Clinical Trials Sponsored by Bernhard Nocht Institute for Tropical Medicine

Total 174 results

Foundation for Innovative New Diagnostics, Switzerland
London School of Hygiene and Tropical Medicine; Academisch Medisch Centrum... and other collaborators

Completed

Evaluation of Antibody Detection Tests for Visceral Leishmaniasis Diagnosis in Eastern Africa (VL-DX-EAFR)

Leishmaniasis, Visceral

Ethiopia, Kenya
National Institute for Medical Research, Tanzania
London School of Hygiene and Tropical Medicine; Rigshospitalet, Denmark; University... and other collaborators

Active, not recruiting

Diabetes Mellitus and HIV Study in Mwanza (CICADA)

Diabetes Mellitus | HIV/AIDS

Tanzania
King's College London
London School of Hygiene and Tropical Medicine; Guy's and St Thomas' NHS Foundation... and other collaborators

Completed

Study of Efficacy and Safety of Percutaneous Coronary Intervention to Improve Survival in Heart Failure (REVIVED-BCIS2)

Ischemic Cardiomyopathy

United Kingdom
Drugs for Neglected Diseases
Institute of Tropical Medicine, Belgium; Institut National de Recherche Biomédicale... and other collaborators

Not yet recruiting

Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT) (STROgHAT)

Human African Trypanosomiasis
Institute of Tropical Medicine, Belgium
University Hospital Tuebingen; Mbarara University of Science and Technology; Liverpool... and other collaborators

Completed

Evaluation of 4 Artemisinin-based Combinations for Treating Uncomplicated Malaria in African Children

Fever | Malaria

Burkina Faso, Gabon, Mozambique, Nigeria, Rwanda, Uganda, Zambia
Institute of Tropical Medicine, Belgium
KU Leuven; Institut National de Recherche Biomédicale. Kinshasa, République... and other collaborators

Completed

Health Itinerary of Young Children With Suspected Bloodstream Infection in Kisantu General Referral Hospital, DR Congo (HIT BSI)

Health Care Utilization | Bloodstream Infection | Febrile Illness | Malaria,Falciparum | Salmonella Infection Non-Typhoid

Congo, The Democratic Republic of the
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; Centre national de recherche et de formation... and other collaborators

Completed

P. Falciparum Infection Dynamics and Transmission to Inform Elimination (INDIE-1a)

Malaria

Burkina Faso
University of Cape Town
London School of Hygiene and Tropical Medicine; UMC Utrecht; Institut Pasteur; Institut... and other collaborators

Recruiting

Comparing a Novel Point-of-care Cytokine Biomarker Lateral Flow Test With Nucleic Acid Amplification Tests for Detection of Sexually Transmitted Infections and Bacterial Vaginosis (GIFT)

STI

Madagascar, South Africa, Zimbabwe
University of Washington
London School of Hygiene and Tropical Medicine; National Institute of Allergy... and other collaborators

Active, not recruiting

Field Studies on the Feasibility of Interrupting the Transmission of Soil-transmitted Helminths (STH)

Filariasis | Helminthiasis

India, Benin, Malawi
Erasmus Medical Center
University of Calgary; Institute of Tropical Medicine; Indonesia University; Utrecht... and other collaborators

Not yet recruiting

Impact of Reducing Colistin Use on Colistin Resistance in Humans and Poultry in Indonesia (COINCIDE)

Antimicrobial Resistance | Colonization, Asymptomatic | Colistin | Mcr-1

Indonesia
Finnish Institute for Health and Welfare
Karolinska Institutet; Peking University; Fudan University; Chongqing Medical University and other collaborators

Completed

Intervention on Maternal Health Care in Rural China (CHIMACA)

Maternal Health

China
London School of Hygiene and Tropical Medicine
Mwanza Intervention Trials Unit, National Institute for Medical Research; York... and other collaborators

Active, not recruiting

Adding Male Single Dose HPV Vaccination to Female HPV Vaccination in Tanzania (Add-Vacc)

HPV Infection | Vaccine Preventable Disease

Tanzania
Medicines for Malaria Venture
Sanaria Inc.; Institute of Tropical Medicine, Belgium; Iqvia Pty Ltd; SGS Life... and other collaborators

Completed

Study in Blood Stage Malaria Infection After DVI of Cryopreserved P. Falciparum (NF54 Strain) Sporozoites

Protozoan Infections | Parasitemia | Malaria,Falciparum | Parasitic Disease

Belgium
London School of Hygiene and Tropical Medicine
Medical Research Council; University of Witwatersrand, South Africa; National... and other collaborators

Completed

Targeted Indoor Residual Spraying Against Malaria (TIRS)

Malaria

South Africa
London School of Hygiene and Tropical Medicine
United States Agency for International Development (USAID); Population Services... and other collaborators

Completed

Double-blinded Trial of Household-based Chlorination in India

Diarrhoea

India
London School of Hygiene and Tropical Medicine
National Institute for Medical Research, Tanzania; Ocean Road Cancer Institute... and other collaborators

