Search clinical trials for: Sustained response off treatment

Total 85495 results

Mesoblast, Ltd.
PPD

Completed

A Multi-center Study a Single IV Infusion of Allogeneic MPCs in Patients With Rheumatoid Arthritis and Incomplete Response to at Least One TNFα Inhibitor

Rheumatoid Arthritis

United States, Australia
Leading BioSciences, Inc

Terminated

Treatment of Septic Shock by Inhibiting Autodigestion and Preserving Gut Integrity With Enteric LB1148 (SSAIL)

Septic Shock

United States, Canada
Genentech, Inc.

Completed

A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)

Multiple Sclerosis, Relapsing-Remitting

United States, Canada
P1vital Products Limited

Completed

Predicting Response to Depression Treatment (PReDicT)

Depression

Spain, France, Germany, United Kingdom, Netherlands
VA Office of Research and Development

Completed

Genetic Predictors of Lithium Response in Bipolar Disorder

Bipolar Disorder

United States
Germans Trias i Pujol Hospital
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la...

Completed

Peginterferon Alfa-2a, Ribavirin and Epoetin β in Coinfected Patients HCV/HIV Not Responding to Previous Treatment Regimens

HIV Infections | Hepatitis C

Spain
VA Office of Research and Development

Completed

Dosage and Predictors of Naming Treatment Response in Aphasia

Stroke | Aphasia

United States
AbbVie

Completed

Quality of Life Measurement in Treatment Naïve Patients With Hepatitis C Virus (HCV) Genotype 1 (GT1) Suffering From Fatigue and Receiving Ombitasvir, Paritaprevir, and Ritonavir and Dasabuvir (Viekirax®/Exviera®) (HEMATITE)

Chronic Hepatitis C Virus (HCV)

Switzerland
AbbVie

Completed

Efficacy and Safety of 8-weeks of Glecaprevir/Pibrentasvir in Treatment-Naïve Adults With HCV Genotype 1-6 and Aspartate Aminotransferase to Platelet Ratio Index (APRI) ≤1

Hepatitis C Virus (HCV)

United States, Bulgaria, Canada, France, Germany, Poland, Puerto Rico, Russian Federation, Spain, United Kingdom
VA Office of Research and Development

Completed

Brain Biomarkers of Response to Treatment for Apraxia of Speech (SPT)

Stroke | Aphasia

United States
Genentech, Inc.
Roche Pharma AG

Terminated

A Study of Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Who Don't Have a Response to Anti-TNF-α Therapy (SCRIPT) (SCRIPT)

Rheumatoid Arthritis

United States, Belgium, Canada, Hungary, Argentina, Germany, Spain, Brazil, Poland, Israel, Mexico, Japan, France, Peru, Switzerland, Sweden, Italy, Australia, New Zealand, Panama, Czechia, Netherlands, Slovakia, Slovenia, Taiwan
Seoul National University Hospital
IlDong Pharmaceutical Co Ltd

Completed

Treatment Response of High-dose and Standard-dose Rabeprazole for Extra-esophageal Reflux.

Esophageal Disease

Korea, Republic of
Foundation for Liver Research

Completed

Lowering Viral Load With Nucleos(T)Ide Analogues Prior to Peginterferon Treatment to Ncrease Sustained Response in CHB (PEGON)

Chronic Hepatitis B

Netherlands, China
Gilead Sciences

Completed

Ledipasvir/Sofosbuvir Fixed-Dose Combination With Ribavirin or GS-9669 in Subjects With Chronic Genotype 1 HCV Infection

Chronic HCV Infection

United States
Gilead Sciences

Completed

Safety and Efficacy of LDV/SOF Fixed-Dose Combination (FDC) ± Ribavirin in HCV Genotype 1 Subjects

Chronic Hepatitis C Virus

United States
Gilead Sciences

Completed

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin in Treatment-Experienced Subjects With Genotype 1 HCV Infection (ION-2)

Chronic Hepatitis C Virus

United States
Gilead Sciences

Completed

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination (FDC) With and Without Ribavirin for the Treatment of HCV

