Search clinical trials for: RANK

Total 284 results

Syros Pharmaceuticals

Recruiting

Tamibarotene Plus Azacitidine in Participants With Newly Diagnosed RARA-positive Higher-Risk Myelodysplastic Syndrome

Myelodysplastic Syndromes

United States, Spain, Belgium, Israel, France, United Kingdom, Austria, Czechia, Italy, Poland, Canada, Hungary, Germany
Takeda

Recruiting

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Crohn's Disease (CD)

United States, Australia, Israel, Belgium, Hungary, Canada, China, Croatia, Czechia, Greece, Italy, Japan, Korea, Republic of, Poland, United Kingdom, Lithuania, Slovakia, Spain
Takeda

Recruiting

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Ulcerative Colitis (UC)

Colitis, Ulcerative

United States, Israel, Canada, Italy, United Kingdom, Hungary, Japan, Australia, China, Greece, Belgium, Croatia, Korea, Republic of, Poland, Czechia
Charite University, Berlin, Germany
Ludwig-Maximilians - University of Munich; University Medicine Greifswald; University... and other collaborators

Recruiting

Spironolactone In The Treatment of Heart Failure (SPIRIT-HF)

Heart Failure With Preserved Ejection Fraction | Heart Failure With Mid-range Ejection Fraction

Austria, Germany, Netherlands, France, Serbia
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Austrian Breast & Colorectal Cancer Study...

Recruiting

Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation (BRCA-P)

Neoplasms | Breast Cancer | Breast Neoplasms | Breast Diseases | Breast Carcinoma | BRCA1 Mutation

United States
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Recruiting

Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia (MILOS)

Hypercholesterolemia | Mixed Dyslipidemia

Austria, United Kingdom, Italy, Germany, Belgium
University Hospital, Essen
Noscendo GmbH, Germany; Health Economics and Health Care Management, Bielefeld... and other collaborators

Recruiting

Optimization of Sepsis Therapy Based on Patient-specific Digital Precision Diagnostics (DigiSep)

Sepsis | Septic Shock

Germany
Zydus Therapeutics Inc.

Recruiting

A Pharmacokinetic Study of Saroglitazar Magnesium in Subjects With Severe Renal Impairment and Normal Renal Function

Renal Impairment

United States
Valent Technologies, LLC

Recruiting

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

Ewing Sarcoma | Medulloblastoma | Neuroblastoma | Solid Tumors | Rhabdomyosarcoma | Hepatoblastoma

United States
University College, London
Bone Cancer Research Trust

Recruiting

ICONIC: Improving Outcomes Through Collaboration in OsteosarComa (ICONIC)

Osteosarcoma

United Kingdom
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study

Asthma

United States
Washington University School of Medicine
National Institutes of Health (NIH)

Recruiting

RANKL Inhibition and Mammographic Breast Density (TRIDENT)

Dense Breasts

United States
European Organisation for Research and Treatment...
Canadian Cancer Trials Group; ECOG-ACRIN Cancer Research Group; Japan Clinical... and other collaborators

Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma (STRASS2)

Leiomyosarcoma | Liposarcoma | Retroperitoneal Sarcoma

United States, Japan, Spain, France, Canada, Italy, United Kingdom, Germany, Czechia, Cyprus, Netherlands, Australia, Poland, Slovakia, Denmark
Population Health Research Institute

Recruiting

EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF) (ENRICH-AF)

Atrial Fibrillation | Intracranial Hemorrhages

Spain, Germany, United States, Belgium, United Kingdom, Switzerland, Egypt, Canada, Austria, China, Czechia, India, Nepal, Portugal, Argentina
University of Ulm
Jazz Pharmaceuticals

Recruiting

Study of Standard Intensive Chemotherapy Versus Intensive Chemotherapy With CPX-351 in Adult Patients With Newly Diagnosed AML and Intermediate- or Adverse Genetics

Acute Myeloid Leukemia

Austria, Germany
Icahn School of Medicine at Mount Sinai
National Institute on Drug Abuse (NIDA)

Recruiting

Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk (MPH-ATX)

ADHD | Attention Deficit Hyperactivity Disorder

United States
Kirby Institute
National Health and Medical Research Council, Australia

Recruiting

ETHOS ENGAGE: Enhancing Treatment of Hepatitis C in Opioid Substitution Settings (ETHOS II)

Hepatitis C

Australia
Nicola Goekbuget

Recruiting

Inotuzumab Ozogamicin and Conventional Chemotherapy In Patients Aged 56 Years and Older With ALL

Precursor Cell Lymphoblastic Leukemia

Germany
Norwegian University of Science and Technology
St. Olavs Hospital; Alesund Hospital; Namsos Hospital; Volvat Medisinsk Senter...

