Clinical Trials Sponsored by EMS

Total 973 results

EMD Serono

Withdrawn

Atacicept Demonstrating Dose RESponSe (ADDRESS)

Systemic Lupus Erythematosus
EMD Serono

Terminated

Luveris® (Lutropin Alfa for Injection) in Women With Hypogonadotropic Hypogonadism (Luteinizing Hormone [LH] Less Than [<] 1.2 International Unit Per Liter [IU/L])

Hypogonadotropic Hypogonadism

United States
EMD Serono

Terminated

Safety and Efficacy of Treatment With Interferon Beta-1a Rebif® in Patients With Crohn's Disease

Crohn's Disease

Germany, Italy, Sweden, Switzerland, United Kingdom
EMD Serono

Completed

Cilengitide (EMD 121974) for Recurrent Glioblastoma Multiforme (Brain Tumor)

Glioblastoma Multiforme

United States
EMD Serono

Terminated

Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus

Advanced Solid Tumor

United States
EMD Serono

Completed

Effects of Matuzumab in Combination With Pemetrexed for the Treatment of Advanced Lung Cancer

Lung Cancer | Non Small Cell Lung Carcinoma

United States, Germany, Austria
EMD Serono

Completed

Sarizotan in Participants With Parkinson's Disease Suffering From Treatment Associated Dyskinesia

Parkinson's Disease | Dyskinesia

United States
EMD Serono

Completed

Rebif Advanced Magnetic Resonance Imaging (MRI) and Immunology Pilot Trial

Multiple Sclerosis

United States
EMD Serono

Completed

Relative Bioavailability of Pimasertib in Cancer Patients

Neoplasms

United States
EPS Corporation

Completed

Exploratory Study in Achievement of Improved Survival by Molecular Targeted Chemotherapy and Liver Resection for Not Optimally Resectable Colorectal Liver Metastases (ATOM ES)

Colorectal Cancer | Liver Metastasis

Japan
EPS Corporation

Completed

A Multicenter, Clinical Study of FOLFOXIRI With Bevacizumab As First-line Therapy in Patients With mCRC (QUATTRO)

Colorectal Neoplasms

Japan
EMD Serono

Terminated

MSC2015103B in Solid Tumors

Advanced Solid Tumor

United States
EMD Serono

Completed

Rebif® Rebidose® Versus Rebiject II® Ease-of-Use

Multiple Sclerosis, Relapsing-Remitting

United States
EMD Serono

Completed

Sarizotan in Parkinson Patients With L-dopa-induced Dyskinesia

Parkinson's Disease | Dyskinesia

United States, France, Germany, Bulgaria, Belgium, Hungary, United Kingdom, Romania, Canada, Portugal, South Africa
EMD Serono

Completed

A Study of the Safety and Effects of EMD 72000 in Subjects With Recurrent Ovarian Cancer

Ovarian Cancer

United States
EMD Serono

Terminated

A Multicenter Trial of Sprifermin (AS902330 [Recombinant Human Fibroblast Growth Factor-18]) or Placebo After Microfracture Surgery for Cartilage Injury of the Knee

Cartilage Injury of Knee
EMD Serono

Terminated

MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC)

Metastatic Colorectal Cancer

Italy, Spain, Belgium
EMD Serono

Completed

Retrospective Cohort Study of Rebif® Use in Pediatric Multiple Sclerosis (MS) Subjects (REPLAY) (REPLAY)

Multiple Sclerosis

Italy, Russian Federation, United States, Argentina, Venezuela, Canada, Tunisia, France
EMD Serono

Completed

Easypod United States User Trial

Growth Hormone Deficiency

United States
EMD Serono

Completed

A Study to Compare the Safety and Efficacy of Cetrotide® 3 Milligram (mg) Versus Antagon™ in Women Undergoing Ovarian Stimulation

Infertile Women Undergoing Assisted Reproductive Technology (ART)
EMD Serono

Completed

An Efficacy and Safety Trial of Serostim® in the Maintenance of the Treatment Effect Obtained During the Study of Serostim® in Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome

Human Immunodeficiency Virus Infections | Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome (HARS)
EMD Serono

Completed

Oocyte Cryopreservation Registry (HOPE Registry)

Oocyte Cryopreservation

United States
EMD Serono

Completed

12-week Study to Evaluate RebiSmart™ Suitability for Self Injection in Relapsing Multiple Sclerosis.

