Search clinical trials for: sepsis biomarkers

Total 9060 results

Radboud University Medical Center

Completed

Effect of Selective iNOS Inhibition During Human Endotoxemia

Endotoxemia

Netherlands
Radboud University Medical Center

Completed

Pathophysiology and Clinical Relevance of Endotoxin Tolerance in Humans

Endotoxemia

Netherlands
Hamilton Health Sciences Corporation

Unknown

UGIST: Ultrasound Guided Internal Jugular Short-Term Central Venous Catheters Tunneling (UGIST)

Bacteremia | Infection

Canada
Tropical Medicine Research Institute
London School of Hygiene and Tropical Medicine; International Atomic Energy...

Completed

Antimalarial Treatments for Clearing Low Density P. Falciparum and Its Impact on Malaria Transmission

Plasmodium Falciparum | Asymptomatic Parataemia | Sub Patent Parasitaemia

Sudan
University of Zurich

Unknown

Acute Phase Proteins as Early Markers in Sepsis

Sepsis

Switzerland
University of Zurich

Unknown

Are the Pancreatic Serum Proteins Pancreatic Stone Protein (PSP) and Pancreatitis-Associated Protein (PAP) Predictive for the Development of Sepsis? Retrospective Study in Trauma Patients With Soft Tissue Defects.

Trauma Patients With Soft Tissue Defects

Switzerland
Christiana Care Health Services

Terminated

Enteral Glutamine in Critical Illness

Sepsis | Critical Illness | Respiratory Insufficiency

United States
Biosynexus Incorporated
GlaxoSmithKline

Completed

Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity Study in VLBW Neonates of BSYX-A110 (N003)

Staphylococcal Sepsis

United States
Biosynexus Incorporated
GlaxoSmithKline

Completed

Safety and Pharmacokinetics Study in VLBW Neonates With BSYX-A110 (N002)

Neonatal Staphylococcal Sepsis

United States
Ash Access Technology

Unknown

A Multi-Centered, Two-Arm, Randomized Study Comparing the Effects of AAT-023 (Zuragen) Solution, and Heparin on the Incidence of Catheter Related Blood Stream Infections in Tunneled Chronic Central Venous Catheters for Dialysis

End Stage Renal Disease

United States
National Cancer Institute (NCI)

Completed

Anidulafungin Versus Fluconazole in the Treatment of Candidemia

Candidiasis | Candida

United States
National Cancer Institute (NCI)

Completed

Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients

Mycoses | Candidiasis | Fungemia | Aspergillosis

United States
National Cancer Institute (NCI)

Completed

A Pilot Trial of Tamoxifen and 4-HPR (4-N-Hydroxyphenyl Retinamide) in Persons at High Risk for Developing Breast Cancer

Breast Cancer | Breast Neoplasms

United States
National Cancer Institute (NCI)

Completed

Phase I-II Multiple-Dose Safety and Efficacy Study of a Selective Inhibitor of Cyclooxygenase - 2 (SC-58635) in Hereditary Non-Polyposis Colorectal Cancer (HNPCC) Patients and Carriers

Colorectal Neoplasm | Hereditary Nonpolyposis

United States
National Cancer Institute (NCI)

Completed

A Phase I Trial of Tamoxifen and 9-Cis-Retinoic Acid in Breast Cancer Patients

Breast Cancer | Breast Neoplasm

United States
National Cancer Institute (NCI)

Completed

An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections

Mycoses | Candidiasis | Fungemia | Aspergillosis

United States
National Cancer Institute (NCI)

Completed

A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer

Sepsis | Hematologic Diseases | Breast Neoplasms | Neutropenia | Fever

United States
University of Roma La Sapienza

Completed

Continuous Infusion of Terlipressin in Septic Shock

Septic Shock

Italy
Bnai Zion Medical Center

Completed

Lactulose Supplementation in Premature Infants

Sepsis | Necrotizing Enterocolitis

Israel
Javeriana University
Asociacion Colombiana de Infectologia, ACIN. Infectious Diseases Society... and other collaborators

Completed

Efficacy of Cefepime Continuous Infusion Versus an Intermittent Dosing Regimen (CEFPK/PD)

Sepsis | Bacteremia

Colombia
Mayo Clinic
Allina Health System

Completed

A Simple Clinical Tool to Help Assess Patient Volume (Fluid) Status

Sepsis

United States
Onze Lieve Vrouwe Gasthuis

Unknown

Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsis

Severe Sepsis | Microcirculation

Netherlands
Universidad de Antioquia
Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnología (COLCIENCIAS)

Completed

Unfractioned Heparin for Treatment of Sepsis

Sepsis | Bacterial Infections

Colombia
University of Washington
National Institutes of Health (NIH)

Completed

Effect of Leukoreduced Blood Transfusions on Infection Following Trauma

Wounds and Injuries

United States
Astellas Pharma Inc
Astellas Pharma Taiwan, Inc.

