Search clinical trials for: personalized neoantigen cancer vaccine

Total 96050 results

Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Combination With Standard First-line Treatment in Subjects With Advanced Digestive System Neoplasms

Digestive System Neoplasms

China
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Subjects With Resected Digestive System Neoplasms

Digestive System Neoplasms

China
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen Alone in Subjects With Advanced Digestive System Neoplasms

Digestive System Neoplasms

China
Stemirna Therapeutics
Peking University Cancer Hospital & Institute

Not yet recruiting

Clinical Study of mRNA Vaccine in Patients With Advanced Malignant Solid Tumors

Advanced Malignant Solid Tumors
jianming xu
NeoCura

Recruiting

A Safety and Efficacy Study of XH001 Combined With Sintilimab Injection in Advanced Solid Tumors

Solid Tumor

China
Ruijin Hospital
Shanghai Xinpu BioTechnology Company Limited

Recruiting

Personalized Tumor Vaccines and Pembrolizumab in Patients With Advanced Solid Tumors

Advanced Solid Tumor

China
Cancer Institute and Hospital, Chinese Academy...

Recruiting

LK101 Combined With PD-1 or PD-L1 Monoclonal Antibody in the Treatment of Lung Cancer

Advanced Lung Carcinoma

China
National Health Research Institutes, Taiwan
National Cheng-Kung University Hospital

Recruiting

Neoantigen Derived DCs as Cancer Treatment

Solid Tumor | Refractory Tumor

Taiwan
Washington University School of Medicine
Incyte Corporation; PapiVax Biotech, Inc.

Recruiting

Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Unmethylated Glioblastoma

United States
SLK Kliniken Heilbronn GmbH

Recruiting

IVAC-RCC-001: A Personalized Neoantigen Vaccine as Add-on to Standard of Care Checkpoint Inhibitor in Advanced/Metastatic RCC Patients

Advanced Renal Cell Carcinoma

Germany
YueJuan Cheng
NeoCura

Recruiting

Safety and Efficacy of Personalized Neoantigen Vaccine in Advanced Solid Tumors

Solid Tumor

China
Sichuan University

Not yet recruiting

A Translational Study of Tumor Antigen-pulsed DC Vaccine for ESCC

Esophageal Squamous Cell Carcinoma

China
Second Affiliated Hospital, School of Medicine,...
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Neoantigen Vaccine in Esophagus Cancer Patients Following Neoadjuvant Therapy and Surgical Resection

Resectable Esophageal Cancer

China
West China Second University Hospital

Not yet recruiting

Dendritic Cell Vaccination With Standard Postoperative Chemotherapy for the Treatment of Adult Ovarian Cancer

Recurrent Ovarian Cancer

China
Centre Hospitalier Universitaire Vaudois

Recruiting

Personalized DC Vaccines in Non Small Cell Lung Cancer

Non-small Cell Lung Cancer

Switzerland
Washington University School of Medicine
National Cancer Institute (NCI); Leidos; UNICO Foundation

Recruiting

Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
National Cancer Institute (NCI)

Recruiting

Cancer Preventive Vaccine Nous-209 for Lynch Syndrome Patients

Lynch Syndrome

United States, Puerto Rico
zeinab ahmed yousif hasan ashour

Recruiting

Personalized Cancer Vaccine in Egyptian Cancer Patients (PROVE)

Hepatocellular Carcinoma

Egypt
Sidney Kimmel Comprehensive Cancer Center at Johns...
Stand Up To Cancer

Recruiting

Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer

Pancreatic Cancer | High Risk Cancer

United States
Ashutosh Kumar Tewari

Recruiting

The Safety and Tolerability of PGV001-based Personalized Multi-peptide Vaccines in the Adjuvant Setting. (PGV-Prostate)

Prostate Cancer

United States
Frame Pharmaceuticals B.V.
University Medical Center Groningen; Erasmus Medical Center; The Netherlands... and other collaborators

Not yet recruiting

FRAME-001 Personalized Vaccine in NSCLC

Non Small Cell Lung Cancer

Netherlands
Xuanwu Hospital, Beijing
Beijing Neoantigen Biotechnology Company

Recruiting

Personalized Vaccine for Patients With Recurrent Malignant Glioma

Malignant Glioma | Recurrent Glioma

China
National Cancer Centre, Singapore
Bristol-Myers Squibb

Recruiting

Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC

Hepatocellular Carcinoma | Colorectal Cancer | Liver Metastases | Colorectal Carcinoma | Hepatocellular Cancer

Singapore
Centre Hospitalier Universitaire Vaudois

Recruiting

Personalized Vaccine With SOC Chemo Followed by Nivo in Pancreatic Cancer

Pancreatic Adenocarcinoma

Switzerland
Sun Yat-sen University
Tianjin Hengjia Biotechnology Development co., LTD

Recruiting

Phase I Study of Individualized Neoantigen Peptides in the Treatment of EGFR Mutant Non-small Cell Lung Cancer

Non Small Cell Lung Cancer

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb; National Cancer Institute (NCI); Fibrolamellar Cancer Foundation

Recruiting

DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma

Fibrolamellar Hepatocellular Carcinoma (FLC)

United States
Sichuan University

Recruiting

Personalized DC Vaccine for Postoperative Cancer

Hepatocellular Carcinoma | Gastric Cancer | Non-Small-Cell Lung Cancer | Colon Rectal Cancer

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb; National Cancer Institute (NCI); National Institutes of...

