Search clinical trials for: DNA Damage Repair

Total 13542 results

Hoffmann-La Roche

Completed

Open Label Ganciclovir Therapy for Sight- or Life-Threatening Cytomegalovirus Disease in the Immunocompromised Patient

HIV Infections | Cytomegalovirus Infections | Cytomegalovirus Retinitis

United States
Sequus Pharmaceuticals

Completed

Randomized, Comparative Trial of DOX-SL (Stealth Liposomal Doxorubicin Hydrochloride) Versus Bleomycin and Vincristine in the Treatment of AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Nexstar Pharmaceuticals

Completed

A Randomized Phase III Clinical Trial of Daunoxome Versus Combination Chemotherapy With Adriamycin/Bleomycin/Vincristine (ABV) in the Treatment of HIV-Associated Kaposi's Sarcoma.

HIV Infections | Sarcoma, Kaposi

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Magnesium Sulfate to Prevent Brain Injury in Premature Infants

Cerebral Palsy | Brain Injuries

United States
Anderson Clinical Research
Ligand Pharmaceuticals

Completed

A Study of ALRT 1057 Topical Gel in Patients With AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi
Astra USA

Completed

A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
National Institute of Neurological Disorders and...
Seattle Children's Hospital

Unknown

Phase II Randomized Study of Selective Dorsal Rhizotomy and Physiotherapy Vs Physiotherapy Alone for Spastic Diplegia

Spastic Diplegia
Sequus Pharmaceuticals

Unknown

A Comparison of DOX-SL Versus Adriamycin Plus Bleomycin Plus Vincristine in the Treatment of Severe AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Hoffmann-La Roche

Completed

A Study of the Safety and Tolerance of Long-Term Therapy With Intravenous Cytovene (Ganciclovir Sodium) for Cytomegalovirus Retinitis in Persons With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Ionis Pharmaceuticals, Inc.

Completed

A Study of ISIS 2922 in the Treatment of Advanced Cytomegalovirus Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Glaxo Wellcome

Completed

A Comparison of 882C87 Versus Acyclovir in the Treatment of Herpes Zoster in Patients With Weakened Immune Systems

HIV Infections | Chickenpox

United States
Gilead Sciences
Anderson Clinical Research

Unknown

A Study of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis
Roche Global Development

Completed

An Open Label Evaluation of the Safety and Pharmacokinetics of Ganciclovir in Children

HIV Infections | Cytomegalovirus Retinitis

United States
Sandoz

Completed

A Randomized, Phase I/II Trial to Assess the Safety and Antiviral Effects of Escalating Doses of A Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Viremia and/or Viruria

HIV Infections | Cytomegalovirus Infections

United States
Astra USA

Unknown

A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir

HIV Infections | Cytomegalovirus Retinitis

United States
Daiichi Pharmaceuticals

Completed

A Study of Tecogalan Sodium

HIV Infections | Sarcoma, Kaposi

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase III Randomized, Controlled Study of Ganciclovir for Symptomatic Congenital Cytomegalovirus Infection

Cytomegalovirus Infections
Hoffmann-La Roche

Completed

Ganciclovir: Compassionate Use in Patients With Serious or Life-Threatening Cytomegalovirus Infections

HIV Infections | Cytomegalovirus Infections

United States
Hoffmann-La Roche

Completed

A Multiple Dose Crossover Pharmacokinetics Study to Evaluate the Effects of Food on the Absorption of Oral Ganciclovir

HIV Infections | Cytomegalovirus Infections

United States
Hoffmann-La Roche

Completed

A Randomized Study Comparing the Safety and Efficacy of Two Regimens of Oral Ganciclovir to Intravenous Ganciclovir Maintenance Therapy for Cytomegalovirus Retinitis in People With AIDS Who Have Received Prior Ganciclovir Therapy

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Roche Global Development

Completed

A Study of Two Forms of Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Hoffmann-La Roche

Completed

A Study of Valganciclovir in the Treatment of Cytomegalovirus (CMV) Retinitis in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
University of Miami

Completed

A Pilot Study of the Efficacy of Recombinant Alpha Interferon (IFN-A2b) and Zidovudine (AZT) in the Treatment of Progressive Multifocal Leukoencephalopathy (PML) Complicating HIV-1 Infection

HIV Infections | Leukoencephalopathy, Progressive Multifocal

United States
Hoffmann-La Roche

Completed

A Phase I Pharmacokinetic Study in HIV-Positive Subjects of Oral Ganciclovir and Concomitant Antiretroviral Zidovudine and Didanosine

HIV Infections | Cytomegalovirus Infections

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase III Randomized, Placebo-Controlled Study of Acyclovir Oral Suspension for Neonatal Herpes Simplex Virus Infection Limited to the Skin, Eyes, and Mouth

Herpes Simplex
Otsuka America Pharmaceutical

Completed

A Pilot Study of OPC-8212 (Vesnarinone) in Persons With AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Hoffmann-La Roche

Completed

A Randomized, Double-Blind Study of the Efficacy and Safety of Oral Ganciclovir for the Prevention of CMV Disease in People Infected With the Human Immunodeficiency Virus

HIV Infections | Cytomegalovirus Infections

United States
Ionis Pharmaceuticals, Inc.

