Clinical Trials Sponsored by Agenus Inc.

Total 37570 results

BRIM Biotechnology Inc.
ORA, Inc.

Completed

Safety and Efficacy of BRM421 for Dry Eye Syndrome Treatment

Dry Eye Syndrome

United States
Eisai Korea Inc.

Completed

A Study of Fycompa (Perampanel) in Korean Participants

Epilepsy

Korea, Republic of
ImmunoVaccine Technologies, Inc. (IMV Inc.)

Terminated

A Study of DPX-Survivac Vaccine Therapy in Patients With Recurrent Survivin-expressing DLBCL

Diffuse Large B-Cell Lymphoma

Canada
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

A Phase 3 Study of Brentuximab Vedotin (SGN-35) in Patients at High Risk of Residual Hodgkin Lymphoma Following Stem Cell Transplant (The AETHERA Trial)

Disease, Hodgkin

United States, United Kingdom, France, Romania, Poland, Italy, Bulgaria, Hungary, Russian Federation, Czechia, Spain, Germany, Serbia
Eisai Inc.
PharmaBio Development Inc.

Completed

E7050 in Combination With Sorafenib Versus Sorafenib Alone as First Line Therapy in Participants With Hepatocellular Carcinoma

Hepatocellular Carcinoma

Belgium, Italy, Spain, United States, Ukraine, United Kingdom
LifeSeasons Inc.
KGK Science Inc.

Completed

Investigating the Efficacy of Rest-ZZZ Formula in Healthy Participants With Difficulty Falling Asleep or Staying a Sleep

Healthy | Sleep

Canada
SerenaGroup, Inc.
LifeCuff Technologies Inc.

Withdrawn

Evaluating Remote Ischemic Conditioning (RIC) and Standard of Care vs. Sham Therapy and Standard Care

Diabetic Foot Ulcer
Eisai Korea Inc.

Completed

Study in Patients With Moderated to Severe Rheumatoid Arthritis Who Have Failed to Combination Therapy of Conventional Disease-modifying Antirheumatic Drugs (cDMARDs) to cDMARD Plus ANti-TNF Versus cDMARDs in Real World (HUMAN)

Arthritis, Rheumatoid

Korea, Republic of
NeuroActiva, Inc.
Biomed Industries, Inc.

Unknown

A Phase 3 Randomized Double Blind Efficacy and Safety Study of Oral Polio Vaccine and NA-831 for Covid-19 (OPV-NA831)

Covid19 | SARS-CoV-2 | SARS-CoV Infection | SARS (Severe Acute Respiratory Syndrome)

New Zealand, United States
Naked Biome, Inc.
Therapeutics, Inc.

Completed

A Study of the Safety, Engraftment, and Action of Multi-Dosed NB01 in Adults With Moderate Acne

Acne Vulgaris

United States
EndoCeutics Inc.
AMAG Pharmaceuticals, Inc.

Withdrawn

Effect of Intravaginal Prasterone on Symptoms of VVA in Women Under Treatment With an Aromatase Inhibitor for Breast Cancer

Vaginal Atrophy in Breast Cancer Patients
AIDP, Inc.
KGK Science Inc.

Completed

Evaluating Efficacy of Investigational Products on Spontaneous Bowel Movements in Healthy People With ≤ 3 Complete Weekly Spontaneous Bowel Movements

Healthy | Functional Constipation

Canada
AVEO Pharmaceuticals, Inc.
Biodesix, Inc.

Withdrawn

A Study of Ficlatuzumab With HiDAC and HiDAC Alone in Adults With Relapsed or Refractory Acute Myeloid Leukemia (CyFi2)

Acute Myeloid Leukemia
Eisai Korea Inc.

Completed

Study to Observe the Change in Microbiome in Human Derived Sample and the Relation With Clinical Response Before and After the Anti-TNF Treatment in IBD Patients (ETERNITY)

Inflammatory Bowel Disease

Korea, Republic of
Actavis Inc.
Watson Laboratories, Inc.

