytidine (HIVID; ddC) and Zidovudine (AZT) in Patients With HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Amprenavir in Patients With Protease Inhibitor-Related Complications

HIV Infections

United States
Glaxo Wellcome

Unknown

Effectiveness and Safety of Epivir/Ziagen/Zerit (3TC/ABC/d4T) Versus Epivir/Ziagen/Sustiva (3TC/ABC/EFV) Versus Epivir/Ziagen/Agenerase/Norvir (3TC/ABC/APV/RTV) in HIV Patients Who Have Never Received Treatment

HIV Infections

United States
National Center for Research Resources (NCRR)

Unknown

Effect of Pravastatin on Endothelial Dysfunction Following a Single High Fat Meal

Heart Diseases

United States
Nexstar Pharmaceuticals

Completed

A Randomized Phase III Clinical Trial of Daunoxome Versus Combination Chemotherapy With Adriamycin/Bleomycin/Vincristine (ABV) in the Treatment of HIV-Associated Kaposi's Sarcoma.

HIV Infections | Sarcoma, Kaposi

United States
Glaxo Wellcome

Completed

An Open-Label Study to Evaluate the Efficacy and Safety of Amprenavir (141W94) and Abacavir Combination Therapy in Protease Inhibitor Experienced Subjects With HIV-1 Infection Who Are Failing Their Current Antiretroviral Treatment Regimen

HIV Infections

United States
Pfizer

Completed

A Comparison of Fluconazole and Ketoconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems

HIV Infections | Candidiasis, Esophageal

United States, Canada
Aaron Diamond AIDS Research Center

Completed

Placebo-Controlled Trial of Safety and Efficacy of Thalidomide in Patients With Infections Due to Mycobacterium and/or HIV

HIV Infections | Mycobacterium Avium-Intracellulare Infection | Tuberculosis, Mycobacterium Infection

United States
National Center for Research Resources (NCRR)
Elizabeth Glaser Pediatric AIDS Foundation

Completed

The Metabolic Effects of Protease Inhibitors in HIV Infected Children

HIV Infections

United States
National Center for Research Resources (NCRR)
Murray Fellowship

Completed

Pediatric Traumatic Brain Injury: Methylphenidate Effects on Early Recovery

Brain Injuries

United States
Parexel

Completed

The Safety and Effectiveness of Retrovir Plus HIVID Combined With Either Nevirapine or Invirase in the Treatment of HIV Infection

HIV Infections

United States
Astra USA

Completed

A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
Jacobus Pharmaceutical

Completed

Dapsone 100 Mg Versus 50 as Primary Prophylaxis for Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS-Related Complex (ARC)

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Pharmacia

Completed

A Study of Thymic Humoral Factor (THF Gamma 2) in HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I Study of Heme Arginate With or Without Tin Mesoporphyrin in Patients With Acute Attacks of Porphyria

Porphyria
Janssen, LP

Completed

Evaluation of Galantamine in the Treatment of Alzheimer's Disease

Alzheimer Disease

United States
Novartis

Completed

Investigation Into Delay to Diagnosis of Alzheimer's Disease With Exelon (InDDEx)

Alzheimer Disease | Cognition Disorders

United States
Glaxo Wellcome

Completed

A Phase I Study to Evaluate the Pharmacokinetics, Safety and Antiviral Effects of Concurrent Administration of Zidovudine (AZT) and 2'3'-Dideoxyinosine (ddI) in Patients With Human Immunodeficiency Virus (HIV)

HIV Infections

United States
Sequus Pharmaceuticals

Unknown

A Comparison of DOX-SL Versus Adriamycin Plus Bleomycin Plus Vincristine in the Treatment of Severe AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Dupont Merck

Completed

A Study of Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
GlaxoSmithKline

Unknown

Comparison of Two Dosing Regimens of GW433908/Ritonavir Versus Lopinavir/Ritonavir for 48 Weeks in HIV Patients Who Have Taken Protease Inhibitors and Experienced Virological Failure

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of the Safety and Tolerance of Long-Term Therapy With Intravenous Cytovene (Ganciclovir Sodium) for Cytomegalovirus Retinitis in Persons With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Glaxo Wellcome

Completed

A Prospective Double-Blind Study of Retrovir in Early HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

