Search clinical trials for: empiric therapy

Total 51766 results

Fundación Pública Andaluza para la gestión de la...

Completed

Study to Reduce Duration of Antibiotic Therapy in Haematological Patients With Fever and Neutropenia (HOWLONG)

Febrile Neutropenia

Spain
Assistance Publique - Hôpitaux de Paris

Unknown

Therapeutic Trial Comparing Triple Therapy Guided by the PCR Detection of Clarithromycin Resistance vs Empiric Concomitant Quadruple Therapy for Helicobacter Pylori Infection (Hepysé)

H Pylori Eradication | H Pylori Infection Eradication | Antibiotics Therapeutic Strategies

France
Dr. Reddy's Laboratories Limited

Unknown

Levofloxacin as an Empirical Therapy in Patients With Complicated Urinary Tract Infections (Levolet-KZ16)

Urinary Tract Infection

Kazakhstan
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Genotypic Resistance Guided Therapy in Helicobacter Pylori Eradication

Self Efficacy

Taiwan
University Hospital, Lille

Completed

Fungal Biomarkers to Reduce Duration of Empirical Antifungal Therapy: a Randomized Comparative Study (STAFE) (STAFE)

Critical Illness | Fungal Infection

France
Merck Sharp & Dohme LLC
Mycoses Study Group

Terminated

Pilot Feasibility Study With Patients Who Are at High Risk For Developing Invasive Candidiasis in a Critical Care Setting (MK-0991-067)

Invasive Candidiasis
Merck Sharp & Dohme LLC

Completed

A 28 - 90 Days Study to Evaluate the Safety, Tolerability, and Efficacy of Caspofungin Injection as Empirical Therapy in Indian Adults With Persistent Fever and Neutropenia (0991-053)(COMPLETED)

Fungal Infection
Merck Sharp & Dohme LLC

Completed

MK0991 Versus Amphotericin B for Empirical Therapy in Febrile, Neutropenic Pediatric Patients (0991-044)

Neutropenia | Fever
Domonkos Trásy

Completed

Early Procalcitonin Kinetics During Empirical Antibiotic Therapy in Critically Ill Patients

Bacterial Infections

Hungary
University of Pittsburgh
Johns Hopkins University; Baylor College of Medicine; Beth Israel Medical Center and other collaborators

Withdrawn

Microbiology Testing With the Aim Of Directed Antimicrobial Therapy For CAP (NIHCAP)

Community-acquired Pneumonia

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Empiric Antibiotic Therapy for Ventilator-acquired Pneumonia With Gram-negative Bacilli in Intensive Care (TARGET-REA)

Ventilator-associated Pneumonia

France
Merck Sharp & Dohme LLC

Completed

Evaluate the Safety and Efficacy of Caspofungin Acetate as Empirical Therapy in Chinese Adults With Persistent Fever and Neutropenia (0991-055)

Fungal Infection
West China Hospital

Terminated

Treatment Method Research of Invasive Pulmonary Fungal Infection (4056)

IFI

China
Princess Margaret Hospital, Hong Kong
Medtronic

Withdrawn

Comparative Study to Examine Whether Echocardiography Performed During Cardiac Resynchronization Therapy Device Implantation Can Improve the Response Rate (E-OPT)

Heart Failure | Cardiac Resynchronization Therapy | Echocardiography

China
Fortis Hospital, India
Merck Sharp & Dohme LLC

Completed

Study to Evaluate the Clinical Outcome in High Risk Patients Who Received Empirical Antifungal Therapy

Antifungal Therapy

India
University of Roma La Sapienza

Unknown

Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis

Cirrhosis

Italy
Assistance Publique Hopitaux De Marseille

Completed

De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis

Severe Sepsis

France
Duke University
Pfizer

Completed

β-D-Glucan (BDG) Surveillance With Preemptive Anidulafungin vs. Standard Care for Invasive Candidiasis in Surgical Intensive Care Unit (SICU) Patients

Invasive Candidiasis

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Empiric Therapy of Mucopurulent Cervicitis (MPC)

Cervicitis | Vaginitis Bacterial

United States
Yonsei University

Completed

Micafungin Versus Intravenous Itraconazole as Empirical Antifungal Therapy for Febrile Neutropenic Patients With Hematological Diseases

Febrile Neutropenia | Hematological Diseases

Korea, Republic of
Domonkos Trásy

Completed

Increase in Procalcitonin Kinetics May be a Good Indicator of Starting Empirical Antibiotic Treatment in Critically Ill Patients

Bacterial Infection

Hungary
University of Washington
Centers for Disease Control and Prevention; Kenya Medical Research Institute

Completed

Empiric Therapy of Helminth Co-infection to Reduce HIV-1 Disease Progression (THE or PHE)

HIV Infections | Helminthiasis

Kenya
University of Aarhus

Completed

Empiric Versus Imaging Guided Left Ventricular Lead Placement in Cardiac Resynchronization Therapy (ImagingCRT)

Heart Failure

Denmark
Chinese PLA General Hospital

Completed

Piperacillin/Tazobactam for Empirical Therapy of Febrile Neutropenia

Neutropenia | Hematopoietic Stem Cell Transplantation | Febrile

China
Universidade Federal do Rio de Janeiro
Federal University of São Paulo

Terminated

Validation of an Index of Neutropenia (D-index) in Febrile Neutropenic Cancer Patients (Dindexval)

Invasive Fungal Infections | Invasive Aspergillosis | Invasive Fusariosis

Brazil
Lawson Health Research Institute
University of Western Ontario, Canada

Completed

Predictors of Failure of Empiric Outpatient Antibiotic Therapy in Emergency Department Patients With Uncomplicated Cellulitis.