Completed

A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment of Bacterial Vaginosis in Non-pregnant Women

BACTERIAL VAGINOSIS | Signs and Symptoms to be Evaluated and Recorded Include | Vaginal Discharge Color, Odor, and Consistency | Vulvovaginal Itching and Irritation (Subjective) Absent, Mild, Moderate, or Severe | Vulvovaginal Inflammation (Objective) Absent, Mild, Moderate, or Severe

United States, Dominican Republic, Puerto Rico
Actavis Inc.
Watson Laboratories, Inc.

Completed

Randomized, Double-blind, Multiple-site, Placebo-controlled, Parallel-design Study in Patients With Moderate to Severe Facial Erythema Associated With Rosacea

Rosacea

United States
Athenex, Inc.
TKL Research, Inc.

Completed

Single-Center Study Evaluating Systemic Exposure and Safety of KX2-391 Ointment 1% on the Face or Balding Scalp in Subjects With Actinic Keratosis

Actinic Keratoses

United States
HyGIeaCare, Inc.
Biostatistical Consulting, Inc.

Withdrawn

HyGIeaCare Procedure for Chronic Constipation

Constipation - Functional

United States
Esperion Therapeutics, Inc.
Medpace, Inc.

Completed

Evaluation of ETC-1002 vs Placebo in Patients Receiving Ongoing Statin Therapy

Hypercholesterolemia

United States
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects

Solid Tumors

United States
Daiichi Sankyo, Inc.
Quintiles, Inc.

Completed

Comparison of Two Doses of Edoxaban Using Different Tests (Assays) and Clinical Outcomes

Atrial Fibrillation

Denmark, Hungary, Croatia, Serbia, Spain, Russian Federation, Bulgaria, Latvia, Czechia, Poland, Estonia, Belgium, Lithuania, Slovakia, Ukraine
Cascadian Therapeutics Inc.

Completed

Phase I Trial of PX-478

Lymphoma | Advanced Solid Tumors

United States
Cascadian Therapeutics Inc.

Completed

A Trial of PX-12 in Patients With a Histologically or Cytologically Confirmed Diagnosis of Advanced or Metastatic Cancer

Metastatic Cancer | Advanced Cancer

United States
Cascadian Therapeutics Inc.

Completed

Phase 1 and 2 Study of PX-866 and Cetuximab

Incurable Metastatic Colorectal Carcinoma | Incurable Progressive, Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

United States, Canada
Cascadian Therapeutics Inc.

Terminated

Study of PX-866 and Vemurafenib in Patients With Advanced Melanoma

Advanced BRAF-mutant Cancers

United States
Ocular Therapeutix, Inc.
ORA, Inc.

Completed

OTX-14-007: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis

Chronic Allergic Conjunctivitis
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

A Pivotal Open-Label Trial of Brentuximab Vedotin for Hodgkin Lymphoma

Disease, Hodgkin

United States, France, Canada, Belgium, Italy
Eisai Korea Inc.

Completed

A Plan on Investigation and Collection of Aricept Safety Information With a Dose Increase on Alzheimer's Disease Patients (AID)

Alzheimer's Disease

Korea, Republic of
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

A Brentuximab Vedotin Trial for Patients Who Have Previously Participated in a Brentuximab Vedotin Study

Lymphoma, Non-Hodgkin | Lymphoma, Large-Cell, Anaplastic | Disease, Hodgkin

United States, France
Eisai Korea Inc.

Completed

Eribulin Mesylate Phase IV Clinical Trial in Korean Patients With Metastatic or Locally Advanced Breast Cancer (ESKIMO)

Breast Cancer | Breast Neoplasms

Korea, Republic of
KGK Science Inc.
Lonza Inc.

Completed

A Pilot Clinical Trial on the Efficacy of Two Carnitine-Based Products on Muscle Function in Healthy Older Adults (15CAHL)

Muscle Function

Canada
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

A Phase 1 Study of Brentuximab Vedotin Combined With Multi-Agent Chemotherapy for Hodgkin Lymphoma

Disease, Hodgkin

United States, Canada
FORUM Pharmaceuticals Inc
Quintiles, Inc.

