Search clinical trials for: Randomized study

Total 127119 results

Ortho Pharmaceuticals

Completed

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of Subcutaneous Doses of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

HIV Infections | Cytopenias

United States
Fairview University Medical Center

Completed

Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia

Myelodysplastic Syndromes | Leukemia, Lymphocytic, Acute | Fanconi's Anemia | Leukemia, Nonlymphocytic, Acute

United States
Genentech, Inc.

Completed

A Phase I Study of the Safety and Immunogenicity of Rgp 120/HIV-1IIIB Vaccine in HIV-1 Seropositive Adult Volunteers

HIV Infections

United States
Newport Pharmaceuticals International

Completed

A Double-Blind Placebo Controlled Study To Determine the Optimal Immunopharmacological Dose Level of Isoprinosine in Immunodepressed Volunteers

HIV Infections

United States
AJI Pharma USA

Completed

Phase I/II Study of the Tolerance and Efficacy of Combined Use of Didanosine (2',3'-Dideoxyinosine; ddI) and Lentinan in HIV-Positive Patients

HIV Infections

United States
Hoechst Marion Roussel

Completed

A Study of the Safety and Efficacy of Chronically Administered MDL 28,574A in the Treatment of HIV-Infected Patients

HIV Infections

United States
Ligand Pharmaceuticals

Completed

A Study of Targretin Capsules in Patients With AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Univax Biologics Inc

Completed

A Randomized, Multicenter, Double-Blind, Parallel-Group, Placebo-Controlled Trial of the Efficacy and Safety of Bovine Anti-Cryptosporidium Immunoglobulin (BACI) in the Treatment of Cryptosporidium Enteritis in AIDS Patients

HIV Infections | Cryptosporidiosis

United States
Pharmacia

Completed

A Study of Rifabutin, Used Alone or With Ethambutol in the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in Patients With AIDS

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
National Center for Research Resources (NCRR)
Baylor College of Medicine

Unknown

Study of Treatment and Metabolism in Patients With Urea Cycle Disorders

Amino Acid Metabolism, Inborn Errors

United States
Glaxo Wellcome

Completed

A Study of Retrovir in the Prevention of HIV Infection in Health Care Workers Accidentally Exposed to the Virus

HIV Infections

United States
Mylan Laboratories

Completed

A Phase II/III Study of Cysteamine (Mercaptoethylamine) and Zidovudine for the Treatment of HIV Disease

HIV Infections

United States
University of California, San Francisco

Completed

A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I Study of Tin Mesoporphyrin in Patients on Long Term Heme Therapy for Prevention of Acute Attacks of Porphyria

Porphyria
Eunice Kennedy Shriver National Institute of Child...
University of Washington

Unknown

Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders

Wiskott-Aldrich Syndrome | Leukocyte Adhesion Deficiency Syndrome | X-Linked Agammaglobulinemia | X-Linked Hyper IgM Syndrome

United States
National Center for Research Resources (NCRR)
Children's Hospital Colorado

Unknown

Phase I Study of Colchicine Therapy in Childhood Hepatic Cirrhosis

Liver Cirrhosis | Cirrhosis
National Center for Research Resources (NCRR)
Genentech, Inc.

Completed

Growth Hormone Use in Cystic Fibrosis - a Multicenter Study

Cystic Fibrosis

United States
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients With Aplastic Anemia

Aplastic Anemia

United States
National Institute on Drug Abuse (NIDA)
University of Texas

Completed

Phase II Double-Blind, Placebo-Controlled Study of the Reinforcing Effects of Alprazolam in Patients With Anxiety

Panic Disorder | Anxiety Disorder

United States
Glaxo Wellcome

Completed

A Study of the Safety and Effectiveness of Combination Anti-HIV Therapy in HIV-Infected Adults

HIV Infections

United States
National Center for Research Resources (NCRR)
Stanford University

Completed

Pilot Study of Enalapril and Renal Function in Patients With IgA Nephropathy

IGA Glomerulonephritis
Triangle Pharmaceuticals

Unknown

A Safety Study to Evaluate 12 Weeks of Treatment with Clevudine in Patients Infected with Hepatitis B Virus.

Hepatitis B

United States, Canada, China, France, Singapore
Argus Pharmaceuticals

Completed

A Study of Nystatin in HIV-Infected Patients

HIV Infections

United States
The Avicena Group

Unknown

Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS)

United States
Eunice Kennedy Shriver National Institute of Child...
Johns Hopkins University

Completed

Study of the Pathogenesis of Rett Syndrome

Rett Syndrome
Chugai Pharma USA

Completed

A Blinded Study Conducted at Multiple Centers Evaluating Various Doses of an Investigational Agent (BO-653) Against Placebo, for Safety and Effectiveness in Preventing Post-Angioplasty Blood Vessel Re-Closure (Restenosis) in Stented Vessels.