Recruiting

Bariatric Surgery and Pharmacokinetics of Methylphenidate

Obesity, Morbid

Norway
Technische Universität Dresden

Recruiting

Clinical AML Registry and Biomaterial Database of the Study Alliance Leukemia (SAL)

Acute Myeloid Leukemia (AML)

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Ramucirumab Plus FOLFIRI Versus Ramucirumab Plus Paclitaxel in Patients With Advanced or Metastatic Gastric Cancer, Who Failed One Prior Line of Palliative Chemotherapy (RAMIRIS)

Advanced Gastric or EGJ Cancer

Germany, Austria, Italy
Prof. Dr. M. Dreyling (co-chairman)
LMU Klinikum

Recruiting

ASCT After a Rituximab/Ibrutinib/Ara-c Containing iNduction in Generalized Mantle Cell Lymphoma

Mantle Cell Lymphoma

Germany, Sweden, Denmark, Italy, Norway
University of Sydney
Peking University People's Hospital; Institute for Clinical Evaluative Sciences and other collaborators

Recruiting

Randomised Evaluation of Sodium Dialysate Levels on Vascular Events (RESOLVE)

End-Stage Kidney Disease

Australia, Canada, United Kingdom, Malaysia, Germany, India
University of Ulm

Recruiting

Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms, and Higher Risk Myelodysplastic Syndrome - The Biology and Outcome (BiO)-Project (AMLSG BiO)

Acute Myeloid Leukemia (AML) | Higher Risk Myelodysplastic Syndromes (MDS With Excess Blasts 2)

Austria, Germany
Vesile Elif Toy
Inonu University

Completed

Vitamin-D Insufficiency and Implants

Vitamin D Deficiency | Peri-Implantitis | Osseointegration Failure of Dental Implant

Turkey
Hoffmann-La Roche
Genentech, Inc.; Breast International Group

Active, not recruiting

A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer (APHINITY)

Breast Cancer

United States, Belgium, Canada, Australia, Austria, Bulgaria, China, Croatia, Denmark, France, Germany, Guatemala, Hungary, Ireland, Italy, Korea, Republic of, Panama, Slovenia, Spain, Taiwan, United Kingdom, Colombia, Czechia, El Salvador and more
Boston Medical Center
Medtronic; Society of Vascular and Interventional Neurology

Completed

CT (Computerized Tomography) for Late EndovasculAr Reperfusion (CLEAR)

Stroke, Cardiovascular

United States, Belgium, Finland, Germany, Canada, Switzerland, Japan, Portugal, France, Spain
Boston Medical Center
Heidelberg University

Completed

Posterior cerebraL ArTery Occlusion Study (PLATO)

Stroke, Acute Ischemic

United States, Switzerland, Germany, Finland, Spain, Italy, Portugal
Novavax

Active, not recruiting

Phase 2/3 Heterologous Boosting Study With Different Dose Levels of Monovalent SARS-CoV-2 rS Vaccines (COVID-19)

COVID-19

United States
Hoffmann-La Roche
Exelixis

Active, not recruiting

Study of Atezolizumab in Combination With Cabozantinib Versus Docetaxel in Patients With Metastatic Non-Small Cell Lung Cancer Previously Treated With an Anti-PD-L1/PD-1 Antibody and Platinum-Containing Chemotherapy (CONTACT-01)

Carcinoma, Non-Small-Cell Lung

United States, France, Belgium, United Kingdom, Australia, Korea, Republic of, Austria, Italy, Portugal, Spain, Poland, Japan, Germany, Greece, Russian Federation
M.D. Anderson Cancer Center

Active, not recruiting

A PHASE IB STUDY OF IMMUNOTHERAPY WITH EX VIVO PRE-ACTIVATED AND EXPANDED CB-NK CELLS IN COMBINATION WITH CETUXIMAB, IN COLORECTAL CANCER PATIENTS WITH MINIMAL RESIDUAL DISEASE (MRD)

Colon Cancer | Resected Stage

United States
James Isaacs, MD

Suspended

Efficacy & Safety for LN144 With Pembrolizumab With High Risk Stage IIIb-dResectable Melanoma

Stage IIIB Melanoma | Stage IIIC Melanoma | Stage IIID Melanoma

United States
AstraZeneca

Active, not recruiting

A Study of Neoadjuvant/Adjuvant Durvalumab for the Treatment of Patients With Resectable Non-small Cell Lung Cancer (AEGEAN)

Non-Small Cell Lung Cancer

Belgium, Italy, Spain, United States, Poland, India, Taiwan, Thailand, Vietnam, Canada, France, Germany, Korea, Republic of, Brazil, Hungary, Japan, Mexico, Peru, Philippines, Russian Federation, China, Austria, Chile, Netherlands, Bulg... and more
Jay S. Skyler
University of Florida; University of California, San Francisco; Diabetes Research...