A Randomized Trial to Evaluate the Safety and Efficacy of Combination Therapy With Retrovir ( AZT ) and HIVID ( ddC ) Versus Retrovir, HIVID, and Wellferon ( Interferon Alfa-n1 ) for the Treatment of HIV Infection

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

A Six-Month Safety and Antiviral Study in HIV-1 Seropositive, AZT-Experienced Patients With CD4 Counts Less Than or Equal to 50 Cells/mm3 to Evaluate MK-639 Alone Versus Zidovudine (AZT) and 3TC Versus the Combination of MK-639 With AZT/3TC

HIV Infections

United States
Boehringer Ingelheim

Completed

An Open-Label, Non-Randomized Trial to Evaluate the Tolerability and Safety of Viramune (Nevirapine) in Adult and Pediatric Patients With Progressive HIV Disease

HIV Infections

United States
Louisiana State University Health Sciences Center...

Completed

Further Evaluation of Thalidomide's Ability to Potentiate the Immune Response to HIV-Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Retrovir and Epivir Alone or in Combination With 141W94 in HIV-Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

A Comparison of 141W94 and Indinavir in HIV-Infected Patients

HIV Infections

United States
Bayer

Completed

Phase III Randomized Double-Blind Placebo Controlled Study To Evaluate the Safety and Efficacy of Betaseron in AIDS and Advanced ARC Patients Receiving a Reduced-Dose AZT Regimen

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of the Effects of Amprenavir, a Protease Inhibitor, on Carbohydrate and Fat Metabolism in HIV-Infected Patients

HIV Infections

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

An Open Parallel Study to Determine the Optimum Dosing Schedule for AS-101 in AIDS/ARC Patients

HIV Infections

United States
Gilead Sciences
Anderson Clinical Research

Unknown

A Study of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis
Glaxo Wellcome

Completed

A Study of the Safety and Effectiveness of Different Doses of 1592U89 in HIV-Infected Patients

HIV Infections

France, Germany
U.S. Bioscience

Completed

A Study of Neutrexin Plus Leucovorin in the Treatment of Pneumocystis Carinii Pneumonia (PCP)

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Gilead Sciences

Unknown

The Safety of Tenofovir Disoproxil Fumarate Taken With Other Anti-HIV Drugs to Treat HIV-Infected Patients

HIV Infections

United States
Triangle Pharmaceuticals

Unknown

Emtricitabine Given Once A Day With Other Anti-HIV Drugs in Children With HIV

HIV Infections

United States, Argentina, Mexico, Panama, Puerto Rico, South Africa
Roche Global Development

Completed

An Open Label Evaluation of the Safety and Pharmacokinetics of Ganciclovir in Children

HIV Infections | Cytomegalovirus Retinitis

United States
University of California, San Francisco

Completed

A Randomized Controlled Prophylactic Study of Clofazimine To Prevent Mycobacterium Avium Complex Infection in HIV Disease

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Pfizer

Completed

An Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Otsuka America Pharmaceutical

Completed

A Phase I Study of Three Doses of OPC-8212 (Vesnarinone) in HIV-Infected Persons With CD4+ Cell Number > 300 Cells/mm3

HIV Infections

United States
Hoffmann-La Roche

Completed

A Randomized, Parallel Arm, Comparative, Open Label, Multicenter Study of the Activity and Safety of Two Formulations of Saquinavir in Combination With Other Antiretroviral Drugs

HIV Infections

Canada, United States
Gilead Sciences

Unknown

Safety and Effectiveness of Adding Adefovir Dipivoxil and Nelfinavir to the Anti-HIV Therapy of HIV-Infected Children

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Ganciclovir in the Treatment of Cytomegalovirus of the Large Intestine in Patients With AIDS

HIV Infections | Colitis

United States
Astra USA

Unknown

A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir

HIV Infections | Cytomegalovirus Retinitis

United States
Boehringer Ingelheim

Completed

The Safety and Effectiveness of Nevirapine and Zidovudine, Given Separately and Together, in HIV-1 Infected Patients Who Have No Symptoms of the Disease

HIV Infections

United States
Rockefeller University

Completed

A Study of Thalidomide in HIV-Infected Patients Who Are Receiving HAART

HIV Infections

United States
Pharmacia and Upjohn

Completed

A Study of Two Anti-HIV Drug Combinations in HIV-Infected Patients

HIV Infections

United States

3

Subscribe