Clinical Trials Sponsored by VertiFlex, Incorporated

Total 1174 results

Vertex Pharmaceuticals Incorporated

Completed

A Phase 1 Study to Examine the Drug-Drug Interaction of Ciprofloxacin, Itraconazole, and Rifampin on the Combination of Lumacaftor With Ivacaftor in Healthy Adult Subjects

Cystic Fibrosis

United States
Bausch & Lomb Incorporated

Completed

Tear Fluid Levels of Loteprednol Etabonate Ophthalmic Gel 0.5% Following a Single Instillation

Pharmacokinetics

United States
Bausch & Lomb Incorporated

Withdrawn

A Study to Evaluate the Performance and Safety of Artelac Rebalance® Versus Vismed in the Management of Dry Eye

Dry Eye
Cook Group Incorporated

Terminated

Cook Iliac Branch Graft Post-market Registry

Aortic Aneurysm | Iliac Aneurysm

Spain
Bausch & Lomb Incorporated

Completed

Safety and Effectiveness of the Akreos Toric Intraocular Lens.

Cataract | Astigmatism

Sweden
Bausch & Lomb Incorporated

Completed

Evaluation of Vitrase as an Adjuvant to Increase Absorption and Dispersion of Other Injected Anesthetics

Pain

United States
Bausch & Lomb Incorporated

Completed

Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase)

Drug Hypersensitivity

United States
Bausch & Lomb Incorporated

Completed

Assessment of Intravitreous Injections of Vitrase for Inducing Posterior Vitreous Detachment

Diabetic Retinopathy | Vitreous Detachment

United States
Bausch & Lomb Incorporated

Completed

A Bioequivalence Study of Tobramycin and Prednisolone Acetate Compared to PredForte

Postoperative Complications | Eye Infections

United States
Bausch & Lomb Incorporated

Completed

Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage

Diabetic Retinopathy | Vitreous Hemorrhage

Spain, Australia, United Kingdom, Brazil, Hungary, Italy, Netherlands, Poland, South Africa
Bausch & Lomb Incorporated

Completed

Evaluation of Vitrase as a Spreading Agent

Pain

United States
Bausch & Lomb Incorporated

Completed

Safety Study for Bepotastine Besilate Ophthalmic Solution in Normal Volunteers

Allergic Conjunctivitis
Bausch & Lomb Incorporated

Completed

Efficacy and Safety of Bromfenac Ophthalmic Solution

Cataract Surgery

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study to Assess the Relative Bioavailability Three New Formulations of Telaprevir in Healthy Subjects

Chronic Hepatitis C

United States
Bausch & Lomb Incorporated

Completed

Alrex® Versus Patanol in the Treatment of Seasonal Allergic Conjunctivitis(SAC)

Seasonal Allergic Conjunctivitis

Singapore
Bausch & Lomb Incorporated

Completed

Loteprednol and Tobramycin Versus Tobramycin and Dexamethasone, in the Treatment of Blepharokeratoconjunctivitis

Conjunctivitis | Keratitis | Blepharitis

Singapore
Cook Group Incorporated

Completed

V-Flex Plus PTX Drug Eluting Coronary Stent (ELUTES III)

Coronary Artery Disease

United States
Vertex Pharmaceuticals Incorporated

Completed

Drug-Drug Interaction Study of VX-770 and VX-809 in Healthy Subjects

Cystic Fibrosis

United States
Bausch & Lomb Incorporated

Completed

Evaluation of Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery

Pain | Inflammation

United States
Bausch & Lomb Incorporated

Completed

Systemic Pharmacokinetics of BOL-303224-A

Conjunctivitis, Bacterial

United States
Bausch & Lomb Incorporated

Terminated

Safety and Efficacy of Fluocinolone Acetonide Intravitreal Implant

Non-infectious Uveitis
Bausch & Lomb Incorporated

Completed

Ocular Tolerance and Intraocular Pressure (IOP) Effects of Zylet Versus Tobradex

Inflammation
Bausch & Lomb Incorporated

Completed

Safety and Efficacy of Intravitreal Fluocinolone Acetonide Implants in Patients With Diabetic Macular Edema

Diabetic Macular Edema

China, India
Bausch & Lomb Incorporated

Completed

Loteprednol Etabonate Opthalmic Suspension for the Treatment of Dry Eye

Dry Eye

United States
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-770 and Rifampin in Healthy Male Subjects

Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Completed

Drug-Drug Interaction Study of VX-809 and VX-770 in Healthy Subjects

Cystic Fibrosis

Netherlands
Vertex Pharmaceuticals Incorporated

Completed

Merimepodib (MMPD) in Triple Combination for the Treatment of Chronic Hepatitis C

Hepatitis | Hepatitis C

United States
Vertex Pharmaceuticals Incorporated

Completed

Phase 2 Clinical Study in Rheumatoid Arthritis With an Investigational Oral p38 MAP Kinase Inhibitor VX-702

Rheumatoid Arthritis

Poland, Croatia, Russian Federation, Bulgaria, Czech Republic, Former Serbia and Montenegro, Slovakia, Slovenia, Ukraine
Vertex Pharmaceuticals Incorporated

Completed

A Study in Rheumatoid Arthritis With an Investigational Oral p38 MAP Kinase Inhibitor VX-702

