Clinical Trials Sponsored by National Cancer Centre, Singapore

Total 15462 results

National Cancer Centre, Singapore
Novartis

Terminated

Study of TKI 258 in Combination With Xeloda and Oxaliplatin in Advanced Colorectal and Gastric Cancer

Gastric Cancer | Colorectal Cancer

Singapore
National Cancer Centre, Singapore
Novartis

Completed

A Trial of Gefitinib in Combination With BKM120 in Patients With Advanced Non-Small Cell Lung Cancer, With Enrichment for Patients Whose Tumours Harbour Molecular Alterations of PI3K Pathway and Known to Overexpress EGFR (BKM120)

Non-Small Cell Lung Cancer | Solid Tumors

Singapore
National Cancer Centre, Singapore
Novartis

Unknown

Safety and Tolerability Study of RAD001 and LBH589 in All Solid Tumors With Enrichment for EBV Driven Tumors

Nasopharyngeal Carcinoma, Lymphomas, Any EBV+ Solid Tumour

Singapore
National Cancer Centre, Singapore
Perspectum

Completed

LiverMultiScan Analysis of MRI Scans in HCC

Hepatocellular Carcinoma

Singapore
National Cancer Centre, Singapore
Pfizer

Active, not recruiting

Phase 2 Study of Dacomitinib in NSCLC

NSCLC Stage IV | NSCLC Stage IIIB | Recurrent NSCLC | NSCLC Stage IIIC | EGFR Positive Non-Small Cell Lung Cancer

Korea, Republic of, Hong Kong, Thailand, Singapore, Malaysia
National Cancer Centre, Singapore
GlaxoSmithKline

Completed

Study of Ofatumomab in Combination With ICE-chemotherapy in Patients With Diffuse Large B-cell Lymphoma (DLBCL) (DLBL)

Diffuse Large B-cell Lymphoma

Singapore
National Cancer Centre, Singapore
Singapore Clinical Research Institute

Completed

Prospective Cohort Study on the Clinical Trajectory of Resected Hepatocellular Carcinoma (PLANET)

Hepatocellular Carcinoma

Singapore, Malaysia, Philippines, Thailand
National Cancer Centre, Singapore
Singapore General Hospital; Singapore Cancer Society; Genome Institute of Singapore and other collaborators

Recruiting

Breast Cancer Exercise Intervention Study (BREXINT)

Locally Advanced Breast Cancer | Early-stage Breast Cancer

Singapore
National Cancer Centre, Singapore
Ministry of Health, Singapore

Completed

Novel Palliative Care Model for Advanced Cancer Patients: A Randomized Controlled Trial Study (SPARKLE2)

Cancer

Singapore
National University, Singapore
National Cancer Centre, Singapore; Singapore Thong Chai Medical Institute

Unknown

Health-related Quality of Life-intervention in Survivors of Breast and Other Cancers Experiencing Cancer-related Fatigue Using Traditional Chinese Medicine: The HERBAL Trial (HERBAL)

Cancer | Fatigue | Cognitive Impairment

Singapore
National Cancer Centre, Singapore
National Cancer Centre Research Fund

Recruiting

Somatostatin Receptor Imaging in NPC, EBV Related Cancers

Nasopharyngeal Cancer | Epstein-Barr Virus Related Carcinoma

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

Metronomic Capecitabine, Oxaliplatin and UGT1A1 Genotype-directed Irinotecan in Metastatic Pancreatic Cancer Patients

Metastatic Pancreatic Cancer

Singapore
National Cancer Centre, Singapore
SingHealth Polyclinics; National University of Singapore

Completed

Impact of a Breast cAncer Survivorship Interprofessional Community Care Model (BASIC)

Breast Cancer | Survivorship

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Completed

Impact of Measures Taken to Contain COVID-19 on Hospital Surgical Care Services and Clinical Outcomes

Surgery

Singapore
National Heart Centre Singapore
Singapore National Eye Centre

Unknown

REWARD: Using the REtina as a Window To Detect Cardiac microvasculAR Dysfunction In Diabetes Mellitus

