Clinical Trials Sponsored by University Hospital Southampton NHS Foundation Trust

Total 3167 results

University of Portsmouth
University Hospital Southampton NHS Foundation Trust

Recruiting

Sweat Response, Sweat Composition and Thermoregulatory Response to Exercise in Heat in Adults With Cystic Fibrosis on Modulator Therapy. (Sweat-CF)

Cystic Fibrosis

United Kingdom
University of Portsmouth
University Hospital Southampton NHS Foundation Trust

Recruiting

Fitness, Body Composition, Physical Activity and Sleep Patterns in People With Cystic Fibrosis on Modulator Therapy. (Understand-CF)

Cystic Fibrosis

United Kingdom
John Carroll University
University Hospital Southampton NHS Foundation Trust

Active, not recruiting

Development and Validation of an Online Neurobehavioral Evaluation Tool for PTEN Patients

PTEN Hamartoma Tumor Syndrome

United States, United Kingdom
University Hospital Southampton NHS Foundation...
Sheffield Teaching Hospitals NHS Foundation Trust; University Hospitals, Leicester and other collaborators

Completed

CPET and Outcome After Oesophagogastric Cancer Surgery

Upper Gastrointestinal Disorders

United Kingdom
University Hospital Southampton NHS Foundation...
The Leeds Teaching Hospitals NHS Trust; University of Southampton; Newcastle-upon-Tyne... and other collaborators

Recruiting

Reconstruction in Extended MArgin Cancer Surgery (REMACS)

Quality of Life | Surgery--Complications | Abdominal Cancer | Pelvic Cancer

United Kingdom
University Hospital Southampton NHS Foundation...
University Hospitals Bristol and Weston NHS Foundation Trust; Oxford University... and other collaborators

Unknown

Respiratory Syncytial Virus (RSV) and Vaccination in Pregnancy

Respiratory Syncytial Virus (RSV) | Attitude | Maternal Vaccine Exposure

United Kingdom
University Hospital Southampton NHS Foundation...
Biosense Webster, Inc.

Not yet recruiting

Randomised Comparison of the Octaray and Pentaray Catheters (COPEC)

Atrial Fibrillation
University Hospital Southampton NHS Foundation...
EBR Systems, Inc.

Not yet recruiting

Implant of the WiSE CRT System With an Intracardiac Pacemaker (TLC)

Heart Failure
University of Southampton
Tameside Hospital NHS Foundation Trust; Bournemouth University; Southern Health...

Active, not recruiting

Planning for Frailty: Optimal Health and Social Care Workforce Organisation Using Demand-led Simulation Modelling (FLOWS)

Older People | Frailty in Aging

United Kingdom
University Hospital Southampton NHS Foundation...
Hoffmann-La Roche

Terminated

Atezolizumab, Rituximab, Gemcitabine and Oxaliplatin in Patients With Relapsed or Refractory DLBCL Not Suitable for High-dose Therapy (ARGO)

Diffuse Large B Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Relapsed Diffuse Large B-Cell Lymphoma

United Kingdom
University Hospital Southampton NHS Foundation...
Biosense Webster, Inc.

Completed

Late Potentials and Ablation Index in Ventricular Tachycardia Ablation

Ventricular Tachycardia

United Kingdom
University Hospital Southampton NHS Foundation...
BTG International Inc.

Unknown

Use of a Novel Radiopaque Embolic Agent in Prostatic Artery Embolisation for Symptomatic Benign Prostatic Enlargement

Benign Prostatic Hyperplasia

United Kingdom
University Hospital Southampton NHS Foundation...
Vascular Solutions LLC

Completed

Uterine Fibroid Embolization (UFE) for Symptomatic Fibroids: Comparison of Gel-Bead to Commonly Used Embolic Agents.