Rheumatoid Arthritis

Bulgaria, Croatia, Former Serbia and Montenegro, Poland, Russian Federation, Slovenia
Cook Group Incorporated
Cook Ireland, Ltd.; Cook Biotech Incorporated

Completed

A Randomized Clinical Trial Comparing Surgisis AFP to Advancement Flap for the Repair of Anal Fistulas (Surgisis® AFP)

Anal Fistula

Germany
Celularity Incorporated
Celgene Corporation

Terminated

Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Celularity Incorporated
Celgene Corporation

Completed

A Multi-Center Study to Evaluate the Safety and Efficacy of Intravenous Infusion of Human Placenta-Derived Cells (PDA001) for the Treatment of Adults With Moderate-to-Severe Crohn's Disease

Crohn's Disease

United States
Hollister Incorporated
Loyola University

Completed

Preliminary Study of Peel Force and Discomfort of Removal of Adhesive Barriers in Normal and Peristomal Skin

Dermatologic Complications

United States
Bastyr University
Gencare Incorporated

Completed

Effects of Qigong, Tai Chi and Yoga Practice in Older Adults

Healthy

United States
GlycoMimetics Incorporated
Quotient Sciences

Completed

A Study in Healthy Volunteers to Investigate How Much Test Medicine [14C]-Uproleselan is Taken up by the Body When Administered Directly Into the Vein (IV)

Healthy Subjects

United Kingdom
Celularity Incorporated
Celgene Corporation

Terminated

Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Ischemic Stroke

Stroke, Acute | Middle Cerebral Artery Stroke | Posterior Cerebral Artery Stroke

United States
Designed Altobaric Technology, Incorporated

Withdrawn

Effect of Repeated Exposures to Compressed Air on Patients With AIDS (DANET1)

AIDS

United States
Loyola University
Genta Incorporated

Withdrawn

Rituximab, Ifosfamide, Carboplatin, and Etoposide (RICE) Followed by Gallium Nitrate, Rituximab and Dexamethasone (GARD) for Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Diffuse Large B-cell Lymphoma

United States
Anergis
Inflamax Research Incorporated

Completed

Compare Dose Regimens of AllerT, in Adults With Allergic Rhino-Conjunctivitis to Birch Pollen Studied in EEC

Allergic Rhino-Conjunctivitis

Canada
Purdue University
Ingredion Incorporated

Completed

Effects of Resistant Starch in a Beverage on Post-prandial Glycemic and Insulinemic Responses

Hyperglycemia, Diabetes, and Obesity

United States
Accuray Incorporated
Stanford University

Withdrawn

Transarterial Chemoembolization (TACE) vs. CyberKnife for Recurrent Hepatocellular Carcinoma (HCC)

Recurrent Hepatocellular Carcinoma

United States
Infrared Cameras Incorporate

Completed

A Study to Validate Comparability of an Infrared Thermographic Camera Versus Oral, Forehead, and Ear Thermometers When Determining Body Temperature in Adult Participants

Temperature Change, Body

United States
William Cook Europe
Cook Group Incorporated; MED Institute, Incorporated; William Cook Australia

Completed

Clinical Study to Assess Safety and Effectiveness of the Zenith® Dissection Endovascular System in Patients With Aortic Dissection

Aortic Dissection Involving the Descending Thoracic Aorta

Italy, Germany, Australia, Czech Republic, France
Cook Group Incorporated
William Cook Europe; MED Institute, Incorporated; William Cook Australia

Completed

STARZ-TX2 Clinical Study: Study of Thoracic Aortic Aneurysm Repair With the Zenith TX2 Endovascular Graft (STARZ-TX2)

Thoracic Aortic Aneurysm

United States, Italy, Canada
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Recruiting

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD)

Sickle Cell Disease | Hemoglobinopathies | Hematological Diseases | Hydroxyurea Failure | Hydroxyurea Intolerance

United States, Italy, United Kingdom, Germany
Hollister Incorporated
Parexel; Technomics Research

Recruiting

Continence Care Registry (ConCaRe™)

Neurogenic Bladder | Non-Neurogenic Bladder

United States
Laboratoire Chauvin
Bausch & Lomb Incorporated

Completed

A Study to Evaluate the Performance and Safety of CBL-101 Versus Vismed® Multi Eye Drops in the Management of Dry Eye

Dry Eye

France, Belgium
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease

Sickle Cell Disease | Hemoglobinopathies | Hematological Diseases

United States, Belgium, Canada, France, Germany, Italy, United Kingdom
Bausch & Lomb Incorporated
ORA, Inc.

Completed

A Single-Center Evaluation of the Relative Efficacy of EM-100 Compared to Zaditor® (Ketotifen Fumarate Ophthalmic Solution 0.035%) and Vehicle

Allergic Conjunctivitis

United States
Encore Medical, L.P.
DJO Incorporated

Completed

Reverse Shoulder Prosthesis Prospective Multi-Center Study

Shoulder Arthropathy | Rotator Cuff Deficiency | Failed Shoulder Replacement

United States

Clinical Trials Sponsored by VertiFlex, Incorporated

Sponsors and Collaborators

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Drug Interventions

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CROs in New Zealand

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