Microalbuminuria | Diastolic Dysfunction | Retinopathy, Diabetic

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

The Role of Bexarotene in Inducing Susceptibility to Chemotherapy in Metastatic TNBC

Metastatic Triple-Negative Breast Carcinoma

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Completed

OXIRI [Oxaliplatin (O), Xeloda (X) and Irinotecan (I)] in Pancreatic Adenocarcinoma (OXIRI)

Pancreatic Cancer

Singapore
National University Hospital, Singapore
Yonsei University; National Cancer Centre, Singapore

Unknown

A Study of Genomic-guided 'Standard-of-care' Chemotherapy for in Advanced Gastric Cancer Patients (3G)

Recurrent Gastric Cancer

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Active, not recruiting

Dose-determining and Dose-confirmatory Study to Investigate the Optimal Dose of Tamoxifen in Breast Cancer Patients According to Genotype Status of TCF20 rs932376

Breast Cancer

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore; National University of...

Unknown

Clinical Validation of a Microfluidic Device for Isolation and Molecular Characterization of Circulating Tumor Cells (CTC)

Cancer

Singapore
National Cancer Centre, Singapore

Unknown

Vaccine Therapy and Celecoxib in Treating Patients With Metastatic Nasopharyngeal Cancer

Head and Neck Cancer

Singapore
National Cancer Centre, Singapore

Unknown

Combination Chemotherapy and Interferon Alfa-2b in Treating Patients With Nonmetastatic Liver Cancer That Cannot Be Removed by Surgery

Liver Cancer

Singapore
National Cancer Centre, Singapore

Unknown

Gemcitabine and Carboplatin Followed By Laboratory-Treated T Lymphocytes in Treating Patients With Metastatic or Locally Recurrent Epstein-Barr Virus-Positive Nasopharyngeal Cancer

Head and Neck Cancer

Singapore
National Cancer Centre, Singapore

Unknown

Cyclophosphamide and Docetaxel or Doxorubicin in Treating Women With Newly Diagnosed Breast Cancer That Can Be Removed by Surgery

Breast Cancer

Singapore
National Cancer Centre, Singapore

Completed

Surgery and Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer That Can Be Removed During Surgery

Head and Neck Cancer

Singapore
National Cancer Centre, Singapore

Unknown

Radiation Therapy Alone Compared to Radiation Therapy Plus Chemotherapy in Treating Patients With Previously Untreated Cancer of the Nasopharynx

Head and Neck Cancer

Singapore
National Cancer Centre, Singapore

Unknown

Cyclophosphamide, Methotrexate, and Prednisolone With or Without Aromatase Inhibitor Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer

Breast Cancer

Singapore
National Cancer Centre, Singapore
Khoo Teck Puat Hospital; National Heart Centre Singapore

Not yet recruiting

Timely Interventions to Enable and Reach Patients With Heart Failure, and Their Caregivers With Palliative Care (TIER-HF-PC)

Heart Failure

Singapore
National Cancer Centre, Singapore
Singapore Translational Cancer Consortium; Genome Institute of Singapore; Cancer...

Recruiting

Phase-2 Dacomitinib Study on Patients With EGFR-Driven Advanced Solid Tumours With Low EGFR-AS1 IncRNA Expr or Other Novel Emerging Biomarkers

Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Advanced Solid Tumours

Singapore
National University, Singapore
Singapore Cancer Society; National University Cancer Institute, Singapore

Completed

SMS Reminders to Improve Medication Adherence of Aromatase Inhibitors

Breast Cancer | Medication Adherence

Singapore
Singapore National Eye Centre
National University, Singapore

Completed

Treatment of Meibomian Gland Dysfunction

Meibomian Gland Dysfunction (MGD)

Singapore
National Cancer Centre, Singapore
MSD Pharma (Singapore) Pte Ltd

Recruiting

Phase II Lenvatinib and Pembrolizumab in Endocrine Resistant Breast Cancer With Letrozole (LaPemERLA)