Completed

Phase 1 Study to Assess the Effects of EVP-6124 on the QT/QTc Interval in Healthy Subjects (TQT)

Healthy Subjects | Cardiac Repolarization
Neurovance, Inc.

Completed

A Study to Evaluate the Abuse Potential of EB-1020 Immediate-Release in Healthy Recreational Stimulant Users

Healthy Volunteers | Drug Users

United States
Neurovance, Inc.

Completed

A Study to Evaluate the Safety, Tolerance, and Pharmacokinetic and Pharmacodynamic Profile Of 1 SR Formulation of EB-1020

Normal, Healthy Volunteers

Australia
Savara Inc.
INC Research Limited

Completed

Inhaled Vancomycin Tolerability, Safety and Pharmacokinetics

Healthy | Cystic Fibrosis

Australia
Eisai Korea Inc.

Terminated

Correlation Between Regional Brain Volume and Response to Donepezil Treatment in AD Patients

Alzheimer's Disease

Korea, Republic of
Mati Therapeutics Inc.
QLT Inc.

Completed

A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)

Ocular Hypertension | Open-Angle Glaucoma

United States
Eisai Korea Inc.

Completed

Low and High Dose Zonisamide in Children as Monotherapy

Epilepsy

Korea, Republic of
Labopharm Inc.
Algorithme Pharma Inc

Completed

Comparative Bioavailability Study of Extended-release and Immediate-release Trazodone in Healthy Adult Volunteers

Healthy

Canada
Eisai China Inc.

Completed

Efficacy and Safety of Cinitapride Tablets in the Treatment of Mild to Moderate Functional Dyspepsia

Dyspepsia

China
Hygieia, Inc
TKL Research, Inc.

Completed

Efficacy and Safety of Frequently Modified Intensive Insulin

Diabetes

United States
Astellas Pharma China, Inc.
Seagen Inc.

Active, not recruiting

A Study to Evaluate Enfortumab Vedotin (ASG-22CE) in Chinese Participants With Locally Advanced or Metastatic Urothelial Cancer Who Previously Received Platinum-containing Chemotherapy and Programmed Cell Death Protein-1 ( PD 1) / (Programmed Death Ligand-1 (PD-L1) Inhibitor Therapy

Metastatic Urothelial Cancer

China
Arisan Therapeutics, Inc.
United States Department of Defense; Battelle Memorial Institute; The Defense...

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Oral ARN-75039 in Healthy Adult Subjects

Lassa Virus Infection

United States
Asan Medical Center
Seoul Business Agency

Recruiting

The Expected Advantage of Administering Prophylactic Antibiotics Using Target- Concentration Controlled Infusion

Pharmacokinetics | General Surgery | Anti-bacterial Agents

Korea, Republic of
University of Southampton
European Space Agency

Active, not recruiting

Monitoring Antioxidant/Redox Status at Concordia (MARS-C) (MARS-C)

Oxidative Stress

United Kingdom
International Agency for Research on Cancer

Active, not recruiting

Cervical Cancer Screening With Human Papillomavirus Testing (ESTAMPA)

Cervical Cancer | CIN2 | CIN3

Peru, Colombia, Argentina, Bolivia, Costa Rica, Honduras, Mexico, Paraguay, Uruguay
Mahidol University
International Atomic Energy Agency

Completed

Body Composition in Preschool Children

Obesity | Wasting

Thailand
International Agency for Research on Cancer

Enrolling by invitation

Can an Educational Intervention Targeting General Practitioners Increase HPV Vaccination Coverage in AuRA_Lyon (France) (PAPRICA)

Human Papillomavirus Vaccination

France
Institut Pasteur
National Research Agency, France

Completed

Milieu Intérieur Collection - Genetic & Environmental Determinants Of Immune Phenotype Variance (MI)

Healthy Subjects | Individuality

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