Completed

Micafungin Versus Fluconazole in the Treatment of Invasive Candidiasis and Candidemia

Candidemia | Invasive Candidiasis

Taiwan
University of Pittsburgh
Elan Pharmaceuticals

Completed

Pharmacodynamic Parameters of Two Different Doses of Cefepime

Pneumonia | Bacteremia | Infection

United States
Medical University of Vienna

Completed

Oxytocin Effects on Cytokines and Endocrine Parameters After LPS Induced Systemic Inflammatory Effects in Healthy Volunteers

Sepsis

Austria
Eli Lilly and Company

Completed

A Safety Evaluation of Drotrecogin Alfa (Activated) in Patients With Blood Cancer, Severe Infection Related to Bone Marrow Transplantation

Sepsis | Hematologic Neoplasms | Infection | Hematopoietic Stem Cell Transplantation

United States
Eli Lilly and Company

Completed

The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death

Sepsis

Canada, Finland, Belgium, Argentina, Chile, Australia, Austria, Brazil, Czech Republic, Denmark, Egypt, France
Eli Lilly and Company

Completed

An Open Label Study of Severe Sepsis in Adults

Severe Sepsis

Belgium
Eli Lilly and Company

Completed

Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis

Sepsis

United States, United Kingdom, France, Slovakia, Switzerland, Australia, Poland, Italy, Chile, Germany, Mexico
Beth Israel Medical Center

Terminated

The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study

Pneumonia | Cystitis | Bacteremia | Surgical Wound Infection | Enterocolitis, Pseudomembranous

United States
London School of Hygiene and Tropical Medicine
World Health Organization; Tropical Medicine Research Institute

Completed

Randomized Trial of Two Antimalarial Treatments for Clearing Low Density P.Falciparum Parasitaemia in Sudan

Plasmodium Infections

Sudan
Washington University School of Medicine

Completed

Trial Evaluating the Efficacy of a Chlorhexidine-Impregnated Sponge (BIOPATCH®) to Reduce Catheter-Related Bloodstream Infections in Hemodialysis Patients

Catheter Related Bloodstream Infection

United States
National Taiwan University Hospital

Unknown

Images in Extracranial Artery Stenosis

Extracranial Atherosclerosis

Taiwan
University of Helsinki

Completed

Combination Therapy With Fluoroquinolone in Staphylococcus Aureus Bacteremia (FINLEVO)

Sepsis | Bacteremia | Staphylococcus Aureus | Endocarditis

Finland
Eli Lilly and Company

Completed

Extended Therapy of Drotrecogin Alfa (Activated) 4 vs 7 Days Infusion

Sepsis | Hypotension

France, United States
Inverness Medical Innovations

Completed

The Utility of Ischemia Modified Albumin (IMA) in Sepsis

Sepsis | Systemic Inflammatory Response Syndrome | Severe Sepsis | Sepsis Syndrome

United States
Centers for Disease Control and Prevention
United States Agency for International Development (USAID); Bill and Melinda... and other collaborators

Unknown

Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn

Sepsis | Infant, Newborn, Diseases | Puerperal Infection

South Africa
Medical University of Vienna

Unknown

Simvastatin in Patients With Septic Shock

Septic Shock

Austria
Charite University, Berlin, Germany

Completed

IL 6 Measurement Using a New Densitometric Bedside (POC) Test

Sepsis, Septic Shock

Germany
University Hospital Freiburg
University Hospital, Basel, Switzerland

Completed

Prevention of Catheter-Associated Infection With the Skin Disinfectant Octenidine Dihydrochloride

Bacterial Infections | Bacteremia | Catheter-Associated Infections | Catheterization, Central Venous

Germany, Switzerland
Hunter Holmes Mcguire Veteran Affairs Medical Center
Centers for Disease Control and Prevention; Sage Products, Inc.

Unknown

Multicenter Trial of Daily Chlorhexidine Bathing to Reduce Nosocomial Infections (CBET)

MRSA Infection | MRSA Colonization | VRE Infection | VRE Colonization | Nosocomial Bacteremia

United States
Fraunhofer-Institute of Toxicology and Experimental...

Completed

A Pilot Monocenter Study to Assess Cellular and Soluble Biomarkers in Nasal Secretions

Healthy Subjects | Seasonal Allergic Rhinitis

Germany
Nordic Bioscience A/S
Novartis

Completed

SMC021A - Absorption, Efficacy and Tolerance in Patients With Osteoarthritis. A Placebo-Controlled 14-Days Study

Osteoarthritis

Denmark
Nordic Bioscience A/S
Novartis

Completed

Pharmacokinetics/Pharmacodynamics of Oral Salmon Calcitonin in Patients With Osteoarthritis

Osteoarthritis

Denmark
Medical University of Graz

Completed

Investigation of Correlation Between Interstitial and Arterial Blood Glucose Concentrations in Septic Patients

Severe Sepsis

Austria
University of Roma La Sapienza

Completed

Phenylephrine Versus Norepinephrine in Septic Shock

Septic Shock

Italy
Tampere University

Completed

Casodex/Zoladex Biomarkers in Localised Prostate Cancer

Prostate Cancer

Finland
Herzog Hospital

Terminated

Prevention of Bacteremia Induced by Debridement of Pressure Ulcer

Bacteremia | Pressure Ulcers

Israel

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