Hormone Receptor-Positive HER2-Negative Advanced Breast Cancer

Singapore
National Cancer Centre, Singapore
Singapore General Hospital; A*Star

Completed

Pilot Study of Somatostatin Receptor Imaging in Nasopharyngeal Cancer

Nasopharyngeal Carcinoma

Singapore
National Heart Centre Singapore
National University, Singapore

Unknown

Association of Midlife Dietary and Lifestyle Factors on Cardiac Functional Changes in the Elderly (CardiacAging)

Ageing

Singapore
Singapore National Eye Centre
National University, Singapore

Completed

Assessment of Fibrin Glue in Pterygium Surgery and Other Forms of External Eye Surgery

Pterygium | Ocular Surface Cicatrizing Diseases

Singapore
National Cancer Centre, Singapore
National Taiwan University Hospital; National University of Singapore

Recruiting

Phase 2 Trial of Ipilimumab and Nivolumab in Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore; Ministry of Health, Singapore

Active, not recruiting

ENABLE (Educate, Nurture, Advise, Before Life Ends) Intervention for Heart Failure (HF) Patients and Their Caregivers in Singapore (ENABLE-HF-SG)

Heart Failure

Singapore
Singapore National Eye Centre
National University Hospital, Singapore

Completed

Analysis of the Pachychoroid Phenotype in an Asian Population

Pachychoroid Disease

Singapore
Singapore National Eye Centre
National University Hospital, Singapore

Unknown

Argon Laser Peripheral Iridoplasty for Primary Angle Closure Glaucoma (ALPI)

Glaucoma

Singapore
National University of Singapore
National Heart Centre Singapore

Completed

Rapid Eye Movement Related OSA in Diabetic Versus Non-Diabetic Patients Treated With PCI

Coronary Artery Disease | Diabetes Mellitus | Obstructive Sleep Apnea

Singapore
National Heart Centre Singapore
National University Hospital, Singapore

Unknown

SAPhIRE Statin Adverse Drug Reaction (STATIN)

Myopathy

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore; ASLAN Pharmaceuticals

Active, not recruiting

ASLAN001 in Combination With Oxaliplatin and Capecitabine or Oxaliplatin and 5-FU With Leucovorin

Solid Tumors

Singapore
National Heart Centre Singapore

Recruiting

An Updated Wearable Magnetic Flux Device to Optimize Blood Pressure Control

Hypertension

Singapore
National Heart Centre Singapore

Recruiting

Exercise to Slow Cardiovascular Ageing Progression

Exercise | Cardiovascular | Cardiac Ageing

Singapore
National Heart Centre Singapore

Recruiting

Electroacupuncture for Heart Protection: Clinical Application in Patients Undergoing Cardiac Bypass Surgery (EA-CABG)

Coronary Artery Disease | Electro-Acupuncture

Singapore
National Heart Centre Singapore

Recruiting

The Cardio-Sarcopenia Study

Physical Activity | Sarcopenia | Older Adults | Cardiac Ageing

Singapore
National Heart Centre Singapore

Recruiting

Effects of Physical Activity, Ambulatory Blood Pressure and Calcium Score on Cardiovascular Health in Normal People (SingHEART)

Myocardial Infarction

Singapore
Singapore National Eye Centre

Active, not recruiting

Topical 2% Ganciclovir Eye Drop for CMV Anterior Uveitis / Endotheliitis

Cytomegalovirus Infections

Singapore
National Heart Centre Singapore

Unknown

Plaque mOrphology iMpact on Side Branch Occlusion at oPtical Coherence Tomography Evaluation in Percutaneous Coronary Interventions (POMPEI)

Percutaneous Coronary Intervention | Bifurcation

Singapore
National Heart Centre Singapore

Completed

Diagnosis of Pulmonary Hypertension Using Cardiac Magnetic Resonance Images

Pulmonary Hypertension

Singapore

Clinical Trials Sponsored by National Cancer Centre, Singapore

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