Completed

A Comparison of ISIS 2922 Used Immediately or Later in Patients With Cytomegalovirus (CMV) of the Eyes

HIV Infections | Cytomegalovirus Retinitis

United States
Astra USA

Completed

A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium)

HIV Infections | Cytomegalovirus Retinitis

United States
Astra USA

Completed

The Pilot Study of Foscarnet Cream in the Treatment of Mucocutaneous Herpes Simplex Virus Infections in Immunocompromised Patients Unresponsive to Acyclovir Treatment

HIV Infections | Herpes Simplex

United States
Astra USA

Completed

An Open, Multicenter Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies

HIV Infections | Herpes Simplex

United States
National Center for Research Resources (NCRR)
University of Alabama at Birmingham

Unknown

Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous System

Herpes Simplex

United States, Canada
Astra USA

Completed

Safety and Efficacy of Intravenous Magnesium Sulfate in Modulating Changes in Symptoms and Divalent Cation Levels Associated With Foscavir Therapy: A Phase IV Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Pilot Study

HIV Infections | Hypocalcemia | Cytomegalovirus Infections

United States
National Center for Research Resources (NCRR)
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects

Heart Defects, Congenital | Tetralogy of Fallot | Pulmonary Valve Stenosis | Hypoparathyroidism | Pulmonary Atresia | Conotruncal Cardiac Defects
Sequus Pharmaceuticals

Completed

Use of Stealth Liposomal Doxorubicin HCl ( DOX-SL ) in the Treatment of Moderate to Severe AIDS-Related Kaposi's Sarcoma.

HIV Infections | Sarcoma, Kaposi

United States
SUGEN

Completed

SU5416 in Patients With AIDS-Related Kaposi's Sarcoma Who Have Not Responded to Treatment

HIV Infections | Sarcoma, Kaposi

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I/II Study of Human Anti-Cytomegalovirus (CMV) Monoclonal Antibody MSL-109 in Newborns With Symptomatic Congenital CMV Infection Without Central Nervous System Disease

Cytomegalovirus Infections
Daiichi Pharmaceuticals

Completed

A Phase I Trial of Tecogalan Sodium (DS-4152) Administered as an Infusion Every 21 Days

HIV Infections | Sarcoma, Kaposi

United States
DEKK-TEC, Inc.

Completed

Topical Use of 4,4'-Dihydroxybenzophenone-2,4-Dinitrophenylhydrazone (A-007) in the Treatment of Advanced Malignancies Including Kaposi's Sarcoma and Lymphoproliferative Disorders

HIV Infections | Lymphoproliferative Disorders | Sarcoma, Kaposi

United States
SmithKline Beecham

Completed

Safety and Effectiveness of Topotecan HCl to Treat HIV-Infected Patients With AIDS-Related Progressive Multifocal Leukoencephalopathy (PML)

HIV Infections | Leukoencephalopathy, Progressive Multifocal

United States
Hoffmann-La Roche

Completed

A Randomized Controlled Study of the Efficacy and Safety of Maintenance Treatment With Oral Ganciclovir for Newly Diagnosed Cytomegalovirus Retinitis in People With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
National Institute of Allergy and Infectious Diseases...

Completed

A Study of HIV and Cytomegalovirus (CMV) in HIV-Infected Patients

HIV Infections | Cytomegalovirus Infections

United States
Glaxo Wellcome

Unknown

A Study of Valacyclovir as Treatment for Genital Herpes Simplex Virus in HIV-Infected Patients

HIV Infections | Herpes Simplex | Herpes Genitalis

United States, Canada
Glaxo Wellcome

Completed

Treatment and Suppression of Hairy Leukoplakia in ARC Patients With Oral Acyclovir (ACV)

HIV Infections | Leukoplakia, Hairy

United States
Astra USA

Completed

An Open Study of Foscarnet Treatment First Episode CMV-Retinitis in AIDS Patients

HIV Infections | Cytomegalovirus Retinitis

United States
National Center for Research Resources (NCRR)
Johns Hopkins University; National Institute of Neurological Disorders and...

Completed

Phase III Randomized Controlled Study of Morphine and Nortriptyline in the Management of Postherpetic Neuralgia

Pain | Herpes Zoster
Clinical Solutions

Completed

Photodynamic Therapy Clinical Trial For Cutaneous AIDS-Related Kaposi's Sarcoma Study Summary.

HIV Infections | Sarcoma, Kaposi

United States
Agouron Pharmaceuticals

Completed

A Pilot, Open-Label, Phase II, Randomized Study to Determine the Effects of Viracept on the Outcome of Cutaneous and Mucosal KS in AIDS Patients With CD4 <= 500 Cells/mm3

HIV Infections | Sarcoma, Kaposi

United States
Chiron Corporation

Completed

A Phase I Study of the Safety of Proleukin (Aldesleukin) in Combination With Ganciclovir and Antiretroviral Therapy in HIV Seropositive Patients With Cytomegalovirus (CMV) Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Glaxo Wellcome

Completed

A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients

HIV Infections | Herpes Simplex

United States

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