Clinical Trials Sponsored by Cambridge University Hospitals NHS Foundation Trust (joint Sponsor)

Total 325 results

University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Automated Overnight Closed-loop Glucose Control in Young People With Type 1 Diabetes (APCam05)

Type 1 Diabetes

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Cambridge Temperature Concepts

Completed

Comparison of DuoFertility, LadyComp/BabyComp and Clearblue Monitors

Infertility

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Wellcome Trust

Recruiting

Residual Inflammation and Plaque Progression Long-term Evaluation (RIPPLE)

Myocardial Infarction | Coronary Artery Disease | Inflammation | Atherosclerosis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Wellcome Trust; University of Cambridge

Completed

Haemodynamic Effects of Apelin Agonists and Antagonists in Man in COPD With Raised Pulmonary Artery Pressures

Pulmonary Hypertension | COPD

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Cambridgeshire and Peterborough...

Recruiting

Sound and Vision: A Collaboration Between Service-users, Artists and the Public to Explore the Lived Experience of Hallucinations

Schizophrenia | Parkinson Disease | Hallucinations

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Cambridge Theranostics Ltd

Completed

TomVasc - Vascular Effects of Tomato Extract (TomVasc)

Stroke | Transient Ischemic Attack | Peripheral Vascular Disease | Ischemic Heart Disease

United Kingdom
Royal Marsden NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust; University Hospital Plymouth...

Unknown

Tissue Collection for Biomarkers Determining Resistance to Ibrutinib (CLARITY)

Mantle Cell Lymphoma | Chronic Lymphocytic Leukaemia

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline

Completed

Evaluating the Effect of Standard-of-care Erythropoiesis-stimulating Agents on Forearm Blood Flow in Nondialysis-dependent Subjects With Anaemia Associated With Chronic Kidney Disease. (OPERA-CKD)

Cardiovascular Diseases | Chronic Kidney Disease

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca

Completed

Investigating the Effects of AZD2014 Therapy Given Prior to Radical Prostatectomy in Men With High Risk Prostate Cancer (CaNCaP02)

Prostate Cancer

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca

Completed

Study of Olaparib (± Degarelix) Given to Men With Intermediate/High Risk Prostate Cancer Before Prostatectomy (CaNCaP03)

Prostate Cancer

United Kingdom
TidalSense
Cambridge University Hospitals NHS Foundation Trust

Completed

Chronic Obstructive Pulmonary Disease (COPD) Breathing Record Study (CBRS)

Pulmonary Disease, Chronic Obstructive

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline

Unknown

Validation of the Analysis Methodology Behind the Use of Quantitative 18F-FDG PET/CT to Assess Lung Inflammation (VERIFY)

Sarcoidosis | Lung Inflammation

United Kingdom
GlaxoSmithKline
Cambridge University Hospitals NHS Foundation Trust

Terminated

A Study to Assess Inflammation in Rheumatoid Arthritis Using Molecular Imaging Techniques

Arthritis, Rheumatoid

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Nottingham University... and other collaborators

Completed

FASter Insulin in Closed-loop Technology in Children (FAST-Kids)

Type 1 Diabetes Mellitus

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; University of Cambridge

Terminated

A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems (PRIME)

Drug-Related Side Effects and Adverse Reactions | Cardiovascular System Disease

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Wellcome Trust; British...

Active, not recruiting

Multi-modality Imaging & Immunophenotyping of COVID-19 Related Myocardial Injury (MIIC-MI)

Cardiovascular Diseases | COVID19

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Oxford University Hospitals... and other collaborators

Recruiting

Craniofacial Imaging With 3D MRI: an Alternative to Ionising Radiation

Craniosynostoses | Synostosis | Skull Deformity

United Kingdom
Cambridgeshire Community Services NHS Trust
Cambridge University Hospitals NHS Foundation Trust

Unknown

Exploring Interventions for Glue Ear During Covid-19 (BIG-C)

Hearing Loss, Conductive | Hearing Impaired Children | Glue Ear

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
British Heart Foundation

Completed

Simvastatin in Aneurysmal Subarachnoid Haemorrhage (STASH) a Multicentre Randomised Controlled Clinical Trial (STASH)

Subarachnoid Haemorrhage

United States
Cambridge University Hospitals NHS Foundation Trust
Antaros Medical

Recruiting

Effect of Glucagon and Glucagon-like Peptide-1 Co-agonism on Cardiac Function and Metabolism in Overweight Participants With Type 2 Diabetes (COCONUT)

Obesity | Type 2 Diabetes

United Kingdom
Owlstone Ltd
Cambridge University Hospitals NHS Foundation Trust

Completed

Non Inferiority Trial for Detection of nCOVID-19 Through Analysis of Exhaled Breath Aerosols

COVID

United Kingdom
Pneumacare Ltd
Cambridge University Hospitals NHS Foundation Trust

Unknown

Validation of Structured Light Plethysmography - Health and Disease (SLP-RespDis)

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Arun Gupta
Cambridge University Hospitals NHS Foundation Trust

Withdrawn

Importance of Substance P in Intracranial Pressure Elevation Following Traumatic Brain Injury (NK1)

Traumatic Brain Injury
Karl Sylvester

Not yet recruiting

Forced Oscillation and Breathing Pattern in Asthma

Asthma
Mayo Clinic
Cambridge University Hospitals NHS Foundation Trust

Recruiting

Mayo AVC Registry and Biobank

Heart Diseases | Cardiovascular Diseases | Myocarditis | Cardiomyopathies | Ventricular Tachycardia | Cardiovascular Abnormalities | Sarcoidosis | Sudden Cardiac Death | Cardiac Arrhythmia | Cardiac Sarcoidosis | Sudden Cardiac Arrest | Arrhythmogenic Right Ventricular Cardiomyopathy | Arrhythmogenic Right Ventricular... and other conditions