Uterine Fibroid | Embolization | Symptoms

United Kingdom
University Hospital Southampton NHS Foundation...
Asthma Allergy & Inflammation Research Trust

Recruiting

Severe Asthma Covid Vaccine Response Study (SHINE)

Coronavirus Antibody Levels

United Kingdom
University Hospital Southampton NHS Foundation...
Cancer Research UK; The Christie NHS Foundation Trust; Celldex Therapeutics; Oxford... and other collaborators

Active, not recruiting

A Combination of Rituximab and Varlilumab Immunotherapy in Patients With B-cell Lymphoma (RiVa)

B Cell Lymphoma

United Kingdom
University of Oxford
University College, London; University of Southampton; Moorfields Eye Hospital... and other collaborators

Completed

Gene Therapy for Blindness Caused by Choroideremia

Choroideremia

United Kingdom
University of Southampton
East Kent Hospitals University NHS Foundation Trust

Unknown

Family Factors in Young People With Diabetes: a Qualitative Study

Type 1 Diabetes

United Kingdom
Northampton General Hospital NHS Trust

Completed

Reduction of Pain Following Laparoscopic Surgery: A Double Blind Prospective Randomized Controlled Trial

Post-operative Pain

United Kingdom
University Hospital Southampton NHS Foundation...
Boston Scientific Corporation; Abbott

Recruiting

High Density Scar Guided Atrial Fibrillation Mapping (HD-SAGA)

Atrial Fibrillation

United Kingdom
University Hospital Southampton NHS Foundation...
AstraZeneca; Cancer Research UK

Completed

Open Label Phase I/Randomised,Double Blind Phase II Study in mCRPC of AZD5363 In Combination With DP Chemotherapy (ProCAID)

Prostate Cancer

United Kingdom
University Hospital Southampton NHS Foundation...

Completed

Capecitabine or Observation After Surgery in Treating Patients With Biliary Tract Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United Kingdom
University Hospital Southampton NHS Foundation...

Unknown

Follow-Up Study of Patients Who Have Undergone Surgery for Stage I, Stage II, or Stage III Colorectal Cancer

Colorectal Cancer

United Kingdom
University of Southampton
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust; Southern...

Completed

Treatment Burden in Parkinson's

Parkinson Disease | Parkinson

United Kingdom
St George's, University of London
University Hospital Southampton NHS Foundation Trust; St George's University...

Recruiting

Eosinophilic Oesophagitis Assessment With String Testing (EoEAST)

Eosinophilic Esophagitis

United Kingdom
Yeovil District Hospital NHS Foundation Trust
University of Southampton; University Hospital Southampton NHS Foundation Trust and other collaborators

Unknown

Frailty and Sarcopenia Outcomes in Emergency General Surgery (FrOGS)

Emergencies | Frail Elderly Syndrome | Sarcopenia | Surgery

United Kingdom
University of Birmingham
King's College Hospital NHS Trust; University Hospital Southampton NHS Foundation... and other collaborators

Not yet recruiting

Paediatric Early Rehabilitation & Mobilisation During InTensive Care (PERMIT) Feasibility (PERMIT)

Critical Illness | ICU

United Kingdom
University Hospital Southampton NHS Foundation...
University College London Hospitals; The Leeds Teaching Hospitals NHS Trust; University... and other collaborators

Unknown

Single Pulmonary Nodule Investigation (SPUtNIk)

Malignant Neoplasm of Lung

United Kingdom
University of Southampton
University of Nottingham; Norfolk and Norwich University Hospitals NHS Foundation... and other collaborators

Not yet recruiting

Cellulitis Optimal Antibiotic Treatment (COAT)

Cellulitis of Leg
University Hospital Southampton NHS Foundation...
Boston Scientific Corporation; Liverpool Heart and Chest Hospital NHS Foundation...

Completed

Boston Scientific COMET Wire Validation Study (COMET)

Stable Angina

United Kingdom
University of Hull
University of Southampton; Portsmouth Hospitals NHS Trust; University Hospitals...

Recruiting

Acceptability of an Interim Socket System (ASSIST)

Amputation

United Kingdom
University Hospital Southampton NHS Foundation...
Genzyme, a Sanofi Company

Completed

Clofarabine Pre-conditioning With Allogeneic Transplant for Acute Myeloid Leukaemia (AML)

Myelodysplasia | Acute Myeloid Leukaemia

United Kingdom
University Hospital Southampton NHS Foundation...

Unknown

Combination Chemotherapy and Rituximab in Treating Patients With Primary Mediastinal Diffuse Large B-Cell Lymphoma

Lymphoma

United Kingdom
Northampton General Hospital NHS Trust

Active, not recruiting

The Diabetes Transition Study for Young People Aged Between 16-20 Years of Age.