Completed

Delivery, Uptake and Acceptability of HPV Vaccination in Tanzanian Girls

Cervical Cancer

Tanzania
Foundation for Innovative New Diagnostics, Switzerland
Ludwig-Maximilians - University of Munich; Heidelberg University; Swiss Tropical... and other collaborators

Active, not recruiting

TB-CAPT MTB/XDR Study

Tuberculosis | Diagnoses Disease | Resistance Bacterial

South Africa
University of Oxford
London School of Hygiene and Tropical Medicine; Medical Research Council; Wellcome... and other collaborators

Recruiting

A Study to Compare Different Antibiotics and Different Modes of Fluid Treatment for Children With Severe Pneumonia (SEARCH)

Pneumonia

Kenya
Kintampo Health Research Centre, Ghana
London School of Hygiene and Tropical Medicine; PATH; Kenya Medical Research... and other collaborators

Active, not recruiting

Strengthening the Evidence for Policy on the RTS,S/AS01 Malaria Vaccine (MVPE-CC)

Malaria

Ghana, Kenya, Malawi
Institute of Tropical Medicine, Belgium
Drugs for Neglected Diseases; Medecins Sans Frontieres, Netherlands; Addis Ababa... and other collaborators

Completed

Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study

HIV-infection/Aids | Visceral Leishmaniosis

Ethiopia
Institute of Nutrition of Central America and Panama
National Heart, Lung, and Blood Institute (NHLBI); Institute for Clinical Effectiveness... and other collaborators

Completed

Multicomponent Intervention to Improve Hypertension Control in Central America

Arterial Hypertension

Guatemala
Klaus Reither
Radboud University Medical Center; Charite University, Berlin, Germany; University... and other collaborators

Completed

Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis (TB TRIAGE+)

Covid-19 | HIV | Pulmonary Tuberculosis | Tuberculosis Diagnosis

Lesotho, South Africa
London School of Hygiene and Tropical Medicine
Emory University; University of California, Davis; Bill and Melinda Gates Foundation and other collaborators

Completed

Cluster Randomised Trial of Improved Sanitation in Rural Orissa, India

Nutritional Status | Diarrhoea | Soil-transmitted Helminth Infection

India
London School of Hygiene and Tropical Medicine
University of Copenhagen; National Institute for Medical Research, Tanzania; University... and other collaborators

Recruiting

Long-term Health After Severe Acute Malnutrition in Children and Adults: the Role of the Pancreas (SAMPA)

Diabetes | Malnutrition | Pancreas Atrophy

Zambia, India, Philippines, Tanzania
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; University of Copenhagen; University... and other collaborators

Completed

Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa (IMPROVE)

Pregnancy | Malaria | Malaria in Pregnancy

Kenya, Malawi, Tanzania
SEAMEO Regional Centre for Food and Nutrition
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Recruiting

Egg Intervention During Pregnancy in Indonesia (PRECODE)

Protozoan Infections | Birth Weight | Weight Gain | Vitamin A Deficiency | Folate Deficiency | Zinc Deficiency | Child Development | Salmonella Infections | Anemia, Iron Deficiency | Fatty Acid Deficiency | Birth Length | B12 Deficiency Vitamin | Mineral Deficiency | E. Coli Infection | Shigella Infection | Amino Acid Deficiency and other conditions

Indonesia
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; University of California, San Francisco; Medical... and other collaborators

Recruiting

P. Falciparum Infection Dynamics and Transmission to Inform Elimination (INDIE-1b)

Malaria

Gambia
Harvard School of Public Health (HSPH)
National Institute of Allergy and Infectious Diseases (NIAID); Fogarty International... and other collaborators

Completed

Safety of Cotrimoxazole in HIV- and HAART-exposed Infants

HIV Infections | Acquired Immunodeficiency Syndrome | Anemia | Neutropenia | Infant, Newborn

Botswana
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; University of Turku; Imperial College London; University of Oxford and other collaborators

Active, not recruiting

Gambia Pertussis Study (GaPs) (GaPs)

Pertussis

Gambia
Institute of Tropical Medicine, Belgium
University of Manitoba; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Monkeypox, Biology, Outcome, Transmission and Epidemiology -Prospective Follow-up of High-risk Contacts (MBOTE-CONTACT)

Mpox

Congo, The Democratic Republic of the
Foundation for Innovative New Diagnostics, Switzerland
London School of Hygiene and Tropical Medicine; Leishmaniasis Research and... and other collaborators

Recruiting

Evaluation of Less Invasive Procedures for Visceral Leishmaniasis Treatment Efficacy Monitoring Test of Cure (VL-ToC)

Visceral Leishmaniasis

Ethiopia
Prof Gerhard Walzl
London School of Hygiene and Tropical Medicine; Makerere University; Leiden University... and other collaborators

Completed

Evaluation of Host Biomarker-based Point-of-care Tests for Targeted Screening for Active TB (ScreenTB)

Pulmonary Tuberculosis

United Kingdom, Uganda, Ethiopia, Gambia, Germany, Namibia, Netherlands, South Africa
Brigham and Women's Hospital
London School of Hygiene and Tropical Medicine; Yale University; Centers for... and other collaborators

