Search clinical trials for: Atherosclerotic Cardiovascular Disease (ASCVD)

Total 384672 results

Amgen

Completed

A Cross-sectional Study of Lipoprotein(a) Levels in Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD)

Atherosclerotic Cardiovascular Disease

Canada, United States, Belgium, Spain, China, Korea, Republic of, Australia, Netherlands, Austria, Czechia, Taiwan, Hungary, Italy, Portugal, United Kingdom, Greece, Hong Kong, Turkey, France, Bulgaria, Germany, Finland, Japan, Sweden, ... and more
Novartis Pharmaceuticals

Not yet recruiting

VictORION-INCLUSION is a Multicenter, Randomized, Open Label, Study of Inclisiran + Usual Care vs Usual Care Alone in an Inclusive and Underrepresented Population at High Risk for or Diagnosed With ASCVD Within a Pragmatic EHR Framework. (V-INCLUSION)

Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals

Not yet recruiting

Lp(a) Lowering Study of Pelacarsen (TQJ230) in US Black/African American and Hispanic Participants With Elevated Lp(a) and Established ASCVD

Elevated Lp(a) and Established Atherosclerotic Cardiovascular Disease
Holy Cross Hospital, Florida

Unknown

Cardiometabolic Syndrome Response to Therapeutic Lifestyle Changes (COSMETIC)

Metabolic Syndrome | Lifestyle Risk Reduction | ASCVD

United States
Jordan Collaborating Cardiology Group
The Cardiovascular Academy Group of the JCS; The Jordan Cardiac Society (JCS); Istishari Hospital Department of Clinical Research

Terminated

Cardiovascular Risk Categories and Attaining LDL-C Targets in Middle Eastern Adults Aged 30-55 Years of Age (CREATE)

Atherosclerotic Cardiovascular Risk | Low-density-lipoprotein (LDL) Cholesterol

Jordan
Novartis Pharmaceuticals

Not yet recruiting

A Clinical Study to Evaluate the Safety and Effectiveness of Inclisiran Sodium in Indian Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia

Mixed Dyslipidemia | Primary Hypercholesterolemia
Weill Medical College of Cornell University

Not yet recruiting

Telehealth Group Counseling and Preventive Care for Women

Myocardial Infarction | Coronary Artery Disease | Chest Pain | Acute Coronary Syndrome | Unstable Angina | STEMI | NSTEMI | ASCVD

United States
NewAmsterdam Pharma

Recruiting

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies (TANDEM)

Dyslipidemias | Hypercholesterolemia | Familial Hypercholesterolemia | High Cholesterol | ASCVD

United States
Novartis Pharmaceuticals

Completed

Study in Primary Care Evaluating Inclisiran Delivery Implementation + Enhanced Support (SPIRIT)

Atherosclerotic Cardiovascular Disease | Atherosclerotic Cardiovascular Disease Risk Equivelents | Elevated Low Density Lipoprotein Cholesterol

United Kingdom
CSL Behring

Enrolling by invitation

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

End Stage Kidney Disease | Atherosclerotic Cardiovascular Disease

United States, Australia, Belgium, Canada, Germany
NewAmsterdam Pharma

Active, not recruiting

Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies (BROADWAY)

Dyslipidemias | Hypercholesterolemia | Familial Hypercholesterolemia | Atherosclerotic Cardiovascular Disease | High Cholesterol

United States, Poland, Denmark, Czechia, China, Netherlands, Japan, Georgia
Monash University
Novartis Pharmaceuticals

Recruiting

VICTORION-ASCERTAIN: Implementation Study (v-ASCERTAIN) (v-ASCERTAIN)

Cerebrovascular Disease | Coronary Heart Disease (CHD) | Peripheral Arterial Disease (PAD) | Atherosclerotic Cardiovascular Disease (ASCVD)

Australia
Novo Nordisk A/S

Enrolling by invitation

A Study to Understand the Real-world Awareness and Perceptions of Systemic inFLAMmation and rolE of hsCRP as a Biomarker in Patients With AtheroSclerotic CardioVascular Disease and Chronic Kidney Disease Among Nephrologists

Systemic Inflammation | Chronic Kidney Disease (CKD) | Atherosclerotic Cardiovascular Disease (ASCVD)

United States
Chinese Academy of Medical Sciences, Fuwai Hospital

Recruiting

Intensive Lipid-lowering for Plaque and Major Adverse Cardiovascular Events in Low to Intermediate 10-year ASCVD Risk Population (ILLUMINATION)

Coronary Artery Disease Progression

China
Brigham and Women's Hospital

Active, not recruiting

Randomized Controlled Trial of Alert-Based Computerized Decision Support for Optimizing Low-Density Lipoprotein Management (LDL-ALERT)

ASCVD | Hyperlipemia, Mixed

United States
Brigham and Women's Hospital
Patient-Centered Outcomes Research Institute