Withdrawn

Low-dose IL-2 in Established T1D - The "PROREG" Study

Diabetes | Diabetes Mellitus, Type 1 | Diabetes, Autoimmune

United States
Amgen

Completed

Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004

Giant Cell Tumor of Bone

Australia, France, United States, Spain, Italy, Poland, Sweden, United Kingdom
Huizhou Municipal Central Hospital

Completed

Prospective Study on Safety and Efficacy of Stenting for Chronic Middle Cerebral Artery Occlusion With Limb Dysfunction

National Institutes of Health Stroke Scale | Chronic Middle Cerebral Artery Occlusion | Stenting Treatment | Modified Rankin Scale

China
COVID-19 Prevention Network
National Institute of Allergy and Infectious Diseases (NIAID); Medical Research...

Completed

Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern (CoVPN3008)

HIV Infections | COVID-19 | SARS-CoV-2 Infection

Uganda, Malawi, South Africa, Botswana, Zambia, Kenya, Swaziland
AstraZeneca
Merck Sharp & Dohme LLC; NRG Oncology; Breast International Group; Myriad Genetic... and other collaborators

Active, not recruiting

Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer (OlympiA)

Breast Cancer

United States, Austria, Italy, Spain, Sweden, United Kingdom, Belgium, Poland, France, Switzerland, Canada, Germany, Korea, Republic of, Netherlands, Japan, China, Taiwan, Australia, Argentina, Israel, Hungary, Portugal, Iceland, Puerto...
AstraZeneca

Active, not recruiting

Study of Neoadjuvant Olaparib Monotherapy and Olaparib and Durvalumab Combination in HER2 Negative BRCAm Breast Cancer (OlympiaN)

Breast Cancer

United States, Belgium, Italy, Spain, United Kingdom, Germany, Austria, Israel, Australia
Assistance Publique - Hôpitaux de Paris
CEREMAST

Completed

Interest of Denosumab Treatment in Osteoporosis Associated to Systemic Mastocytosis (DenosuMast)

Osteoporosis | Systemic Mastocytosis

France
Bio 54, LLC

Completed

Treatment of Post-Punch Biopsy Bleeding in Apixaban-Treated Patients Using Self-Administered BXP154B

Wound Bleeding

United States
Arbeitsgemeinschaft medikamentoese Tumortherapie
Amgen

Completed

Patients With Newly Diagnosed Multiple Myeloma Comparing KTd vs. KRd Induction Therapy and Investigating a K-mono Maintenance Strategy

Multiple Myeloma

Austria, Germany
Pinar Yasar

Completed

The Relationship Between Urinary Incontinence and Motor Symptoms

Stroke | Urinary Incontinence | Motor Skills Disorders

Turkey
TC Erciyes University

Completed

The Effect Of Vertical Releasing Incision On Implant Procedures (Vertikal)

Bone Loss | Flap Design

Turkey
University of Washington
Frankel Family Foundation; Stewardship Foundation

Active, not recruiting

Leading Advancements in the Uptake of Newborn Community Health (LAUNCH)

Breastfeeding, Exclusive | Immunization; Infection | Growth; Stunting, Nutritional

Ethiopia
Ataturk University

Completed

Effect of Calcium Silicate Based Root Canal Medicament on Inflammatory Mediators

Periapical; Infection

Turkey
University of New Mexico

Withdrawn

Impact of Clinical Pharmacy Services on Medication Cost and Hospitalization Rates in Hemodialysis Patients

End Stage Renal Disease
MorphoSys AG

Active, not recruiting

Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients (frontMIND)

Diffuse Large B-cell Lymphoma

Germany, France, Hungary, Italy, Spain, United States, Austria, Czechia, Australia, Israel, Korea, Republic of, Turkey, Taiwan, Argentina, Canada, Colombia, Ireland, Japan, Malaysia, New Zealand, Philippines, Poland, Romania, Russian... and more
Novartis Pharmaceuticals

Active, not recruiting

Nilotinib Treatment-free Remission Study in CML (Chronic Myeloid Leukemia) Patients (ENESTfreedom)

Chronic Myelogenous Leukemia

Belgium, Spain, Austria, Germany, Italy, France, Netherlands, Sweden, Japan, United States, Greece, United Kingdom, Bulgaria, Hungary, Argentina, Poland, Colombia, Ireland, Denmark
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Treatment of High and Very High riSk Dyslipidemic pAtients for the PreveNTion of CardiOvasculaR Events (SANTORINI)

Cardiovascular Diseases | Dyslipidemia | Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

Finland, Netherlands, Spain, Belgium, Sweden, Austria, United Kingdom, Switzerland, Denmark, France, Germany, Portugal, Italy, Ireland

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