Multiple Sclerosis

United States, Canada, Germany, Italy, Spain, Sweden
EMD Serono

Terminated

Onercept in the Treatment and Re-Treatment of Subjects With Moderate to Severe Plaque Psoriasis

Arthritis, Psoriatic

United States, Canada
EMD Serono

Completed

Growth Hormone in the Treatment of HIV-Associated Wasting

HIV Infections | HIV Wasting Syndrome
EMD Serono

Terminated

A Phase I, Dose-escalation Study of AS703569 Given Orally to Subjects With Haematological Malignancies

Haematological Malignancies

Italy, United States, Switzerland, Belgium, Germany
EMD Serono

Completed

A Multicenter, Open-label, RebiSmart™ Autoinjector Ease of Use Study (Performs)

Multiple Sclerosis

United States
EMD Serono

Completed

The Multicenter, Open-label, Single-use Autoinjector Convenience Study

Multiple Sclerosis

United States
EMD Serono

Withdrawn

Implementation Study of Treatment Optimization Recommendations on Relapsing-Remitting Multiple Sclerosis (RR MS) Subjects

Relapsing-Remitting Multiple Sclerosis
Massachusetts General Hospital
Mount Auburn Hospital; Pro EMS

Withdrawn

Early Goal Directed Therapy in Sepsis by Emergency Medical Services

Sepsis

United States
EMD Serono

Completed

Prospective Observational Long-term Safety Registry of Multiple Sclerosis Participants Who Have Participated in Cladribine Clinical Trials (PREMIERE)

Multiple Sclerosis

United States
EMD Serono

Completed

First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies

Solid Tumor

United States
EMD Serono

Completed

Treatment of Abnormal Adipose Tissue Accumulation in Human Immunodeficiency Virus (HIV) Patients

HIV Infections | Lipodystrophy

United States, Canada
EMD Serono

Completed

Comparison of Anastrozole Verses Clomiphene Citrate in Stimulating Follicular Growth and Ovulation in Infertile Women With Ovulatory Dysfunction

Anovulation

United States
EMD Serono

Withdrawn

Determine if Either of 2 Doses of Study Drug Given With a Low-dose of Cyclophosphamide After a Complete or Partial Response to a Platinum-based Second-line Therapy in Women With Recurrent Ovarian Carcinoma Results in a Longer Time to Progression When Compared to the First Time to Progression.

Ovarian Cancer
EPS Corporation

Completed

Achievement of Improved Survival by Molecular Targeted Chemotherapy and Liver Resection for Not Optimally Resectable Colorectal Liver Metastases (ATOM)

Liver Only Metastasis From KRAS Exon 2 Wild Type (Under Protocol 1.0-1.2 Edition) and RAS Wild Type (Under Protocol 2.0 Edition) Colorectal Cancer

Japan
EMD Serono

Terminated

RESOunD: REbif Satisfaction On Discontinuing Oral Dimethyl Fumarate (RESOunD)

Multiple Sclerosis

United States
EMD Serono

Terminated

Sym004 in Subjects With Stage IV Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, Germany
EMD Serono

Terminated

Efficacy, Safety, and Tolerability of Plovamer Acetate (Pathway 1)

Relapsing Remitting Multiple Sclerosis

United States, Croatia, Bulgaria, Czech Republic, Italy, Mexico, Russian Federation, South Africa, Spain, Turkey, Hungary, Poland, Ukraine, Finland, United Kingdom, Greece, Serbia
EMD Serono

Terminated

Adherence Trial With MS LifeLines ® Services

Multiple Sclerosis | Relapsing-Remitting

United States
EMD Serono

Terminated

STRIDE - STimulating Immune Response In aDvanced brEast Cancer (STRIDE)

Breast Cancer

Czech Republic, Korea, Republic of, Russian Federation, South Africa, Germany, Slovakia, Austria, United States, Belgium, Poland, Israel, Australia
EMD Serono

Completed

The REbif® vs Glatiramer Acetate in Relapsing Multiple Sclerosis Pharmacogenetics Trial (REGARD-PGx)

Relapsing Multiple Sclerosis

United States
EMD Serono

Completed

A Safety and Efficacy Study of Oral Cladribine in Subjects With Relapsing-remitting Multiple Sclerosis (RRMS) (CLARITY)

Multiple Sclerosis, Relapsing-Remitting
EMD Serono

Completed

Prospective, Open-label Tolerability and Safety Monitoring Study of Novantrone in a Selected Cohort of Multiple Sclerosis Patients (RENEW)

Multiple Sclerosis

United States
EMD Serono

Completed

EMD 273066 in Patients With Recurrent EpCAM Positive Ovarian, Prostate, Colorectal or Non-small Cell Lung Cancers When First Given Cyclophosphamide

Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Carcinoma, Non-small-cell Lung

United States, Switzerland
EMD Serono

Terminated

First-in-Man, Dose-escalation Trial of c-Met Kinase Inhibitor EMD 1204831 in Subjects With Advanced Solid Tumors

Solid Tumors

United States
EMD Serono

Completed

ATS-1 Needle Free Injection Device Study-a Device for Administering r-hGH (Saizen) to Treat Growth Hormone Deficiency

Healthy
EMD Serono

Completed

A Prospective Study to Evaluate the Addition of Subcutaneous Recombinant Human-Luteinizing Hormone With Recombinant Human-Follicle Stimulating Hormone on Follicular Development in Women Undergoing Ovarian Stimulation for Assisted Reproductive Technologies

Infertility | Ovarian Stimulation
EMD Serono

Terminated

Saizen® Solution for Injection Adult Growth Hormone Deficiency (GHD) Immunogenicity Study

Growth Hormone Deficiency (GHD)

United States
EMD Serono

Completed

Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-onset Growth Hormone Deficiency

Pituitary Dwarfism | Childhood-onset Growth Hormone Deficiency

United States

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