United States, United Kingdom
Cambridge University Hospitals NHS Foundation Trust
HemoSonics LLC

Withdrawn

Clinical Evaluation of the Hemosonics Quantra® Coagulation Monitor in Liver and Multivisceral Transplantation

Liver Transplantation | Coagulopathy
Kathryn Beardsall

Completed

Point of Care Ketone Measurement in the Newborn (POCKET)

Hypoglycaemia

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Cytosystems Ltd

Unknown

Assessment of BladderLight SurvEILlance (ABSEIL)

Bladder Cancer
Anna Spathis

Completed

Fatigue Intervention Co-design Study in Teenagers and Young Adults With Cancer

Fatigue
James Tysome
University of Cambridge

Recruiting

The Accuracy of Sonotubometry to Assess the Eustachian Tube

Eustachian Tube Dysfunction

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
GE Healthcare; University of Cambridge

Active, not recruiting

Contrast Enhanced Spectral Mammography (CESM) Study (CONTEND)

Breast Cancer

United Kingdom
Maximilian Nussbaumer
Cambridge University Hospitals NHS Foundation Trust

Terminated

Mapping Sound Propagation Through the Human Lung for Better Diagnosis

Lung Neoplasms | Pulmonary Disease, Chronic Obstructive | Asthma | Lung Diseases, Interstitial | Bronchomalacia

United Kingdom
Pneumacare Ltd
Cambridge University Hospitals NHS Foundation Trust; University of Cambridge

Completed

Validation of Structured Light Plethysmography (SLPvsPNT)

Pulmonary Disease

United Kingdom
Adel Helmy
Cambridge University Hospitals NHS Foundation Trust

Unknown

Multimodality Monitoring Directed Management of Aneurysmal Subarachnoid Haemorrhage (MMMSAH)

Subarachnoid Hemorrhage, Aneurysmal
Daniela Elleri
Cambridge University Hospitals NHS Foundation Trust

Unknown

Closing the Loop in Young Children With Type 1 Diabetes

Type 1 Diabetes

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; European Commission

Completed

Closed Loop Glucose Control in Intensive Care Unit (CLASSIC)

Stress Hyperglycaemia

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust; Diabetes UK

Completed

Closing the Loop in Adults With Type 1 Diabetes (ANGELA01)

Type 1 Diabetes

United Kingdom
Sophie McKenny
University of Cambridge

Enrolling by invitation

Objective Measures of Cochlear Implant Electrode Position and Function

Cochlear Implants

United Kingdom
Joanne Outtrim
University of Cambridge

Unknown

Understanding Pre-operative Activity Levels in Elderly Patients

Physical Activity | Aging | Surgery

United Kingdom
Adel Helmy
Cambridge University Hospitals NHS Foundation Trust

Unknown

IL-1ra Dose-range Study for Moderate-to-severe TBI Patients (IL1ra)

Traumatic Brain INjury

United Kingdom
University of Edinburgh
Cambridge University Hospitals NHS Foundation Trust; NHS Lothian; Papworth Hospital... and other collaborators

Completed

18F-Fluoride Assessment of Aortic Bioprosthesis Durability and Outcome (18F-FAABULOUS)

Heart; Complications, Valve, Prosthesis
Joanne Outtrim
Cambridge Temperature Concepts

Completed

Study of Axillary Skin Temperature as a Marker of Ovulation

Infertility

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
The Christie NHS Foundation Trust; Bowel Disease Research Foundation

Unknown

Functional Outcomes Following Anal Cancer Treatment (FOFACT)

Anal Cancer

United Kingdom
University of Cambridge
University Hospital Inselspital, Berne; Cambridge University Hospitals NHS...

Completed

Closed-loop Insulin Delivery in the General Ward (ANGIE02)

Diabetes Mellitus

United Kingdom, Switzerland
University College, London
Cambridge University Hospitals NHS Foundation Trust

Completed

A Phase II MULTICENTRE Trial of Needle Based Laser Confocal Endomicroscopy of Cystic and Solid Tumours of the Pancreas (CONCYST)

Pancreatic Cyst | Cystadenoma, Mucinous | Intraductal Papillary Mucinous Neoplasm | Serous Cystadenoma

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
British Heart Foundation Cambridge Centre of Excellence

Completed

The Effect of Anacetrapib on Vascular Function and Arterial Stiffness (REVEAL-Vasc)

Atherosclerotic Cardiovascular Disease | Vascular Disease

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; University of Cambridge; MedImmune LLC

Active, not recruiting

A Series of Pilot Studies to Evaluate the haemoDynamic and mEtabolic Effects oF apelIn aNd rElaxin (DEFINE)

Cardiovascular Diseases | Type 2 Diabetes Mellitus

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
King's College London; University of Cambridge

Unknown

Trial of a Breathlessness Intervention Service for Intractable Breathlessness

Dyspnea

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge; Cancer Research UK Cambridge Institute

Completed

EVIS - Ex-vivo Assessment of T-lymphocyte Homing in Primary Pancreatic Cancer (EVIS)

Pancreatic Cancer

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Imperial College Healthcare NHS Trust; Royal Cornwall Hospitals Trust

Unknown

Assessment of Olfactory Dysfunction in SARS CoV-2 (COVID-19) Infection (ODYSSI)

Quality of Life | Anosmia | SARS-CoV-2 | COVID19 | Olfactory Disorder | Microsomia | Smell Disorder

United Kingdom

Clinical Trials Sponsored by Cambridge University Hospitals NHS Foundation Trust (joint Sponsor)

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