Atherosclerosis | Coronary Restenosis | Graft Occlusion, Vascular

United States
National Eye Institute (NEI)

Unknown

The Early Treatment for Retinopathy of Prematurity Study (ETROP)

Retinopathy of Prematurity

United States
National Eye Institute (NEI)

Unknown

The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study

Myopia

United States
Hoffmann-La Roche

Completed

A Study of Saquinavir and Zalcitabine, Used Alone and Together, in the Treatment of Advanced HIV Infection in Patients Who Stopped Taking or Who Cannot Take Zidovudine

HIV Infections

United States, Puerto Rico, Canada
Gilead Sciences

Completed

Phase I Study of the Safety, Tolerance, and Pharmacokinetics of 9-[2-(Bispivaloyloxymethyl)Phosphonylmethoxyethyl]Adenine (Bis-POM PMEA; Adefovir Dipivoxil) in HIV-Infected Patients

HIV Infections

United States
Shaman Pharmaceuticals

Completed

Double-Blind Placebo-Controlled Study Comparing the Combination of 15% SP-303 Gel With Acyclovir Versus Acyclovir Alone for the Treatment of Recurrent Herpes Simplex Virus (HSV) Infections in Subjects With Acquired Immunodeficiency Syndrome (AIDS)

HIV Infections | Herpes Simplex

United States, Puerto Rico
National Center for Research Resources (NCRR)
Baylor College of Medicine

Completed

Phase IV Study of Chronic Infusional Epoprostenol for Severe Primary Pulmonary Hypertension

Hypertension, Pulmonary
National Center for Research Resources (NCRR)
University of Texas

Completed

Study of Nutritional Factors in Porphyria

Porphyria
National Center for Research Resources (NCRR)

Suspended

A Multi-Centered Study of the Long-Term Effect of Salmeterol and Albuterol in Cystic Fibrosis

Cystic Fibrosis

United States
University of Minnesota

Completed

Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia

Fanconi's Anemia

United States
National Center for Research Resources (NCRR)
Duke University

Unknown

A Safety and Feasibility Study of Active Immunotherapy in Patients With Metastatic Prostate Carcinoma Using Autologous Dendritic Cells Pulsed With Antigen Encoded in Amplified Autologous Tumor RNA

Prostate Cancer

United States
National Center for Research Resources (NCRR)
Crohn's and Colitis Foundation

Completed

A Pharmacokinetic Study to Determine the Oral Bioavailability of Methotrexate in Patients With Inflammatory Bowel Disease

Inflammatory Bowel Disease

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I/II Study of High-Dose Acyclovir for Central Nervous System or Disseminated Neonatal Herpes Simplex Virus Infection

Herpes Simplex
National Center for Research Resources (NCRR)
Johns Hopkins University

Completed

Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders

Amino Acid Metabolism, Inborn Errors
National Eye Institute (NEI)

Completed

Diabetic Retinopathy Vitrectomy Study (DRVS)

Diabetic Retinopathy | Vitreous Hemorrhage | Retinal Detachment
National Eye Institute (NEI)

Unknown

Randomized Trials of Vitamin Supplements and Eye Disease

Macular Degeneration | Cataract
National Institute of Allergy and Infectious Diseases...
Janssen Pharmaceuticals

Completed

A Study of Letrazuril in the Treatment of AIDS-Related Diarrhea

HIV Infections | Cryptosporidiosis

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

A Third-Party Blinded, Placebo Controlled Comparative Study of AS-101 Administered Intravenously in HIV Positive Patients With Advanced Disease

HIV Infections

Brazil
Ionis Pharmaceuticals, Inc.

Completed

A Randomized Comparison of Intravitreal ISIS 2922 Plus Ganciclovir Versus Ganciclovir as Treatment for Patients With Cytomegalovirus Retinitis ( CMVR )

HIV Infections | Cytomegalovirus Retinitis

United States
Gilead Sciences

Completed

An Open-Label Study of the Safety and Efficacy of Cidofovir for the Treatment of Relapsing Cytomegalovirus Retinitis in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
Hoechst Marion Roussel

Completed

A Study of MDL 28,574A in HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Rochester

Completed

Pilot Compassionate Use Study of Thioctic Acid Treatment in Mitochondrial Myopathy

Mitochondrial Myopathy
National Center for Research Resources (NCRR)
Icahn School of Medicine at Mount Sinai

Completed

Diagnostic and Screening Study of Genetic Disorders

Metabolism, Inborn Errors | Leukodystrophy, Globoid Cell | Tay-Sachs Disease | Porphyria, Erythropoietic

United States
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Ohio...

Completed

Study of Genetic Anomalies of Complement Related Proteins in Patients With IgA Glomerulonephritis

IGA Glomerulonephritis

United States
Glaxo Wellcome

Completed

A Study of Amprenavir in HIV-Infected Patients

HIV Infections

United States

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