Chronic Hepatitis C Virus

United States, France, Italy, United Kingdom, Germany, Spain, Puerto Rico
Gilead Sciences

Completed

Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination Tablet With Ribavirin for 12 Weeks in Treatment-naive Adults With Chronic HCV Genotype 3 Infection

Hepatitis C Virus Infection

Canada
Gilead Sciences

Completed

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin for the Treatment of HCV (ION-3)

Chronic Hepatitis C Virus

United States
Getz Pharma
Dimension Research

Completed

Evaluation of Unipeg® for Response and Ongoing Safety in Pakistani Population (EUROP)

Hepatitis C
National Institutes of Health Clinical Center (CC)

Completed

Community-based Treatment of Chronic Hepatitis C Monoinfection and Coinfection With HIV in the District of Columbia

HCV HIV

United States
VA Office of Research and Development
University of Michigan

Completed

Interactive Voice Response (IVR)-Based Treatment for Chronic Low Back Pain

Chronic Low Back Pain

United States
Massachusetts General Hospital

Completed

Biological Markers of Response to Treatment in Major Depressive Disorder

Major Depressive Disorder
The Cleveland Clinic
GlaxoSmithKline; Currax Pharmaceuticals

Completed

Does Treximet Improve Productivity and Patient Satisfaction Due to Sustained Response and Consistency of Response?

Workplace Migraine Treatment

United States
Pfizer

Completed

A Study to Assess Immune Response Following Zoster Vaccination to Subjects With Rheumatoid Arthritis Receiving Tofacitinib or Placebo With Background Methotrexate

Rheumatoid Arthritis

United States
Kawin Technology Share-holding Co., Ltd.
KawinGreen Biotech Co., Ltd.

Completed

Safety and Efficacy of Generic Sofosbuvir and Ribavirin for Treatment-naive Genotype 2 Chronic Hepatitis C (SOF_GT2)

Hepatitis C, Chronic | Hepatitis C Virus Infection, Response to Therapy of

China
AbbVie (prior sponsor, Abbott)

Completed

A Follow up Study Designed to Obtain Long Term Data on Participants Who Either Achieved a Sustained Virologic Response or Did Not Achieve a Sustained Virologic Response in an AbbVie Sponsored Hepatitis C Study

Hepatitis C
Beijing Ditan Hospital

Unknown

Sustained HBsAg and Viral Response in Patients Achieved HBsAg Loss by Interferon Treatment

Chronic Hepatitis B

China
Acorda Therapeutics

Completed

Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury

Muscle Spasticity | Spinal Cord Injury

United States, Canada
Assiut University

Unknown

Assessment of Patients With Hepatitis C Virus Related Liver Cirrhosis After Sustained Response to Direct Acting Anti Viral Drugs.

Liver Cirrhosis | Hepatitis C

Egypt
ANRS, Emerging Infectious Diseases
Institut Pasteur

Withdrawn

Efficacy and Safety of the Combination Vitamin D With Standard of Care in Egyptian Patients With Untreated Chronic Hepatitis C (ViZIR)

Chronic Hepatitis C

Egypt
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Completed

Antiviral Responses to NNRTI-Based vs. PI-Based ARV Therapy in HIV Infected Infants Who Have or Have Not Received Single Dose NVP for Prevention of Mother-to-Child Transmission of HIV (P1060)

HIV Infections

Uganda, India, Malawi, South Africa, Tanzania, Zambia, Zimbabwe
Pfizer

Completed

A Study Of DVS SR In Treatment Of Children And Adolescent Outpatients With MDD

Major Depressive Disorder

United States, Chile, Mexico
Cubist Pharmaceuticals LLC

Completed

Daptomycin in the Treatment of Subjects With Infective Endocarditis or Bacteremia Due to S. Aureus

Bacteremia | Bacterial Endocarditis
Merck KGaA, Darmstadt, Germany

Completed

Cilengitide and Cetuximab in Combination With Platinum-based Chemotherapy as First-line Treatment for Subjects With Advanced Non Small Cell Lung Cancer (NSCLC) (CERTO)