Not yet recruiting

Prospective COVID-19 Cohort Study, Dominican Republic

Covid19 | SARS-CoV-2 Infection
Menzies School of Health Research
PATH; Indonesia University; Institute of Tropical Medicine, Belgium; UNITAID; Burnet... and other collaborators

Recruiting

Short Course Primaquine for the Radical Cure of P. Vivax Malaria - Indonesia (SCOPE)

Vivax Malaria | G6PD Deficiency

Indonesia
Institute of Tropical Medicine, Belgium
Drugs for Neglected Diseases; Institut National de Recherche Biomédicale. Kinshasa... and other collaborators

Withdrawn

Screen and Treat Implementation for HAT Control

Trypanosomiasis, African | Sleeping Sickness
Tulane University School of Public Health and Tropical...
Institute for Clinical Effectiveness and Health Policy; Laboratory of Parasitology... and other collaborators

Completed

Congenital Transmission of Lineages I and II of Trypanosoma Cruzi

Chagas Disease

United States, Argentina, Belgium, Honduras, Mexico
University of Cape Town
London School of Hygiene and Tropical Medicine; Fred Hutchinson Cancer Center; Aurum Institute and other collaborators

Unknown

The Correlate of Risk Targeted Intervention Study (CORTIS)

Tuberculosis

South Africa
University of North Carolina, Chapel Hill
London School of Hygiene and Tropical Medicine; Shandong University; National... and other collaborators

Completed

A Non-inferiority Randomized Controlled Trial to Evaluate Promoting Condom Use Among MSM and Transgender Individuals in China

Sexually Transmitted Diseases | Human Immunodeficiency Virus

China
Helen Keller International
London School of Hygiene and Tropical Medicine; University College, London; United... and other collaborators

Completed

SMS Messages to Increase Child Egg Consumption, a C-rct in Nepal

Dietary Habits

Nepal
Universiteit Antwerpen
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Makerere... and other collaborators

Completed

Impact of Artemisinin-based Combination Therapy and Quinine on Treatment Failure and Resistance in Uncomplicated Malaria (QuinAct)

Malaria

Congo, Uganda
Human Development Research Foundation, Pakistan
National Institute of Mental Health (NIMH); University of Washington; World Health... and other collaborators

Completed

School Health Implementation Network: Eastern Mediterranean (SHINE)

Behavioral Symptoms | Emotional Disorder | ADHD | Conduct Disorder | Emotional Stress | Depression, Anxiety | Emotional Problem | Behavioral Problem | Emotional Trauma

Pakistan
University of Minnesota
National Heart, Lung, and Blood Institute (NHLBI); Syracuse University; Liverpool... and other collaborators

Recruiting

Community-based Communication for Blood Donation in Ghana (C-CAD)

Increase Repeat Blood Donation Attempts Among First-time Donors

United States
Menzies School of Health Research
Aga Khan University; University of Melbourne; Universitas Sumatera Utara; Ethiopian... and other collaborators

Recruiting

Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and Primaquine (EFFORT)

Vivax Malaria | Malaria, Vivax | Plasmodium Vivax | Malaria Relapse

Cambodia, Ethiopia, Indonesia, Pakistan
London School of Hygiene and Tropical Medicine
Centers for Disease Control and Prevention; World Health Organization; Barcelona... and other collaborators

Completed

Comparison of Two Different Doses of Azithromycin for Treatment of Yaws

Yaws

United Kingdom, Ghana, Papua New Guinea
National Institute of Allergy and Infectious Diseases...
London School of Hygiene and Tropical Medicine; Institut National de la Santé... and other collaborators

Active, not recruiting

Partnership for Research on Ebola VACcinations (PREVAC)

Ebola Virus Disease

Guinea, Liberia, Mali, Sierra Leone
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Active, not recruiting

PRACTECAL-PKPD Sub Study (PRACTECAL-PKPD)

Multi-drug Resistant Tuberculosis | Pulmonary Tuberculosis | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa
University of Cape Town
London School of Hygiene and Tropical Medicine; Medical Research Council, South... and other collaborators

Unknown

Effect of Public Sector Antiretroviral Treatment Programme on Tuberculosis and Immunization Care

Tuberculosis

South Africa
Barcelona Institute for Global Health
London School of Hygiene and Tropical Medicine; Leiden University Medical Center and other collaborators

Terminated

Evaluation of Effectiveness of ALBENDAZOLIVERMECTIN Coformulation vs ALBENDAZOLE for Treatment of Intestinal Worms (ALIVE)

Helminthes; Infestation, Intestinal

Ethiopia, Kenya, Mozambique
London School of Hygiene and Tropical Medicine
University College London Hospitals; World Health Organization; RTI International and other collaborators

Terminated

Smartphone App for Taking Images of Conjunctivae

Trachoma

Tanzania
London School of Hygiene and Tropical Medicine
University College London Hospitals; World Health Organization; RTI International and other collaborators

Terminated

App-based Versus Slide-based Inter-grader Agreement (IGA) Test for Trachoma Graders

Trachoma

Tanzania

Clinical Trials Sponsored by Bernhard Nocht Institute for Tropical Medicine

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