Type 1 Diabetes Mellitus

United Kingdom
Northampton General Hospital NHS Trust

Completed

Study Assessing the Position of Cricothyroid Membrane in Relation to Movement of Neck From Neutral to Extended Position (ULOC)

Difficult Intubation

United Kingdom
Northampton General Hospital NHS Trust

Unknown

Inhaler Technique Training

Obstructive Pulmonary Disease | Asthma Chronic
University Hospital Southampton NHS Foundation...
Warwick University Clinical Trials Unit

Not yet recruiting

Ventricular Fibrillation Following Out-of-hospital Cardiac Arrest

Ventricular Fibrillation | Cardiac Arrest, Out-Of-Hospital

United Kingdom
University of Southampton
Solent NHS Trust

Unknown

"The Lived Experience of Investigations for Sciatica"

Sciatica
Portsmouth Hospitals NHS Trust
University of Southampton

Recruiting

Does Engagement With Heritage Sites Have the Potential to Improve Sub-clinical Levels of Low Wellbeing in NHS Staff: A Feasibility Study. The HerWellNHS Study (HerWellNHS)

Mental Health Wellness 1

United Kingdom
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma (VAPOR)

Pancreatic Cancer | PDAC - Pancreatic Ductal Adenocarcinoma

United Kingdom
King's College London
King's College Hospital NHS Trust; University College London Hospitals; Cambridge... and other collaborators

Recruiting

The Clinical Impact of the Basophil Activation Test to Diagnose Food Allergy

Egg Allergy | Food Allergy | Food Allergy in Children | Milk Allergy | Food Allergy in Infants | Nut Allergy | Food Allergen Sensitisation

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Norfolk and Norwich University Hospitals NHS Foundation Trust; Luton and Dunstable... and other collaborators

Recruiting

EAGLET: EEG vs aEEG to Improve the Diagnosis of neonataL Seizures and Epilepsy (EAGLET)

Neonatal Seizures

United Kingdom
Oxford University Hospitals NHS Trust
Northampton General Hospital NHS Trust; University Hospital of Wales; Royal Berkshire... and other collaborators

Terminated

Observational Study of the LMA Protector (ADEPT1)

Airway Complication of Anesthesia

United Kingdom
Papworth Hospital NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust

Not yet recruiting

Validation of UK Protocols to Exclude Brain Blood Flow During Normothermic Regional Perfusion (NRP)

Cerebral Blood Flow
University of Manchester
King's College Hospital NHS Trust; Cardiff University; University College London... and other collaborators

Not yet recruiting

Immune Profiles in Myasthenia Gravis

Myasthenia Gravis
Papworth Hospital NHS Foundation Trust
King's College Hospital NHS Trust; The Leeds Teaching Hospitals NHS Trust; University... and other collaborators

Completed

Home Monitoring to Predict Exacerbation in Cystic Fibrosis (SmartCare)

Cystic Fibrosis

United Kingdom
The University of Northampton
Northampton General Hospital NHS Trust

Enrolling by invitation

Microbiology Studies of Acute Head and Neck Infections

Head and Neck Infection

United Kingdom
University of Bath
University of Southampton; Royal United Hospitals Bath NHS Foundation Trust; Great...

Completed

Mobilising Tumour and Immune Cells Via Exercise in Chronic Lymphocytic Leukaemia

Chronic Lymphocytic Leukemia | Minimal Residual Disease

United Kingdom
University of Southampton
University Hospital Southampton NHS Foundation Trust; National Institute for... and other collaborators

Completed

Development and Pilot Evaluation of a Web-supported Programme of Constraint Induced Therapy Following Stroke (LifeCIT)

Stroke

United Kingdom
University Hospital Southampton NHS Foundation...
Imperial College London; University of Bristol; University Hospitals Bristol... and other collaborators

Completed

Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study (StePS)

Sepsis

United Kingdom
University of Southampton
Solent NHS Trust

Withdrawn

Longitudinal Observation of NHS Staff Wellbeing Following Introduction of the I-care Peer Support App (I-Care)

Peer Group

United Kingdom

Clinical Trials Sponsored by University Hospital Southampton NHS Foundation Trust

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