Recruiting

Pooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected Mismatch Repair Protein (MMR-p) Colorectal and Pancreatic Cancer

Colorectal Cancer | Pancreatic Cancer

United States
Washington University School of Medicine
Children's Discovery Institute

Not yet recruiting

Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Brain Tumors

Pediatric Recurrent Brain Tumor

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Individualized Vaccine to Nab-Paclitaxel, Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Invasive Breast Carcinoma | Metastatic Triple-Negative Breast Carcinoma

United States
Anda Biopharmaceutical Development (Shenzhen) Co...

Recruiting

Clinical Trial on Personalized Neoantigen Vaccine for Pancreatic Tumor

Pancreatic Tumor

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Personalized Peptide Vaccine in Treating Patients With Advanced Pancreatic Cancer or Colorectal Cancer

Stage IV Pancreatic Cancer AJCC v6 and v7 | Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Pancreatic Ductal Adenocarcinoma

United States
Janssen Research & Development, LLC
Bristol-Myers Squibb

Active, not recruiting

A Study of VAC85135, a Neoantigen Vaccine Regimen, Concurrently Administered With Ipilimumab for the Treatment of Myeloproliferative Neoplasms

Myeloproliferative Neoplasms

United States, United Kingdom
Washington University School of Medicine
National Cancer Institute (NCI); National Institutes of Health (NIH); MedImmune...

Terminated

Neoantigen DNA Vaccine Alone vs. Neoantigen DNA Vaccine Plus Durvalumab in Triple Negative Breast Cancer Patients Following Standard of Care Therapy

Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | TNBC - Triple-Negative Breast Cancer | Triple-negative Breast Carcinoma

United States
University Hospital Tuebingen

Available

Personalized Multi-peptide Vaccination in Combination With the TLR1/2 Ligand XS15 in Cancer Patients (InHeVac01)

Cancer
M.D. Anderson Cancer Center

Active, not recruiting

Personalized Vaccine in Treating Patients With Smoldering Multiple Myeloma

Smoldering Plasma Cell Myeloma

United States
Genentech, Inc.
BioNTech SE

Active, not recruiting

A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

Melanoma | Head and Neck Cancer | Colorectal Cancer | Non-Small Cell Lung Cancer | Bladder Cancer | Triple Negative Breast Cancer | Renal Cancer | Other Solid Cancers

United States, Belgium, Sweden, Germany, Canada, Spain, United Kingdom, Netherlands
Geneos Therapeutics

Active, not recruiting

GNOS-PV02 Personalized Neoantigen Vaccine, INO-9012 and Pembrolizumab in Subjects With Advanced HCC

HCC

United States, New Zealand
Albert Einstein College of Medicine
NovoCure Ltd.

Active, not recruiting

Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastoma

Glioblastoma

United States
Washington University School of Medicine
The Foundation for Barnes-Jewish Hospital; Geneos Therapeutics

Active, not recruiting

Neoantigen-based Personalized DNA Vaccine in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Glioblastoma

United States
Capital Medical University
Duke University

Withdrawn

Personalized Vaccine Generated by Autologous Dendritic Cells Pulsed With Autologous Whole Tumor Cell Lysate Treat Advanced Solid Tumor Patients With High Tumor Mutation Burden

Metastatic Cancer | Advanced Cancer

China
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Active, not recruiting

Neoantigen Vaccine Plus Locally Administered Ipilimumab and Systemic Nivolumab in Advanced Melanoma

Melanoma

United States
Memorial Sloan Kettering Cancer Center
Genentech, Inc.

Active, not recruiting

Study of Personalized Tumor Vaccines (PCVs) and a PD-L1 Blocker in Patients With Pancreatic Cancer That Can be Treated With Surgery

Pancreatic Cancer

United States
Patrick Ott, MD, PhD
Bristol-Myers Squibb; Oncovir, Inc.

Active, not recruiting

NeoVax Plus Ipilimumab in Renal Cell Carcinoma

Kidney Cancer

United States
Craig L Slingluff, Jr
Celldex Therapeutics

Active, not recruiting

Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists In Patients With Melanoma (Including Ocular Melanoma) (Mel66)

Melanoma | Ocular Melanoma | Uveal Melanoma

United States
Hubro Therapeutics AS
Quotient Sciences

Completed

Safety and Immune Response to FMPV-1

Colorectal Cancer

United Kingdom
University of Maryland, College Park

Completed

A Chatbot Intervention for Reducing HPV Vaccine Hesitancy

Cervical Cancer | Anal Cancer | Penile Cancer

United States
Washington University School of Medicine
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

Neoantigen Peptide Vaccine Strategy in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
NantBioScience, Inc.

Active, not recruiting

QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers.

Melanoma | Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Liver Cancer

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Incyte Corporation

Withdrawn

Neoantigen-Targeted Vaccine Combined With Anti-PD-1 Antibody for Patients With Stage IV MMR-p Colon and Pancreatic Ductal Cancer

Colorectal Cancer Metastatic | Pancreatic Cancer Metastatic

United States

Search clinical trials for: personalized neoantigen cancer vaccine

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