Search clinical trials for: airflow obstruction, plethysmography, lung volumes

Total 64828 results

National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Fasting on the Asthma Inflammasome

Asthma

United States
Imperial College London

Unknown

Physiology and Structure of the Small Airways in Patients With Chronic Airflow Obstruction or COVID-19 (PASSPORT)

COVID-19 | Asthma | Copd | Small Airways Disease

United Kingdom
University Hospital, Montpellier

Active, not recruiting

Effect of Vocal Exercises With Straw on Aerodynamic Parameters of Voice (Pressure, Flow) in Dysodic Singers With Nodules (DYSODIE)

Dysodia | Vocal Disorders

France
Novartis Pharmaceuticals

Completed

A Safety, Tolerability and Efficacy Study With QBW251 in COPD Patients With QBW251

Chronic Obstructive Pulmonary Disease, COPD

Poland, United States
Northumbria University
North Tyneside General Hospital

Completed

Effect of Portable NIV on Operational Chest Wall Volumes in COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Corporacion Parc Tauli

Terminated

Preventive Strategies in Acute Respiratory Distress Syndrome (ARDS) (EPALI)

ARDS

Spain
University of Illinois at Chicago
National Heart, Lung, and Blood Institute (NHLBI)

Completed

COPD Assessment and Management Bundle Versus Usual Care

Chronic Obstructive Pulmonary Disease

United States
Bayer

Completed

A Study to Evaluate Changes in Nasal Airflow of Loratadine/Pseudoephedrine Tablet and Fluticasone Propionate Nasal Spray in Subjects Following Allergen Exposure

Rhinitis, Allergic

Canada
Forest Laboratories

Completed

Study To Assess Efficacy and Safety of Oglemilast in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States
Riphah International University

Completed

Icing and Airflow Stimulation in Obstructive Lung Diseases

Chronic Obstructive Pulmonary Disease

Pakistan
Poitiers University Hospital

Unknown

Comparison of Patient Work of Breathing and Tidal Volumes With High Flow Nasal Cannula Oxygen Therapy and NIV (Non-Invasive Ventilation) After Extubation in the ICU. (OVNI)

Extubation | Work of Breathing | ICU | Non-invasive Ventilation | Tidal Volume | Respiratory Effort | High-Flow Nasal Oxygen Therapy

France
The Christie NHS Foundation Trust
University of Manchester; Elekta Limited

Completed

Magnetic Resonance Imaging (MRI) for the Delineation of Organs At Risk (OAR) and Target Volumes in Lung Cancer Patients (MR-Lung)

Lung Cancer

United Kingdom
The Netherlands Cancer Institute

Completed

Irradiation of Large Lung Tumors or Two or More Lung Metastases Simultaneously (VOLUMES)

Lung Cancer | Metastatic Lung Cancer

Netherlands, United States, Canada, Germany
New York City Health and Hospitals Corporation

Unknown

Thermal Imaging as a Potential Diagnostic Tool of Nasal Airflow

Nasal Airway Obstruction

United States
GlaxoSmithKline

Completed

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GlaxoSmithkline (GSK) Biologicals' Investigational Vaccine GSK2838504A When Administered to Chronic Obstructive Pulmonary Disease (COPD) Patients With Persistent Airflow Obstruction.

Respiratory Disorders

Sweden, United Kingdom
Queen's University

Completed

Effects of N-acetylcysteine on Cardiorespiratory Control in COPD Patients With Mild-to-moderate Airflow Obstruction

Pulmonary Disease, Chronic Obstructive
University of Cadiz
European Regional Development Fund

Completed

Feel Breathe, Restriction Device Ventilatory Nasal (COPD) (BreatheCOPD)

Chronic Obstructive Pulmonary Disease

Spain
Sunovion Respiratory Development Inc.

Completed

Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [ie, Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered With an Electronic eFlow Nebulizer System in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease
Beijing Tongren Hospital

Unknown

The Effects of Nasal Airflow on Upper Airway Dilator Muscles During Sleep

Obstructive Sleep Apnea

China
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Conselho Nacional de...

Completed

Nasal and Oronasal Mask in Severe OSA Patients With Nasal Free Airflow of Obstruction

Obstructive Sleep Apnea of Newborn

Brazil
Karolinska Institutet

Completed

A Pilot Validation Study of Continuous CO2-based End-expiratory Lung Volume Measurements in Humans. (ELVIS)

Pulmonary Function | Ventilator Lung | Gas Exchange

Sweden
Sunovion Respiratory Development Inc.

Completed

Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [i.e., Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered Using an eFlow Nebulizer in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease
Universitätsklinikum Hamburg-Eppendorf

Unknown

Influence of Different PEEP Levels and Tidal Volumes on Regional Lung Function

Pulmonary Ventilation; Newborn, Abnormal

Germany
AstraZeneca

Completed

A Non-interventional Study to Investigate the Current Situation of Asthma-COPD Overlap Syndrome in Patients Over Age 40 With Persistent Airflow Limitation in China

Asthma-COPD Overlap Syndrome

China
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Asthma

Airway Inflammation | Severe, Refractory Asthma | Airflow Obstruction

United States
FluGen Inc
Accelovance

Completed

Intracutaneous Delivery of Varied Dose Volumes of Saline

Influenza

United States
GlaxoSmithKline

Completed

Investigation of Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy of Oral Danirixin in Symptomatic COPD Subjects With Mild to Moderate Airflow Limitation at Risk for Exacerbations