Uncomplicated Outpatient Cellulitis

Canada
Janssen Korea, Ltd., Korea

Completed

A Study of Empirical Antifungal Therapy With Itraconazole

Neutropenia
Assistance Publique - Hôpitaux de Paris

Completed

Impact of Imipenem With Amikacin Pharmacokinetic and Pharmacodynamic (IMPACT)

Ventilator Associated Pneumonia

France
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

SWOG-S9635 Fluorouracil Plus Ethynyluracil in Advanced Colorectal Cancer Not Responded to Fluorouracil

Colorectal Cancer

United States
Brigham and Women's Hospital
Astellas Pharma US, Inc.

Completed

Caspofungin or Micafungin as Empiric Antifungal Therapy for Persistent Fever and Neutropenia

Febrile Neutropenia

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized, Open Label, Comparative, Multicenter Trial of Voriconazole Vs. AmBisome for Empirical Antifungal Therapy in Immunocompromised Patients With Persistent Fever and Neutropenia

Neutropenia

United States
University of Tartu
Estonian Science Foundation; European Society for Paediatric Infectious Diseases

Completed

Management of Early Onset Neonatal Septicaemia: Selection of Optimal Antibacterial Regimen for Empiric Treatment

Early Onset Neonatal Sepsis

Estonia
National Cancer Institute (NCI)

Completed

Phase I Study of the Safety, Tolerance, and Pharmacokinetics of FK463 in Immunocompromised Children With Fever and Neutropenia

Mycoses | Neutropenia | Fever

United States
Canadian Critical Care Trials Group
The Physicians' Services Incorporated Foundation

Completed

Pilot Study of the Utility of Empiric Antibiotic Therapy for Suspected ICU-Acquired Infection

Pneumonia | Systemic Inflammatory Response Syndrome | Critical Illness | Nosocomial Infection | Pyrexia

Canada
Assistance Publique - Hôpitaux de Paris

Terminated

Comparison of 2 Antifungal Treatment (Empirical Versus Pre-Empirical) Strategies in Prolonged Neutropenia

Malignant Hemopathy | Duration of Neutropenia Following Chemotherapy > 10 Days

France
Jonsson Comprehensive Cancer Center

Not yet recruiting

PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma

Glioblastoma

United States
Peking University First Hospital

Recruiting

Fractional Flow Reserve-guided Stenting Versus Medical Therapy in Atherosclerosis Renal Artery Stenosis (FAIR)

Renal Artery Stenosis Atherosclerotic | Secondary Hypertension Renal Arterial

China
Nanfang Hospital, Southern Medical University

Recruiting

Research on the Mechanisms of Treatment Non-response in Inflammatory Bowel Disease Based on Multi-omics Technology

Inflammatory Bowel Diseases

China
Fudan University

Not yet recruiting

The Efficacy and Safety of Cadonilimab (AK104) as Induction and Consolidation Therapy for Locally Advanced/Unresectable NSCLC Patients Receiving Concurrent Chemoradiotherapy

NSCLC | Locally Advanced Lung Carcinoma

China
BioNTech SE

Not yet recruiting

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

Triple Negative Breast Cancer | Locally Advanced Breast Cancer
BioNTech SE

Not yet recruiting

Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy

Small-cell Lung Cancer | Extensive-stage Small-cell Lung Cancer
Gulf Medical University

Recruiting

Manual Therapy of Spine With Postural Correction Exercise Compared With Conventional Therapy in Patients With Adhesive Capsulitis - A Randomised Clinical Trial

Adhesive Capsulitis of Shoulder

United Arab Emirates
Colorado State University

Not yet recruiting

Occupational Therapy Led Social Prescription for People With Parkinson Disease

Parkinson Disease
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Evaluation of Respiratory Mechanics in Supine and PARK-bench Positions (SPARK) (SPARK)

Ventilator-Induced Lung Injury | Ventilation Therapy; Complications

Italy
Shanghai Zhongshan Hospital

Recruiting

Effects of Growth Hormone Therapy on Metabolic Function in Fatty Liver Post-Pituitary Adenoma Surgery

Growth Hormone Treatment

China
The University of Hong Kong

Not yet recruiting

Evaluation of Efficacy and Safety of Enhanced External Counter-pulsation on Patients With Atopic Dermatitis and Inflammatory Skin Disease Requiring Wet Wrap Therapy

Atopic Dermatitis | Inflammatory Skin Disease
Centre Integre Universitaire de Sante et Services...

Not yet recruiting

Cannabidiol After Multi-Trauma for Pain and Opioid Therapy (CAM-POT)

Fracture
Medstar Health Research Institute
Medtronic

Recruiting

Optimal Pacing Rate for Cardiac Resynchronization Therapy (OPT-RATE AF)

Atrial Fibrillation, Persistent

United States
Shahirose Sadrudin Premji
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

A Chinese Version of the Thinking Health Program for East Asian Pregnant Immigrant People in Canada

Perinatal Depression

Canada
Brown University
The Miriam Hospital

Not yet recruiting

Musical Playlist of the Grief Journey

Music Therapy | Bereavement

3

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