Carcinoma, Non-Small-Cell Lung

France, Italy, Poland, Spain, Germany, Belgium, Ireland, Czech Republic
University of Washington
National Cancer Institute (NCI)

Completed

PET Scans in Assessing Response To Treatment in Patients Receiving Hormone Therapy or Trastuzumab for Breast Cancer

Breast Cancer

United States
Hoffmann-La Roche

Completed

An Observational Study of Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) on Predictive Values of RVR on Sustained Virological Response in Different Stages of Liver Fibrosis in Treatment-Naïve Patients With Chronic Hepatitis C Genotype 1

Hepatitis C, Chronic

Poland
Valme University Hospital
Hospital Universitario de Canarias; Hospital Universitario Virgen Macarena; Hospital... and other collaborators

Unknown

Real-life Security and Efficacy of DAA-based Therapy in HCV/HIV-Coinfected Patients

Hepatitis C, Chronic | Human Immunodeficiency Virus

Spain
Beijing Ditan Hospital

Completed

The Predictive Value of On-treatment Virological Response for Sustained Virological Response in Chronic Hepatitis C

Chronic Hepatitis C

China
Beijing Ditan Hospital

Unknown

Efficacies of Entecavir Add on HBeAg Negative Patients With HBV DNA Positive During Peginterferon Alpha 2a Treatment

Chronic Hepatitis B

China
Beijing Ditan Hospital

Unknown

Sustained Viral Response in Patients Achieved HBsAg Level≤100 IU/ml After Completed Interferon Treatment

Chronic Hepatitis B

China
University Health Network, Toronto

Terminated

Early Treatment With Sofosbuvir (SOF) and Ledipasvir (LDV) to Prevent HCV Recurrence After Liver Transplantation (OLT)

Hepatitis C Viral Infection

Canada
Hoffmann-La Roche

Completed

A Study of Sustained Virological Response in Relation to IL28-b Expression in Treatment-Naïve Patients With Chronic Hepatitis C Genotype 1 on Combination Treatment With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin)

Hepatitis C, Chronic

Brazil
CHU de Quebec-Universite Laval
Pfizer; Canadian Glaucoma Clinical Research Council

Completed

Impact Post-operative Treatment on Intraocular Pressure Post-SLT on Patients With Primary Open-angle Glaucoma (SLT)

Glaucoma | Inflammatory Response

Canada
The HIV Netherlands Australia Thailand Research...
Chulalongkorn University; National Health Security Office, Thailand

Completed

Children With HIV and Asthma (CHIVAS)

T Cell Response to Asthma in HIV-infected Patients Before and After Starting Treatment

Thailand
University of Roma La Sapienza

Completed

Ribavirin Pre-treatment Followed by Combined Standard Therapy in Hepatitis C Virus (HCV) Recipients (RBV)

Hepatitis C

Italy
Gilead Sciences

Completed

Sofosbuvir Plus Ribavirin Administered for Either 12 or 24 Weeks in Treatment-Naive and Treatment-Experienced Egyptian Adults With Chronic Genotype 4 Hepatitis C Virus (HCV) Infection

Hepatitis C Virus

Egypt
Novartis Pharmaceuticals

Completed

Sustained Virological Response (SVR) to Antiviral Treatment of Liver Transplant Recipients With Recurrent Hepatitis C (SUSTAIN)

Liver Transplantation | Hepatitis C

Spain, Germany, Switzerland, Italy, United States, Korea, Republic of, Canada, Colombia, Belgium, Brazil, France, United Kingdom, Russian Federation
US Department of Veterans Affairs

Completed

Piloting IVR (Interactive Voice Response) for Chronic Pain Treatment

Chronic Pain

United States
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Four Arms, Multicenter Study of Tailored Regimens With Peginterferon Plus Ribavirin for Genotype 2 Chronic Hepatitis C

Chronic Hepatitis C

Taiwan

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