Recruiting

PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes (PRECIDENTD)

Type2Diabetes | ASCVD

United States
Novo Nordisk A/S

Completed

A Multinational Survey-based Study to Understand the Real-world Awareness and Perceptions of Systemic inFLAMmation and rolE of hsCRP as a Biomarker in Patients With AtheroSclerotic CardioVascular Disease and Chronic Kidney Disease Among Cardiologists (FLAME-ASCVD)

Chronic Kidney Disease (CKD) | Atherosclerotic Cardiovascular Disease (ASCVD)

India
Novartis Pharmaceuticals

Recruiting

Study Evaluating Effectiveness and Adherence of Inclisiran Plus Standard of Care (SoC) Lipid-lowering Therapy Compared to SoC in ASCVD (VICTORION REAL)

Mixed Dyslipidemia | Primary Hypercholesterolemia

Switzerland, Saudi Arabia, United Arab Emirates, United Kingdom, Austria, Israel, China, Malaysia
Eli Lilly and Company

Recruiting

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Overweight and Obesity

United States, Australia, Italy, Hungary, Spain, Canada, Germany, Argentina, Belgium, Czechia, Greece, Israel, Austria, Brazil, Mexico, Netherlands, Romania, India, United Kingdom, Slovakia, Poland, Turkey, Puerto Rico, France, Denmark
Novartis Pharmaceuticals

Active, not recruiting

Efficacy and Safety of Inclisiran as Monotherapy in Chinese Adults With Low or Moderate ASCVD Risk and Elevated Low-density Lipoprotein Cholesterol. (V-Mono China)

Primary Hypercholesterolemia or Mixed Dyslipidemia

China
Masonic Cancer Center, University of Minnesota

Withdrawn

Ph1 Study of FT538 Alone and With Vorinostat for Persistent Low-Level HIV Viremia

HIV-1-infection | ART | Interleukin | Cd4+ Lymphocyte Deficiency | Lymphoid Tissue; Infection

United States
The HIV Netherlands Australia Thailand Research...
Police General Hospital; Faculty of Medical Sciences, Radboud University of... and other collaborators

Completed

Switching From Protease Inhibitor/Ritonavir to Generic Single Tablet Regimen of Tenofovir Alafenamide/Emtricitibine/Dolutegravir

HIV

Thailand
Indiana University

Recruiting

Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors

Coronary Artery Disease | Cisplatin Adverse Reaction | Lipid Disorder | Survivorship | Hypogonadism, Male | Testicular Cancer | Bone Marrow Transplant Complications | ASCVD

United States
Duke University
Sanofi; Regeneron Pharmaceuticals

Completed

Patient and Provider Assessment of Lipid Management Registry (PALM)

Smoking | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Peripheral Arterial Disease | Atherosclerosis | Carotid Stenosis | Hypercholesterolemia | Hyperlipidemia | Claudication | Unstable Angina | Coronary Artery Disease (CAD) | Chronic Kidney Disease (CKD) | Angina | Transient Ischemic Attack (TIA) | Myocardial...

United States
Sohag University
Emory University

Not yet recruiting

Predictors of Intracranial Atherosclerotic Disease in Posterior Circulation: a Cohort Study

Stroke, Ischemic | Intracranial Atherosclerosis | Posterior Circulation Brain Infarction

Egypt, United States
Peking University First Hospital

Recruiting

Fractional Flow Reserve-guided Stenting Versus Medical Therapy in Atherosclerosis Renal Artery Stenosis (FAIR)

Renal Artery Stenosis Atherosclerotic | Secondary Hypertension Renal Arterial

China
Zhujiang Hospital
Guangzhou First People's Hospital; Guangdong Provincial People's Hospital; Shenzhen... and other collaborators

Not yet recruiting

Interleukin-6 Receptor Inhibition for Symptomatic Intracranial Atherosclerosis (IRIS-sICAS)

Ischemia | Stroke | Brain Diseases | Ischemic Stroke | Cerebral Infarction | Atherosclerosis of Artery | Atheroscleroses, Intracranial
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Shenzhen Hospital of Southern Medical University

Not yet recruiting

Immediate Angioplasty For Acute Ischemic Stroke With Severe Intracranial Atherosclerotic Stenosis (MAGIC)

Stroke, Acute Ischemic

China
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
University of Alberta
Heart and Stroke Foundation of Canada

Not yet recruiting

Fish Oil, Metformin and Heart Health in PCOS

Cardiovascular Disease | PCOS | Cardiac Hypertrophy | Atherosclerotic Cardiovascular Disease | Atherosclerotic Plaque
Zhujiang Hospital

Recruiting

The Correlation of Intracranial Artery Calcification and Outcomes of Mechanical Thrombectomy (CAIS-MT)