Pulmonary Disease, Chronic Obstructive

United States, Germany
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Pioglitazone Hydrochloride (Actos(Registered Trademark)) to Treat Asthma

Asthma | Airway Inflammation | Airflow Obstruction | Airway Hyperactivity

United States
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Positive Airway Pressure for the Treatment of Asthma

Asthma | Sleep Apnea

United States
AstraZeneca

Terminated

Comparison of Aclidinium Bromide and Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States
AstraZeneca

Completed

Safety and Tolerability of Aclidinium Bromide/Formoterol Fumarate Compared With Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
AstraZeneca

Completed

Efficacy, Safety and Tolerability of Two Fixed Dose Combinations of Aclidinium Bromide/Formoterol Fumarate, Aclidinium Bromide, Formoterol Fumarate and Placebo for 28-Weeks Treatment in Patients With Moderate to Severe, Stable Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Australia, Canada, New Zealand
Novartis Pharmaceuticals

Withdrawn

Safety and Efficacy of NVA237 as an add-on to Fixed Dose Combination LABA/ICS (GLOW8)

Chronic Obstructive Pulmonary Disease
AstraZeneca

Completed

Long-term Safety, Tolerability and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-35) (LAS-MD-35)

Chronic Obstructive Pulmonary Disease

United States, Canada
AstraZeneca

Completed

Efficacy, Safety and Tolerability of Aclidinium Bromide/Formoterol Fumarate Compared With Aclidinium Bromide and Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Australia, Canada, New Zealand
Ann & Robert H Lurie Children's Hospital of Chicago

Unknown

Early Detection and Management of Bronchiolitis Obliterans Syndrome Following Pediatric Hematopoietic Stem Cell Transplantation

Bronchiolitis Obliterans Syndrome

United States
AstraZeneca

Completed

Efficacy and Safety Study of Two Fixed-dose Combinations of Aclidinium Bromide With Formoterol Fumarate Compared With Aclidinium Bromide, Formoterol Fumarate and Placebo (LAC-MD-27)

Chronic Obstructive Pulmonary Disease

United States
Walter Reed National Military Medical Center

Completed

Airflow Perturbation Device (APD) for the Evaluation of Pulmonary and Sleep Disorders

Airway Obstruction
Portsmouth Hospitals NHS Trust
University of Oxford

Completed

Laminar Airflow in Severe Asthma for Exacerbation Reduction (LASER)

Asthma

United Kingdom
AstraZeneca

Completed

Pharmacokinetic, Safety and Tolerability Study of Aclidinium/Formoterol Fixed Dose Combination and Formoterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Invion, Inc.

Completed

Efficacy and Safety of Βeta-adrenoceptor Inverse Agonist and Biased Ligand, Nadolol, In Smoking Cessation of Patients With Chronic Cough With or Without Airflow Obstruction

Smoking Cessation

United States
AstraZeneca

Completed

Efficacy, Safety, and Tolerability of Aclidinium Bromide in the Treatment of Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-38) (LAS-MD-38)

Chronic Obstructive Pulmonary Disease

United States, Canada
AstraZeneca

Completed

Efficacy and Safety of Aclidinium Bromide for Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-33)

Chronic Obstructive Pulmonary Disease

United States, Canada
AstraZeneca

Completed

Long-term Extension Study of the Safety, Tolerability, and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-36)

Chronic Obstructive Pulmonary Disease

United States, Canada
Breathe Technologies, Inc.

Completed

Non-invasive Ventilation System in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) (PRIDE)

Pulmonary Disease, Chronic Obstructive | Chronic Obstructive Lung Disease | Chronic Obstructive Airway Disease | Airflow Obstruction, Chronic

United States
Breathe Technologies, Inc.

Completed

In-home Evaluation of a Noninvasive Open Ventilation System in Patients With Severe Respiratory Insufficiency

Pulmonary Disease, Chronic Obstructive | Chronic Obstructive Lung Disease | Chronic Obstructive Airway Disease | Airflow Obstruction, Chronic

United States
University of Chicago

Terminated

Observational Study of Blood Pressure Measurements and Continuous Dialysis

Shock | Critical Illness | Respiratory Failure | Kidney Failure

United States
Arbeitsgemeinschaft Nuklearmedizin und Strahlentherapie...

Unknown

Radiotherapy Planning Based on Positron Emission Tomography With Fluoro-deoxyglucose For Advanced NSCLC (PET-Plan)

Non-small Cell Lung Cancer

Germany
Universidade Federal de Pernambuco

Unknown

Efficacy of Pattern Respiratory PNF Associated Aerobic Training on Lung Volumes and 6MWT Test in Parkinson Individuals

Parkinson Disease

Brazil
Novartis Pharmaceuticals

Completed

Comparison of Long-term Safety of the Combination Product QVA149A Against Placebo and Standard of Care Treatment in Chronic Obstructive Pulmonary Disease Patients With Moderate to Severe Airflow Limitation

Chronic Obstructive Pulmonary Disease (COPD)

Colombia, India, Korea, Republic of, Poland, Croatia, Estonia, Hungary, United Kingdom, Israel, Latvia, Turkey, Argentina, Panama, Mexico, Russian Federation, Serbia, Slovenia

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