Vascular Diseases | Stroke | Cerebrovascular Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Ischemic Stroke | Stroke, Acute | Intracranial Arterial Calcification

China
Yong He

Not yet recruiting

Preventive Intervention Value of Inclisiran Combined With DCB in Vulnerable Coronary Atherosclerotic Plaques

Acute Coronary Syndrome
Assistance Publique Hopitaux De Marseille

Recruiting

Prospective Multicenter Cohort Study to Validate Four Groups of Biomarkers for Assessing Lung Cancer Risk Among Patients With Atheromatous Cardiovascular Disease in a Screening Pathway (BIOCEPTION)

Lung Cancer | Smoking-related Pathology | Atheroma | Non-progressive Cancer > 5 Years

France
Novartis Pharmaceuticals

Not yet recruiting

Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction (V-ACCELERATE)

Plaque, Atherosclerotic
Harbin Medical University
Shanghai Shenqi Medical Technology Co., Ltd

Recruiting

Preventive Drug-coated Balloon Angioplasty in Vulnerable Atherosclerotic Plaque (RESTORE Trial)

Acute Coronary Syndrome (ACS)

China
Centro Cardiologico Monzino
Politecnico di Milano; Azienda Ospedaliero-Universitaria Consorziale Policlinico...

Recruiting

Computational mOdelliNg of myoCardial pERfusion to Improve ouTcome Prediction Based on cOronary Artery Stenosis and Atherosclerotic Plaque Burden Assessment by Computed Tomography (CONCERTO)

Chronic Coronary Syndrome

Italy
First Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

Efficacy of Butylphthalide on Symptomatic Atherosclerotic Stenosis in Middle Cerebral Artery (SICAS)

Ischemic Stroke, Acute | Intracranial Atherosclerosis

China
Kayseri City Hospital

Not yet recruiting

Effects of Aerobic Exercise in Obese Patients With Atherosclerotic Cardiovascular Disease

Coronary Artery Disease | Obesity

Turkey
Niguarda Hospital
Istituto di Fisiologia Clinica CNR

Recruiting

Vascular Senescence and Atherosclerotic Plaque Vulnerability (VICTORIA)

Coronary Artery Disease

Italy
NewAmsterdam Pharma

Not yet recruiting

A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque (REMBRANDT)

Coronary Artery Disease | Plaque, Atherosclerotic | Lipidemia
Azienda Ospedaliera Città della Salute e della...
Compagnia di San Paolo

Not yet recruiting

The AI-CAC Model for Subclinical Atherosclerosis Detection on Chest X-ray (AI-CAC-PVS)

Cardiovascular Diseases | Atherosclerosis | Coronary Artery Calcification
Amgen

Recruiting

A Study Assessing Repatha® in Combination With Standard of Care (SOC) Compared With SOC on Major Cardiovascular Events in Chinese Participants With Atherosclerotic Cardiovascular Disease

Major Cardiovascular Event | Established Atherosclerotic Cardiovascular Disease

China
University of Louisville

Recruiting

Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP) (ARTCAP)

Coronary Artery Disease | Atherosclerosis | Heart Attack

United States
Medical University of Warsaw
University College, London; Queen Mary University of London; National Science...

Recruiting

Comprehensive Assessment of Morphometric, Functional, Biomechanical and Biological Interactions Between Atherosclerotic Plaque and Platelets Within the Stenosed Coronary Artery (INTERFORCE)

Atherosclerosis | Chronic Coronary Syndrome

Poland
Mei Gao

Not yet recruiting

Factors Related to the Progression of Non-target Coronary Lesions

Coronary Stenosis
Istituti Clinici Scientifici Maugeri SpA
Società Italiana Cardiologia Ospedalità Accreditata (SICOA)

Recruiting

PAtients With Symptomatic Peripheral Artery Disease on Rivaroxaban-acetylsalicylic Acid Combination Therapy (PRO-PAS) (PRO-PAS)

Peripheral Atherosclerotic Disease

Italy
UPECLIN HC FM Botucatu Unesp

Recruiting

Shear Wave Elastography for Carotid Atherosclerotic Plaques

Carotid Atherosclerosis

Brazil
University of Pennsylvania
Doris Duke Charitable Foundation

Not yet recruiting

A Mechanistic Clinical Trial of Colchicine in Patients Undergoing Femoral Endarterectomy

Peripheral Artery Disease

United States
Jordan Collaborating Cardiology Group
The Jordan Cardiovascular Research Group JoCVRG; Yarmouk University School...

Recruiting

Cardiovascular Patients With no Standard Modifiable Risk Factors (SMuRF-less-ME1)

Cardiovascular Risk Factors

Jordan
Xuanwu Hospital, Beijing
National Key Research and Development Project, China

Recruiting

Effects of Medical Treatment of ICAS With Hemodynamic Disorders Based on MR-FFR

Stroke, Ischemic | Intracranial Atherosclerosis

China

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